335 research outputs found
Prefazione [a: Michail Kuzmin, Le stagioni dell'amore, Bari, Stilo, 2020, 172 pp.]
No full text"Kuranty ljubvi" (Le stagioni dell'amore) è un piccolo, ma poeticamente significativo, contributo alla produzione letteraria del Simbolismo russo nel segno della sintesi delle arti. Michail Kuzmin, uno dei più importanti scrittori di quell'epoca, è l'autore del ciclo poetico-musicale e delle partiture."Kuranty ljubvi" (The seasons of love) is a small but poetically significant contribution to the literary production of Russian Symbolism in the context of the synthesis of the arts. Michail Kuzmin, one of the most important writers of that era, is the author of the poetic-musical cycle and of the scores
Dei delitti e delle pene nella traduzione di Michail M. Scerbatov
Full text linkAfter more than two centuries, this work presents the Russian version of “Dei delitti e delle pene” by Cesare Beccaria, translated by Prince Michail M. Šcerbatov. The edition, conducted on the autographed manuscript, is presented with the original Italian text. In the introductory study, the author traces the fundamental stages of the diffusion of Beccaria’s work in Russia, focusing in particular on the figure of Michail M. Isaev, scholar and translator of the masterpiece by Beccaria, who was the first to re-propose the modern organisation of the “Fifth” edition. The author gives an account of the version proposed by Šcerbatov, investigating its textual genesis and evaluating some aspects of the language used by the translator - first of all the lexicon used for the rendering of philosophical-political and legal terms
Evidence-Informed Cardiometabolic Medicine
Full text linkDiseases that are rooted in an unhealthy Western lifestyle, i.e., type 2 diabetes, cardiovascular disease, and metabolic liver disease, are the most pressing global health issues today. These diseases co-occur and interact, particularly in the context of obesity, leading to heart failure, stroke, and premature death. This thesis responds to this growing burden by advancing tools that support earlier detection, personalized care, and treatment decisions, hallmarks of what is now emerging as cardiometabolic medicine.The first part presents questionnaire-based models that identify individuals at risk for type 2 diabetes and coronary artery disease. These models were tested across multiple ethnic populations and showed high accuracy, offering an accessible and scalable option for preventive screening, especially in underserved regions.The second part investigates whether adding data from scans or protein levels (proteomics) enhances risk prediction. Adding proteomics data into existing liver disease assessments indeed improves risk prediction for liver and secondary outcomes. Also, using brain imaging and proteomics, this research explores how obesity accelerates brain aging, uncovering sex-specific differences in neurodegeneration.Lastly, real-world health records from over 3 million individuals were used to evaluate how commonly used diabetes medications differ in the risk of cognitive decline. These results address a significant gap in clinical guidelines and inform drug selection in patients with type 2 diabetes.Collectively, these findings support the development of a firmly integrated form of evidence-informed care – cardiometabolic medicine – bringing together knowledge from endocrinology, cardiology, hepatology, and data science to tackle disease clusters with shared roots and overlapping trajectories
Impact of Solute Carrier Transporters in Glioma Pathology: A Comprehensive Review
Full text linkSolute carriers (SLCs) are essential for brain physiology and homeostasis due to their role in transporting necessary substances across cell membranes. There is an increasing need to further unravel their pathophysiological implications since they have been proposed to play a pivotal role in brain tumor development, progression, and the formation of the tumor microenvironment (TME) through the upregulation and downregulation of various amino acid transporters. Due to their implication in malignancy and tumor progression, SLCs are currently positioned at the center of novel pharmacological targeting strategies and drug development. In this review, we discuss the key structural and functional characteristics of the main SLC family members involved in glioma pathogenesis, along with their potential targeting options to provide new opportunities for CNS drug design and more effective glioma management
Author Correction: Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context
No full textInternational audienceThe original version of this Article contained a typographical error in the spelling of the author Mikhail Kapralov, which was incorrectly given as Michail Kapralov. This has now been corrected in the PDF and HTML versions of the Article and in the accompanying Supplementary Information
Hybridity, Identity and Micro-cosmopolitanism in the Ionian 19th century
No full textThe Ionian Islands, a complex of seven islands off the west coast of the Greek peninsula, historically and culturally constitute a contact zone between the Greek-speaking world and the West. In the 19th century, the islands, a former Venetian colony, experienced French and British colonial power before their incorporation in 1864 to the Greek state. This study focuses on the process of transformation of hybrid, cosmopolitan pre-national cultural identities into national schemes of appropriation and affiliation. Here, cultural agents, networking across linguistic, cultural, confessional or other borders, are exemplified by the example of the Lountzis brothers and their special link to the German-speaking world, its philosophy and its poetics. In this study, translation is scrutinised as a field of identity negotiation. It is also understood as a gesture of kinship with larger literary communities in the wider spectrum of the mobility of knowledge and ideas enabled by 19th century mystical sectarianism. The author of this book traces local micro-cosmopolitanism in the form of readership and identity performance, while cosmopolitanism, nationalism and sectarianism are viewed as interacting factors in the transformation of cultural, social and national identities in 19th century Europe.
Michail Leivadiotis, Hybridity, Identity and Micro-cosmopolitanism in the Ionian 19th centur
"Laughing Word" in the Novel by Michail Bulgakov’s "The Mаster and Margarita"
Full text linkОсновна увага авторів зосереджена на розкритті специфіки комічного в романі М. О. Булгакова «Майстер і Маргарита», на використанні “чужого” слова, а також композиційних прийомів, що спричиняють виникнення комічних ефектів. Діапазон емоційних оцінок, які автор дає своїм комічним персонажам, дуже широкий: від в’їдливої іронії щодо членів літературної асоціації до гумористичних образів звичайних радянських громадян. У статті наведено приклади того, як М. О. Булгаков з нещадною іронією викриває порожнечу й штучність офіційно-канцелярського мовного стандарту, словесних штампів, що приховують справжню, природну сутність явищ. The relevance of the topic of this work is due to the attention of modern philologists to the personal aspect of language learning, to the study of linguistic means that characterize human intentionality; to the dynamic structure of the literary text associated with its existence in the communication “author – reader”. The main attention of the authors is focused on revealing the specifics of the comicality in Bulgakov’s novel «The Master and Margarita», using “someone else’s” words, as well as compositional techniques of representation, leading to comic effects. The range of emotional assessments that the author gives to his comic characters is very wide: from the scathing irony of the literary association memebers to the humorous images of ordinary Soviet citizens. The purpose of this article is to consider what stylistic devices are used by Michail Bulgakov to achieve comic and ironic effects in the novel «The Master and Margarita», creating images of characters. The purpose involves solving the following main tasks: – to consider the main types of comic - humor and irony and their functioning in the novel «The Master and Margarita»; – to identify and consider the basic techniques of organizing a comic text; – to identify and analyze the linguistic means of achieving a comic effect in the text of the novel by Michail Bulgakov. The article provides examples of how Bulgakov with ruthless irony exposes the emptiness and artificiality of the official-clerical language standard, verbal stamps that hide the true, natural essence of phenomena. He seeks to reflect genuine reality, not distorted by the “crooked mirror” of official bureaucratic phrases. The merry magical power of Bulgakov’s laughter is aimed at ridiculing the senseless reality that was idealized by official Soviet literature. There were clear signs of what Bakhtin called the “carnival worldview” and the spirit of ancient menippeiа in «The Master and Margarita»
Figs. 11–13. Heteroborips seriatus, habitus. 11 in Resurrection of Heteroborips Reitter, 1913 (Coleoptera: Curculionidae: Scolytinae) from Synonymy with Xyleborus Eichhoff, 1864
No full textFigs. 11–13. Heteroborips seriatus, habitus. 11) Female, dorsal view. Photograph from www.zin.ru\Animalia\Coleoptera, Author – Kirill V. Makarov. Used with permission as indicated on website; 12) Male, dorsal view; 13) Male, lateral view. Photographs in Figs. 12 and 13 by Boris Anokhin (ZISP) (Mandelshtam et al. 2018).Published as part of Mandelshtam, Michail Yu., Petrov, Alexander V., Smith, Sarah M. & Cognato, Anthony I., 2019, Resurrection of Heteroborips Reitter, 1913 (Coleoptera: Curculionidae: Scolytinae) from Synonymy with Xyleborus Eichhoff, 1864, pp. 387-394 in The Coleopterists Bulletin 73 (2) on page 392, DOI: 10.1649/0010-065X-73.2.387, http://zenodo.org/record/537214
From non-alcoholic fatty liver disease (NAFLD) to steatotic liver disease (SLD): an ongoing journey towards refining the terminology for this prevalent metabolic condition and unmet clinical need
Full text linkThe discrete and continuous berth allocation problem: models and algorithms
No full textFierce terminal competition and the need to maximize recourses utilization have led marine terminal operators to the development and application of a rich variety of Berth Scheduling Policies (BSPs). Container terminal operators seek for efficient BSPs that will reduce vessels turnaround time, increase port throughput, lead to higher revenues and increased competitiveness of the port, while at the same time keep customer satisfaction at desired levels. Several issues arise when defining the best BSPs for each port operator and the final decision depends on several factors that include the type and function of the port (dedicated or multi-user terminal, transshipment hub etc), the size and location of the port, nearby competition, type of contractual agreement with the vessel carriers etc. Some of these BSPs and issues have to a certain extend been captured by academic research, but still several attributes need to be investigated and included for these models to represent the state of the practice of container terminal operations.
In this dissertation we present new models and solution algorithms that portray different BSPs and attempt to capture the operational environment of a container terminal, while at the same time including attributes of the system that current models lack. The formulations and solutions of mathematical models presented herein, seek to optimally schedule vessels and/or quay cranes to berths in multi-user type of container terminals, without losing its applicability to the private type container terminals. The objective is to present models and algorithms that capture as much as possible of current container terminal operator practices, while minimizing the assumptions made about real world conditions that container terminals operate in.Ph.D.Includes bibliographical references (p. 194-200)
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