4 research outputs found
Adalimumab in active ulcerative colitis: a "real-life" observational study
The effectiveness of adalimumab in the treatment of ulcerative colitis is under debate. Although controlled trials have shown that adalimumab is significantly better than placebo, the absolute clinical benefit is modest. We report data on the effectiveness of adalimumab in a cohort of ulcerative colitis patients treated in 22 Italian centres
Predictions for the rates of compact binary coalescences observable by ground-based gravitational-wave detectors
We present an up-to-date, comprehensive summary of the rates for all types of compact binary coalescence sources detectable by the initial and advanced versions of the ground-based gravitational-wave detectors LIGO and Virgo. Astrophysical estimates for compact-binary coalescence rates depend on a number of assumptions and unknown model parameters and are still uncertain. Themost confident among these estimates are the rate predictions for coalescing binary neutron stars which are based on extrapolations from observed binary pulsars in our galaxy. These yield a likely coalescence rate of 100 Myr(-1) per Milky Way Equivalent Galaxy (MWEG), although the rate could plausibly range from 1 Myr(-1) MWEG(-1) to 1000 Myr(-1) MWEG(-1) (Kalogera et al 2004 Astrophys. J. 601 L179; Kalogera et al 2004 Astrophys. J. 614 L137 ( erratum)). We convert coalescence rates into detection rates based on data from the LIGO S5 and Virgo VSR2 science runs and projected sensitivities for our advanced detectors. Using the detector sensitivities derived from these data, we find a likely detection rate of 0.02 per year for Initial LIGO-Virgo interferometers, with a plausible range between 2 x 10(-4) and 0.2 per year. The likely binary neutron-star detection rate for the Advanced LIGO-Virgo network increases to 40 events per year, with a range between 0.4 and 400 per year
0005
FUaiDKWT JORDAN RETURNS
A* O.
Prusidem Jordan relumed Friday
from s throe months' trip through
Japan, where be succeeded In securing
the largest snd moat oo_p_te collection ot Jspsseae Babe* ever obtained
by scientists.
I . ofeesnr J. O. Snyder, of tbe xool-
ogy department, wbo accompanied
him, gave out tbs following Information regarding tbs trip:
"Tbe IdeS In going to Japan wa* to
stake as complete a oollecUon and
study of th*> H*-h,ln Japanese wsteiVas
possible, snd, Incidentally, to lesrn
something of tbe oondltlon of tbe
Japanese people. In Japan were ae*
cui.il over 7000 specimens, which be
La taking back with him. Among tbem
sre 70 different kinds of nab, 125 of,
which sre unknown to science. ' aipta/
"TbeJspaoeaefiah bsve been studied. NtW
a . real tt*5m\ ny the Hutch, (German snd
Kngllsh, but tbe litersture Is very . -at-
tared, besldoa being product, in so
many different lavngi _gsw. It is th. Intention of Dr. Jordan to get together a
lsrge eollectloii and write a book on
Japanese fishes. It will lie in tbu nature
of s tegt book, so tbat the Ja*_n_*_
esn work with It, aa It Is alrunst Impos-'
sl bis for tbem to do anything with the CH.ASt*
flab of their own country at prt**»*-tit.
Two paper* have already been gotten
out by Dr. Jordan ou Che subjt_t, one
is Japan, now in press, and tbe otber
recently published hy the National
Museum.
"Mueb territory wss covered by tu
in tbe time at our dls.sal We visited
both the neat and seat oosst* and collected both salt and frueti water Ha be**.
We went aa far north as tb« Island
Hokkaido and as far south aa the Island l.i.-ukii-n Tht- largest coll actions
were in i'lf at Nagasaki, Wakantiurs.
Toklo snd at llakodatl. foil*. _tii_a or
descriptions wnni made of all hut fifteen
known species, besides VZ'< spraiee unknown to sclent.. Some si-rt- tld«- pool,
some off-abort-, some dt_p-ses fishes
and many were fresh-water fishes, obtained from rivers antl Inland lakes.
Tbe party stopped at Honolulu, both
going and coming, where collections
were also made.
"We were aided in our Held work by-
Mr. Abe snd by Mr. Utakl, both form _-
stutleuts at stanfi.nl They acted aa
guidia* snd IntSM-preters, sod were ol
great assistance as it ii almost Impossible to make any progreas without
such aiii. Tho local missionaries also
gave ua valuable aid. Tbey are a well*
sduosted people and seem to lie doing
good work. Probably tbe greatest aa-
sistsnee given ua, however, was by tbe
Imperial universities and by tbe officers
of the Imperial Pish Commission. Ws _u Univeralty
The Oak
Home Bakery
Freeh Bras., Hot Rolls, Pie* snd
Cakes delivered lo any part ot
loan daily. Strictly Home Baking
Salo Alto Agency of
The San Jose Laundry Association
At SLAOE'S BARBER SHOP
Next _ Bus
W.jftin will call for and dr.':-.—r -.uudry
M_U ordsr. promptly .llM.de. to-
PMONC SV
210 Homer Ave.
8c D.
UNCLE JOHN'S STABLES
Uncle John Is now in buslneaa
for himself snd the traveling
public will find him on band
with
CARRIAGES
and undiminished fund of
stories about all the points of
I uteri, t.
^
0
.0T
Lumber
^
_
_?
Millwork, Doors, Windows, Moulding, Tanks
...and all kinds of Building Material.,,
0r_ _ Yard ALMA STREET opp. DEPOT
PALO ALTO
PALO ALTO
BILLIARD PARLOR
ri.BA. J, SOU* *> ATBB.
rata Billiard •**> Pool . •'" ■*—
Farntln & Slado, Props.
PALO ALTO
H. L.
UPHAM
J Contractor
j and Builder
Meat Market
A. A. DULION, Proprietor
Government Inspected Refrigerated Meats
ii.-its. . ■-...-.; Sas_t_ aad Ur. .1 Mt-ai*
CHOI. K FlH'LTRY
Tel. Main IS
.'nivemtv Ave.
PLANS ruNNISMCO
Stop Paying Kent
.Ml Wi.fkt.ua.ai.li-i'.l
Hon- ■;■-.- S_S
i) V«a_ l. _- ii.-i.i.'
If y.tii ai-li t build a fasHi we t_u assist vim; don't pay for a l_ndlo_.V
houiat*. but pay for a house >A your own. See John F. Bysboe .. nt
for th.- Renter's Co-Operative investment Co. ■»*■ hsa
mtrney t>t Itian and st*ick for sale in tbia sulid and suecesaful .--.rp.ir.tt. n.
See him also for Insurance. as«I bargain, in town property & fruit ranches.
Rtaic-.ee 7ji tSlNSON ST.
P O. SOSStSS SOU 1ST SALO ALTO
Oeod Loaoa N ..tiaisd fur Hulldlac ITirpnsns
LIGHT CYCLERY
Y\ heels to lleot lUcych* Supplies
All kinds of Repairing solicited
m. A. Dlnemore
were ffiren five scerea to all the universities ssd
I'alo Alto
museums and tbe
r«*ry where
sra on r so ter prise
everywhere aeooed very friend
people
lly w-
1 The expedition was a complete suc-
ssaa. Tbe University now bss the largest collection of Jspsnoae flab _ In the
world—In fact, the coUectlon st 8t*o-
fo-tl Is larger than all the others In ths
world together. The I'nl versity already bss a txiDsctionJtbat waa mauV by
lhe United Ststea steamer Albatross
for tbe National Museum. The oolleo-
tlon just msde was carried free
by tbe Japanese steamers, ao that thu
cost of transportation will bs very
small. Dr. Jordan Is highly elated
over the sikhvs* of the trip, and It Is to
be res re-ted that his present sorrow
should i .tm* to cloud bis pleasure
"We were beautifully entertslned
while In Japan, tbe people were courte-
oua sod extremely hind to us. We
lived for the most part In Jai __-•*•
hotels, snd were enabled to study tbe
oomtntHt people as well aa tbe srlstoc-
raey The country it. -11 is fsr ad-
vsnosd In civilization snd eatreme ly
Interesting.
"Is Honolulu Dr. Jordso vlsiu*d tho
fish market, securing somessmplea cf ]
the fish there. Dr. Jordsn did sot so
so China, but be had many opportunities to study the situation In the Ksr
Esat. He declares thst tbe partition
Of Chios is ss lmposalbillfs. that al)
Europe bss no* men snd mooey enough
lo divide Chins ssd keep It divided.•* ,
J. E. FLANNELLY
CI
■f.
*-.
w
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e
a
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I_-__IMD_.
Eastman
B/crcus
Kodaks
ud
A
A
L.
L'
BICYCLES
R
Pishing
Tackle
V
mm
tr
©
QBB
6
•d
•_■
s—
Jt'
X
I.KAI.V.K IN
RAMBLERS
Hay and Grain
Wood and Coal
Feed, Flour. Bran and Produce of all kinds.
Iti.h atraat. Palo Alto
G. W. Mosher
Contractor
* Builder
Kstimst-a promptly furnisbsd on
sny kind of buildings - 1
PO Bo* 808 Pslo Alto j
Bstbs. Baths st Lsrkia's. ~~
LADIES
tUnne I «rl>
W. an niakinn Pall Suiu
in Twenty Different l"r_*ij.na
and are ,,fft-rmi.-
Special Hari-ains
li> making Suits to Order
(rijht here) including material Jacket silk linad at
$15.00
A. R. Allison
Ladies Tailor
I thi. pape. we SBM to. io*. ..
IRA A. SWAIN <_r
Palo till lid Umiiersitg .MESSENGER nd fUrchasing tjtit
orr i eta
l _lo Atfc_-_t_a_ a Sbos Stert*
■aa rrsacla*_-40 Third Htn. i
OvSar bos oonsar «*taa__ f_i»»r»it*t puau
TCLCSNONKS
*as rvaarlaao-TsI Ctav .
Pale Atie-TBl. Oaatral
•Bvra a_.r* an takra st w
Embedded Software of the KM3NeT Central Logic Board
The KM3NeT Collaboration is building and operating two deep sea neutrino
telescopes at the bottom of the Mediterranean Sea. The telescopes consist of
latices of photomultiplier tubes housed in pressure-resistant glass spheres,
called digital optical modules and arranged in vertical detection units. The
two main scientific goals are the determination of the neutrino mass ordering
and the discovery and observation of high-energy neutrino sources in the
Universe. Neutrinos are detected via the Cherenkov light, which is induced by
charged particles originated in neutrino interactions. The photomultiplier
tubes convert the Cherenkov light into electrical signals that are acquired and
timestamped by the acquisition electronics. Each optical module houses the
acquisition electronics for collecting and timestamping the photomultiplier
signals with one nanosecond accuracy. Once finished, the two telescopes will
have installed more than six thousand optical acquisition nodes, completing one
of the more complex networks in the world in terms of operation and
synchronization. The embedded software running in the acquisition nodes has
been designed to provide a framework that will operate with different hardware
versions and functionalities. The hardware will not be accessible once in
operation, which complicates the embedded software architecture. The embedded
software provides a set of tools to facilitate remote manageability of the
deployed hardware, including safe reconfiguration of the firmware. This paper
presents the architecture and the techniques, methods and implementation of the
embedded software running in the acquisition nodes of the KM3NeT neutrino
telescopes
