1,974 research outputs found
La Paráfrasis de Isaac Argiro al Comentario Anónimo al Tetrabiblos de Tolomeo: Algunas Aportaciones Originales al Libro I
No full textA critical edition and Spanish translation of some relevant passages from Book I of Isaac Argyrus’ Byzantine paraphrase to the Anonymous Commentary on Ptolemy’s Tetrabiblos is first presented in this paper, as well as a translation from Argyrus’ paraphrase into Latin made in 16th century by an unknown humanist.Este artículo contiene la primera edición crítica y traducción castellana de algunos pasajes relevantes del libro I de la paráfrasis bizantina redactada por Isaac Argiro (s. XIV) a partir del Comentario Anónimo al Tetrabiblos de Tolomeo, así como de la traducción latina realizada sobre la paráfrasis de Argiro (s. XVI) por un humanista desconocido
Primary ciliary dyskinesia: clinical and genetic aspects
No full textPrimary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous disease, characterized by ciliary disfunction and impaired mucociliary clearance, resulting in a range of clinical manifestations such as chronic bronchitis, bronchiectasis, chronic rhino-sinusitis, chronic otitis media, situs viscerum inversus in almost 40-50% of cases and male infertility. The triad situs viscerum inversus, bronchiectasis and sinusitis is known as Kartagener syndrome. Up to now little is known about genetic, diagnostic and therapeutic aspects of primary motile ciliary diseases in children: for this reason, diagnosis is generally delayed and almost all treatments for PCD are not based on randomized studies but extrapolated from cystic fibrosis guidelines. The aim of this review is to propose to pediatricians a summary of current clinical and diagnostic evidence to obtain better knoledwge of this condition. The earlier diagnosis and the right treatment are both crucial to improve the prognosis of PCD
Splenoportal-mesenteric axis thrombosis and splenic artery occlusion as initial presentations of COVID-19 disease
No full textTra i libri di Isacco Argiro
No full textThis book reconstructs the figure of Isaac Argyrus, a byzantine scholar active in Constantinople of the 14th century, with due regards to the context of his work. The paleographical and codicological analysis of his book collection forms the basis for the considerations on the role he played as both a copyist in the transmission of classical works and an author in the contemporary hesychast controversy
O-glycosylation of the transcription factor SPATULA promotes style development in Arabidopsis
No full textO-linked β-N-acetylglucosamine (O-GlcNAc) and O-fucose are two sugar-based post-translational modifications whose mechanistic role in plant signalling and transcriptional regulation is still largely unknown. Here we investigated how two O-glycosyltransferase enzymes of Arabidopsis thaliana, SPINDLY (SPY) and SECRET AGENT (SEC), promote the activity of the basic helix–loop–helix transcription factor SPATULA (SPT) during morphogenesis of the plant female reproductive organ apex, the style. SPY and SEC modify amino-terminal residues of SPT in vivo and in vitro by attaching O-fucose and O-GlcNAc, respectively. This post-translational regulation does not impact SPT homo- and heterodimerization events, although it enhances the affinity of SPT for the kinase PINOID gene locus and its transcriptional repression. Our findings offer a mechanistic example of the effect of O-GlcNAc and O-fucose on the activity of a plant transcription factor and reveal previously unrecognized roles for SEC and SPY in orchestrating style elongation and shape
Endovascular Treatment of Critical Hand Ischemia: A Single-Center Experience
No full textPurpose: To clarify the role of endovascular treatment in patients with Critical Hand Ischemia of the distal upper extremity.Methods: From January 2012 to January 2017, 18 dialyzed patients presented chronic critical hand ischemia; 6 patients had a chronic occlusion of the ulnar artery and radial artery stenosis, 5 patients had a chronic occlusion of the radial artery and ulnar artery stenosis, 4 patients presented multiple stenosis of the ulnar, radial and interosseous arteries, 2 patients had only ulnar artery occlusion while one patient presented only radial artery occlusion. All patients underwent duplex ultrasound and a subsequent brachial angiography, in order to evaluate the distal run-off circulation. Revascularization was achieved via antegrade brachial puncture in all patients, with retrograde approach in 4 patients, with distal retrograde puncture in 3 patients and in one patient with loop technique.Results: No complications were observed during the periprocedural follow-up. One patient was not successfully revascularized (technical success rate: 94.4%). The patient had no direct flow after ulnar artery angioplasty. The procedure was clinical effective in 15 patients (clinical success rate: 83.3%). Clinical evaluation and Duplex-US were performed in the follow up period. TcpO2 evaluated in the perilesional skin surface increased from 20.2 +/- 6.5 mmHg to 53.8 +/- 13.1 mmHg in the follow up period (P < .01). We observed an improvement of pain, ulcers and infection healing in all treated remaining patients during the postoperative period.Conclusion: Percutaneous intervention prevents hand loss and functional impairment in patients with Critical Hand Ischemia and multiple comorbidities. (C) 2020 Elsevier Inc. All rights reserved
The Design and Experimental Validation of a Permanent Magnet Long-Stroke Gravity Compensator
No full textThe ever increasing demand for better and cheaper electronic devices, sensors, optical components, etc. fuels innovation in nanometer precision positioning machines. However, the overall architecture of these machines has not changed much over the past years. A huge improvement in the architecture is currently impossible due to a crucial element of these machines -- namely, the gravity compensator. A gravity compensator is a passive element providing a supporting force that reduces the heat generation of the actuators in the gravity direction. Additionally, the gravity compensator is required to have a low stiffness to limit the disturbance forces due to vibrations present inside the machine. The state of the art gravity compensators are based on permanent magnets, as they are a non-contact solution providing the best performance and excellent vacuum compatibility. However, the current designs are limited to a single operating point. To enable the development of the next generation of nanometer precision positioning machines, a gravity compensator with an operating line is required. Therefore, the goal of this research is: “To design and experimentally validate a magnetic long-stroke gravity compensator for a nanometer precision positioning machine”. In this study the most suitable magnetic design was developed using various modelling techniques. Subsequently, the model and the design were validated by means of measurements taken with an experimental setup. From this study it was concluded that the design requirements can be met using high grade magnets. Thereby, with this Master Thesis, the first step has been taken towards the next generation of nanometer precision positioning machines.Mechanical Engineering | Mechatronic System Design (MSD
Probing color coherence effects in pp collisions at √s = 7 TeV
No full textOpen Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the
source are credited. Funded by SCOAP3 / License Version CC BY 4.0.A study of color coherence effects in pp collisions at a center-of-mass energy of 7TeV is presented. The data used in the analysis were collected in 2010 with the CMS detector at the LHC and correspond to an integrated luminosity of 36 pb-1. Events are selected that contain at least three jets and where the two jets with the largest transverse momentum exhibit a back-to-back topology. The measured angular correlation between the second- and third-leading jet is shown to be sensitive to color coherence effects, and is compared to the predictions of Monte Carlo models with various implementations of color coherence. None of the models describe the data satisfactorily.BMWF and FWF (Austria); FNRS and FWO(Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil);MES
(Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF(Cyprus); MoER, SF0690030s09 and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland);
CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NIH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF and WCU (Republic of
Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, andUASLPFAI (Mexico); MBIE (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna); MON, RosAtom, RAS and RFBR(Russia);MESTD (Serbia); SEIDI and CPAN(Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); ThEPCenter, IPST, STAR and NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU (Ukraine); STFC (United Kingdom); DOE and NSF (USA)
Neutron spectrometer for fast nuclear reactors
No full textIn this paper we describe the development and first tests of a neutron spectrometer designed for high flux environments, such as the ones found in fast nuclear reactors. The spectrometer is based on the conversion of neutrons impinging on <sup>6</sup>Li into α and t whose total energy comprises the initial neutron energy and the reaction Q-value. The <sup>6</sup>LiF layer is sandwiched between two CVD diamond detectors, which measure the two reaction products in coincidence. The spectrometer was calibrated at two neutron energies in well known thermal and 3 MeV neutron fluxes. The measured neutron detection efficiency varies from 4.2×10<sup>-4</sup> to 3.5×10<sup>-8</sup> for thermal and 3 MeV neutrons, respectively. These values are in agreement with Geant4 simulations and close to simple estimates based on the knowledge of the <sup>6</sup>Li(n,α)t cross-section. The energy resolution of the spectrometer was found to be better than 100 keV when using 2.5 or 5 m cables between the detector and the preamplifiers
Development and expulsions. Study about the peasantry and agribusiness in the San José´s path in the Municipality of La Ceja, Antioquia
No full textRESUMEN : El fortalecimiento del sector económico es visto por muchas entidades territoriales como el motor de crecimiento para los demás sectores que componen el territorio y esto se hace evidente en la medida en que se examinan las facilidades que existen institucionalmente para el desarrollo del sector privado. Sin embargo, se pueden identificar realidades que demuestran que el desarrollo de la economía de un territorio no incluye necesariamente el crecimiento de aspectos fundamentales tales como los indicadores sociales, ambientales y culturales necesarios para configurar un desarrollo territorial integral. Por esto, este proyecto se centra analizar la manera en la cual la agroindustria genera expulsiones de campesinos manifestadas en lo social, lo económico y lo institucional en la vereda San José del municipio de La Ceja, en donde se permita conocer los contextos que han resultado del aumento de actividades agroindustriales y su relación con la población campesina y sus entornos.ABSTRACT : The strengthening of the economic sector is seen by many territorial entities as the engine of growth for the other sectors that make up the territory and this becomes evident as the facilities that exist institutionally for the development of the private sector are examined. However, realities can be identified that show that the development of the economy of a territory does not necessarily include the growth of fundamental aspects such as the social, environmental and cultural indicators necessary to configure a comprehensive territorial development. For this reason, this project focuses on analyzing the way in which agribusiness generates expulsions of peasants manifested in the social, economic and institutional aspects in the San José´s path of the municipality of La Ceja, where it is possible to know the contexts that have result of the increase in agro-industrial activities and their relationship with the peasant population and their environments.PregradoProfesional en Desarrollo Territoria
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