42,587 research outputs found
Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)
No full textIn an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola
Exercise training protects human and rodent β cells against endoplasmic reticulum stress and apoptosis
No full textProlonged exercise has positive metabolic effects in obese or diabetic individuals. These effects are usually ascribed to improvements in insulin sensitivity. We evaluated whether exercise also generates circulating signals that protect human and rodent β cells against endoplasmic reticulum (ER) stress and apoptosis. For this purpose, we obtained serum from humans or mice before and after an 8 wk training period. Exposure of human islets or mouse or rat β cells to human or rodent sera, respectively, obtained from trained individuals reduced cytokine (IL-1β+IFN-γ)- or chemical ER stressor-induced β-cell ER stress and apoptosis, at least in part via activation of the transcription factor STAT3. These findings indicate that exercise training improves human and rodent β-cell survival under diabetogenic conditions and support lifestyle interventions as a protective approach for both type 1 and 2 diabetes.-Paula, F. M. M. Leite, N. C. Borck, P. C. Freitas-Dias, R. Cnop, M. Chacon-Mikahil, M. P. T. Cavaglieri, C. R. Marchetti, P. Boschero, A. C. Zoppi, C. C. Eizirik, D. L. Exercise training protects human and rodent β cells against endoplasmic reticulum stress and apoptosis.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Estrategias felinas: discurso poetico X midia na poesia brasileira contemporanea : Armando Freitas Filho e Sebastião Uchoa Leite
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e ExpressãoA presente dissertação analisa na produção textual de Armando Freitas Filho e Sebastião Uchoa Leite o conflito entre a mídia, como veiculadora de discursos homogeneizantes na sociedade, e o discurso poético como voz alternativa, marcada pela singularidade e pelo exercício crítico em relação às noções de sujeito, subjetividade, verdade, discurso. Para isso, foram estudadas principalmente obras escritas nos anos 1980
Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′
No full textFirst evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)
Corrigendum to “Presence and function of kisspeptin/KISS1R system in swine ovarian follicles” (Theriogenology (2018) 115 (1–8), (S0093691X1830147X), (10.1016/j.theriogenology.2018.04.006))
No full textThe authors regret the following changes to the author group G. Basinia, F. Grassellia, S. Bussolatia, R. Ciccimarraa, M. Maranesib, A. Bufalarib, C. Dall'Agliob, F. Parilloc,#, M. Zeranib,c,*. a Dipartimento di Scienze Mediche Veterinarie, Università di Parma, 43126 Parma, Italy. b Dipartimento di Medicina Veterinaria, Università di Perugia, 06126 Perugia Italy. c Scuola di Bioscienze e Medicina Veterinaria, Università di Camerino, 62024 Matelica Italy. # Deceased. * Corresponding author: tel.: +39 0755857642; fax +39 0755857654. E-mail address: [email protected] (M. Zerani). And to the acknowledgements and figures
A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging
No full textAuthors Dr. Marisa Benagiano and Prof. Mario Milco D’Elios were not included when this article was originally published. The corrected list of author of this manuscript is: F. Ratto,* S. Centi, C. Avigo, C. Borri, F. Tatini, L. Cavigli, C. Kusmic, B. Lelli, S. Lai, M. Benagiano, M. M. D’Elios, S. Colagrande, F. Faita, L. Menichetti, and R. Pini The affiliation for Dr. Benagiano and Prof. D’Elios is: Department of Experimental and Clinical Medicine University of Florence, Largo Brambilla 3, 50134 Florence, (FI), Italy Ref. [82] was not included in the originally published version of this article. It should be added to the second paragraph on page 7179, which then reads as follows: “More recently, the notion to exploit the natural tropism of cells, such as tumor-associated macrophages,[35–39] T cells,[40,82] mesenchymal stem cells,[41–43] and neural stem cells,[44,45] has begun to emerge as a radical alternative.” Ref. [82] is: G. Baldi, C. Ravagli, M. Comes Franchini, M. M. D’Elios, M. Benagiano, M. Bitossi (Colorobbia Italia S.p.A.) WO 104664, 2015. The Acknowledgements should be corrected to read as follows: “This work was in part supported by the Projects of Tuscan Region “NANOTREAT” and “SYNERGY” and by the ERANET+ Project of Tuscan Region and European Community “LUS BUBBLE”. The authors wish to thank Dr. Daniele Panetta for his expertise in X-ray micro imaging and Dr. Giovanni Baldi of CERICOL Research Center of Colorobbia Group for his expertise and knowledge on cellular nano-engineering.” The authors apologize for any inconvenience or misunderstanding that these errors may have caused. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinhei
Nicotinic acetylcholine receptors in rat forebrain that bind ¹⁸F-nifene: relating PET imaging, autoradiography, and behavior
No full textNicotinic acetylcholine receptors (nAChRs) in the brain are important for cognitive function; however, their specific role in relevant brain regions remains unclear. In this study, we used the novel compound ¹⁸F-nifene to examine the distribution of nAChRs in the rat forebrain, and for individual animals related the results to behavioral performance on an auditory-cognitive task. We first show negligible binding of ¹⁸F-nifene in mice lacking the β2 nAChR subunit, consistent with previous findings that ¹⁸F-nifene binds to α4β2* nAChRs. We then examined the distribution of ¹⁸F-nifene in rat using three methods: in vivo PET, ex vivo PET and autoradiography. Generally, ¹⁸F-nifene labeled forebrain regions known to contain nAChRs, and the three methods produced similar relative binding among regions. Importantly, ¹⁸F-nifene also labeled some white matter (myelinated axon) tracts, most prominently in the temporal subcortical region that contains the auditory thalamocortical pathway. Finally, we related ¹⁸F-nifene binding in several forebrain regions to each animal's performance on an auditory-cued, active avoidance task. The strongest correlations with performance after 14 days training were found for ¹⁸F-nifene binding in the temporal subcortical white matter, subiculum, and medial frontal cortex (correlation coefficients, r > 0.8); there was no correlation with binding in the auditory thalamus or auditory cortex. These findings suggest that individual performance is linked to nicotinic functions in specific brain regions, and further support a role for nAChRs in sensory-cognitive function.Peer reviewedAuthor's Manuscript is also available open access in PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292694.This is the peer reviewed version of the following article: Bieszczad, K. M., Kant, R., Constantinescu, C. C., Pandey, S. K., Kawai, H. D., Metherate, R., Weinberger, N. M. and Mukherjee, J. (2012), Nicotinic acetylcholine receptors in rat forebrain that bind 18F-nifene: Relating PET imaging, autoradiography, and behavior. Synapse, 66: 418–434. doi: 10.1002/syn.21530, which has been published in final form at http://dx.doi.org/10.1002/syn.21530. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving
Titanochrysa trespuntensis Sosa & Freitas
No full textTitanochrysa trespuntensis Sosa & Freitas nov. sp Holotype male, Minas Gerais. Tres Pontas [21 o 25 ’S / 45 o 30 ’W, 900 m], 10.i. 2009, Ferreira C. S Leg. Deposited in the Museum of Zoology, Universidade de São Paulo (MZUSP) São Paulo, Brazil. Measurements. Head: width 1.1 mm. Pronotum: length 0.5 mm, width 0.8 mm. Forewing: length 10.1 mm, width 3.6 mm, length/width ratio = 2.8: 1. Four inner, six outer gradates. Hindwing: length 9.3 mm, width 2.8 mm, length/width ratio = 3.3: 1. Four inner, four outer gradates. Diagnosis. Adults yellowish green, with broad, dark red, longitudinal stripe laterally. Fore- and hindwings without shading on surrounding membrane, gradate veins in parallel series. S 8 + 9 with a protuberance on the apical margin. Microtholi present on S 2–8. Mandibles symmetrical. Description. Head. Vertex smooth, yellowish; occiput without marks (Fig. 13 A); scape pale green, with dark red, longitudinal line laterally not reaching antennal base; pedicel pale green with dorsal black spot laterally; flagellum pale, covered with back bristles, slightly shorter than forewing (Fig. 13 B); frons white; gena black; clypeus white, tinged with black laterally; maxillary, labial palpi black (Fig. 13 C). Mandibles both with prominent basal tooth (Fig. 17 D). FIGURE 14. Titanochrysa trespuntensis Sosa & Freitas sp. nov. Wings. A = anal veins; bsx = basal subcostal crossvein; c.a = costal area; cx = costal crossvein; ig = inner gradates; im = intramedian cell; og = outer gradates; m-cu 2 = second medialcubital crossvein; r-m 1 = first radial crossvein; Rs = radial sector. Thorax. Pale green, with yellow, longitudinal band dorsally; pronotum wider than long, with dark red, longitudinal stripe laterally. Meso- and metanota with red-wine line dorsolaterally (Fig. 13 A). Pleura, sternal areas, legs pale green. Wings (Fig. 14): forewing, hindwing densely covered with black microtrichia apically. Forewing with longitudinal veins dark green; crossveins dark at intersections with longitudinal veins, not infuscate; costal crossveins, radial crossveins, basal subcostal crossvein, inner gradates, outer gradates, m–cu2, 1A, 2 A black. Outer, inner gradates in parallel series, slightly convergent apically. First radial crossvein originating after origin of radial sector, extending approximately to apex of intramedian cell; intramedian cell ovate. Hindwing with longitudinal veins green, black intersections with crossveins; costal crossveins, inner and outer gradates black. Abdomen. Yellowish green dorsally, green laterally, with dark red spots laterally on each tergite. Male terminalia (Fig. 15 A): T 9 +ect elongate basally, tapering at basal margin, covered by stalked setae; dorsal apodeme simple, reaching callus cerci. Sternite S 8 + 9 with a protuberance on the apical margin (Fig. 15 B), numerous setae stemming from thickened bases, ventral apodeme elongate. Male genitalia: gonarcus truncated in dorsal view (Fig. 15 C), slender in lateral view; lateral apodemes shaped like inverted comma, anterior extremity with truncated apex (Fig. 15 D); arcessus short, broad, decurved, trifurcate apically, with field of short setae beneath, dorsal rods parallel, (Fig. 15 C, D); gonosaccus with sparse, thin, scattered gonosetae (Fig. 15 D). Gonapsis expanded anteriorly, with short, acute projection laterally, wide with round, expanded margin apically (Fig. 15 F). Hypandrium internum V-shaped (Fig. 15 G). Female terminalia: S 7 ca. 2.0 times longer than wide, densely covered with medium-sized setae; T 9 +ect with dorsal, ventral margins round; callus cerci round, with ca. 24 trichobothria (Fig. 16 A). Female genitalia: spermatheca (Fig. 16 B–D) pillbox-shaped, spermathecal duct elongate; velum curved laterally; ventral impression shallow. Subgenitale cordate, with elongate medial notch (Fig. 16 E–F). Measurements. Male (n= 2): Head: width 1.2 – 1.2 mm. Pronotum: length 0.5 – 0.5 mm, width 0.9 – 0.9 mm. Forewing: length 10.7–10.8 mm, width 3.7–3.8 mm, length/width ratio = 2.8–2.9: 1. Five inner, five to six outer gradates. Hindwing: length 9.6–9.7 mm, width 2.9 –3.0 mm, length/width ratio = 3.2–3.3: 1. Four inner, four to five outer gradates. Female (n= 2): Head: width 1.– 1.1 mm. Pronotum: length 0.5 – 0.5 mm, width 0.9 – 0.9 mm. Forewing: length 11.0– 11.3 mm, width 3.9 – 3.9 mm, length/width ratio = 2.8–2.9: 1. Five inner, five outer gradates. Hindwing: length 9.6 –10.3 mm, width 2.8–3.1 mm, length/width ratio = 3.3–3.4: 1. Four to five inner, four to five outer gradates. Material examined. Allotype Ƥ: Brazil. Minas Gerais. Tres Pontas [21 o 25 ’S / 45 o 30 ’W, 900 m], 15.xi. 2008, Ferreira C. S Leg (MZUSP); Paratypes: Brazil. Minas Gerais. Tres pontas [21 o 25 ’S / 45 o 30 ’W, 900 m], 13.ix.2008, 13, 1 Ƥ, Ferreira C. S Leg (SFCC); Same, 13.ix.2008, 13, 1 Ƥ, Ferreira C. S Leg (SFCC), head clarified, without abdomen; Same, 20.ix.2008, 13, Ferreira C. S Leg (SFCC); Same, 4.x.2008, 83, 5 ƤƤ, Ferreira C. S Leg (SFCC); Same, 18.x.2008, 13, Ferreira C. S Leg (SFCC); Same, 25.x.2008, 23, 1 Ƥ, Ferreira C. S Leg (SFCC); Same, 10.i.2009, 43, 3 ƤƤ, Ferreira C. S Leg (SFCC); Same, 13.vi.2009, 1Ƥ, Ferreira C. S Leg (SFCC); Same, 11.iv.2009, 13, Ferreira C. S Leg (SFCC); Same, 25.iv.2009, 13, Ferreira C. S Leg (SFCC); Same, 8.viii.2009, 13, 1 Ƥ (UCOB); Same, 6.vii.2009, 13, Ferreira C. S Leg (MIZA); Same, 13.ix.2008, 1Ƥ, Ferreira C. S Leg (MIZA). Etymology. The name refers to the type locality “Tres Pontas, Minas Gerais, Brazil ” Species relationships. Titanochrysa trespuntensis sp. nov. is the only species in the genus with an protuberance on the apical margin of S 8 + 9, wings without black markings on membrane, and wide gonapsis with acute lateral projection. On the male, there are setae beneath the arcessus as in Titanochrysa circumfusa (Burmeister) comb. nov., but T. trespuntensis males do not have X-shaped rods on the arcessus, or striations on the apical surface of the arcessus. Externally, T. trespuntensis resembles some Ungla species, but it can be distinguished from those species because its inner gradates meet the Psm vein and the males have a gonapsis. Geographical distribution. Brazil.Published as part of Sosa, Francisco & Freitas, Sergio De, 2012, A new genus of Neotropical Chrysopini (Neuroptera: Chrysopidae), pp. 1-14 in Zootaxa 3351 on pages 13-17, DOI: 10.5281/zenodo.21066
Ecotoxicological screening of UV-filters using a battery of marine bioassays
No full textThe present study aimed to assess the toxicity of seven UV-filters: zinc oxide nanoparticles (nZnO, particle size <100 nm), titanium dioxide nanoparticles (nTiO2, primary particle size 21 nm), 2-ethylhexyl-4-methoxycinnamate (EHMC), 4-methylbenzylidene camphor (4-MBC), avobenzone (AVO), octocrylene (OCTO) and benzophenone-3 (BP-3) on three species: Aliivibrio fischeri (inhibition of bioluminescence), Phaeodactylum tricornutum (growth inhibition) and Ficopomatus enigmaticus (larval development success). Results showed nTiO2 to be the most toxic for P. tricornutum (EC50 0.043 mg L−1), while no effect was observed in A. fischeri and F. enigmaticus. EHMC was the most toxic to A. fischeri (EC50 0.868 mg L−1 (15 min) and 1.06 mg L−1 (30 min)) and the second most toxic to P. tricornutum. For F. enigmaticus, the lowest percentages of correct development resulted from 4-MBC exposure, with EC50 of 0.836 mg L−1. Overall, AVO induced low toxicity to every assessed species and OCTO was the least toxic for F. enigmaticus larvae. Considering the results obtained for F. enigmaticus, further larval development assays were performed with nZnO and EHMC under different light (light vs darkness) and temperature (20 and 25 °C) conditions, showing higher percentages of correct development at 25 °C, independently on light/darkness conditions. Under different temperature and photoperiod conditions, nZnO was more toxic than EHMC. Overall, nZnO and EHMC were among the most toxic UV filters tested and, when testing the effects of these UV-filters with temperature the results highlight that the impacts are liable to be lessened at higher temperatures (25 °C compared with 20 °C), in the case of this estuarine polychaete species. Nevertheless, further experiments are necessary to describe the effects of these two UV-filters at different organization levels, to study the toxicity of eventual degradation by-products and to provide more information on the combination of different stressors
Chemical oxidation of Eucalyptus benthamii charcoal.
No full textThe aim of this study was to promote the chemical oxidation of Eucalyptus benthamii charcoal, intending the formation of functional groups attached to the charcoal?s condensed aromatic structure.Na publicação: C. M. de Freitas Maia
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