Manisa Celal Bayar Üniversitesi Akademik Arşiv Sistemi
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Multi-level reranking approach for bug localization
No full textBug fixing has a key role in software quality evaluation. Bug fixing starts with the bug localization step, in which developers use textual bug information to find location of source codes which have the bug. Bug localization is a tedious and time consuming process. Information retrieval requires understanding the programme's goal, coding structure, programming logic and the relevant attributes of bug. Information retrieval (IR) based bug localization is a retrieval task, where bug reports and source files represent the queries and documents, respectively. In this paper, we propose BugCatcher, a newly developed bug localization method based on multi-level re-ranking IR technique. We evaluate BugCatcher on three open source projects with approximately 3400 bugs. Our experiments show that multi-level reranking approach to bug localization is promising. Retrieval performance and accuracy of BugCatcher are better than current bug localization tools, and BugCatcher has the best Top N, Mean Average Precision (MAP) and Mean Reciprocal Rank (MRR) values for all datasets
Picturing asthma in Turkey: results from the Turkish adult asthma registry
No full textIntroductionNational data on asthma characteristics and the factors associated with uncontrolled asthma seem to be necessary for every country. For this purpose, we developed the Turkish Adult Asthma Registry for patients with asthma aiming to take a snapshot of our patients, thereby assigning the unmet needs and niche areas of intervention.MethodsCase entries were performed between March 2018 and March 2022. A web-based application was used to record data. Study outcomes were demographic features, disease characteristics, asthma control levels, and phenotypes.ResultsThe registry included 2053 patients from 36 study centers in Turkey. Female subjects dominated the group (n = 1535, 74.8%). The majority of the patients had allergic (n = 1158, 65.3%) and eosinophilic (n = 1174, 57.2%) asthma. Six hundred nineteen (32.2%) of the patients had obese asthma. Severe asthma existed in 670 (32.6%) patients. Majority of cases were on step 3-5 treatment (n: 1525; 88.1%). Uncontrolled asthma was associated with low educational level, severe asthma attacks in the last year, low FEV1, existence of chronic rhinosinusitis and living in particular regions.ConclusionThe picture of this registry showed a dominancy of middle-aged obese women with moderate-to-severe asthma. We also determined particular strategic targets such as low educational level, severe asthma attacks, low FEV1, and chronic rhinosinusitis to decrease uncontrolled asthma in our country. Moreover, some regional strategies may also be needed as uncontrolled asthma is higher in certain regions. We believe that these data will guide authorities to reestablish national asthma programs to improve asthma service delivery
Immunolocalization of ERK1/2 and p-AKT in normal endometrium, endometrial hyperplasia, and early and advanced stage endometrioid endometrial adenocancer and their prognostic significance in malignant group
No full textObjective: To analyze the expression patterns of extracellular signal-regulated kinase (ERK1/2) and phosphorylated (p)-AKT in the tissues of non-pathologic endometrium, endometrial hyperplasia, and early and advanced stage endometrioid endometrial adenocancer using indirect immunohistochemistry, and also to investigate the effect of ERK1/2 and p-ART expression patterns on prognosis in endometrioid adenocancer. Study design: Immunolocalization of ERK1/2 and p-Ala was examined in six different types of endometrial tissues: proliferative endometrium (PE; n = 10, 11.2%), secretuar endometrium (SE; n = 10, 11.2%), simple hyperplasia (SH; n = 15,16.9%), complex hyperplasia (CH; n=3, 3.4%) and atypical complex hyperplasia (ACH; n = 10, 11.2%), which were obtained from endometrial biopsies, curettage materials, and hysterectomy specimens and classified as the benign group; and both early stage endometrioid (n = 21, 23.6%) and advanced stage endometrioid adenocancer (AC; n=20, 22.5%), which were obtained from complete surgical staging materials and classified as the malignant group. All specimens were fixed in 10% formalin and processed using routine paraffin protocols. Immunostaining intensities were evaluated as negative or weak (assigned as low expression) and moderate or strong (assigned as high expression). Results: In the malignant group, 23 of 41 patients (56.1%) had high ERK1/2 and p-AKT expression, whereas only three of 48 patients in the benign group (6.3%) had high ERK1/2 and p-ART expression (P < 0.0001 and P < 0.0001, respectively), p-ART expression was significantly higher in women with positive lymph nodes (OR 9.0; 95% CI: 1.2-100.0; P = 0.03). Higher expression of p-Ala was significantly associated with poor progression-free survival (PFS) and overall survival (OS). In contrast, ERK1/2 expression was not associated with PFS or OS. Conclusions ERK1/2 and p-ART can be useful in the differential diagnosis of benign vs. malignant endometrial lesions, as well as early vs. advanced stage endometrioid endometrial adenocancer. Additionally, higher p-ART expression could be used as a marker of poor prognosis in the management of patients with endometrioid endometrial adenocancer. (C) 2014 Elsevier Ireland Ltd. All rights reserved
Optimal tuning of PI speed controller coefficients for electric drives using neural network and genetic algorithms
No full textThis paper presents a method of tuning Proportional Integral (PI) controller coefficients in the off-line control of a nonlinear system. In this method, the first step is the identification of the system via Artificial Neural Networks (ANNs), using maximum overshoot and settling time obtained from the application circuit for different K-p-K-i pairs. With this in mind, multi-layer ANN, which uses back-propagation of the error algorithm, was used as the learning algorithm. In the second step, the purpose is to find the optimum controller coefficients using the ANN model as the objective function via Genetic Algorithms (GAs). A Digital Signal Processor (DSP-TMS320C50) was used to carry out control applications. The C++ language was used for ANN and GA, and and the Assembly language was used for the DSP. It is determined that maximum overshoot and settling time are very small if the system is controlled by control parameters obtained from the optimization process that uses GA
An investigation on the elastic modulus and density of vacuum casted aluminum alloy 2024 containing lithium additions
No full textThe elastic modulus and density of (2024 + LiX) alloys are investigated, To the alloy of 2024, the weight percentages of lithium added are 2, 3, and 4, Melting is carried out in an induction furnace under argon gas protection; casting is done under vacuum. To obtain the maximum strength and hardness, the specimens are solution heat treated under 495 C and quenched in water at room temperature. Then, they are aged naturally and artificially. For the purposes of comparing, some of the specimens are merited under argon gas, but casting is done without vacuum. All the specimens are subjected to tension tests. As a result of this work, the alloys of aluminum that are difficult to manufacture by the known methods are manufactured safely by the vacuum casting method, For 1% of lithium added to the alloy, an increase of 6% in the elastic modulus and 3% decrease in the density are obtained. The specific elastic modulus, E/rho, ratio increases by about 10% for each 1% addition of lithium
Analytical solution for temperature field in electron and lattice sub-systems during heating of solid film
No full textThe analytical solution for non-equilibrium temperature field in solid substrate is presented. Closed form solutions for electron and lattice site temperature rise are obtained for a solid layer heated at the surface with a time-decaying intensity pulse. In the analytical solutions, a perturbation method of strained parameters is introduced. Temperature simulations are carried out for a gold layer with different thicknesses. It is found that increasing layer thickness lowers electron and lattice site temperatures at the surface. Electron temperature at the surface decays sharply with progressing heating period, which is more pronounced for thin layer. Moreover, lattice site temperature continues to rise despite reducing electron temperature in the surface region. The results obtained from the analytical solution for the lattice site temperature agrees well with the numerical predictions. (c) 2006 Elsevier B.V. All rights reserved
Development of a spiramycin sensor based on adsorptive stripping linear sweep voltammetry and its application for the determination of spiramycin in chicken egg samples
No full textHerein, an adsorptive stripping linear sweep voltammetric technique was described to determine spiramycin, a macrolide antibiotic, using a carboxylic multiwalled glassy carbon electrode modified with carbon nanotubes. The main principle of the analytical methodology proposed was based on the preconcentration of spiramycin by open-circuit accumulation of the macrolide onto the modified electrode surface. As a result of the adsorption affinity of spiramycin to the modified surface, the sensitivity of the glassy carbon electrode was significantly increased for the determination of spiramycin. The electrochemical behavior of spiramycin was evaluated by cyclic voltammetry and the irreversible anodic peak observed was measured as an analytical signal in the methodology. The proposed electrochemical sensing platform was quite linear in the range of 0.100-40.0 mu M of spiramycin concentration with a correlation coefficient of 0.9993. The limit of detection and the limit of quantification were 0.028 and 0.094 mu M, respectively. The intra- and interday repeatability of the proposed sensor was within acceptable limits. Finally, the applicability of the electrochemical methodology was examined by determining the drug content of chicken egg samples spiked with spiramycin standard. A rapid and easy extraction technique was performed to extract spiked spiramycin from the egg samples. The extraction technique followed had good recovery values between 85.3 +/- 4.0% and 93.4 +/- 1.9%
Validation and Reliability of The Frontal Assesment Battery (FAB) in Turkish
No full textScientific background: The Frontal Assessment Battery (FAB) test is a short test aiming to assess frontal lobe functions. It is composed of 6 items that give a total possible score between 0 and 18. The items include assessing the ability to find similarities between objects, categorical verbal fluency, resistance to interference, a simple go-no go paradigm, and peripheral autonomy. A higher score denotes better performance. Purpose: To determine the validity and reliability of the psychometric properties of the Turkish version of the Frontal Assessment Battery Method: The Turkish FAB was evaluated in 94 cases with diverse neuro-psychological conditions and in 92 healthy controls. Translation and back-translations of Turkish were done. In addition to FAB, the respondents completed a Standardized Mini Mental assessment scale, Stroop scale and a brief sociodemographic questionnaire. Reliability analysis involved test-retest reliability and internal consistency (alpha), whereas validity analysis involved factor analysis, convergent validity approach, known groups and criterion validity tests, and sensitivity analysis. Parametric and non-parametric correlations, T tests and ANOVA were used during these analyses. Findings: The alpha value was sufficient (alpha=0.73) for FAB but the alpha value decreased when the 6th item was deleted, indicating a problem with this item, as also confirmed by the factor solution. The fewer the years of education, the worse the FAB scale scores (p<0.001); men scored higher than women in a few items (mental flexibility, sensitivity to interference, and inhibitory control). The relationship between FAB and the Standardized Mini Mental Test (0.765, p<0.000) and Stroop scores indicated
Prevalence and evaluation of a choromogenic medium for isolation of Escherichia coli O157 from children with acute gastroenteritis
No full textObjective: Comparative performance status of CHROMagar O157 (CHROM) sorbitol-MacConkey (SMAC) media for the detection of Escherichia coli (E. coli) O157 in stool specimens isolated from 339 children under 5 years of age who presented with acute gastroenteritis between September 2008 and September 2010 was determined. Methods: Stool specimens were inoculated onto Sorbitol-MacConkey agar (SMAC), CHROMagar O157, Selenit F, Salmonella-Shigella (SS) and MacConkey agars. All plates were incubated aerobically for 24 to 48 h at 35 degrees C. Colorless colonies on the SMAC plate and mauve colonies on the CHROM plate were selected for further identification by conventional biochemical tests as well as by semi-automated system. Colonies confirmed to be E. coli were screened for O157 antigen by Dry spot E. coli O157 latex particle agglutination test. Results: In 339 stool samples examined, Salmonella spp was isolated in 14 (4.1%), and Shigella spp. in 11 (3.2%), while Escherichia coli O157 was detected in only 1 (0.3%) sample. Suspect E. coli O157 stains grew on 8 CHROMagar (2.1%; 8/339) and 14 SMAC (14/339; 3.8%) plates. Rate of false positivity for colony picks from SMAC (n= 13; 65%) media was almost 2-fold higher than that for CHROM (n= 7; 35%). Conclusion: Routine use of chromogenic media for the investigation of E. coli O157' nin in the selected cases with bloody diarrhea is deemed appropriate
A rare case liver hydatid cyst containing multiple calculi
No full textThe hydatic cyst disease, caused by Echinococcus granulosus, is a potentially lethal, which can be found anywhere in the world, but especially in endemic areas such as the Mediterranean Basin, North Africa, Eastern Europe, the Balkans and Middle East. This parasite is mainly found in the liver (3/4 of the cases), being asymptomatic in most cases and discovered accidentally on a routine abdominal ultrasound or an ultrasound done for diagnosing other pathologies. Liver hydatid cyst threatment is multimodal, which includes medical, surgical, and interventional radiologic techniques