2 research outputs found
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Cuenoud Larissa
- Hassan Hardi
- Wynter Inez
- Rana Pratap
- Baker Pauline
- Gregory Bindu
- Stephen J
- Dodd Angela
- Orugun Enoch
- Chamberlain Angela
- Sutton Patrick
- Hansen Christian
- Hunter Neil
- Ramachandran Sankaranarayana
- Osborn Mairead
- Andole Sreeman
- Adedoyin Temi
- Sekaran Lakshmanan
- Wiltshire Alison
- Stevens Stephanie
- Smith Andrew
- Dacey Lynne
- Nicolson Anne
- Luder Robert
- Carrie Johanna
- Board Sarah
- Ball Julie
- Deary Ann
- Al-Mayhani Talal
- Sutton Victoria
- Cosier Tracey
- Sims Don
- Yip Brigitte
- Tomlin Dawn
- Oji Nnebuife
- Harrison Thomas
- Elliott Emma
- Davis Michelle
- Brown Claire
- Saulat Afaq
- Jeffs Carol
- Glass Jon
- Sanyal Ranjan
- Bell Murdina
- Ashton Amy
- Rashmi Sindhu
- Ballantine Robert
- Fong Rosanna
- Dobson Tracey
- Watson Fran
- McGhee Caroline
- Jagpal Baljit
- Charles Bethan
- Dhar Saikat
- Tanate Alfonso
- Grocott Jeanette
- Humphreys Louise
- Leason Sandra
- Burssens Evelyne
- O'Loughlin Victoria
- Evans Rachel
- Thavanesan Kamy
- Balazikova Olga
- Krishnamoorthy Shrivakumar
- Kerin Lourda
- Smyth Nigel
- Butler Rebecca
- Webb Tom
- Bowring Angela
- Baliga Vidya
- Carpio Racquel
- Perry David
- Harrington Frances
- Dakin Katy
- Dima Sofia
- Bayliss Pauline
- McIlmoyle James
- Gainard Glyn
- Walstow Deborah
- Lindert Ralf
- Perez Jane
- Hazel Beth
- Imam Javed
- Finney Kay
- Welch Angela
- Emberson Jonathan
- Jackson Benjamin
- Fraser Ruth
- MacInnes Brian
- Guo Fenglin
- McArdle Damian
- Ewing Jordan
- Macleod Malcolm
- Sangster Graeme
- MacRaild Allan
- Mangion David
- Campbell Robert
- Bathula Rajaram
- Doyle Clare
- Weinling Marie
- Khan Uzma
- Murali Elodie
- Kenton Antony
- Shackcloth Daniela
- Niranchanan Rangah
- Matthews Christopher
- Ingham Andrea
- Sandercock PAG
- Rahman Bithi
- Kambafwile Mary
- Waugh Dean
- Mohd Nor Azlisham
- Menon Nisha
- Quinn Leanne
- Fitzsimmons Paul
- Thorpe Kevin
- Gulliver Diane
- Thomas Isobel
- Azhar Khalid
- Smith Simon
- Sharpe Simon
- David Owen
- Morse Bethan
- Pettitt Kerry
- Dinsmore Lynn
- Kumar Pradeep
- Rajkumar Chakravarthi
- Fawcett Michelle
- Bridger Hayley
- Brew Helen
- Ross Sarah
- Vickers Carinna
- Patel Bhavini
- Bhargava Maneesh
- Williams-Yesson Barbara
- Jenkins Colin
- Orath Prabakaran Rajalakshmi
- Howard Peter
- Maanoosi Mehran
- Manoj Aravind
- Clarke Rebecca
- Redgrave Jessica
- Rudd Tony
- Davey Richard
- Thompson-Jones Helen
- Marigold James Richard
- Horan Kathleen
- Dodd Emily
- Khan Mohammad
- Srinivasan Meena
- Findlay Paul
- Roffe Christine
- McCormick Katrina
- Erumere Esther
- Black Toby
- Stephens Claire
- Kelly Christine
- Blair Caroline
- Hayman Rachel
- Slade Peter
- Whittamore Katherine
- Graham Carol
- Anthony Alpha
- Harrison Melanie
- Knops Kerstin
- Muddegowda Girish
- Denniss Carol
- Hunt Benjamin
- White Julie
- Thornthwaite Sarah
- Njoku Kelechi
- Humphries Fiona
- Holden Melinda
- Emsley Hedley
- Ravenhill Garth
- Joshi Yogish
- Amis Elaine
- Kane Ingrid
- Clarkson Emma
- Anjum Talat
- Gow Heather
- Tauro Suzanne
- Barber Mark
- Taylor Vicky
- Halse Omid
- Pound Susan
- Appleton Jason
- Pressly Vanessa
- Gainsborough Nicola
- Tucker Susan
- Strain David
- Wiggam Ivan
- Sangombe Mirriam
- Davies Caroline
- Kunhunny Swapna
- Chatterjee Kausic
- Macleod MR
- Shaw Kelly Marie
- Bruce David
- Madigan Barbara
- Baker John
- Hannon Niamh
- Egerton Shuna
- Butterworth-Cowin Nicola
- Davis Fiona
- Davies Ruth
- Keshvara Rekha
- Rudenko Hannah
- Fotherby Ken
- Doubal Fergus
- Kumar Balakrishna
- Alam Mohammad Irfan
- Dangri Puneet
- Krishnan Kailash
- Jarrett David
- Kini Manohar
- Elliot Jennifer
- Sattar Saira
- Thompson Teresa
- Steele Amy
- Smith Gemma Marie
- Rodgers Alicia
- Birchall Kathryn
- Needle Ann
- Constantin Carmen
- Butler Donna
- Subramonian Santhosh
- Gray Jane
- Verrion Anna
- Peixoto Cassilda
- Trippier Sarah
- Mardania Rina
- Szabo Susan
- Walters Ashleigh
- Dow Lindsey
- Jeyaraj Naomi
- Cronin Julie
- Tiwari Divya
- Willberry Angela
- Atkinson Natalie
- Parry Anthea
- Clarke Brian
- Tate Margaret
- Tandy Jane
- Argandona Lucia
- Robinson Naomi
- Stone Andrew
- Ramachandran Sankaranarayanan
- Stanners Andrew
- De Berker Henry
- Clarke Samantha
- Chenna Srikanth
- Mercer Lily
- Khan Shagufta
- Ford Gary
- Bhatnagar Priya
- Chandrakumar Aberami
- Symonds Stuart
- Howaniec Laura
- Young Andrew
- Owusu-Agyei Peter
- Bearne Helen
- Schulz Ursula
- Hughes Chloe
- Ali Ali
- Holmes Clare
- Shelton Faye
- Esisi Bernard
- Gallagher Jill
- Gupwell Karin
- Nasar Mohammad
- Rodriguez Aryelly
- Barry Adrian
- Orefo Chukwuka
- Tryambake Dinesh
- Day Nicola
- Kakar Puneet
- Crabtree Karen
- Myint Min
- Gautam Nikki
- Anversha Ajmal
- Dynan Kevin
- Mudd Paul
- Hussain Malik
- Saastamoinen Kari
- Mashate Sheila
- Putterill Janet
- Patel Champa
- McVerry Ferghal
- Nair Anand
- Tayler Michelle
- Triscott Claire
- Whiteman Jessica
- Cox Penelope
- Salehin Maqsud
- Gascoyne Rachel
- Nott Claire
- Harrington-Davies Yasmin
- Button Denise
- England Timothy
- Ingram Tanya
- Mate Abhijit
- Harkness Kirsty
- Tilley Victoria
- Auld Grace
- Barron Luke
- Gott Valerie
- Smith Fiona
- Ramadan Hawraman
- Kennedy James
- Moseley Sally
- Huggett Isabel
- Ferdinand Phillip
- Kullane Sagal
- Ovington Catherine
- Palmer Jeb
- Eveson David
- Willmot Mark
- Anderson Rosemary
- Hughes Tom
- Tomlinson Benjamin
- Stocks Kathy
- Walker Marion
- Rogers Gill
- Gilmour Danielle
- Ni Hlaing
- Godfrey Margi
- Mohammed Niaz
- Finlay Sarah
- Collins Kayleigh
- James Claire
- Woodward Stephen
- Sattar Naweed
- Gardener Léjeune
- Whitcher Alison
- Osborne Emily
- Brown Sarah
- Moroney Helen
- Marshall Sally
- Temple Natalie
- Lasserson Daniel
- Harvey Miriam
- Lucas Linda
- Whiting Robert
- Justin Frances
- Mitra Dipayan
- Tucker Laura
- Johnson Sharon
- Harvey Kirsten
- Wright Fiona
- Thompson Susan
- Muir Keith
- Klaasen Katrina
- Krishnamurthy Ramesh
- Gilham Ellie
- Choy Lillian
- Zachariah George
- Law Zhe
- Rayessa Rayessa
- Parakramawansha Ruwan
- Greenwood Richard
- Raj Sonia
- Brown Ellen
- Valentine Stacey
- McClelland Beverley
- Chaudhry Afnan
- Green Carole
- Kar Arindam
- Crisp Sarah
- Jose Deepa
- Handley Dominic
- Siddegowda Prasad
- Cunningham James
- Gaylard Jane
- Battersby-Wood Emma
- Jones Stephanie
- Sprigg Nikola
- Papavasileiou Vasileios
- Hyams Benjamin
- Innes Karen
- Shinh Naval
- Dickson Christine
- Haque Mohammad
- Walford Jamie
- Mcauley Sean
- Avis Joanne
- Cowie Linda
- Adil-Smith Jennifer
- Devitt Nicola
- Gilzeane Nicola
- Cheripelli Bharath Kumar
- Paulton Ruth
- Chadha Dinesh
- Saada Janak
- Downham Susan
- Bellfield Ruth
- Tribbeck Michele
- Venter Marius
- Grue Rebecca
- James Martin
- Ahmed Iman
- Bakawala Rehana
- Majmudar Nikhil
- Hayhoe Helen
- Clay Caroline
- Banaras Azra
- Vasileiadis Evangelos
- Lawrence Tara
- Sakka Eleni
- Turfrey Jennifer
- Perkins Charlotte
- Maddula Mohana
- Tallantyre Emma
- Bateman Gavin
- Rajapakse Anoja
- Crown Rachel
- Bell Angela
- Owoyele Emmanuelle
- Nguyen Vinh
- Mason Cathy
- Causley Chelsea
- Parry-Jones Adrian
- Balian Linda
- Gallifent Rachel
- Epstein Daniel
- Cassidy Tim
- Howard Joanne
- Beranova Eva
- Crook Luci
- Rinkel Gabriel
- Jagger Jenny
- Sudlow Cathie
- Clarke Judith
- Sheikh Saima
- Moreton Fiona
- Jennings-Preece Karla
- Dallol Bander
- Mcgee Joanne
- Siddiqui Anwer
- Lawson Heidi
- Kalladka Dheeraj
- Francia Nina
- McDonald Shanni
- Morgan Debbie
- Sword Jane
- Ward Deborah
- Amor Kelly
- Blades Alex
- Murray GD
- Doyle Donna
- Hove Dionne
- Dickinson Christina
- Culmsee Charlotte
- Mitchell Jennifer
- Duberley Stephen
- Abano Nenette
- Treadwell Shelley
- McAlpine Christine
- Murphy Peter
- Chapman Nicola
- Hostettler Isabel
- Whiteley William
- Adie Katja
- Eglinton Charlotte
- MacLiver Linda
- Broughton David
- Connor Lynda
- Macaden Ashish
- Miller Keniesha
- Allen Christopher
- Leggett Jacqui
- Graham Ruth
- Cox Chloe
- Kerr Gillian
- Guy Helen
- Richards Emma
- Barr Charlotte
- Bell Jo
- Ngo David
- Hooley Michaela
- Webster Timothy
- Kamara Christine
- Adesina Tolu
- Kingwell Hayley
- Boxall Cherish
- Hall Andrea
- Walker Allan
- O'Connell Susan
- Fletcher Glyn
- Shah Alex
- Kibutu Faith
- Price Fiona
- Garside Mark
- Ghaly George
- Wilson Sarah
- Butler Adrian
- Yadava Rajendra
- Goorah Neetish
- Amoils Shannon
- Krommyda Magdalini
- Elfandi Khaled
- Kalathil Latheef
- Williams Rebecca
- Majis Arshad
- Bergin Adrian
- Kelly Jim
- Creeden Robyn
- Hedstrom Amanda
- Metcalf Kneale
- Geraghty Olivia
- Evans Sue
- Fletcher Jo
- Clayton-Evans Lisa
- Musarrat Kashif
- Punter Martin
- Hurley Jennifer
- Blight Adrian
- Ahmad Nasar
- Blane Sujata
- Walker Susannah
- Gleave Laura
- Nyabadza Sheila
- Wilson David
- Hervey Simon
- Mokoena Betty
- Brodie Fiona
- Keltos Marketa
- Clarke Caroline
- Iqbal Mohammad Shahzad
- Smart Amanda
- Francis Jobbin
- Buxton Jean
- Cochrane Helen
- Fitzell Pauline
- MacLennan Beverly
- Jordan Carla
- Thomas Philip
- Pai Yogish
- Owings Paula
- Homan Jane
- Zoe Mellor
- King Sam
- Wallace Rebecca
- Keegan Breffni
- Raghunathan Senthil
- Marsden Tracy
- Wilkinson Mark
- Remegoso Alda
- Littleton Edward
- Howard Gabriella
- Bokhari Maria
- Glover Rachel
- Jose Josin
- O'Brien Eoin
- Crawford Pam
- Burger Ilse
- Foote Leanne
- Hunt Nicholas
- Grimwood Gemma
- Patel Farzana
- Devine Joseph
- Albazzaz Mo
- Wood Lisa
- Herman Jane
- Pawley Corinne
- Beaves Emily
- Sukdeo Varthi
- MacLeod Mary
- Chauhan Meena
- Kelly Siobhan
- Cvoro Vera
- Peters Jenny
- Patterson Chris
- Wallace Aine
- Sethuraman Sakthivel
- Mistri Amit
- Sinha Devesh
- Redjep Ozlem
- Pasco Kath
- Hemsley Anthony
- Edwards Mandy
- El Tawil Salwa
- Buchanan David
- Walter Deborah
- Milligan Josette
- McKee Jacqueline
- Sullivan Frank
- Crawford Susan
- Perfitt Rebekah
- Board Joanne
- Singh Arun
- McCann Stephanie
- McGill Connor
- Dutta Dipankar
- Cullen Claire
- Shekhar Raj
- White PM
- Hunter Annemarie
- Werring DJ
- Blair Gordon
- Wilson Jenny
- Mead Gillian
- Roberts Josh
- Richard Bella
- Cunningham Mishell
- Sultan Sulaiman
- Salek-Haddadi Afraim
- Dunne Karen
- Caine Sarah
- Hutchison Aidan
- Foot Jayne
- Wardlaw JM
- Quinn Outi
- Lambert Caroline
- Sharma Nikhil
- Choulerton James
- Kelly Debs
- Ispoglou Sissy
- Brezitski Maria
- Phiri Duke
- O'Reilly Joanna
- Thant Hlaing
- Persad Nicola
- Storton Sharon
- Bailey Duncan
- Maiden Susan
- Datta Prabal
- Sutton Claire
- Durairaj Ramesh
- Ngwako Mmua
- Veraque Emelda
- White James
- Buckle Steve
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- Krishnan Manju
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- Sykes Lucy
- Kennedy Kate
- Ullah Khalil
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- Stafford Samantha
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- Plewa Catherine
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- Hassan Ahamad
- Anwar Ijaz
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- Stevens Angela
- Salih Isam
- Markova Skarlet
- Pitt-Ford Alexandra
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- McCarron Mark
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- Krishnamurthy Vinodh
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- Wilson Lisa
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- Schwarz Stefan
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- Clayton Susan
- Newby DE
- Cohen David
- Baird Yolanda
- Patel Krishna
- Ahmed Ashraf
- Fuller Tracy
- Baigent Colin
- Lucas Suzanne
- Allison Joanna
- Reddan Julie
- Shukla Avani
- Horton Sarah
- du Plessis Johannes
- O'Connell Janice
- Walker Pauli
- Chadbourn Indra
- Qureshi Sammie
- McGrath Aileen
- Vettimootal Johnson Venetia
- Roughan Caroline
- Langhorne Peter
- Gbadamoshi Lukuman
- Clarke Natasha
- Lam Man Yee
- Robinson Matthew
- Pitt-Kerby Tressy
- Beaty Teresa
- Martin Irene
- Parker Richard
- Baig Farrukh
- Jha Ratneshwari
- Drever Jonathan
- Hairsine Brigid
- Amey Isobel
- Siddiq Muhammad
- Anwar Sajjad
- Dewar Richard
- Taylor Pat
- Nisar Nabeela
- Garcia Tatiana
- Jones Terry
- Moores Andrew
- Smith Wilma
- Haider Syed
- Hiden Joanne
- Doherty Mandy
- Ivatts Simone
- Weir Nic
- White Susan
- O'Toole Sarah
- Irvine Janice
- Hakim Eluzai
- Pusalkar Aparna
- Shread Ian
- Brown Pauline
- Joyson Anu
- Crouch Nichola
- Bharaj Kiranjit
- Armitage Jane
- Brotherton Lucy
- Ng Kheng Xiong
- Hague Adam
- Hardwick Anne
- Crosbie Caroline
- Werring David
- McLoughlin Alison
- Ankolekar Sandeep
- Williams Carol
- Bagnall Caroline
- Goff Anita
- Rai Baljinder
- Barker James
- Cageao Julie
- Oshodi Anne
- Donnelly Richard
- Cherian Suja
- Dennis Martin
- O'Brien Richard
- Dunn Linda
- James Ali
- Manning Lisa
- Cluckie Gillian
- Makawa Linetty
- Mathieson Philip
- Jelley Benjamin
- Penge Justin
- Wani Mushtaq
- Henry Margo
- Gattringer Thomas
- Nicholas Paul
- Gallagher Louise
- van Someren Chloe
- Birns Jonathan
- Wilkes Gwendoline
- Lee Stephanie
- Maguire Stuart
- Couser Mandy
- Alipio Francis
- Sesay Juliana
- Lerpiniere Christine
- Nelson Sandra
- Miriam Skelton
- Zahoor Tajammal
- Hughes Claire
- Buckley Clare
- Hyatt Lisa
- Reckless Ian
- Minks David
- Courtauld Gillian
- Sigsworth Andrew
- Khan Usman
- Blank Catrin
- Seagrave Samantha
- Lenti Giulia
- Ghosh Sandip
- Nasim Ashraf
- Schumacher Natasha
- Codd Laura
- Davies Silvie
- Carpenter Michael
- Sprigg N
- Cox Chantel
- Lyjko Sue
- Stevenson Sarah
- Guyler Paul
- Jupp Becky
- Beadle Hannah
- Maund Bev
- Latter Laura
- Little Victoria
- Jones Kirsty
- Feerick Shez
- Furnace Jacqueline
- Aweid Basaam
- Suttling Anne
- Roganova Tatjana
- Bates Michelle
- Thomson Audrey
- Burgess Laura
- Ragab Suzanne
- Bond Kirsty
- Spencer Jayne
- Newton Sophie
- Greig Jill
- Dayal Nilofer
- Durman Helen
- Dube Judith
- Ramshaw Alex
- Nozedar Tarn
- Shahmehri Shahrzad
- Wood Diane
- Al-Shahi Salman Rustam
- Publication venue
- Publication date
- 29/06/2019
- Field of study
No full textBackground Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events
Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?
- Author
- Cuenoud Larissa
- Hassan Hardi
- Nascimento B. R.
- Bililign N.
- Rai Rajesh Kumar
- Rana Pratap
- Sadaf G Sepanlou
- Behzadifar Meysam
- Montjoy-Venning Wcliff
- Naghavi Mohsen
- Alebel A.
- Sanjay Zodpey
- Rahman M.
- Sudlow Cathie L.M.
- Olivares P. R.
- Tabares-Seisdedos R.
- Dodd Angela
- Majdan Marek
- Mountjoy-Venning W. Cliff
- Ogbo Felix Akpojene
- Orugun Enoch
- Chamberlain Angela
- Sepanlou Sadaf G.
- Sutton Patrick
- Roever L.
- Hansen Christian
- Shiri Rahman
- Ramachandran Sankaranarayana
- Osborn Mairead
- Saddik B.
- Andole Sreeman
- Agrawal S
- Mendoza W.
- Shams-Beyranvand M.
- Gelaw Belayneh K
- Choi Jee-Young J
- Molokhia Mariam
- Wiltshire Alison
- Rezaeian S.
- Valdez P. R.
- Banstola A.
- Smith Andrew
- Ronfani L.
- Logroscino Giancarlo
- Sube Banerjee (4464202)
- Luder Robert
- Carrero Juan J.
- Hegazy Mohamed I
- Hay SI
- Moradi-Lakeh Maziar
- Milicevic Milena M. M. Santric
- Pan Wen-Harn
- Board Sarah
- Ball Julie
- Al-Mayhani Talal
- du Plessis Johann C.
- Sutton Victoria
- Cosier Tracey
- Banwell B.
- Walker Marion F
- Alene Kefyalew Addis
- Roshandel G.
- David Findlay (46833)
- Yip Brigitte
- Yano Y.
- Andrei CL
- Hosseini Seyed Mostafa
- Harrison Thomas
- Poustchi H.
- Alghnam SA
- Fischer F.
- Islam Sheikh Mohammed Shariful
- Zenebe ZM
- Saulat Afaq
- Iqbal Mohammad Shazad
- Reiner R. C.
- Bell Murdina
- Rashmi Sindhu
- Ives N
- Aboyans Victor
- Asayesh Hamid
- Dobson Tracey
- McGhee Caroline
- Banach Maciej
- Jagpal Baljit
- Rahman Mohammad Hifz Ur
- Tanate Alfonso
- Shigematsu M.
- Ali B. A.
- Igumbor Ehimario U.
- Samy Abdallah M.
- Rahimi-Movaghar A.
- Evans Rachel
- Khanh Bao Tran Khanh Bao Tran
- Kerin Lourda
- Smyth Nigel
- Tehrani-Banihashemi Arash
- Wright Claire
- Polinder Suzanne
- Webb Tom
- Werring David J
- Omar Temsah
- Johnson T
- Rovira A
- Bowring Angela
- Prakash S.
- Chaiah Y.
- Henok A.
- Asefa NG
- Barker-Collo SL
- Adsuar Jose C.
- Harrington Frances
- Dakin Katy
- Dziewas Rainer
- Oh I. -H.
- Eskandarieh Sharareh
- Bayliss Pauline
- Kim D.
- Sharif Mehdi
- McIlmoyle James
- Oren Eyal
- Hazel Beth
- Sheth Kevin N
- Siddiqi Tariq J
- Finney Kay
- Abraha H. N.
- Gankpe Fortune Gbetoho
- Welch Angela
- Kalani R.
- Macleod Malcolm R.
- Huyen Phuc Do Huyen Phuc Do
- Majeed A.
- Fraser Ruth
- McArdle Damian
- Ewing Jordan
- Hills Robert
- Sheth K. N.
- Mangion David
- Vos Theo
- Campbell Robert
- Bathula Rajaram
- Fereshtehnejad Seyed-Mohammad
- Doyle Clare
- Alam Tahiya
- Lucas Robyn M
- Tintor� Mar
- Quinn N
- Mate KKV
- Nichols E.
- Niranchanan Rangah
- Akseer N
- Ingham Andrea
- Jayaraman S.
- Waugh Dean
- Crowe C. S.
- Mohd Nor Azlisham
- Resnikoff Serge
- Kaul Anil
- Haj-Mirzaian Arya
- Deribe K.
- Quinn Leanne
- Fitzsimmons Paul
- Antonio Carl Abelardo T.
- Gulliver Diane
- Banstola A
- Lami F. H.
- Dandona Rakhi
- Azhar Khalid
- Pillay Julian David
- Rafay Anwar
- Rahimi-Movaghar Afarin
- Smith Simon
- Morse Bethan
- Nichols Emma
- Kumar Pradeep
- Kisa Adnan
- Rajkumar Chakravarthi
- Rafiei A.
- Montalban Xavier
- Brew Helen
- João Pedro Silva
- Ofori-Asenso Richard
- Szoeke Cassandra E I
- Ross Sarah
- Champs AP
- Hussen Mamusha Aman
- Sinha D. N.
- Clive Holmes (237359)
- Vickers Carinna
- Gill S
- Patel Bhavini
- Daryani A.
- Bekele BB
- Sabbagh Parisa
- She J.
- Carrero Juan J
- Williams-Yesson Barbara
- Ronfani Luca
- Jenkins Colin
- Maanoosi Mehran
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- Bennett Derrick A
- Robert Howard (190740)
- Publication venue
- Publication date
- 01/08/2003
- Field of study
No full textFindings from longitudinal and cross-sectional studies suggest an association between high blood pressure and dementia, and in turn the use of antihypertensives has been suggested to reduce incidence of dementia. Alzheimer's disease, the most common cause of dementia, is characterised in part by the deposition of amyloid beta protein (Abeta) in the brain. Reduction of Abeta load is now a major therapeutic strategy. In recent years the renin-angiotensin system, already of recognised importance in the pathogenesis of hypertension, has become a source of interest in the pathogenesis of Alzheimer's disease. This review explores molecular, genetic, and clinical studies that might help explain the relation between the renin-angiotensin system, hypertension, and Alzheimer's disease and whether treatment with angiotensin converting enzyme (ACE) inhibitors and similar treatment strategies have a part to play in the management of the disease
