69,366 research outputs found
Supplementary Materials for 'Design of Factorial Experiments in Blocks and Stages'
No full textThis dataset contains the plots discussed in Chapters 4 and 5 and Appendix B and C of the thesis 'Design of Factorial Experiments in Blocks and Stages' by Emily Matthews, which was submitted for the degree of Doctor of Philosophy in July 2015. </span
Disruption of the developmental programme of Trypanosoma brucei by genetic ablation of TbZFP1, a differentiation-enriched CCCH protein
No full textThe regulation of differentiation is particularly important in microbial eukaryotes that inhabit multiple environments. The parasite Trypanosoma brucei is an extreme example of this, requiring exquisite gene regulation during transmission from mammals to the tsetse fly vector. Unusually, trypanosomes rely almost exclusively on post-transcriptional mechanisms for regulated gene expression. Hence, RNA binding proteins are potentially of great significance in controlling stage-regulated processes. We have previously identified TbZFP1 as a trypanosome molecule transiently enriched during differentiation to tsetse midgut procyclic forms. This small protein (101 amino acids) contains the unusual CCCH zinc finger, an RNA binding motif. Here, we show that genetic ablation of TbZFP1 compromises repositioning of the mitochondrial genome, a specific event in the strictly regulated differentiation programme. Despite this, other events that occur both before and after this remain intact. Significantly, this phenotype correlates with the TbZFP1 expression profile during differentiation. This is the first genetic disruption of a developmental regulator in T. brucei. It demonstrates that programmed events in parasite development can be uncoupled at the molecular level. It also further supports the importance of CCCH proteins in key aspects of trypanosome cell function
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Correspondence from Jas. A. Matthews to Hon. B. G. Humphreys, Washington, D. C., 1918 February 2
No full textCorrespondence from Jas. A. Matthews, Greenville, Mississippi, to Hon. B. G. Humphreys, Washington, D. C., 1918 February 2.
This will serve as an introduction to my son, J. A. Matthews, Jr., who has been called to Washington by the Department, and from his letters I surmise he is a little lonesome, not being placed just where he thought he would be. It is recognized by either of the Banks of Memphis, as well as the jobbing houses, that he is truly an expert accountant. It was this Department that called him to Washington. This is not a \u27chip off the old block\u27 but an improvement. Any courtesies that you can show the \u27kid\u27 will be duly appreciated .
The correspondence in this collection deals mainly with Mr. Matthews’ dealings as a civilian employee government auditor and efforts by himself and others close to him, to secure Matthews a commission as a government auditor.https://digitalcommons.memphis.edu/speccoll-mss-matthewsja1/1003/thumbnail.jp
[Jenny Matthews, Clifford B. Jones and R. C. Goodwin, 1966]
No full textPhotograph of three people taken on May 23, 1966. The accompanying press release states "PRESIDENT HONORED--Tech President Dr. R. C. Goodwin, was presented Tech Association of Women Students' Man of Distinction Award in surprise ceremonies Monday. AWS president Jenny Matthews of Andrews cited Dr. Goodwin's "many contributions to Tech" in making the award which also carries honorary membership in the student organization. Former Tech president Dr. Clifford B. Jones (left) is the only other male honorary member of AWS."
Measurement of the ratio of branching fractions B(B0→K∗0γ )/B(B0s→φγ ) and the directCP asymmetry inB 0→K∗0γ
No full textThe ratio of branching fractions of the radiative B decays B0→K⁎0γ and B0s→ϕγ has been measured using an integrated luminosity of 1.0 fb−1 of pp collision data collected by the LHCb experiment at a centre-of-mass energy of s√=7TeV. The value obtained is
B(B0→K⁎0γ)B(B0s→ϕγ)=1.23±0.06(stat.)±0.04(syst.)±0.10(fs/fd),
where the first uncertainty is statistical, the second is the experimental systematic uncertainty and the third is associated with the ratio of fragmentation fractions fs/fd. Using the world average value for B(B0→K⁎0γ), the branching fraction B(B0s→ϕγ) is measured to be (3.5±0.4)×10−5.
The direct CP asymmetry in B0→K⁎0γ decays has also been measured with the same data and found to be
ACP(B0→K⁎0γ)=(0.8±1.7(stat.)±0.9(syst.))%.
Both measurements are the most precise to date and are in agreement with the previous experimental results and theoretical expectations
Branching fraction and CP asymmetry of the decays B+→K0Sπ+ and B+→K0SK+
No full textAn analysis of B+ → K0
Sπ+ and B+ → K0
S K+ decays is performed with the LHCb experiment. The pp
collision data used correspond to integrated luminosities of 1 fb−1 and 2 fb−1 collected at centre-ofmass
energies of
√
s = 7 TeV and
√
s = 8 TeV, respectively. The ratio of branching fractions and the
direct CP asymmetries are measured to be B(B+ → K0
S K+
)/B(B+ → K0
Sπ+
) = 0.064 ± 0.009 (stat.) ±
0.004 (syst.), ACP(B+ → K0
Sπ+
) = −0.022 ± 0.025 (stat.) ± 0.010 (syst.) and ACP(B+ → K0
S K+
) =
−0.21 ± 0.14 (stat.) ± 0.01 (syst.). The data sample taken at
√
s = 7 TeV is used to search for
B+
c
→ K0
S K+ decays and results in the upper limit ( fc · B(B+
c
→ K0
S K+
))/( fu · B(B+ → K0
Sπ+
)) <
5.8 × 10−2 at 90% confidence level, where fc and fu denote the hadronisation fractions of a ¯b
quark
into a B+
c or a B+ meson, respectively
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Search for B-c(+) decays to two charm mesons
No full textA search for decays of B-c(+) mesons to two charm mesons is performed for the first time using data corresponding to an integrated luminosity of 3.0 fb(-1), collected by the LHCb experiment in pp collisions at centre-of-mass energies of 7 and 8 TeV. The decays considered are B-c(+)-> D-(s)(()*())(+) (D) over bar (()*()0) and Bc(+)-> D-(s)(()*D-)+(()*())(0), which are normalised to high-yield B+-> D-(s)(+)(D) over bar (0)decays. No evidence for a signal is found and limits are set on twelve B-c(+) decay modes. (C) 2018 The Author(s). Published by Elsevier B.V
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