129 research outputs found
Large-scale DAQ tests for the LHCb upgrade
No full textThe Data Acquisition (DAQ) of the LHCb experiment[1] will be upgraded in 2020 to a high-bandwidth trigger-less readout system. In the new DAQ event fragments will be forwarded to the to the Event Builder (EB) computing farm at 40 MHz. Therefore the front-end boards will be connected directly to the EB farm through optical links and PCI Express based interface cards. The EB is requested to provide a total network capacity of 32Tb/s, exploiting about 500 nodes. In order to get the required network capacity we are testing various technology and network protocols on large scale clusters. We developed on this purpose an Event Builder implementation designed for an InfiniBand interconnect infrastructure. We present the results of the measurements performed to evaluate throughput and scalability measurements on HPC scale facilities
Salida de campo a La Tour du Valat y La Capeliére (La Camarga, Francia) el 21 de mayo de 1954
No full textSalida de campo a La Tour du Valat y La Capeliére (La Camarga, Francia) el 21 de mayo de 1954, de la que se anotaron observaciones sobre ranas, los siguientes peces: Anguilla anguilla (Anguila), "Carp. sol", Cyprinus carpio (Carpa) y Gambusia holbrooki (Gambusia), el reptil Natrix natrix (Culebra de collar, llamada Tropidonotus natrix por el autor), los siguientes mamíferos: Mus spicilegus (Ratón), Mustela nivalis (Comadreja) y Rattus norvegicus (Rata parda, llamada E.norvegicus por el autor), y las siguientes aves: Acrocephalus arundinaceus (Carricero tordal), Acrocephalus scirpaceus (Carricero común), Alauda arvensis (Alondra común), Anas platyrhynchos (Ánade azulón, también llamado Pato bravío por el autor), Anas strepera (Ánade friso), Apus sp. (Vencejo), Ardea purpurea (Garza imperial), Botaurus stellaris (Avetoro común), Burhinus oedicnemus (Alcaraván común), Carduelis sp. (seguramente, el Jilguero, C.carduelis), Chlidonias hybrida (Fumarel cariblanco), Circus aeruginosus (Aguilucho lagunero occidental), Corvus monedula (Grajilla, llamada Coloeus por el autor), Cuculus canorus (Cuco común), Delichon urbica (Avión común, llamado Chelidon urbica por el autor), Egretta garzetta (Garceta común), Emberiza schoeniclus (Escribano palustre), Falco biarmicus (Halcón Borni), Falco peregrinus (Halcón peregrino, también llamado Alcotán palomero), Falco tinnunculus (Cernícalo vulgar), Fulica sp. (Focha), Galerida cristata (Cogujada común), Glareola pratincola (Canastera común), Himantopus himantopus (Cigüeñuela común), Hirundo sp. (Golondrina), Ixobrychus minutus (Avetorillo común), Lanius senator (Alcaudón común), Larus argentatus (Gaviota argéntea), Larus ridibundus (Gaviota reidora), Locustella luscinioides (Buscarla unicolor), Luscinia megarhynchos (Ruiseñor común), Luscinia sp. (Ruiseñor o Pechiazul), "Lusciniola", Merops apiaster (Abejaruco europeo), Miliaria calandra (Triguero, llamada Emberiza calandra por el autor), Motacilla flava (Lavandera boyera), Netta rufina (Pato colorado), Nycticorax nycticorax (Martinete común), Oenanthe oenanthe (Collalba gris), Parus major (Carbonero común, también conocido como Chapin), Passer domesticus (Gorrión domestico), Perdiz (Alectoris sp. o Perdix sp.), Phoenicurus ochruros (Colirrojo tizón), Phylloscopus bonelli (Mosquitero papialbo), Pica pica (Urraca, llamada "marica" y "picarza" por el autor), Picus viridis (Pito real), Porzana parva (Polluela bastarda), Rallus aquaticus (Rascón europeo), Riparia riparia (Avión zapador), Saxicola rubetra (Tarabilla norteña), Sterna sp. (Charrán), Sternula sp., Streptopelia sp. (Tórtola), Sylvia atricapilla (Curruca capirotada), Sylvia communis (Curruca zarcera), Sylvia conspicillata (Curruca tomillera), Upupa epops (Abubilla, también llamada Bubillo por el autor) y Vanellus vanellus (Avefría europea). Incluye un taxiado de aves y datos de contenidos estomacales.Field trip to La Tour du Valat and La Capeliére (The Camargue, France) the 21st of May of 1954, of which there were noted observations about frogs, the following fishes: Anguilla anguilla (European Eel), "Carp. sol", Cyprinus carpio (Common Carp) and Gambusia holbrooki (Eastern Mosquitofish), the reptil Natrix natrix (Grass Snake, refered as Tropidonotus natrix by the author), the following mammals: Mus spicilegus (Mound-Building Mouse), Mustela nivalis (Least Weasel) and Rattus norvegicus (Brown Rat, refered as E.norvegicus by the author), and the following birds: Acrocephalus arundinaceus (Great Reed-warbler), Acrocephalus scirpaceus (Reed Warbler), Alauda arvensis (Eurasian Skylark), Anas platyrhynchos (Mallard), Anas strepera (Gadwall), Apus sp. (Swift), Ardea purpurea (Purple Heron), Botaurus stellaris (Great Bittern), Burhinus oedicnemus (Eurasian Thick-Knee), Carduelis cannabina (Pardillo común, llamada Colorín y Acanthis cannabina por el autor), Carduelis sp. (probably, the European Goldfinch, C.carduelis), Chlidonias hybrida (Whiskered Tern), Circus aeruginosus (Western Marsh-Harrier), Corvus monedula (Eurasian Jackdaw, refered as Coloeus by the author), Cuculus canorus (Common Cuckoo), Delichon urbica (House Martin, refered as Chelidon urbica by the author), Egretta garzetta (Little Egret), Emberiza schoeniclus (Reed Bunting), Falco biarmicus (Lanner Falcon), Falco peregrinus (Peregrine Falcon), Falco tinnunculus (Common Kestrel), Fulica sp. (Coot), Galerida cristata (Crested Lark), Glareola pratincola (Collared Pratincole), Himantopus himantopus (Black-winged Stilt), Hirundo sp. (Swallow), Ixobrychus minutus (Little Bittern), Lanius senator (Woodchat Shrike), Larus argentatus (Herring Gull), Larus ridibundus (Common Black-headed Gull), Locustella luscinioides (Savi´s Warbler), Luscinia megarhynchos (Common Nightingale) Luscinia sp. (Nightingale or Bluethroat), "Lusciniola", Merops apiaster (European Bee-eater), Miliaria calandra (Corn Bunting, refered as Emberiza calandra by the author), Motacilla flava (Yellow Wagtail), Netta rufina (Red-crested Pochard), Nycticorax nycticorax (Black-crowned Night Heron), Oenanthe oenanthe (Northern Wheatear), Partridge (Alectoris sp. or Perdix sp.), Parus major (Great Tit), Passer domesticus (House Sparrow), Phoenicurus ochruros (Black Redstart), Phylloscopus collybita (Common Chiffchaff), Pica pica (Black-billed Magpie), Picus viridis (Eurasian Green Woodpecker), Porzana parva (Little Crake), Rallus aquaticus (Water Rail), Riparia riparia (Sand Martin), Saxicola rubetra (Whinchat), Sterna sp. (Tern), Sternula sp., Streptopelia sp. (Turtle-dove), Sylvia atricapilla (Blackcap), Sylvia communis (Common Whitethroat), Sylvia conspicillata (Spectacled Warbler), Upupa epops (Eurasian Hoopoe) and Vanellus vanellus (Northern Lapwing). A birds census and data from stomach contents are included
Salida de campo por La Camarga (Provenza, Francia) el 12 de mayo de 1954
No full textSalida de campo por la reserva natural de La Camarga (Provenza, Francia), recorriendo Le Sambuc, La Tour du Valat, Villaneuve y La Capeliére, el 12 de mayo de 1954, de la que se anotaron observaciones sobre el pez Gambusia holbrooki (Gambusia), el reptil Rhinechis scalaris (Culebra de escalera, llamada Elaphe scalaris o Coluber scalaris por el autor), y las siguientes aves: Anas platyrhynchos (Ánade azulón, también llamado Pato bravío por el autor), Ardea sp. (Garza), Corvus monedula (Grajilla, llamada Coloeus por el autor), Cuculus canorus (Cuco común) , Egretta garzetta (Garceta común), Hippolais sp. (Zarcero), Lanius senator (Alcaudón común), Larus ridibundus (Gaviota reidora), Miliaria calandra (Triguero, llamada Emberiza calandra por el autor), Pica pica (Urraca, llamada "marica" y "picarza" por el autor) y Porzana porzana (Polluela pintoja).Field trip through the nature reserve of The Camargue (Provenza, Francia), travelling through Le Sambuc, La Tour du Valat, Villaneuve and La Capeliére, the 12th of May of 1954, of which there were noted observations about the fish Gambusia holbrooki (Eastern Mosquitofish), the reptil Rhinechis scalaris (Ladder Snake, refered as Elaphe scalaris by the author), and the following birds: Anas platyrhynchos (Mallard), Ardea sp. (Heron), Corvus monedula (Eurasian Jackdaw, refered as Coloeus by the author), Cuculus canorus (Common Cuckoo), Egretta garzetta (Little Egret), Hippolais sp. (Warbler), Lanius senator (Woodchat Shrike), Larus ridibundus (Common Black-headed Gull), Miliaria calandra (Corn Bunting, refered as Emberiza calandra by the author), Pica pica (Black-billed Magpie) and Porzana porzana (Spotted Crake)
Current status of the Dalmatian pelican and the great white pelican populations of the Black Sea/Mediterranean flyway
No full textThe Dalmatian pelican (DP) Pelecanus crispus and the great white pelican (GWP) Pelecanus onocrotalus are listed as 'Vulnerable' and 'Least Concern', respectively, in the IUCN Red List. We present an updated estimation of the Black Sea/Mediterranean flyway population status of both species, based on data provided by experts working in all 7 countries of the region where pelicans breed and/or overwinter, who came together at the 1st Workshop on Pelican Research and Conservation in Prespa, Greece. The DP breeding population in the Black Sea and Mediterranean countries increased from 1730-2105 pairs in the years 2000-2010 to 2154-2437 pairs in 2011-2012. Approximately 40% of the Palaearctic breeding population of GWP occurred in Southeast Europe and Turkey. In 2011-2012 the GWP population in this region was estimated to be 4702-5175 pairs, and has remained more or less stable during the last decade. Although all the breeding sites for both species are in protected areas, disturbance at nesting places was considered to be the main threat. Direct persecution and electric power lines still cause occasional problems. In deltaic lagoons, erosion and inundation of nesting sites cause breeding failures in DPs, while in inland wetlands large water level fluctuations are a widespread problem. Decrease of fish stocks is a threat, especially in coastal areas. Many stop-over wetlands along GWP migration routes between Southeast Europe and Africa have been seriously degraded or have disappeared, resulting in serious implications for their populations. Conservation needs are listed, but further research is recommended for both species.TUB TAK research projectTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [111T465]; ECEuropean Commission Joint Research CentreEuropean Community (EC) [LIFE05 NAT/RO/000169]; Swarovski Optik; Station Biologique de la Tour du Valat through the Foundation 'Le Balkan'; MAVA Foundation through the Society for the Protection of Prespa; Station Biologique de la Tour du Valat; Society for the Protection of Prespa; WWF GreeceTaej Mundkur, Nyambayar Batbayar, Piotr Cwiertnia, Andrej Vizi, Gennady Molodan, Simba Chan, Menxiu Tong, Zinovey Petrovych and Giannis Roussopoulos are thanked for providing unpublished information and/or for comments on an earlier draft. The Hellenic Ornithological Society provided International WaterBird Census data for both species in Greece. The work of M.S., O.O. and O.G. in Turkey was funded by a TUB TAK research project (No. 111T465). The conservation and monitoring activities in Romania between 2005 and 2009 were co-funded by the EC through the project LIFE05 NAT/RO/000169. The work in Srebarna was funded by Swarovski Optik and the Station Biologique de la Tour du Valat through the Foundation 'Le Balkan'. The work in Prespa, Am vrakikos and Kerkini in Greece was funded by the MAVA Foundation through the Society for the Protection of Prespa and the Station Biologique de la Tour du Valat, and G.C. was supported by the Society for the Protection of Prespa and WWF Greece. D. Tommy King, Dan Chamberlain, Hans Kallander and an anonymous re viewer made many useful suggestions that improved an earlier draft. Julia Henderson corrected our gross mistakes in the use of the English language
Author response image 1.
No full textBiomarkers for patient selection are essential for the successful and rapid development of emerging targeted anti-cancer therapeutics. In this study, we report the discovery of a novel patient selection strategy for the p53–HDM2 inhibitor NVP-CGM097, currently under evaluation in clinical trials. By intersecting high-throughput cell line sensitivity data with genomic data, we have identified a gene expression signature consisting of 13 up-regulated genes that predicts for sensitivity to NVP-CGM097 in both cell lines and in patientderived xenograft models. Interestingly, these 13 genes are known p53 downstream target genes, suggesting that the identified gene signature reflects the presence of at least a partially activated p53 pathway in NVP-CGM097-sensitive tumors. Together, our findings provide evidence for the use of this newly identified predictive gene signature to refine the selection of patients with wild-type p53 tumors and increase the likelihood of response to treatment with p53–HDM2 inhibitors, such as NVP-CGM097
WAVELENGTH AND TIME EVOLUTION OF MULTIPLE STIMULATED RAMAN SPECTRA IN EXCITED BY AN INTENSE PICOSECOND LASER PULSE
No full textAuthor Institution: Section Biology, Institut de Radium; Laboratoire de Photosynthese, GIF; P.N. Lebedev Physical Institute, USSRBy focussing a giant laser pulse, delivered by a mode-locked Nd-YAG laser, Into , under specified conditions, a discrete train of stimulated Raman bands was observed. On the anti-Stokes side for instance, using a multichannel spectroscopy method, over 30 bands of very high intensity were recorded, ranging from 1.06 to below 400 nm. Under the conditions of the experiments, no continuum was detected between the bands. The time evolutions of the various bands were simultaneously examined, using a high speed deflection camera. The following features were observed: 1) the durations of the stimulated Raman bands are always less than that of the excitation laser pulse (either or 532 nm), 2) the durations of the individual, stimulated Raman bands decrease steadily, as the bands are more distant from the excitation line, 3) the durations of the bands which are far away from the excitation line are below the time resolution capability of the camera used, i.e., 6 ps
Offspring microbiomes differ across breeding sites in a panmictic species.
No full text16 pagesInternational audienceHigh dispersal rates are known to homogenize host’s population genetic structure in panmictic species and to disrupt host local adaptation to the environment. Long-distance dispersal might also spread micro-organisms across large geographical areas. However, so far, to which extent selection mechanisms that shape host’s population genetics are mirrored in the population structure of the enteric microbiome remains unclear. High dispersal rates and horizontal parental transfer may homogenize bacterial communities between breeding sites (homogeneous hypothesis). Alternatively, strong selection from the local environment may differentiate bacterial communities between breeding sites (heterogeneous hypothesis). Furthermore, selection from age-specific environmental or physiological factors may differentiate the microbiome between juveniles and adults. Here, we analyzed the cloacal bacterial 16S rRNA gene of fledgling greater flamingos, Phoenicopterus roseus, across nine western Mediterranean breeding sites and four breeding seasons (n = 731) and adult birds (n = 27) from a single site. We found that fledgling cloacal microbiome, as measured by alpha diversity, beta diversity, the relative abundance of assigned sequence variants (ASVs) belonging to a phylum and genus composition within phylum, varied significantly between sampling sites and across time within site despite high adult dispersal rates. The spatio-temporal effects were stronger on individual ASV absence/presence than on ASV abundance (i.e., than on core microbiome composition). Spatial effects had a stronger effect than temporal effects, particularly on ASV abundance. Our study supports the heterogeneous hypothesis whereby local environmental conditions select and differentiate bacterial communities, thus countering the homogenizing effects of high-dispersing host species. In addition, differences in core microbiome between adult vs. fledgling samples suggests that differences in age-specific environmental and/or physiological factors result in differential selection pressure of core enteric microbiome between age classes, even within the same environment. In particular, the genus Corynebacterium, associated with both seasonal fat uptake and migration in previous studies, was much more abundant in high-dispersing fledglings than in more resident adults. To conclude, selection mechanisms that shape the host’s genetic structure cannot be extended to the genetic structure of the enteric microbiome, which has important implications regarding our understanding of both host local adaptation mechanisms and enteric microbiome population genetics
0002
No full textDAILY PM.0 ALTO TIMES. FRIDAY. APRIL 22,. 1914
PAGE THREE.
Program Announced far(tJ^;™~."- »
Bromfteld Song
Recital
Rare Taste of Artist and Runs
Gamut of Composers.
Tbe Hwdcnin.g f-xocess.
H« w«al without underwear half of
hit life.
Jut u> harden himietf
He boasted—eotnetlmee came a
boast from his wife—
How be hardeaed hlmaelf.
' (• overcoat **er was mera on his
form.
And *ret he contended be always was
warm—
He feared not the bllsxard. be feared
not .the storm.
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ilm Kahne Orel*
! Mem Uebe 1st Gssien Brabna
Mies Bromfleld.
I Tbe csll of Lo-ra A-rlw-ard
Selection of Numbers Reveals a BanJ** Son* Homer
were 1 Some Star Foeiste.-
Mr.McLoi**
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b-een glvea ont for tbe rarden re-' Uahn
cltsl which ta to Uke place oo the. Miroio, Dltes-Mol Weckerlln
premises of Mn. Tbeophllas Allen | -ttlsi, Bromfleld.
nt the comer of Melville STesae and i Erotlk - Grieg
Webster street. Sunday afternoon at! An Den Pruehltng Grieg
.1:30 o'clock. Mlrs Grace Bromfleld.' Mrs. Staber
the principal eolotst. wilt appear in'F^rom the l-*m1 or the Sky Blue
three groups of tongs and will ■inc. Water Cadman
An-Jltfe "Psrla Walts" as ihe final Morning Hymn Henacbel
number. . Irish I^ore Son;: - . ... .Lang
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low appear [be names of Cadman. Tickets for tbe recital ha**e been! E'eu when ll was twenty i>r thirty
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and other* Mr Robert McLur***. cenU. and admliston may be pro- He •-oil Id burden himself
the pia»orlaie voeallst, hu chosen cured Sunday at tbe place of thel
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Additional Sunday Car Service
to Congress Springs Commencing Sunday
April 26,1914
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Some Odd Porch Chairs
and Rockers
] to be disposed of before our new stock arrives.
Call early and make your selection
I
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(INCORPORATED)
m :*. a hi and 1 * 30 J .. .
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, the iiitimciiml chair nine times run-1 g'
222 University Ave.
f*nrm»2e**m*oi**n*2e*n*e*more*m*
NOVELTY THEATER
TONIGHT LAST CHANCE
Charles Klein author of the Third Degree presents his masterpiece
"LION'"»* MOUSE"
Magnificent Reels
The Most Talked Of Play Of The Age
George Soule Spencer, as John Ryder the money king, (The Lion), F.thel Clayton, as Shirley Rossmore
the daughter of the ruined judge, (The Mouse), and a strong cast of Nsa* York's greatest actors including
Bartley McCuIlom, Bleanor Berry, Richard Morris, Gaston Bell, Ruth Bryan and Liilie Leslie.
Adults 25c First Show 7:15 Second Show 9:00, Children 10c
This is the picture that ran for two consectutive weeks in lhe new Tivoli Theater San Francisco, to capacity busines
Search for B-c(+) decays to two charm mesons
No full textA search for decays of B-c(+) mesons to two charm mesons is performed for the first time using data corresponding to an integrated luminosity of 3.0 fb(-1), collected by the LHCb experiment in pp collisions at centre-of-mass energies of 7 and 8 TeV. The decays considered are B-c(+)-> D-(s)(()*())(+) (D) over bar (()*()0) and Bc(+)-> D-(s)(()*D-)+(()*())(0), which are normalised to high-yield B+-> D-(s)(+)(D) over bar (0)decays. No evidence for a signal is found and limits are set on twelve B-c(+) decay modes. (C) 2018 The Author(s). Published by Elsevier B.V
Measurement of the CP-violating phase phi(s) from B-s(0) -> J/psi pi(+)pi(-) decays in 13 TeV pp collisions
No full textDecays of B-s(0) and (B) over bar (0)(s) mesons into J/psi pi(+)pi(-) final states are studied in a data sample corresponding to 1.9 fb(-1) of integrated luminosity collected with the LHCb detector in 13 TeV pp collisions. A time-dependent amplitude analysis is used to determine the final-state resonance contributions, the CP-violating phase phi(s) = -0.057 +/- 0.060 +/- 0.011 rad, the decay-width difference between the heavier mass B-s(0) eigenstate and the B-0 meson of -0.050 +/- 0.004 +/- 0.004 ps(-1), and the CP-violating parameter vertical bar lambda vertical bar = 1.01(-0.06)(+0.08) +/- 0.03, where the first uncertainty is statistical and the second systematic. These results are combined with previous LHCb measurements in the same decay channel using 7 TeV and 8 TeV pp collisions obtaining phi(s) = 0.002 +/- 0.044 +/- 0.012 rad, and vertical bar lambda vertical bar = 0.949 +/- 0.036 +/- 0.019. (C) 2019 The Author. Published by Elsevier B.V
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