83,989 research outputs found
Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′
No full textFirst evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)
Quantitative comparison of cities: Distribution of street and building types based on density and centrality measures
No full textIt has been argued that different urban configurations - planned vs. organic, treelike vs. grid like - perform differently when it comes to the intensity and distribution of pedestrian flows, built density and land uses. However, definitions of urban configurations are often rather abstract, ill-defined and at worse end in fixed stereotypes hiding underlying spatial complexity. Recent publications define morphological typologies based on quantitative variables (e.g. Barthelemy, 2015; Serra, 2013a; Gil et al., 2012; Berghauser Pont and Haupt, 2010) and solve some of these shortcomings. These approaches contribute to the discussion of types in two ways: firstly, they allow for the definition of types based on multiple variables in a precise and repeattable manner, enabling the study of large samples and the comparison between both cities and regions; secondly, they frame design choices in terms of types without being fixed and so open up for design explorations where the relation between the variables can be challenged to propose new types.
This paper explores the typologies defined by Serra (2013a) and Berghauser Pont and Haupt (2010) further, as these target two of the most important morphological entities of urban form, namely the street network and the building structure. The purpose is to gain a better understanding of how types are composed and distributed within and across different cities.
The method is based on GIS and statistical modeling of four cities to allow for a comparative analysis of four cities: Amsterdam, London, Stockholm and Gothenburg. For the street network, we process the Road-Centre-line maps to obtain a clean network model, then run segment angular analysis to calculate the space syntax measures of betweenness at different metric radii, defining the “centrality palimpsest” (Serra, 2013a). For the building structure, we process elevation data to obtain building height, then run accessible density analysis for all building density metrics (FSI, GSI, OSR, L) using the Place Syntax Tool (Berghauser Pont and Marcus, 2014). The street and building types are defined using cluster analysis (unsupervised classification), following a similar approach to Serra (2013a).
The result is a typology of street (´paths´) and building types (´places´), with different profiles of centrality and density across scales. The spatial distribution and frequency of these types across the four cities gives an objective summary of their spatial structure, identifying common as well as unique traits
Letter from Carl Hayden to M. J. Riordan
No full textLetter from Carl Hayden to M. J. Riordan expressing his support for Coconino County in turning over the Bright Angel Trail to the federal government
Reply: Breast cleavage remodeling with fat grafting: A safe way to optimize symmetry and to reduce intermammary distance
No full textMotte et al. 2024MOTTE V. (dir.), AMAMI L., CORNEC T., DUCOURNAU B., LACHERT F., M., MIAILHE V., INDRAFO R., SAADI J., SERRA L., SILHOUETTE H., « 2023 : Bilan d’une année archéologique à La Réunion », Bulletin de l’Académie de l’île de La Réunion, vol. 40, 2024, pages 227 à 248
No full textLe verre dans une année d'archéologie à La RéunionMotte et al. 2024MOTTE V. (Eds.), AMAMI L., CORNEC T., DUCOURNAU B., LACHERT F., M., MIAILHE V., INDRAFO R., SAADI J., SERRA L., SILHOUETTE H., « 2023 : Report of an archaeological year in La Réunion », Bulletin of the Academy of the island of La Reunion, vol. 40, 2024, pp. 227-24
Nucleoside phosphorylases and deoxyribonucleoside kinases: the green side of nucleis acid chemistry
No full textBiocatalysis has become nowadays an important tool in synthetic organic chemistry. Biotransformations are chemo-, regio-, and stereoselective, occur under mild reaction conditions and are characterized by a reduced use of toxic reagents/solvents. One of the areas where biocatalyzed reactions have clearly shown their potential is nucleic acid chemistry. Enzymes of nucleic acid metabolism such as nucleoside phosphorylases (NPs, EC 2.4.2) and deoxyribonucleoside kinases (dNKs, EC 2.7.1) can be conveniently used as biocatalysts in the synthesis of nucleoside and nucleotide analogues.
NPs catalyze the reversible cleavage of the glycosidic bond of (deoxy)ribonucleosides in the presence of inorganic orthophosphate to generate the nucleobase and α-D-(deoxy)ribose-1-phosphate. If a second nucleobase is added to the reaction, the formation of a new nucleoside can result (transglycosylation). dNKs catalyze the regioselective transfer of a phosphate group from ATP to a nucleoside to give the corresponding nucleoside 5’-monophosphate. However, the bottleneck in the use of enzymes as biocatalysts is often their instability under experimental conditions, their cost and solubility in the reaction medium. These issues can be frequently overcome by immobilizing the enzyme on a solid support. Substrate specificity, immobilization and some synthetic applications of selected NPs1-3 and dNKs4 will be described.
References
1. Ubiali, D.; Serra, C.D.; Serra, I.; Morelli, C.F.; Terreni, M.; Albertini, A.M.; Manitto, P.; Speranza, G. Adv. Synth. Catal., 2012, 354, 96.
2. Ubiali, D.; Morelli, C.F.; Rabuffetti, M.; Cattaneo, G.; Serra, I.; Bavaro, T.; Albertini, A.M.; Speranza, G. Curr. Org. Chem., 2015, 19, 2220.
3. Calleri, E.; Cattaneo, G.; Rabuffetti, M.; Serra, I.; Bavaro, T.; Massolini, G.; Speranza, G.; Ubiali, D. Adv. Synth. Catal., 2015, 357, 2520.
4. Serra, I.; Conti, S.; Piškur, J.; Clausen, A.R.; Munch-Petersen, B.; Terreni, M.; Ubiali, D. Adv. Synth. Catal., 2014, 356, 563
Endoscopic Delayed Breast Reconstruction with Expanders and Implants via the Axillary Incision Made for Sentinel Lymph Node Biopsy or Lymphadenectomy
No full textBackground Classic techniques of delayed prosthetic breast reconstruction use the mastectomy scar as an access route. As a result, the filling of the expander must be postponed until the wounds have healed. This creates an asymmetry between the breasts with the volume changes caused by the filling of the expander, which may occur over several weeks and cause considerable discomfort. Methods Delayed breast reconstruction was performed via the axillary incision made for sentinel lymph node biopsy or lymphadenectomy with endoscopic assistance and detachment of the pectoralis major muscle. The filling of the expander and symmetrization with the contralateral breast was performed in the first stage. The expander was replaced with the definitive prosthesis 3 months later, after endoscopic capsulotomy. Fat grafting was performed to create a lipobed around the implant and to improve tissue quality. Results Sixty-two patients underwent surgery. Mean follow-up was 19 months. There were no major complications in the reconstructed breast. One case of hematoma in a contralateral breast reduction and an oil cystic mass secondary to fat grafting were recorded. In all cases, the filling of the expander with the definitive volume was possible during the first stage. Conclusions Endoscopic delayed breast reconstruction with insertion of implants through the axillary incision for sentinel node biopsy or lymphadenectomy is safe and feasible. It achieves complete intraoperative expansion, symmetry between the volumes of the breasts during the first stage, and avoids problems with the scar and the risk of extrusion, as the scar is placed remotely in the axilla
Letter from M. J. Riordan, Arizona Lumber and Timber Company, to Carl Hayden
No full textLetter from M. J. Riordan to Carl Hayden expressing his opposition to the federal government's takeover of Bright Angel Trail
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
PERFIL DA GERAÇÃO Y DOS ALUNOS DO CURSO DE ADMINISTRAÇÃO DA FACULDADE DA SERRA GAÚCHA
No full textEsta pesquisa tem como tema a Geração Y, geração que está provocando uma revolução no mercado de trabalho. O problema de pesquisa consiste em responder a pergunta: sabendo que o perfil da mesma geração pode mudar de um país para o outro e até mesmo de uma região para outra, qual é o perfil da Geração Y dos alunos da FSG? Este trabalho tem como objetivo geral analisar o perfil da geração em questão, pessoas hoje entre 18 e 29 anos, focando nos estudantes do curso de administração da Faculdade da Serra Gaúcha. Nesse sentido, a discussão teórica aborda as definições das gerações: os tradicionais, baby-boomers, Geração X e a Geração Y, sendo estes últimos também chamados de Echo Boomers, Os Conectados, Millenials ou Geração Net. Os anos de nascimentos adotados por Oliveira (2008) para esta geração são os anos entre 1978 e 1991. Quanto à metodologia, trata-se de uma pesquisa quanti-qualitativa, uma vez que se utiliza de dados estatísticos e ao mesmo tempo de opiniões. Em relação à natureza da pesquisa, caracteriza-se como exploratória, por envolver entrevistas com professores e gestores ligados a estes jovens e análise de pesquisas realizadas por instituições como o Atêlie de Pesquisa Organizacional. Também é descritiva já que visa definir o perfil dos novos profissionais. Ela também é de levantamento visto que para que essa análise seja realizada, há também a necessidade da pesquisa de levantamento, que “caracterizam-se pelo questionamento direto das pessoas, cujo objetivo é obter as informações necessárias para o desenvolvimento de novas ações.” (BERLATTO, 2011, p.15). Quanto à coleta de dados, serão utilizados instrumentos quantitativos e qualitativos. O questionário, que é o instrumento quantitativo, foi aplicado a uma amostragem de alunos da Faculdade da Serra Gaúcha, Já a entrevista foi realizada com alguns professores da área de Administração na FSG (Faculdade da Serra Gaúcha) e profissionais da área de Recursos Humanos a respeito de suas opiniões sobre o tema, e o modo como eles vêem os integrantes da Geração Y. Entre os principais resultado mostra-se a preocupação dos jovens pelo equilíbrio entre vida profissional e pessoal e pela busca constante por novas oportunidades no mercado de trabalho. Eles também buscam construir uma carreira sólida de forma gradual e o querem reconhecimento. Em relação às redes sociais, o Orkut ainda domina a maior parte dos internautas, mas o Facebook vem ganhando espaço. Em síntese é possível afirmar que a Geração Y de Caxias do Sul, alunos da Faculdade da Serra Gaúcha, têm ambições e querem condições melhores de trabalho, mas tem bases sólidas e sabem que é necessário tempo e dedicação para alcançarem os seus objetivos
- …
