260 research outputs found
Bondar Andriy Danylovych
No full textУ статті відображено життєвий і творчий шлях Андрія Даниловича Бондаря, вченого-дослідника, у полі зору якого були проблеми історії освіти та виховання, дидактики вищої школи. Представлено науковий доробок автора та його вклад у розбудову освіти в Україні за радянських часів.The article deals with the life and creative way of Andriy Danilovich Bondar, a researcher and scientist, who studied issues of the history of education, didactics of higher education. The scientific contributions of the author and his contribution to the development of education in Ukraine during the Soviet times are presented in article
Modern strategies of platinum resistance overcoming in patients with the serous ovarian cancer
No full textThe study was aimed to determine the platinum-resistance biomarkers in patients with ovarian cancer. The expression of ABCA1 is higher in platinum-resistant cases of ovarian cancer. The most pronounced relationship exists between the values of survivin expression, local activity of nitric oxide, the expression of glutathione dependent enzymes, the content of catecholamines in erythrocytes, and the expression of ABCA1 transporte
QUALITY OF LIFE OF PATIENTS WITH OVARIAN CANCER OF THE THIRD STAGE USING DIFFERENTIATED TREATMENT
No full textThe aim of this research was to assess the quality of life in patients with stage III ovarian cancer during the treatment period, depending on the applied therapeutic approaches.
A comparative analysis of the results of treatment of 350 patients with adenocarcinoma of the ovaries of III-IV stage, which have undergone suboptimal or non-optimal cytomelective surgery, was conducted. To assess the quality of life and to examine the relationship between changes in physical health and quality of life, patients in both groups were asked to complete the questionnaires EORTC QLQ-C30 and SF-36. According to the questionnaire of the EORTC QLQ-C30, the indicators of physical activity, the ability to do everyday affairs, were higher in the second group of patients who received differentiated treatment. The indicator of "social functioning" was also higher in the II group of patients. When evaluating the patients' liver on the scale of the questionnaire SF-36, it was found that the positive effect of differentiated therapy is maintained for 3 years. Life quality is an important criterion for evaluating the results of antitumor therapy, and when it is continuously monitored in patients with ovarian cancer the safety of treatment for patients could be improved, including at an advanced stage</jats:p
Graphics by Andriy Levytskyi
No full textАндрій Левицький – цікавий сучасний український графік, широко відомий як в Україні, так і за кордоном, володар низки престижних міжнародних відзнак за найкращі твори в галузі графічного мистецтва. На межі 1980–1990-х років художник виконав серію офортів, присвячених Києву, де поєднав загальновідомі архітектурні пам’ятки із символічними та алегоричними образами («Будинок Городецького», «Київська Лавра», «Андріївська церква», «Богородиця» (усі – 1987–1990 рр.)). Тему було продовжено в серіях «Мій Київ-1» та «Мій Київ-2» (об. – 1996). Найвиразнішими творами Андрія Левицького стали «панорами» – довгі горизонтальні фризи, техніку виконання яких митець визначає як інталіо («Road to Town», «Love Comes in The Town» (об. – 2002), «Talking to myself» (2004), «Pine Spirit», «Dreamscape» (2005)); різновидом «панорами» можна вважати також вертикальний «сувій» («Geografica Nova» (2007)). «Панорами» є своєрідними уявними пейзажами, в яких фентезійна архітектура гармонійно поєднується з прекрасними природними мотивами, особливе місце серед яких належить улюбленим графіком деревам. Також «панорами» містять численні музичні асоціації, натяки на особисті спогади та враження автора, що надає їм особливої відвертості та інтимності. Тематично до «панорам» примикає й робота «Мій острів» (2010). Тема техніки, яка підкорює різні стихії – землю, воду, повітря – але при тому не псує та не знищує навколишнє середовище, а радше стає його продовженням та органічною частиною, виникає в інталіо «Railroad», «АВІА», «Комети», «Польоти» (усі – 2009), «Aerostation» (2013), серіях «Вітрильники» (2017) і «Вітрильники-2» (2018). Чимало творів Андрія Левицького присвячено також деревам («Дерево» (2013), «My Trees», «My Life» (об. – 2014), «My Greece» (2018), «Дерево жука. Сад» (2019)). Своєрідний підсумок своєму розумінню гармонії художник підводить в аркушах «Гіпопотам і ромашка» (2012) і «Равлик» (2013), де всі без виключення живі мешканці землі, а також вітрильники та ретро-літаки, співіснують у щільному, але мирному та дружньому сусідстві.Andriy Levytskyi is an interesting modern Ukrainian graphic artist, widely known both in Ukraine and abroad, a winner of a number of prestigious international awards for the best works in the field of graphic art. The artist has performed a series of etchings devoted to Kyiv at the turn of the 1980s – 1990s, combining well-known architectural monuments with symbolic and allegorical images (The House of Horodetskyi, Kyiv Lavra, St. Andrew’s Church, Theotokos (all of 1987–1990)). The theme is continued in the series My Kyiv-1 and My Kyiv-2 (both in 1996). Panoramas have become the most expressive works of Andriy Levytskyi. These are long horizontal friezes, which technique is defined by the artist as intaglio (Road to Town, Love Comes in The Town (both of 2002), Talking to Myself (2004), Pine Spirit, Dreamscape (2005)); a vertical “scroll” can also be considered as a kind of “panorama” (Geografica Nova (2007)). Panoramas are considered a peculiar kind of imaginary landscape, where fantasy architecture is combined harmoniously with beautiful natural motifs. A special place among them belongs to trees beloved by the graphic artist. Panoramas also contain numerous musical associations, allusions to personal memories, and impressions of the author, that lend them a special sincerity and intimacy. The work My Island (2010) also belongs to the Panoramas thematically. The topic of technical devices, which conquer various elements – earth, water, air – but do not spoil or destroy the environment, but rather become its continuation and integral part, appears in the intaglio Railroad, AVIA, Comets, Flights (all of 2009), Aerostation (2013), in the series Sailers (2017) and Sailboats-2 (2018). Quite a few works of Andriy Levytskyi are also dedicated to trees (Tree (2013), My Trees, My Life (both of 2014), My Greece (2018), Beetle’s Tree. Garden (2019)). The artist sums up his understanding of harmony in the sheets Hippo and Chamomile (2012) and Snail (2013), where all living inhabitants of the earth without exception, as well as sailors and retro planes, coexist in a close but peaceful and friendly neighborhood
Understanding and self-understanding in the novel “Andriy Lahovskyi” by Ahatanhel Krymskyi
No full textУ статті зосереджено увагу на різних аспектах філософської проблеми розуміння і саморозуміння,
порушеної в романі Агатангела Кримського "Андрій Лаговський". Автор статті простежує,
як комунікативні непорозуміння між персонажами, зрештою, приводять їх до усвідомлення ролі
Іншого в процесі розуміння світу і самих себе, а також намагається довести, що діалог з Іншим і
собою стає центральною проблемою не лише для персонажів роману, а й для його автора.The article deals with various aspects of the philosophical problem of understanding and selfunderstanding,
raised in the novel Andriy Lahovskyi, by Ahatanhel Krymskyi. The author of the article
traces how communicative misunderstandings between characters lead them, in the end, to a comprehension
of the role of the Other in the process of understanding the world and one-self, as well as tries to prove that
dialogue with the Other and the Self presents the central problem not only for characters in the novel, but
also for its author
Documents from Andriy Zhuk's personal fund from the period of First World War (Part 1)
No full textThe purpose of the study is to introduce into scientific circulation new, previously unpublished archival materials of the early twentieth century. and the period of national liberation struggles in Ukraine. Documents from the personal fund of Andriy Zhuk – a prominent Ukrainian revolutionary of the UPR, public and political figure, one of the first founders of cooperative organizations in the Ukrainian lands, which are stored in the Central State Archive of Supreme Authorities and Administration of Ukraine in Kyiv (TsDAVO of Ukraine) and cover the activities of members of the Union for the Liberation of Ukraine. These documents outline the active socio-political activities of Andriy Zhuk during the First World War, allow to get acquainted with the political views, beliefs, life position of this prominent revolutionary and statesman of the Ukrainian People’s Republic 1917–1921. We hope that these documents will be useful to historians, who study the history of Ukraine in the first half of the twentieth century, sources, local historians, as they shed light on some pages of our glorious history. Documents are submitted with preservation of language, spelling, punctuation of originals. The scientific novelty of the work is due to the preparation of the publication and the introduction into scientific circulation of previously unknown sources from the personal fund of Andriy Zhuk. Introduction to the scientific circulation of documents of the archival fund № 3807, in particular, unpublished epistolary, manuscripts of A. Zhuk and program documents of parties, societies, the author of which he was, allows scientists to study the features of the Ukrainian socio-political movement of the early XX century
THE EXPERIENCE AND RESULTS OF CYTOREDUCTIVE SURGERY AND HIPEC USED IN ADVANCED OVARIAN CANCER
No full textThe research object was life quality of patients with ovarian cancer after complex treatment. Nowadays cytoreductive surgery and HIPEC is the mainstay of management of advanced stages ovarian cancer.
Description of the problem: study was conducted to assess the effectiveness of combined treatment in IIIA-IIIC ovarian cancer, its impact on quality of life.
Main scientific results: 37 patients of main group (CRS + HIPEC) were compared with 25 patients of control group (surgery + systemic chemotherapy). The quality of life was assessed with Medical Outcomes Study 36-Item Short Form Health Survey (SF-36). Comparative analysis of quality of life 6 months after treatment completion did not show significant statistical difference. Combination of cytoreduction with HIPEC improves quality of life in patients with ovarian cancer, is tolerated better and has less systemic toxicities than systemic chemotherapy.
The area of practical use of research results: hyperthermic intraperitoneal chemotherapy is performed for patients suffering from malignant tumors of the abdominal cavity, including metastatic colon cancer, ovarian cancer, stomach cancer, pseudomyxoma, mesothelioma, rhabdomyosarcoma, and some other types of oncology.
Innovative technological product: combination of cytoreduction with HIPEC improves quality of life in patients with ovarian cancer.
Scope of application of an innovative technological product: HIPEC is an innovative treatment option for advanced cancer that has spread to the abdominal cavity (carcinomatosis) and has not gone beyond it
Epidemiology of papillomavirus infection in Ukraine
No full textThe aim of this study was to assess the prevalence of HPV infection among women in different regions of Ukraine.
Materials and methods. An analysis of data from the Quintip Recordati database, containing 195 records, was performed using frequency analysis methods. The distribution of different HPV strains among the women surveyed, who live in different regions, was determined. An analysis of the frequency of seropositive results depending on the degree of urbanisation was performed. The main ways of preventing HPV infection were identified.
Results. It was found that the number of positive tests accounted for 38.5% of the total sample. When comparing the frequency of detection of high-oncogenic strains, it was found that they are more often registered in cities with larger populations.
Conclusions: 1. The prevalence of HPV in the women examined is twice the European average. 2. The frequency of detection of highly oncogenic HPV strains is higher in urbanised regions. 3. Widespread implementation of HPV screening methods in Ukraine could significantly reduce the incidence of cervical cance
When endometrioma becomes malignant: a clinical case and conclusions for oncogynecological practice
No full textObjective. To evaluate the clinical and morphological features of malignant transformation of ovarian endometrioma and to emphasise the importance of oncological vigilance in the management of patients with endometriosis.
Materials and methods. A clinical case of early endometrioid carcinoma of the ovary against the background of endometrioma in a woman of reproductive age is presented. An analysis of current literature data and ESGO, ESHRE, and JSGO recommendations for the diagnosis and treatment of such patients was performed.
Results. Morphological and radiological signs of increased oncological risk were identified, which became the basis for timely surgical intervention. Endometrioid carcinoma G1, FIGO IA was histologically verified. Fertility-preserving staging surgery was performed. No recurrence was detected during 24 months of follow-up.
Conclusions. Ovarian endometrioma can be a source of early gynaecological cancer processes even in young patients. Vigilance, high-quality imaging and adequate surgical tactics are key factors for successful treatment
Documents from Andriy Zhuk’s personal fund from the period of First world war (part 1)
No full textМетою дослідження є запровадження до наукового обігу нових, раніше не
опублікованих архівних матеріалів початку ХХ ст. та періоду національно-визвольних змагань в Україні. Представлені документи з особистого фонду Андрія
Жука – видатного українського революціонера часів УНР, громадсько-політичного діяча, одного з перших фундаторів кооперативних організацій на українських
землях, які зберігаються в Центральному державному архіві вищих органів влади
та управління України у м. Києві (ЦДАВО України) та висвітлюють діяльність
членів Союзу Визволення України. Наведені документи окреслюють активну суспільно-політичну діяльність Андрія Ілліча Жука у роки Першої світової війни, дозволяють детальніше познайомитися з політичними поглядами, переконаннями,
життєвою позицією цього видатного революціонера і державного діяча Української Народної Республіки 1917–1921 рр. Сподіваємося, що ці документи будуть корисні історикам, які досліджують історію України першої половини ХХ ст.,
джерелознавцям, краєзнавцям, оскільки вони проливають світло на окремі сторінки нашої славетної історії. Документи подано із збереженням мови, орфографії, пунктуації оригіналів. Наукова новизна роботи зумовлена підготовкою
публікації та введенням до наукового обігу раніше невідомих джерел з особового
фонду Андрія Ілліча Жука. Запровадження до наукового обігу документів архівного фонду № 3807, зокрема, неопублікованого епістолярію, рукописів А. Жука і програмних документів партій, товариств, автором яких він був, дозволяє науковцям вивчити особливості українського суспільно-політичного руху початку XX ст.The purpose of the study is to introduce into scientific circulation new, previously
unpublished archival materials of the early twentieth century. and the period of national
liberation struggles in Ukraine. Documents from the personal fund of Andriy
Zhuk – a prominent Ukrainian revolutionary of the UPR, public and political figure,
one of the first founders of cooperative organizations in the Ukrainian lands, which
are stored in the Central State Archive of Supreme Authorities and Administration of
Ukraine in Kyiv (TsDAVO of Ukraine) and cover the activities of members of the Union
for the Liberation of Ukraine. These documents outline the active socio-political activities
of Andriy Zhuk during the First World War, allow to get acquainted with the
political views, beliefs, life position of this prominent revolutionary and statesman of
the Ukrainian People’s Republic 1917–1921. We hope that these documents will be
useful to historians, who study the history of Ukraine in the first half of the twentieth
century, sources, local historians, as they shed light on some pages of our glorious history.
Documents are submitted with preservation of language, spelling, punctuation of
originals. The scientific novelty of the work is due to the preparation of the publication
and the introduction into scientific circulation of previously unknown sources from the
personal fund of Andriy Zhuk. Introduction to the scientific circulation of documents
of the archival fund № 3807, in particular, unpublished epistolary, manuscripts of A.
Zhuk and program documents of parties, societies, the author of which he was, allows
scientists to study the features of the Ukrainian socio-political movement of the early XX century
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