13 research outputs found
Fortalecimiento de la competencia uso comprensivo del conocimiento científico a partir de una secuencia didáctica de estequiometría basada en la estrategia: Aprendizaje basado en problemas, y el uso del simulador PhET en estudiantes de grado décimo de la IED La Gaitana en la localidad de Suba Bogotá, Colombia.
No full textEste proyecto tiene como objeto implementar
estrategias pedagógicas exitosas en la clase de ciencias que fortalezcan conceptos y habilidades
científicas frente a la competencia evaluada en el ICFES “Uso comprensivo del conocimiento
científico” a partir de la enseñanza de la estequiometría en estudiantes de grado décimo.MaestríaMagíster en Recursos Digitales Aplicados a la Educació
Author Correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.
No full textCorrection to: Nature Human Behaviour https://doi.org/10.1038/s41562-021-01173-x, published online 2 August 2021.In the version of this article initially published, the following authors were omitted from the author list and the Author contributionssection for “investigation” and “writing and editing”: Nandor Hajdu (Institute of Psychology, ELTE Eötvös Loránd University, Budapest,Hungary), Jordane Boudesseul (Facultad de Psicología, Instituto de Investigación Científica, Universidad de Lima, Lima, Perú), RafałMuda (Faculty of Economics, Maria Curie-Sklodowska University, Lublin, Poland) and Sandersan Onie (Black Dog Institute, UNSWSydney, Sydney, Australia & Emotional Health for All Foundation, Jakarta, Indonesia). In addition, Saeideh FatahModares’ name wasoriginally misspelled as Saiedeh FatahModarres in the author list. Further, affiliations have been corrected for Maria Terskova (NationalResearch University Higher School of Economics, Moscow, Russia), Susana Ruiz Fernandez (FOM University of Applied Sciences,Essen; Leibniz-Institut fur Wissensmedien, Tubingen, and LEAD Research Network, Eberhard Karls University, Tubingen, Germany),Hendrik Godbersen (FOM University of Applied Sciences, Essen, Germany), Gulnaz Anjum (Department of Psychology, Simon FraserUniversity, Burnaby, Canada, and Department of Economics & Social Sciences, Institute of Business Administration, Karachi, Pakistan).<br/
Helena Kolody, carbono & diamante: uma biografia ilustrada
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em LiteraturaHelena Kolody, carbono & diamante - uma biografia ilustrada conta a vida da escritora Helena Kolody, a partir de sua inscrição na literatura, questionando sua identidade, o mundo que a cercava e o sentido de sua existência. Equivale a dizer: em sua lírica, reflexões e sentimentos se entretecem a partir de uma matéria pessoal e localizada. Da estação ferroviária à estação tubo; da Ucrânia ao centro de Curitiba; de Paisagem interior a Reika; do século XIX ao século XXI, a literatura de Helena Kolody gerencia sua presença na consolidação do binômio arte-vida. O retrato da autora acaba se constituindo também por meio de farto aparato iconográfico; pelos mais de quinhentos textos críticos elencados e por sua obra completa. Fragmentação deliberadamente assumida, a pessoa se revela em sua inteireza.Helena Kolody, carbon & diamond - an illustrated biography tells the life of Helena Kolody, from her very insertion in literature, as it questions her identity, the world surrounding her, and the meaning of her existence. That is equivalent to saying that in her poetry there is the intermingling of reflections and feelings that derive from personal and localized material. From the railroad station to the tube-shaped bus stops; from Ukraine to downtown Curitiba; from Paisagem interior to Reika; from the nineteenth century to the twenty-first century, Helena Kolody's literature guarantees her presence in the consolidation of the art/life binomial. The portrait of the author ends up by also being made up of an abundant iconographic apparatus, of the over five hundred critical texts listed, and of her complete work. The person, although deliberately accepting her own fragmentation, reveals herself in her entireness
Author Correction : Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
No full textGenetic discoveries of Alzheimer's disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer's disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer's disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer's disease
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
No full textAn amendment to this paper has been published and can be accessed via a link at the top of the paper
Author Correction: Genetic meta-analysis of diagnosed Alzheimer\u27s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
No full textAn amendment to this paper has been published and can be accessed via a link at the top of the paper
Baldomero Sanín Cano (1861-1957). From Rionegro to Bogotá: a journey to the encounter with intellectual cosmopolitism
No full textEste trabajo, inscrito en la línea de la Historia Intelectual y con un enfoque biográfico, reconstruye la trayectoria vital e intelectual de Baldomero Sanín Cano (1861-1957) desde sus inicios hasta su viaje hacia el extranjero en 1909. A partir de la teoría de los rituales de interacción de Randal Collins, se sigue de cerca su recorrido formativo y se rastrean las redes sociales e intelectuales a las que el autor se adscribe. Con apoyo en el relevo generacional propuesto por Karl Mannheim, se identifican los temas en debate y las posturas que el personaje, enmarcado en su generación, asume a lo largo del último tercio del siglo XIX en medio del agitado ambiente político, económico y cultural de una nación apenas en proceso de consolidación. En cuanto al intelectual, su definición y función social, se acogen las ideas de Carlos Altamirano y Mannheim. El concepto de nación y su dinámica se entiende en términos de “comunidad imaginada” de Benedict Anderson, “ciudad letrada”, de Ángel Rama y “ciudad burguesa”, de José Luis Romero. Lo biográfico se orienta desde François Dosse y Gilberto Loaiza Cano, principalmente. La prensa es la mayor fuente primaria, pero se aprovecha todo tipo de documentos. La investigación esclarece aspectos como el origen familiar del personaje, su formación temprana y sus incursiones iniciales en la vida intelectual. Identifica puntos de crisis y giros clave en el trazado de las ideas del autor antioqueño quien, en clara discrepancia con el hispanoamericanismo impuesto por el gobierno de la Regeneración, se decanta por caminos que desembocan en el modernismo artístico, literario, y en parte, el político, pues con ese criterio participó en el gobierno del General Rafael Reyes. Adicionalmente, se rescatan varios artículos desconocidos del autor, ampliándose así la base de análisis para futuros estudios de su obra. (Texto tomado de la fuente)This work, inscribed in the line of Intellectual History and with a biographical approach, reconstructs the vital and intellectual trajectory of Baldomero Sanín Cano (1861-1957) from his beginnings until his trip abroad in 1909. Based on the theory of Randal Collins' interaction rituals, his formative journey is closely followed and the social and intellectual networks to which the author belongs are traced. With support in the generational change proposed by Karl Mannheim, the topics under debate and the positions that the character, framed in his generation, assumes throughout the last third of the 19th century in the midst of the hectic political, economic and cultural environment of a nation just in the process of consolidation. Regarding the intellectual, its definition and social function, the ideas of Carlos Altamirano and Mannheim are accepted. The concept of nation and its dynamics is understood in terms of “imagined community” by Benedict Anderson, “lettered city” by Ángel Rama and “bourgeois city” by José Luis Romero. The biographical aspect is mainly guided by François Dosse and Gilberto Loaiza Cano. The press is the largest primary source, but all types of documents are used. The investigation clarifies aspects such as the family origin of the character, his early training and his initial forays into intellectual life. It identifies points of crisis and key turns in the outline of the ideas of the Antioquian author who, in clear disagreement with the Hispano-Americanism imposed by the Regeneration government, opts for paths that lead to artistic, literary modernism, and in part, the political, since with that criterion he participated in the government of General Rafael Reyes. Additionally, several unknown articles by the author are rescued, thus expanding the analysis base for future studies of his work.ColcienciasDoctoradoDoctor en Ciencias Humanas y SocialesHisoria IntelectualÁrea Curricular de Ciencias Humanas y Sociale
Baldomero Sanín Cano (1861-1957). From Rionegro to Bogotá: a journey to the encounter with intellectual cosmopolitism
No full textEste trabajo, inscrito en la línea de la Historia Intelectual y con un enfoque biográfico, reconstruye la trayectoria vital e intelectual de Baldomero Sanín Cano (1861-1957) desde sus inicios hasta su viaje hacia el extranjero en 1909. A partir de la teoría de los rituales de interacción de Randal Collins, se sigue de cerca su recorrido formativo y se rastrean las redes sociales e intelectuales a las que el autor se adscribe. Con apoyo en el relevo generacional propuesto por Karl Mannheim, se identifican los temas en debate y las posturas que el personaje, enmarcado en su generación, asume a lo largo del último tercio del siglo XIX en medio del agitado ambiente político, económico y cultural de una nación apenas en proceso de consolidación. En cuanto al intelectual, su definición y función social, se acogen las ideas de Carlos Altamirano y Mannheim. El concepto de nación y su dinámica se entiende en términos de “comunidad imaginada” de Benedict Anderson, “ciudad letrada”, de Ángel Rama y “ciudad burguesa”, de José Luis Romero. Lo biográfico se orienta desde François Dosse y Gilberto Loaiza Cano, principalmente. La prensa es la mayor fuente primaria, pero se aprovecha todo tipo de documentos. La investigación esclarece aspectos como el origen familiar del personaje, su formación temprana y sus incursiones iniciales en la vida intelectual. Identifica puntos de crisis y giros clave en el trazado de las ideas del autor antioqueño quien, en clara discrepancia con el hispanoamericanismo impuesto por el gobierno de la Regeneración, se decanta por caminos que desembocan en el modernismo artístico, literario, y en parte, el político, pues con ese criterio participó en el gobierno del General Rafael Reyes. Adicionalmente, se rescatan varios artículos desconocidos del autor, ampliándose así la base de análisis para futuros estudios de su obra. (Texto tomado de la fuente)This work, inscribed in the line of Intellectual History and with a biographical approach, reconstructs the vital and intellectual trajectory of Baldomero Sanín Cano (1861-1957) from his beginnings until his trip abroad in 1909. Based on the theory of Randal Collins' interaction rituals, his formative journey is closely followed and the social and intellectual networks to which the author belongs are traced. With support in the generational change proposed by Karl Mannheim, the topics under debate and the positions that the character, framed in his generation, assumes throughout the last third of the 19th century in the midst of the hectic political, economic and cultural environment of a nation just in the process of consolidation. Regarding the intellectual, its definition and social function, the ideas of Carlos Altamirano and Mannheim are accepted. The concept of nation and its dynamics is understood in terms of “imagined community” by Benedict Anderson, “lettered city” by Ángel Rama and “bourgeois city” by José Luis Romero. The biographical aspect is mainly guided by François Dosse and Gilberto Loaiza Cano. The press is the largest primary source, but all types of documents are used. The investigation clarifies aspects such as the family origin of the character, his early training and his initial forays into intellectual life. It identifies points of crisis and key turns in the outline of the ideas of the Antioquian author who, in clear disagreement with the Hispano-Americanism imposed by the Regeneration government, opts for paths that lead to artistic, literary modernism, and in part, the political, since with that criterion he participated in the government of General Rafael Reyes. Additionally, several unknown articles by the author are rescued, thus expanding the analysis base for future studies of his work.ColcienciasDoctoradoDoctor en Ciencias Humanas y SocialesHisoria IntelectualÁrea Curricular de Ciencias Humanas y Sociale
Risk factors for bloodstream infections due to carbapenem-resistant Enterobacterales: a nested case-control-control study
No full textBackground: Carbapenem-resistant Enterobacterales (CRE) bloodstream infections (BSIs) are a major threat to patients. To date, data on risk factors have been limited, with low internal and external validity. In this multicentre study, risk factors for CRE BSI were determined by comparison with two control groups: patients with carbapenem-susceptible Enterobacterales (CSE) BSI, and patients without Enterobacterales infection (uninfected patients). Methods: A multicentre, case-control-control study was nested in a European prospective cohort study on CRE (EURECA). CRE BSI:CSE BSI matching was 1:1, CRE BSI:Uninfected patients matching was 1:3, based on hospital, ward and length of stay. Conditional logistic regression was applied. Results: From March 2016 to November 2018, 73 CRE BSIs, 73 CSE BSIs and 219 uninfected patients were included from 18 European hospitals. For CRE versus CSE BSI, previous CRE colonization/infection [incidence rate ratio (IRR) 7.32; 95% CI 1.65-32.38) increased the risk. For CRE versus uninfected controls, independent risk factors included: older age (IRR 1.03; 95% CI 1.01-1.06), patient referral (long-term care facility: IRR 7.19; 95% CI 1.51-34.24; acute care hospital: IRR 5.26; 95% CI 1.61-17.11), previous colonization/infection with other MDR organisms (MDROs) (IRR 9.71; 95% CI 2.33-40.56), haemodialysis (IRR 8.59; 95% CI 1.82-40.53), invasive procedures (IRR 5.66; 95% CI 2.11-15.16), and β-lactam/β-lactamase inhibitor combinations (IRR 3.92; 95% CI 1.68-9.13) or third/fourth generation cephalosporin (IRR 2.75; 95% CI 1.06-7.11) exposure within 3 months before enrolment. Conclusions: Evidence of previous CRE colonization/infection was a major risk factor for carbapenem resistance among Enterobacterales BSI. Compared with uninfected patients, evidence of previous MDRO colonization/infection and healthcare exposure were important risk factors for CRE BSI. Targeted screening, infection prevention and antimicrobial stewardship should focus on these high-risk patients. © 2024 The Author(s). Published by Oxford University Press on behalf of British Society for Antimicrobial Chemotherapy
