14 research outputs found

    Effect of Li<sup>3+</sup> Ion Irradiation on Ionic Transport Properties of Complexed Polymer Electrolytes

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    AbstractSwift heavy ion (SHI) irradiation effects on ionic conduction in the PVA-H3PO4 polymer electrolyte films have been investigated due to its variety of applications in electrochemical devices. Polymer electrolytes films are irradiated with 50 MeV Li3+ ions having five different fluences viz. 5x1010, 1011, 5x1011, 1012 and 5x1012 ions/cm2. It is observed that irradiation of the polymer electrolyte films with swift heavy ions shows enhancement in conductivity at lower fluences and decrease in conductivity at higher fluences. It appears that below the critical fluence, swift heavy ion irradiation increases the diffusivity of Li+ ion in the polymer electrolyte which provides larger pathways for ionic transport throughout the system. The temperature dependence of electrical conductivity variation has been used to compute the activation energy involved in conduction process.</jats:p

    Effective Ayurvedic management of Katigraha - A Case Report

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    Katigraha is the commonest encountered disease. It is the condition which is characterized by stiffness, pain and impaired functioning of Lumbar spine region due to vitiation of Vata in Katipradesh. Even though this condition is not life threatening but it hampers the daily activity. Kati itself is one of the seats of Vata Dosha and the root cause of disease is aggravated by Vata.&nbsp;&nbsp; According to Ayurveda, it involves the Dushti of Asthivaha Srotas. About 80% of the industrial population and 60% of the general population suffers from low back pain due to their wrong posture. Case Report - A female pateint of 38 year old working as a tailor came to our hospital having complaint with low back pain which radiates to left lower limb, tingling sensation in bilateral lower limb, numbness in left heel region, difficulty in walking, loss of appetite, indigestion and disturbed sleep due to pain. Aim and objective - To evaluate the efficacy of Ksheerbala Tail Matra Basti and Murivennam Tail Katibasti in Katigraha for relieving pain, stiffness and impaired functioning of Lumbar spine. Result - Patient got marked relief in the pain, stiffness and tingling sensation along with improvement in walking. We will discuss the details in full paper. Conclusion - Katigraha is a common disorder of present era which is Vata Pradhan Tridoshaj Vyadhi in Ayurveda. Through this study we can conclude that Matra Basti with Ksheerbala Tail and Kati Basti with Murivennam Tail are effective in reducing the symptoms of Katigraha

    Sustainable wood microfluidics for versatile electrochemical studies with proof-of-concept application towards environmental nitrate sensing

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    The adoption of single-use plastics for fabricating lab-on-chip devices used in sensors, chemical and biomedical processes is escalating into a major environmental issue. To address the global need for developing long-term sustainable solutions, we present wood microfluidics as an alternative for electrochemical sensing. The lab-on-wood-chip (LOWC) device developed in this study demonstrated (i) versatility in electrochemical applications (electropolymerization and corrosion analysis), (ii) stability under highly acidic (pH 0.5), basic (pH 14.0) and varied temperature (4°–60 °C) conditions (iii) long-term consistency in performance (>12 months), and (iv) potential for on-field nitrate sensing towards environmental monitoring – in a cost-effective, simple and sustainable manner.This work has been supported by funding from the Maryland Industrial Partnerships (MIPS) award (#7104), Maryland Innovation Initiative (MII) TEDCO award (0923-0003) and the National Science Foundation (NSF) award (#2012340). Authors acknowledge the support from industrial collaborator Dietrich Ruehlmann, Managing Partner at GaiaXus, Maryland.https://www.sciencedirect.com/science/article/pii/S000926142500418X?via%3Dihu

    Light-induced electrolyte improvement in cobalt tris(bipyridine)-mediated dye-sensitized solar cells

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    Lithium-ion-free tris(2,2′-bipyridine) Co(ii/iii)-mediated electrolytes have previously been proposed for long-term stable dye-sensitized solar cells (DSSCs). Such redox systems also offer an impressive DSSC performance improvement under light soaking exposure, manifested by an increase in photocurrent and fill factor without the expense of decreasing photovoltage. Kinetic studies show that charge transfer and ion diffusion at the electrode/electrolyte interface are improved due to the light exposure. Control experiments reveal that the light effect is unambiguously associated with electrolyte components, [Co(bpy)3]3+ and the Lewis-base additive tert-butylpyridine (TBP). Electrochemical and spectroscopic investigation of the [Co(bpy)3]3+/TBP mixtures points out that the presence of TBP, which retards the electrolyte diffusion, however causes an irreversible redox reaction of [Co(bpy)3]3+ upon light exposure that improves the overall conductivity. This discovery not only provides a new strategy to mitigate the typical Jsc-Voc trade-off in Co(ii/iii)-mediated DSSCs but also highlights the importance of investigating the photochemistry of a photoelectrochemical system. Funding details: China Scholarship Council, CSC; Funding details: Energimyndigheten; Funding details: Vetenskapsrådet, VR; Funding text 1: We gratefully acknowledge the Swedish Research Council, the Swedish Energy Agency as well as the China Scholarship Council (CSC) for nancial support. The authors also thank Dr Lei Wang for his helpful assistance in 1H-NMR spectroscopic studies.</p

    Подходы к клинической разработке комбинированных лекарственных препаратов в Российской Федерации и Евразийском экономическом союзе с учетом требований действующего законодательства

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    In recent years, there has been an increasing interest in the development of combination medicines (fixed drug combinations) containing two or more active ingredients in a single dosage form. Therefore, there is an urgent need to develop an optimal programme of pre-authorisation clinical trials for combination medicines. The aim of the paper was to summarise modern science-based approaches to clinical development of combination medicines and identify possible ways of their practical implementation, taking into account the requirements of the current legislation. The author reviewed scientific publications devoted to creation of fixed drug combinations and analysed the regulatory documents defining regulatory requirements for pre-authorisation clinical studies of medicines in the Eurasian Economic Union, the Russian Federation, and other countries. Based on the results of the analysis the author described the general regulatory requirements for planning clinical studies of combination medicines for the purpose of their subsequent authorisation in the Russian Federation (via the national procedure) and the Eurasian Economic Union (via the centralized procedure). The pre-authorisation clinical development programme should be designed individually for each combination medicine. The selection of an optimal clinical trial strategy will make it possible to obtain sufficient information on the efficacy and safety of a combination medicine for its subsequent authorisation.

    Joint Consensus Statement – Safety Precautions for Doing Echocardiography and Image Acquisition During COVID-19

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    An echocardiographic investigation is one of the key modalities of diagnosis in patients suffering from COVID-19, especially if they are elderly, have associated comorbid conditions, and pregnant. Hence, it is becoming extremely essential to look into the correct safety precautions, health-care professionals must take while conducting an echo investigation. At the same time, a focused echo examination aimed at correct imaging view acquisition in the shortest possible time is the need of the hour. The decision matrix formulated for conducting an echocardiographic evaluation is based on the presence or absence of cardiological comorbidity vis-a-vis positive or suspected for COVID-19. The safety measures and image acquisition have been constructed keeping in mind the current safety precautions by the World Health Organization, the Centers for Disease Control and Prevention, and the Ministry of Health and Family Welfare, India

    GWTC-3: Compact Binary Coalescences Observed by LIGO and Virgo During the Second Part of the Third Observing Run

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    The third Gravitational-Wave Transient Catalog (GWTC-3) describes signals detected with Advanced LIGO and Advanced Virgo up to the end of their third observing run. Updating the previous GWTC-2.1, we present candidate gravitational waves from compact binary coalescences during the second half of the third observing run (O3b) between 1 November 2019, 15:00 UTC and 27 March 2020, 17:00 UTC. There are 35 compact binary coalescence candidates identified by at least one of our search algorithms with a probability of astrophysical origin pastro>0.5p_\mathrm{astro} > 0.5. Of these, 18 were previously reported as low-latency public alerts, and 17 are reported here for the first time. Based upon estimates for the component masses, our O3b candidates with pastro>0.5p_\mathrm{astro} > 0.5 are consistent with gravitational-wave signals from binary black holes or neutron star-black hole binaries, and we identify none from binary neutron stars. However, from the gravitational-wave data alone, we are not able to measure matter effects that distinguish whether the binary components are neutron stars or black holes. The range of inferred component masses is similar to that found with previous catalogs, but the O3b candidates include the first confident observations of neutron star-black hole binaries. Including the 35 candidates from O3b in addition to those from GWTC-2.1, GWTC-3 contains 90 candidates found by our analysis with pastro>0.5p_\mathrm{astro} > 0.5 across the first three observing runs. These observations of compact binary coalescences present an unprecedented view of the properties of black holes and neutron stars.Comment: 88 pages (10 pages author list, 31 pages main text, 1 page acknowledgements, 24 pages appendices, 22 pages bibliography), 17 figures, 16 tables. Update to match version to be published in Physical Review X. Data products available from https://gwosc.org/GWTC-3
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