60,717 research outputs found
The Levi Perryman Collection, 1873-1921
No full textRecord of Levi Perryman Sheriff costs for M. W. Costers vs F. C. Taylor 4.25, A. Perryman vs R. P. Hunter 3.25. signed by F. B White
Erratum to: Effects of nutraceuticals on quality of life and sexual function of perimenopausal women (Journal of Endocrinological Investigation, (2017), 40, 1, (27-32), 10.1007/s40618-016-0500-2)
No full textUnfortunately, one of the co-author first name was wrongly published in the original version. The complete correct name of the co-author is given below. A. M. C. Rapisarda. The original version of this article is also updated
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)
No full textIn an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola
A bibliographic study of the Herbert J. Frost/W. Somerset Maugham collection in the Sterling C. Evans Library
No full textTypescript (photocopy).This dissertation is an annotated, descriptive bibliography of the 947 items in the Herbert J. Frost/W. Somerset Maugham Collection housed in Sterling C. Evans Library at Texas A&M University. Of these, the 464 primary works are separated into five categories: manuscripts, published materials, correspondence, edited materials, and introductory materials. Items are arranged alphabetically by title. The 483 secondary materials are likewise separated into five categories: books and entire periodicals, clippings, adaptations, photographs, and programs. These items are arranged alphabetically by author or title. Notes regarding inscriptions, bibliographic rarities, content, or other information are provided as needed. Entries include references to the definitive bibliography of the primary works, Raymond Toole Stott's A Bibliography of the Works of W. Somerset Maugham and/or of the secondary, Charles Sanders' W. Somerset Maugham: An Annotated Bibliography of Writings About Him. Every effort has been made to provide clear, concise information suitable to the peculiarities of the items and the needs of researchers
Hundreds of variants clustered in genomic loci and biological pathways affect human height
No full textMost common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human traits(1), but these typically explain small fractions of phenotypic variation, raising questions about the use of further studies. Here, using 183,727 individuals, we show that hundreds of genetic variants, in at least 180 loci, influence adult height, a highly heritable and classic polygenic trait(2,3). The large number of loci reveals patterns with important implications for genetic studies of common human diseases and traits. First, the 180 loci are not random, but instead are enriched for genes that are connected in biological pathways (P = 0.016) and that underlie skeletal growth defects (P<0.001). Second, the likely causal gene is often located near the most strongly associated variant: in 13 of 21 loci containing a known skeletal growth gene, that gene was closest to the associated variant. Third, at least 19 loci have multiple independently associated variants, suggesting that allelic heterogeneity is a frequent feature of polygenic traits, that comprehensive explorations of already-discovered loci should discover additional variants and that an appreciable fraction of associated loci may have been identified. Fourth, associated variants are enriched for likely functional effects on genes, being over-represented among variants that alter amino-acid structure of proteins and expression levels of nearby genes. Our data explain approximately 10% of the phenotypic variation in height, and we estimate that unidentified common variants of similar effect sizes would increase this figure to approximately 16% of phenotypic variation (approximately 20% of heritable variation). Although additional approaches are needed to dissect the genetic architecture of polygenic human traits fully, our findings indicate that GWA studies can identify large numbers of loci that implicate biologically relevant genes and pathways
Industrial Energy Efficiency as a Risk Management Strategy
No full textIndustry utilizes risk management as a tool in efforts to maximize the bottom line. Industry embraced risk management strategies in the 1960s and since then it has become a key component of a comprehensive business strategy. Peter Fusaro, author of Energy Risk Management explains, ���The risk management process reduces financial exposure associated with price volatility by substituting a transaction made now for one that would be made at a later date.��� Risk management aids companies in minimizing operational surprises or losses. In recent decades, energy has become a greater risk to profitability due to the volatility that exists in the oil and natural gas markets. Therefore, companies now consider energy as an element of their risk management portfolio. Traditional strategies to combat against unwanted exposure in this market include hedging and long term and futures contracts. However, the following explores the topic of considering energy efficiency as a risk management tool in reducing exposure to the volatility of the energy market
The long-wavelength view of GG Tau A: rocks in the ring world
No full textWe present the first detection of GG Tau A at centimetre wavelengths, made with the Arcminute Microkelvin Imager Large Array at a frequency of 16 GHz (λ = 1.8 cm). The source is detected at >6 σrms with an integrated flux density of S16GHz = 249 ± 45 µJy. We use these new centimetre-wave data, in conjunction with additional measurements compiled from the literature, to investigate the long-wavelength tail of the dust emission from this unusual protoplanetary system. We use an MCMC-based method to determine maximum likelihood parameters for a simple parametric spectral model and consider the opacity and mass of the dust contributing to the microwave emission. We derive a dust mass of Md ~ 0.1 Msun, constrain the dimensions of the emitting region and find that the opacity index at λ > 7 mm is less than unity, implying a contribution to the dust population from grains exceeding ~4 cm in size. We suggest that this indicates coagulation within the GG Tau A system has proceeded to the point where dust grains have grown to the size of small rocks with dimensions of a few centimetres. Considering the relatively young age of the GG Tau association in combination with the low derived disc mass, we suggest that this system may provide a useful test case for rapid core accretion planet formation models
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
No full textMultiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation of disability. Epidemiological studies have shown that genetic factors are primarily responsible for the substantially increased frequency of the disease seen in the relatives of affected individuals, and systematic attempts to identify linkage in multiplex families have confirmed that variation within the major histocompatibility complex (MHC) exerts the greatest individual effect on risk. Modestly powered genome-wide association studies (GWAS) have enabled more than 20 additional risk loci to be identified and have shown that multiple variants exerting modest individual effects have a key role in disease susceptibility. Most of the genetic architecture underlying susceptibility to the disease remains to be defined and is anticipated to require the analysis of sample sizes that are beyond the numbers currently available to individual research groups. In a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, we have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci. Within the MHC we have refined the identity of the HLA-DRB1 risk alleles and confirmed that variation in the HLA-A gene underlies the independent protective effect attributable to the class I region. Immunologically relevant genes are significantly overrepresented among those mapping close to the identified loci and particularly implicate T-helper-cell differentiation in the pathogenesis of multiple sclerosis
O. A. C. Review Volume XLVI Issue 5, February 1934
No full textThe focus of this issue is the preparation for College Royal and recognizing its tenth anniversary. This month's agricultural article is a report from the Dominion Parasite Laboratory on the biological control of pests. Other articles provide an account of the activities of a stage manager and the development of the field of home economics at Macdonald College in Quebec. Campus news addresses the success of the 1934 Conversazione, the commemorating of the sixtieth anniversary of the founding of O. A. C., the attendance at the Canadian Author Lecture, and the successful productions of "The Apple Cart" and "Iolanthe". The Macdonald Institute column comments on the Conversat and women's athletics activities in basketball and the rifle club. The Alumni Record supplies alumni updates.EditorialTen Years of the RoyalRamblings on the RoyalBlame it on the stage managerBiological control of insect pests in CanadaNot for girls onlyCollege lifeLiterary sectionO. A. C. sportsfolioAlumni recordMacdonald newsLetters to the editoradvertisin
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