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Liquid and encapsulated duckweed (Lemna minor L.) extracts differentially shape metabolomic fingerprints of packaged beef burgers during shelf-life
Oxidative deterioration and color loss are critical factors limiting the shelf-life and consumer acceptance of fresh beef burgers under modified atmosphere packaging (MAP). This study evaluated Lemna minor (duckweed) extracts, applied in liquid form (LLE) and encapsulated with gum Arabic (AGL) or maltodextrin (ML), as natural antioxidants in beef burgers stored at 4 degrees C for 14 days. Extracts were tested at 0.1 %, 0.5 %, and 1 % (w/w), and their effects were assessed through physicochemical, microbiological, and untargeted metabolomics analyses. Encapsulation yields were high (similar to 80 %) for both carriers, with gum Arabic retaining higher antioxidant capacity. The liquid extract at 1 % and the encapsulated extracts at 0.1 % were the most effective treatments, preserving redness, reducing lipid oxidation below the sensory off-flavour threshold, and limiting oxygen consumption by day 7. Conversely, higher doses of encapsulated extracts (0.5-1 %) were less effective and in some cases induced pro-oxidant effects. Untargeted metabolomics revealed modulation of oxidative biomarkers, including glutathione, hemin, and tryptamine, supporting the antioxidant role of duckweed extracts in stabilising lipid and protein oxidation pathways. No antimicrobial effect was observed. These findings indicate that duckweed extracts can serve as sustainable, plant-based antioxidants for fresh beef burgers, with recommended application levels of 0.1 % (w/w) for encapsulated forms and 1 % (w/w) for liquid extracts. This represents the first demonstration of duckweed-based antioxidants in meat systems, offering a promising alternative to synthetic preservatives and supporting the transition toward clean-label strategies in the meat industry
I reati familiari con vittima minore
Il contributo approfondisce il sistema di reati a tutela del minore all'interno della comunità familiare
AGIS: navigare nella complessità lungo otto decenni e oltre
Il contributo analizza, nell'ambito dell'ottantesimo anniversario della costituzione dell'AGIS, Associazione Generale Italiana dello Spettacolo, come l'associazione abbia negli anni affrontato la complessità sociale, politica, economica legata alle trasformazioni del PaeseThe contribution analyses, in the context of the eightieth anniversary of the establishment of AGIS, the Italian General Association of Performing Arts, how the association has over the years addressed the social, political and economic complexity linked to the transformations of the country
Encyclopedia of agriculture and food systems III ed. Volume 5: Food, Agriculture, Society
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“Vieni da Nonna Tua, Vieni!” A commentary on the social construction of grandmothers and its impact on older women’s lives
Grandmother represents a biological denomination and a social construct with important implications in the everyday life of individuals worldwide. This concept is particularly important in occidental communities, with considerable emphasis on African, and South European and American countries, while it seems to have a lower, but not irrelevant, influence in North American communities [1]. The role grandmothers exert is multifactorial and involves multiple spheres of societies’ organization
Taming the Sea of Errors: An Ontological Study of Biases in DOLCE
In this paper, we present a preliminary ontology of bias based on the
DOLCE foundational ontology. The main reason for devising such an endeavour
is to make explicit the ontological assumptions behind the use of terms indicating
the elements composing a biased outcome. Firstly, we discuss what the object of a
bias is —namely, the entity that might be deemed biased, which we identify with
situated inferences, i.e. propositional contents that can be asserted by some (human
or artificial) agent from other propositional contents. We will thus categorise in
DOLCE various types of biases as concepts that classify situated inferences. The
content of such inferences is then associated with the following elements: i) the
agent responsible for drawing the conclusion, ii) the objects and iii) the concepts
used in the premises and in the conclusion of the inference, iv) the time when the
inference takes place. These ingredients will serve to trace the origin of what we
shall call a biased inference back to any of the above elements, relating some of the
biases present in the literature to these ontologically founded elements
Policy-sensitive crypto assets: Event study of thematic returns around U.S. elections
This paper analyzes how thematic crypto asset categories responded to the 2024 U.S. presidential election using cumulative abnormal returns (CARs) within an event study framework. We examine four thematic categories: Made in U.S., DeFi & Real-World Assets, AI & Big Data, and World Liberty Financial. The results show significant negative CARs in the pre-election window, followed by sharp positive reversals on the election day and after the election. The most pronounced post-election recoveries appear in the Made in U.S. category with CARs over 40 %, suggesting market reassessment of regulatory expectations. Innovation-driven categories such as (World Liberty Financial, DeFi & Real-World Assets, and AI & Big Data) exhibit more muted responses. These findings underscore how political alignment influences crypto performance and offer new evidence on the pricing of political risk in digital asset markets
Food heritage and sustainaibility. An ethnographic analysis
In recent years, the dialogue surrounding food has evolved significantly, shifting focus toward
its origins, quality, and, crucially, its sustainability (Albala, 2013). Sustainability, at its core, is
about meeting our present needs without compromising the ability of future generations to meet
theirs (Butler Harrington, 2016). It encompasses four main components: Economic, environmental, social, and cultural sustainability (Lazar & Chithra, 2022). These elements work in tandem to
ensure that food production systems are ecologically viable, economically feasible, and socially
equitable. Especially in the West, the lexicon of sustainability has become intertwined with that of
gastronomy, particularly over the last three decades (Corvo, 2015), when a new demand for food
began to emerge, distancing itself from mass productions, often lacking specific ties to the territories, and being increasingly interested in those products able to communicate history, a sense of
place, and cultural values (Cucinotta & Pieroni, 2018). Small-scale, local productions, with a deep
history and embedded in the life of communities’ food production, were recognized as a piece of
cultural heritage—a product
transmitted from generation to generation, [...] constantly recreated by communities and
groups in response to their environment, their interaction with nature and their history, and
[able to provide] them with a sense of identity and continuity, thus promoting respect for
cultural diversity and human creativity.
(Scovazzi, 2012, p. 179, see also, Smith & Akegawa, 2009)
Considering this, however, new questions emerge concerning traditional food productions,
their future, impact on the local environment, actual possibilities of development, and the maintenance of the meanings and practices that characterize and make them unique in the eyes of the
community.
Through a case study related to the process of rediscovery, reintroduction, and heritagization of
the pink asparagus of Mezzago, in Italy, this chapter aims to provide the reader with an initial tool
to reflect on some key questions related to both the very nature of food as a gastronomic heritage,
and the relationship and impact that the safeguarding and promotion of a food heritage can allo
Intranasal delivery of extracellular vesicles derived from human bone marrow mesenchymal stem cells dampens neuroinflammation and ameliorates motor deficits in a mouse model of cortical stroke
Early treatment of ischemic stroke can significantly reduce disability and mortality rates. Stem cell-derived extracellular vesicles (EVs) have shown potential as therapeutics for neurological disorders. This study explored whether intranasal administration of EVs from human bone marrow mesenchymal stem cells (BM-MSCs) enhances forelimb motor function recovery in a mouse model of motor cortex stroke and investigated their mechanism of action, focusing on neuroinflammation. C57BL/6JRj mice received EV treatment of 0.1 × 109 EVs per dose per day, 48 h post-stroke and twice weekly for four weeks. EV-treated mice showed significant improvement in forelimb deficits, as evaluated using a series of motor tests. Histopathological assessments revealed reduced infarct volume and decreased astrogliosis and microglial activation in EV-treated mice. EV treatment led to changes in microglial morphology in the peri-infarct area, associated with increased anti-inflammatory cytokines interleukin (IL)-10 and IL-13 and decreased pro-inflammatory cytokines IL-1β, IL-6, and tumor necrosis factor-alpha. Reduced expression of nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome and Cleaved Caspase-1 following EV treatment supports their role in dampening inflammation. In vitro experiments using oxygen-glucose deprivation confirmed that EVs attenuated the inflammatory phenotype of microglia and reduced neuronal apoptosis. EV cargo analysis revealed neuroprotective molecules, including anti-inflammatory cytokines and brain-derived neurotrophic factor (BDNF), which may contribute to their immunomodulatory properties. These findings show that EVs mitigate post-stroke brain immune response, promoting tissue healing and recovery. Our comprehensive characterization of the effects of human BM-MSC-derived EVs, encompassing functional, tissue, cellular, and molecular aspects, underscores their therapeutic potential and supports their use in stroke treatment
Active fund management when ESG matters
This paper develops and tests an equilibrium model of active fund management with ESG considerations. Heterogeneous sustainability preferences lead fund managers to intensify information acquisition on assets across the ESG spectrum, broadening the scope of active management. This information channel enhances price informativeness, lowers discount rates, and increases portfolio deviation from benchmarks. The model predicts a negative and concave ESG-expected return relation, stronger for green assets and weaker for brown assets. Using data on U.S. mutual funds and stocks from 2007–2021, we find supporting evidence based on price informativeness and the implied cost of equity capital