176,833 research outputs found

    Vitamin D receptor (VDR) polymorphisms are associated to spontaneous preterm birth and maternal aspects

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    Preterm birth (PTB) is featured by less than 37 weeks of gestational age or fewer than 259 days since the first day from the last menstrual period. Complications of PTB are the major cause of neonatal deaths, several factors are linked to PTB increased risk including immunological and genetics. Vitamin D plays an important role in immune response modulation and its action occurs through the vitamin D receptor (VDR), which recently has been described as overexpressed in human placenta during the pregnancy. Herein we assessed two single nucleotide polymorphisms (SNPs) FokI (rs2228570 A>G) and Cdx-2 (rs11568820 T>C), within VDR, using TaqMan fluorogenic probes, and differential susceptibility to SPTB. We assessed 104 pregnant women with SPTB and 85 women with normal birth in a Northeastern Brazilian population. Statistically significant differences for both SNPs where found when comparing allele and genotype frequencies in both groups: the T allele for rs2228570 and A allele for rs11568820 were significantly more frequent in SPTB group than in normal birth group (p=0.000013 and p=0.00466, respectively). The rs11568820 A/A genotype was associated to clinical/demographic variables such as: premature birth (p=0.007), neonate weight (p=0.039), presence of infection during pregnancy (p=0.011) and premature birth among multiparous (p=0.015). The rs2228570 T/T genotype associated with gestational diabetes mellitus (p=0.044) and chorioamnionitis during pregnancy (p=0.043). In conclusion our findings indicate an association between polymorphisms FokI and Cdx-2 within VDR gene and SPTB, suggesting their involvement in the triggering of these syndrome

    Obras poeticas de Manoel Ignacio da Silva Alvarenga, (Alcindo Palmireno)

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    Silva Alvarenga foi uma das figuras mais importantes da poesia brasileira do Arcadismo. Sua obra tem caráter nacionalista, exalta a natureza e propõe um modelo de poesia lírica de sabor quase popular. É considerado o precursor do Romantismo no Brasil. Esta obra, em dois volumes, contém juízos críticos de Simonde de Sismondi, Adrien Balbi, Januario da Cunha Barbosa, J. M. da Costa e Silva, J. M. Pereira da Silva e J. C. Fernandes Pinheiro, biografia de Silva Alvarenga e noticia sobre suas obras, além dos autos da devassa sofrida pelo autor, quando esteve preso a mando do Vice-Rei, Conde de Resende, sob a acusação de conspirar contra a Coroa Portuguesa e a Igreja Católica.Collegidas, annotadas e precedidas do juizo critico dos escriptores nacionaes e estrangeiros e de uma noticia sobre o auctor e suas obras e acompanhadas de documentos historicos por J. Norberto de Souza S

    Prompt charm production in pp collisions at &#8730;<span style="text-decoration:overline">s</span>=7 TeV

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    Charm production at the LHC in pp collisions at s√=7 TeV is studied with the LHCb detector. The decays D0→K−π+, D+→K−π+π+, D⁎+→D0(K−π+)π+, D+s→ϕ(K−K+)π+, Λ+c→pK−π+, and their charge conjugates are analysed in a data set corresponding to an integrated luminosity of 15 nb−1. Differential cross-sections dσ/dpT are measured for prompt production of the five charmed hadron species in bins of transverse momentum and rapidity in the region 0&#60;pT&#60;8 GeV/c and 2.0&#60;y&#60;4.5. Theoretical predictions are compared to the measured differential cross-sections. The integrated cross-sections of the charm hadrons are computed in the above pT-y range, and their ratios are reported. A combination of the five integrated cross-section measurements gives σ(cc¯)pT&#60;8 GeV/c,2.0&#60;y&#60;4.5=1419±12(stat)±116(syst)±65(frag) μb, where the uncertainties are statistical, systematic, and due to the fragmentation functions

    Edessa (Edessa) lewisi Fernandes & Silva 2015

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    Edessa (E.) lewisi Fernandes & Silva, 2015 (Figs. 13, 27 C,D, 32 A,B) Edessa lewisi Fernandes et al., 2015: 515. Holotype and paratypes: see Fernandes et al. (2015). Complementary description. The humeral angle brown spot expanding into the pronotum in dorsal and ventral views (Fig. 27 C,D). Ventral surface. Dark stripe of the propleuron covering 2/3 of the width of the sclerite (Fig. 27 D). Abdomen with spine of third segment acuminated (Fig. 13 G). Intersegmental brown areas wide, not reaching lateral margin (Fig. 27 D). Median longitudinal brown band complete, suffused (Fig. 27 D). Male genitalia, dorsal side of the pygophore with a suffused brown area occupying 1/3 of the surface (Fig. 13 A,B). Comments. The original description and comments were presented in Fernandes et al. (2015). Here we present photographs of the holotype in dorsal and ventral views. Also, a plate with photographs of the male and female external genitalia, because the original description presents only hand-drawn drawings. See comments of E. (E.) bella. Distribution (Fig. 32 A,B): See Fernandes et al. (2015).Published as part of Mendonça, Maria Thayane Da Silva, Silva, Valéria Juliete Da & Fernandes, José Antônio Marin, 2023, Diagnose of the nominal subgenus of Edessa and description of the E. sexdens group (Heteroptera, Pentatomidae, Edessinae), pp. 1-63 in Zootaxa 5240 (1) on page 33, DOI: 10.11646/zootaxa.5240.1.1, http://zenodo.org/record/763954

    Search for the decay Bs0→D*∓π±

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    A search for the decay Bs0→D*∓π± is presented using a data sample corresponding to an integrated luminosity of 1.0  fb-1 of pp collisions collected by LHCb. This decay is expected to be mediated by a W-exchange diagram, with little contribution from rescattering processes, and therefore a measurement of the branching fraction will help us to understand the mechanism behind related decays such as Bs0→π+π- and Bs0→DD̅ . Systematic uncertainties are minimized by using B0→D*∓π± as a normalization channel. We find no evidence for a signal, and set an upper limit on the branching fraction of B(Bs0→D*∓π±)&#60;6.1(7.8)×10-6 at 90% (95%) confidence level

    Enna trivittata Silva & Lise 2009

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    Enna trivittata Silva & Lise, 2009 Enna trivittata Silva & Lise, 2009 b: 49, figs 1, 5– 7, female holotype from Fazenda Santa Maria do Meio, São Pedro, São Paulo, Brazil [22 ° 33 ’S, 47 ° 57 ’W], 29.V. 2001, R. M. C. Castro (IBSP 57336) (examined). New record. PERU, Madre de Dios: 15 km E from Puerto Maldonado [12 ° 33 ’S, 69 °03’W], elevation 200m, 1 Ƥ, 19.VII. 1989, D. Silva (MUSM 50055). Distribution. Peru and Brazil.Published as part of Cruz, Estevam L., Silva, Da, Viquez, Carlos & Lise, Arno A., 2012, On the Neotropical spider genera Enna O. Pickard-Cambridge, 1897 and Syntrechalea F. O. Pickard-Cambridge, 1902 (Araneae, Lycosoidea, Trechaleidae): descriptions, taxonomic notes and new records, pp. 55-62 in Zootaxa 3334 on page 60, DOI: 10.5281/zenodo.28129

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.

    Letter from C. D. Dawson, Tusayan Copper Mining and Smelting, to Carl Hayden

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    Letter from C. D. Dawson to Carl Hayden urging him to consider the rights of miners and farmers when drawing up the boundaries for the proposed park

    Enna igarape Silva, Lise & Carico 2008

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    Enna igarape Silva, Lise & Carico, 2008 Enna igarape Silva et al. 2008: 96, figs 5, 97– 111, male holotype from Igarapé da Lontra, Rio Urucú, Porto Urucú, Coari, Amazonas, Brazil [04° 21 ’S, 49 ° 32 ’W], 23.VII. 2003, D. D. Guimarães (MPEG 1435) (examined). New record. PERU, San Martin: Moyobamba, Yuracyacu [05° 54 ’ 6.42 ’’S, 77 ° 11 ’ 18.92 ’’W], elevation 816m, 1 Ƥ, 11.IX. 2008, W. Paredes & C. Albujar (MUSM). Distribution. Peru and Brazil.Published as part of Cruz, Estevam L., Silva, Da, Viquez, Carlos & Lise, Arno A., 2012, On the Neotropical spider genera Enna O. Pickard-Cambridge, 1897 and Syntrechalea F. O. Pickard-Cambridge, 1902 (Araneae, Lycosoidea, Trechaleidae): descriptions, taxonomic notes and new records, pp. 55-62 in Zootaxa 3334 on page 60, DOI: 10.5281/zenodo.28129

    FIGURE 3. A-B. Hohenbergia reconcavensis. C–D. H. stellata. E–F. H. ituberaensis. A, C, E. Plant with inflorescence. B, D, F in Hohenbergia amargosensis (Bromeliaceae: Bromelioideae), a new ornamental species from Bahia, Brazil

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    FIGURE 3. A-B. Hohenbergia reconcavensis. C–D. H. stellata. E–F. H. ituberaensis. A, C, E. Plant with inflorescence. B, D, F. Details of the Inflorescences. Photos: A–B. E.Leme, C–F. E.H.SouzaPublished as part of Souza, Everton Hilo De, Silva, Tiago Abreu Da, Aona, Lidyanne Y. S., Souza, Fernanda V. D. & Leme, Elton M. C., 2022, Hohenbergia amargosensis (Bromeliaceae: Bromelioideae), a new ornamental species from Bahia, Brazil, pp. 86-92 in Phytotaxa 567 (1) on page 90, DOI: 10.11646/phytotaxa.567.1.8, http://zenodo.org/record/713805
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