680 research outputs found

    Post cards (6) 1895-1896

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    (1) Post card to P.H.L. Bradt, Pelham Union, stamped Canadian Pacific Railway, 30 April 1895, Woodstock, Ont. The signature is unclear. The note states “…you don’t oftener think of me than I do of you & I’m bound to come & see you soon as I can—I expect to leave here 5:18 p.m. May 6 by G.T.R., have written James…” (2) Post card to James J. Bradt, Beamsville, Ont., from T. Balis, dated at Smithville, 4 July 1895. The note states “…Father died today. Funeral Saturday at 2 p.m. Please send word to Peter.” (3) Post card to Peter Bradt, Pelham Union, dated at Beamsville, 6 November 1895. The signature on the card is not clear. The note comments on the cost of hay. (4) Post card to Peter H.L. Bradt, Pelham Union from P.H. Cline (Clive?), dated at Jordan Station, 3 February 1896. The note states “…Everything is all right down here. The hay is all sold…” (5) Post card to P.H.L. Bradt, Pelham Union, from P.H. Cline (Clive?), dated 19 August 1896. The note states “…the thrashers will be here the 21…if you came they will be here in the morning…” (6) Post card to P.H.L. Bradt, Pelham Union, from P.H. Cline (Clive?), dated at Jordan Station, 9 September 1896. The note states “…will you kindly come down on Friday the 11 and see about cleaning seed wheat if you have time…

    Peter van Lint, a troubled case in the 17th. century Flemish painting

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    Tesis de la Universidad Complutense de Madrid, Facultad de Geografía e Historia, leída el 05-09-2018El objetivo del presente trabajo es la elaboración de una monografía sobre la figura del pintor de Amberes Peter van Lint 1609-1690 y su obra, conocido hasta ahora de forma parcial y fragmentaria. Sin embargo, uno de los aspectos más destacados y estudiados es la abundante presencia de su obra en España actualmente.La metodología seguida se basa en la realización de un catálogo razonado que reúna toda la obra (pintura, dibujo, grabado y composiciones para tapices) conocida y publicada, a la cual incorporamos aquí algunas nuevas atribuciones a la mano de van Lint. En primer lugar, hemos reunido 57 obras firmadas y fechadas con el propósito de reflexionar sobre la evolución de su estilo; 155 pinturas atribuidas y firmadas catalogadas según el asunto; 30 dibujos; 13 grabados y 5 composiciones para tapices. Además, se añaden 25 pinturas atribuidas a su taller, 4 clasificadas como copias de obras de van Lint, y 22 piezas rechazadas, que nos ayudan a completar el panorama de la obra de este maestro.En segundo lugar, todos los asuntos recogidos en este catálogo se estudian en relación con aquellos recogidos en los dos protocolos testamentarios de 1680 y 1690. Se dedica especial atención al primero, un inventario de los bienes de la propia casa de van Lint, que distingue diversas categorías de pinturas como principael o copije así como otras especificaciones técnicas importantes. El segundo protocolo, un libro de venta, recoge el precio y el nombre de los herederos y compradores, además del asunto...The objective of this present work is to produce a monograph on the painter from Antwerp Peter van Lint (1609-1690) and his oeuvre, known up to now only partially and fragmentarily. Nevertheless, one of the most remarkable and studied aspects is the abundant presence of his work in Spain nowadays.The methodology of this thesis is based on the making of a catalogue raisoneé, which has brought together all the known and published paintings, drawings, engravings and compositions for tapestries, to which we have added here some newly attributed pieces to van Lint’s hand. First of all, we have gathered 57 signed and dated pieces for the purpose of analyzing his style evolution; 155 attributed and signed paintings organized by subjects; 30 drawings; 13 engravings, and 5 compositions for tapestries. Moreover, the addition of 25 paintings ascribed to the workshop, 4 labeled as copies from van Lint’s, and 22 rejected pieces, help complete a comprehensive panoramic view of the master’s oeuvre. Secondly, all the subjects collected in the whole catalogue are thoroughly studied in relation with those registered in two testamentary protocols from 1680 and 1690. Special attention is dedicated to the first protocol, an inventory of the assets kept in van Lint’s own house, and which differentiates painting categories such as principael or copije as well as other important technical specifications. The second one, a sales book, in addition to the subject compiles the price and buyers and heirs’ names...Fac. de Geografía e HistoriaTRUEpu

    (–)-Epicatechin reduces blood pressure and improves vasorelaxation in spontaneously hypertensive rats by NO-mediated mechanism

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    Studies in humans have found consumption of certain flavanoid-containing foods to be associated with improvement in endothelial function and with reduction of blood pressure (BP). (-)-Epicatechin is a compound representative of the flavanols (a subfamily of flavonoids), abundant in cocoa seeds, which is preserved during the industrialization process to chocolate. The antihypertensive effect of dietary (-)-epicatechin was investigated on spontaneously hypertensive rats (SHR). Consumption of (-)-epicatechin-supplemented diet (3 g (-)-epicatechin/kg diet) decreased blood pressu re (BP) in SHR by 27 and 23 mm of Hg on days 2 and 6, respectively. On day 6,a 173% increase of nitric oxide (NO) synthase activity was observed in the aorta of EPI-SHR as compared to non-supplemented SHR (p<0.05). Responses to acetylcholine (ACh) were then examined in femoral arteries in the absence and the presence of with L-NAME, a non-selective NOS inhibitor, to assess the Ach-mediated relaxation ascribed to NO-dependent and independent mechanisms Acetylcholine-induced endothelium-dependent relaxation in the femoral artery was significantly higher in EPI-SHR than in SHR, with a predominance of the NO-dependent component of this relaxation. The endothelium-independent relaxation, assayed by using the NO donor sodium nitroprusside (SNP), resulted non significant different in the three experimental groups, demonstrating an unaffected function of vascular smooth muscle cells. These results give further support to the concept that (-)-epicatechin can modulate BP in hypertension by increasing NO levels in the vasculature.Fil: Galleano, Mónica Liliana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Analítica y Fisicoquímica. Cátedra de Fisicoquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Bioquímica y Medicina Molecular; ArgentinaFil: Bernatova, Iveta. Slovak Academy of Sciences; EslovaquiaFil: Puzserova, Angelika. Slovak Academy of Sciences; EslovaquiaFil: Balis, Peter. Slovak Academy of Sciences; EslovaquiaFil: Sestakova, Natalia. Slovak Academy of Sciences; EslovaquiaFil: Pechanova, Olga. Slovak Academy of Sciences; EslovaquiaFil: Fraga, César Guillermo. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Analítica y Fisicoquímica. Cátedra de Fisicoquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Bioquímica y Medicina Molecular; Argentin

    Four-dimensional distribution of the 2010 Eyjafjallajökull volcanic cloud over Europe observed by EARLINET

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    The eruption of the Icelandic volcano Eyjafjallajökull in April–May 2010 represents a "natural experiment" to study the impact of volcanic emissions on a continental scale. For the first time, quantitative data about the presence, altitude, and layering of the volcanic cloud, in conjunction with optical information, are available for most parts of Europe derived from the observations by the European Aerosol Research Lidar NETwork (EARLINET). Based on multi-wavelength Raman lidar systems, EARLINET is the only instrument worldwide that is able to provide dense time series of high-quality optical data to be used for aerosol typing and for the retrieval of particle microphysical properties as a function of altitude. In this work we show the four-dimensional (4-D) distribution of the Eyjafjallajökull volcanic cloud in the troposphere over Europe as observed by EARLINET during the entire volcanic event (15 April–26 May 2010). All optical properties directly measured (backscatter, extinction, and particle linear depolarization ratio) are stored in the EARLINET database available at http://www.earlinet.org. A specific relational database providing the volcanic mask over Europe, realized ad hoc for this specific event, has been developed and is available on request at http://www.earlinet.org. During the first days after the eruption, volcanic particles were detected over Central Europe within a wide range of altitudes, from the upper troposphere down to the local planetary boundary layer (PBL). After 19 April 2010, volcanic particles were detected over southern and south-eastern Europe. During the first half of May (5–15 May), material emitted by the Eyjafjallajökull volcano was detected over Spain and Portugal and then over the Mediterranean and the Balkans. The last observations of the event were recorded until 25 May in Central Europe and in the Eastern Mediterranean area. The 4-D distribution of volcanic aerosol layering and optical properties on European scale reported here provides an unprecedented data set for evaluating satellite data and aerosol dispersion models for this kind of volcanic events

    EU MarcoPolo project | SO2 emission inventory over China

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    The aposteriori SO2 emissions for year 2014, in the domain from 102°E to 132°E and from 15°N to 55°N, in a 0.25°x0.25° spatial resolution and monthly temporal resolution, have been provided to the MarcoPolo project and can be found at http://users.auth.gr/mariliza/MarcoPolo/SO2_EmissionInventory/. For details on the creation of the inventory refer to http://users.auth.gr/mariliza/MarcoPolo/D3.4_SO2_emission_estimates.pdf and for the inclusion of the SO2 emission inventory to the MarcoPolo Emission Database refer to: http://users.auth.gr/mariliza/MarcoPolo/D4.2_DescriptionMarcoPoloInventory.pdf as well as http://users.auth.gr/mariliza/MarcoPolo/D4.3_assessment_impact_updated_emission_inventories_v2.0.pdf . The main reference to this dataset is found here: Koukouli, M.-E., Theys, N., Ding, J., Zyrichidou, I., Mijling, B., Balis, D., and van der A, R. J.: Updated SO2 emission estimates over China using OMI/Aura observations, Atmos. Meas. Tech. Discuss., https://doi.org/10.5194/amt-2017-256, in review, 2017. The netcdf data files contain the following structure: Dimensions lat = 129 lon = 121 Attributes author = "MariLiza Koukouli" contact information = "[email protected]" institution = "Laboratory of Atmospheric Physics, Aristotle University of Thessaloniki" time frame = "2014" sector classification = "total emissions" emis_cat_name = "sulphur dioxide emissions" source_type_name = "sulphur dioxide emissions" pollutant_description = "updated sulphur dioxide emissions based on the CHIMERE model running the MEIC emissions and the OMI/Aura observations" unit_emissions = "Mg/month" nodata_value = "-9999.0" Variables float emissions(lon, lat) </ul

    Earlinet validation of CATS L2 product

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    The Cloud-Aerosol Transport System (CATS) onboard the International Space Station (ISS), is a lidar system providing vertically resolved aerosol and cloud profiles since February 2015. In this study, the CATS aerosol product is validated against the aerosol profiles provided by the European Aerosol Research Lidar Network (EARLINET). This validation activity is based on collocated CATS-EARLINET measurements and the comparison of the particle backscatter coefficient at 1064nm.Atmospheric Remote Sensin

    The uses of madness in nineteenth- and twentieth-century fiction : the relation between narrative strategy and disturbed states of consciousness

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    The thesis operates upon the premise that there has been, in the course of the last two centuries, a radical transformation in narrative presentations of exceptional states of consciousness. It sets out to identify the main characteristics of the fictional transformation, and to situate them in the context of wider cultural shifts. I decided to rest my approach upon the relatively conservative sense that, roughly speaking, the structural and linguistic analysis of a narrative topos - that is to say the protagonist's madness - can elicit a clearer understanding of the changing, underlying dynamics and thematics of fictional works as they emerge over a given historical period. The thesis is set out in two parts; Part I explores nineteenth century uses of madness, and Part II compares and contrasts more recent treatments. The study of the different presentations of madness in fiction is organized diachronically for heuristic purposes, although the typological emphasis of the thesis must eventually take precedence over the imposition of a rigid historical framework. In the nineteenth century it is predominantly an intellectually marginalized kind of fiction (often termed 'gothic') which deals with exceptional psychic experience. It does so in a way which engages with the treacherous 'otherness' of mad experience, which is often aligned with the supernatural. In these texts the position of the narrator in relation to such phenomenon is of paramount importance. More recent treatments of 'madness' display a tendency to undermine its 'otherness' and to move towards narrative identification with such states. The method of investigation functions upon several levels. In order to provide a constructive counter-perspective upon fictional treatments of madness and to forge the link with contemporary methodologies, the study commences with the narratological analysis of a work written by a (clinically diagnosed) psychotic author which has achieved the status of a classic within psychiatric, psychoanalytical and even recent cultural theory. The narrative structure of D. P. Schreber's Memoirs finds its equivalent in a kind of fiction identified in this thesis as 'paranoid'. Twentieth century clinical discourse increasingly has recourse to the very broad term 'schizophrenia' as a synonym for the outmoded term 'madness'. The current emphasis upon linguistic concerns in the definition and location of psychosis allows the critical grouping of certain kinds of texts under the heading of 'schizoid', due to the discovery of analogous characteristics at work within their (anti)narrative strategy. Again, these terms are heuristically intended and cannot be scientifically precise. The thesis concludes with a discussion of the current centrality of a terminology of psychopathology to the ways in which fictionists, critics and theorists describe, prescribe and understand the 'postmodern' self and world. This project offers an overview of attitudes to madness as they are transformed in fiction in the course of a historical period. The way in which madness functions in these texts is, first of all, not only as the instrument of literary exploration but also as a means of transgressing boundaries between sanity and insanity. The period is crucial, further, in its radical transitional nature with regard to concepts of fundamental import for the novel form: most particularly, ideas of the 'self' and ideas of 'reality', as objectively stable or as sub. iective and illusory. For the fictional articulation of these, the topos of 'madness' serves as the ultimate measure

    Sexual Dimorphism in Cardiometabolic Diseases: The Role of AMPK

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    Cardiovascular diseases (CVDs) are the leading cause of mortality and disability among both males and females. The risk of cardiovascular diseases is heightened by the presence of a risk factor cluster of metabolic syndrome, covering obesity and obesity-related cardiometabolic risk factors such as hypertension, glucose, and lipid metabolism dysregulation primarily. Sex hormones contribute to metabolic regulation and make women and men susceptible to obesity development in a different manner, which necessitates sex-specific management. Identifying crucial factors that protect the cardiovascular system is essential to enhance primary and secondary prevention of cardiovascular diseases and should be explicitly studied from the perspective of sex differences. It seems that AMP-dependent protein kinase (AMPK) may be such a factor since it has the protective role of AMPK in the cardiovascular system, has anti-diabetic properties, and is regulated by sex hormones. Those findings highlight the potential cardiometabolic benefits of AMPK, making it an essential factor to consider. Here, we review information about the cross-talk between AMPK and sex hormones as a critical point in cardiometabolic disease development and progression and a target for therapeutic intervention in human disease
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