124,869 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pragmatic Case Studies as a Source of Unity in Applied Psychology
No full textTo unify or not to unify applied psychology: that is the question. In this article we review pendulum swings in the historical efforts to answer this question—from a comprehensive, positivist, “top-down,” deductive yes between the 1930s and the early 60s, to a postmodern no since then. A rationale and proposal for a limited, “bottom-up,” inductive yes in applied psychology is then presented, employing a case-based paradigm that integrates both positivist and postmodern themes and components. This paradigm is labeled “pragmatic psychology” and, its specific use of case studies, the “Pragmatic Case Study Method” (“PCS Method”). We call for the creation of peer-reviewed journal-databases of pragmatic case studies as a foundational source of unifying applied knowledge in our discipline. As one example, the potential of the PCS Method for unifying different angles of theoretical regard is illustrated in an area of applied psychology, psychotherapy, via the case of Mrs. B. The article then turns to the broader historical and epistemological arguments for the unifying nature of the PCS Method in both applied and basic psychology.Peer reviewe
Dr. Edwin Wright Collection: Author Unknown
No full textNotes - The author relates several short stories about his neighbours including Alex McDonell, homesteading and life around Meanook and Athabasca (1 page
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Measurement of the ratio of branching fractions B(B0→K∗0γ )/B(B0s→φγ ) and the directCP asymmetry inB 0→K∗0γ
No full textThe ratio of branching fractions of the radiative B decays B0→K⁎0γ and B0s→ϕγ has been measured using an integrated luminosity of 1.0 fb−1 of pp collision data collected by the LHCb experiment at a centre-of-mass energy of s√=7TeV. The value obtained is
B(B0→K⁎0γ)B(B0s→ϕγ)=1.23±0.06(stat.)±0.04(syst.)±0.10(fs/fd),
where the first uncertainty is statistical, the second is the experimental systematic uncertainty and the third is associated with the ratio of fragmentation fractions fs/fd. Using the world average value for B(B0→K⁎0γ), the branching fraction B(B0s→ϕγ) is measured to be (3.5±0.4)×10−5.
The direct CP asymmetry in B0→K⁎0γ decays has also been measured with the same data and found to be
ACP(B0→K⁎0γ)=(0.8±1.7(stat.)±0.9(syst.))%.
Both measurements are the most precise to date and are in agreement with the previous experimental results and theoretical expectations
The construction of Karen Karnak: The multi-author-function
No full textThis thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author
Experimental evaluation of chromatic changes of colored objects under fluorescent lamps and LEDs and perceptual responses
No full textIn the field of electric lighting, the increasing popularity and spread of the LED sources, together with the availability of traditional lamps with different spectral
characteristics, compels the designer to consider in his choices not only aspects related to energy saving, but also to take into account lighting quality, meaning for it a correct and pleasant perception of the surrounding environment. Once fixed the values of illuminance and luminance distributions, the parameters that characterize the sources regarding quality of light, according to European Standard EN 12464-1, and that strongly influence the perception of objects and colors are the color appearance, identified by Correlated Color Temperature (CCT), and Color Rendering Index (CRI). However in presence of sources with similar CCT and CRI but with different Spectral Power Distributions (SPD), different
perceptual effects occur.
In this paper, the effects of two kind of sources, fluorescents and LEDs, both with high CRI, are examined. Results from measurements were analyzed and then put in
relation with results of tests on a significant number of subjects
Branching fraction and CP asymmetry of the decays B+→K0Sπ+ and B+→K0SK+
No full textAn analysis of B+ → K0
Sπ+ and B+ → K0
S K+ decays is performed with the LHCb experiment. The pp
collision data used correspond to integrated luminosities of 1 fb−1 and 2 fb−1 collected at centre-ofmass
energies of
√
s = 7 TeV and
√
s = 8 TeV, respectively. The ratio of branching fractions and the
direct CP asymmetries are measured to be B(B+ → K0
S K+
)/B(B+ → K0
Sπ+
) = 0.064 ± 0.009 (stat.) ±
0.004 (syst.), ACP(B+ → K0
Sπ+
) = −0.022 ± 0.025 (stat.) ± 0.010 (syst.) and ACP(B+ → K0
S K+
) =
−0.21 ± 0.14 (stat.) ± 0.01 (syst.). The data sample taken at
√
s = 7 TeV is used to search for
B+
c
→ K0
S K+ decays and results in the upper limit ( fc · B(B+
c
→ K0
S K+
))/( fu · B(B+ → K0
Sπ+
)) <
5.8 × 10−2 at 90% confidence level, where fc and fu denote the hadronisation fractions of a ¯b
quark
into a B+
c or a B+ meson, respectively
Proteomics to investigate the molecular bases of Nasu-Hakola Disease
No full text1. Purpose.
Nasu-Hakola disease (NHD), also known as Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy (PLOSL), is a recessively inherited rare systemic disorder characterized by simultaneous impairment of nervous and skeletal systems. The genetic bases of NHD have been related to a structural defect of two genes (DAP12 and TREM2) encoding for different subunits of the membrane receptor signaling complex, expressed by cells of both systems involved [1]. To date, molecular or proteomic studies about this disorder are scarce, and only case reports have been reported. Being the molecular analysis mandatory for obtaining insights into the mechanisms of the disease, aim of the present study was the development of an optimal proteomic approach to characterize the proteome of Lymphoblastoid cells from PLOSL patients.
2. Materials.
Two NHD patients with a novel mutation in exon 2 of the TREM2 gene (NHD); four healthy carriers (HC) and two healthy subjects (HS) belonging to the same Italian family were submitted to blood withdrawal to isolate and immortalize the B-Lymphocytes used for this research [2].
3. Methods.
About 30x106 B-Lymphocytes were recovered from plasma samples and immortalized. Proteins from each sample were treated with a MS compatible detergent, digested by trypsin and analyzed using a gel-free proteomic approach (Multidimensional Protein Identification Technology, MudPIT), according to conditions previously reported [3]. Finally, data handling was performed using the 3.3.1 Bioworks and MAProMa softwares.
4. Results.
MudPIT analysis allowed the identification of more than 3000 distinct proteins. The comparison of protein profiles from NHD; HC and HS groups by means of MAProMa showed that, while the three groups shared more than 50% of proteins, only 10% were peculiar of each category. Of note, the proteins differentially expressed among groups were in agreement with those previously characterized by applying a two-dimensional gel electrophoresis (2-DE) approach[2]. Identification of these proteins allowed to confirm that also NHD onset may involve the glucose pathway, as suggested for other neurodegenerative disorders.
5. Discussion & Conclusion.
Application of MudPIT proteomics analysis to Lymphoblastoid cells of individuals investigated in this study allowed to characterize a number of proteins about 100-fold higher than those identified by 2-DE [2] and to highlight proteins associated to other neurodegenerative processes. Given the absence of reports dealing with the application of shotgun proteomics to NHD investigation, this work represents a proof of principle in this field. In fact, an extensive protein profile of Lymphoblastoid cells from NHD subjects has been obtained that will be useful to characterize metabolic pathways involved in functional alterations of this pathology
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