134,353 research outputs found

    Bio-vison 2016: The second national framework plan for biotechnology promotion in Korea

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    This research was funded by the Specific Research and Development Project of the Ministry of Science and Technology.This material is based on Bio-Vision 2016 and its Report [5, 6].We are very grateful to the following members of the Biotechnology Policy Research Center: Young-Cheol Kim, Dong-Sub Yoon, Moo Woong Kim, Eun Jung Kim, Su Gil Kim, Mi jeong Park, Seong-Hoon Park, Oh-Min Joung, and Seung- Hoo Shin

    Illustration of the predictive distributions for two different players (Left: J. C. Kim; Right: B. H. Lee).

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    Illustration of the predictive distributions for two different players (Left: J. C. Kim; Right: B. H. Lee).</p

    Effect of annealing temperature on the electrical transport properties of CaRuO3-delta thin films directly deposited on the Si substrate

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    We investigate the effect of annealing temperature on the preferentially (110)-oriented CaRuO3-delta, (CRO) thin films directly prepared on Si(100) substrate by rf magnetron sputtering. Crystalline quality and electrical transport properties of the CRO thin films were modified by post-annealing treatment. It was obvious that 700 degrees C post-annealing brought about excellent metallic characteristics with the elevation of carrier concentration and mobility. From this result, we suggested that enhanced (110) orientation, and the ratio of chemical composition Ru4+/Ca2+ ion were responsible for the transport properties of CRO thin film. (C) 2007 WILEY-VCH Verlag GmbH &amp; Co. KGaA, Weinheim.‘Brain Korea 21’ project. We appreciate the measurement of transport property using a He cryostat (Korea Basic Science Institute), and also thanks to Mr. Yunseok Kim for measuring of atomic force microscopy (KAIST)

    Symplocarpus koreanus J. S. Lee, S. H. Kim & S. C. Kim 2021

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    Symplocarpus koreanus J.S. Lee, S.H. Kim & S.C. Kim (2021: 2) Isotype: KOREA, Gangwon-do: Chuncheon-si, Sabuk-myeon, Goseong-ri, Mt. Yonghwasan, 21 March 2020, S. C. Kim 200321500 (NIBRVP815477; Fig. 1 -23). Paratypes: KOREA, Gyeonggi-do: Gapyeong-gun, Buk-myeon, Baekdun-ri, Mt. Yeoninsan, 3 May 2013, W. B . Lee s.n. (NIBRVP517078); Gapyeong-gun, Oeseo-myeon, Mt. Hwayasan, 26 June 2007, W. K. Paik VP-KB-377062-0173 (NIBRVP815507); Gapyeonggun, Sang-myeon, Haenghyeon-ri, Mt. Chungnyeongsan, 31 March 2012, J. H . Kim, Y. J. Kim & I. S. Yoon KIMJH12006 (3 sheets, NIBRVP355001); Gapyeong-gun, Sang-myeon, Haenghyeon-ri, Mt. Chungnyeongsan, 29 March 2016, G. H . Nam, J. H. Kim & J. K. Hong L 16001 (NIBRVP550794); Gapyeong-gun, Seorak-myeon, Mt. Yumyeongsan, 4 April 2008, B. K . Kwon 080404-375 (NIBRVP532404); Gapyeong-gun, Seorak-myeon, Mt. Yumyeongsan, 4 April 2008, G. Y . Chung ANH-en-080404- 001 (NIBRVP197125); Hanam-si, Baealmi-dong, Mt. Geomdansan, 3 April 2007, J. O . Hyun, H. K. Park & J. A. Eom VP-NAPI-377054-092 (NIBRVP111433); Namyangju-si, Hwado-eup, Mt. Cheonmasan, 15 April 2007, W. K . Paik VP-KB-377061-0133 (NIBRVP815506); Namyangju-si, Hwado-eup, Mt. Cheonmasan, 22 March 2013, Song et al. s.n. (NIBRVP464822); Namyangjusi, Onam-eup, Onam-ri, Mt. Cheonmasan, 6 April 2009, G. H . Nam, M. H. Kim & J. H. Lee VS 15 (NIBRVP206699); Namyangjusi, Onam-eup, Onam-ri, Mt. Cheonmasan, 6 April 2009, G. H . Nam, M. H. Kim & J. H. Lee VS16 (2 sheets, NIBRVP206700); Namyangju-si, Mt. Chungnyeongsan, 28 March 1999, S. P . Hong & K. W. Park 411 (NIBRVP102296). Gangwon-do: Cheorwon-gun, Geunnam-myeon, Mt. Gwangdeoksan, 12 May 1997, S. P . Hong & H. S. Choi 99 (NIBRVP102297); Donghae-si, Bugok-dong, Mita Temple, 26 April 2011, G. H . Nam & W. J. Jeong SHY2-34 (NIBRVP284290); Gangneung-si, Wangsan-myeon, Mt. Hwaranbong, 30 April 2009, J. H . Kim & H. J. Kim VP-KB-0904-0071 (NIBRVP318582); Hwacheon-gun, Mt. Baekjeoksan, 24 May 2000, K . Ch. Yang & J. D. Jung s.n. (NIBRVP102304, NIBRVP102305); Hwacheon-gun, Mt. Baekjeoksan, 3 August 2000, J. H . Kim & D. K. Kim 49 (NIBRVP102307); Hwacheon-gun, Sanae-myeon, Mt. Gwangdoeksan, 7 April 2009, G. H . Nam, M. H. Kim & J. H. Lee VS24 (2 sheets, NIBRVP206708); Hwacheon-gun, Sanae-myeon, Mt. Gwangdoeksan, 7 April 2009, G. H . Nam, M. H. Kim & J. H. Lee VS25 (2 sheets; NIBRVP206709). Chungcheongbuk-do: Danyang-gun, Gagok-myeon, Mt. Sobaecksan, 17 May 1999, C. W . Park, H. W. Lee & J. Koh 10315 (NIBRVP815505); Danyang-gun, Gagok-myeon, Mt. Sobaeksan, 20 April 2007, G. Y . Chung ANH-en-070420-013 (NIBRVP121631). Jeollabuk-do: Jangsu-gun, Gyenam-myeon, Jangan-ri, 21 September 1997, B. Y . Sun & C. H. Kim 10361 (NIBRVP815504); Jangsu-gun, Gyenam-myeon, Mt. Jangansan, 19 May 2007, B. Y . Sun 2271 (NIBRVP128343); Jangsu-gun, Gyenam-myeon, Mt. Jangansan, 19 June 2009, J. K . Ahn, S. J. Lee & Y. W. Lee CH 40006 (NIBRVP266477); Jangsu-gun, Gyenammyeon, Mt. Jangansan, 19 June 2009, J. K . Ahn, S. J. Lee & Y. W. Lee CH 40239 (NIBRVP266707); Jinan-gun, Jucheon-myeon, Daebul-ri, Mt. Unjangsan, without date, C. H . Kim & S. H. Lee 50051 (3 sheets, NIBRVP537859). Gyeongsangnam-do: Geochanggun, Buksang-myeon, Mt. Deogyusan hyangjeokbong-satgatgoljae, 31 May 2006, B. Y . Sun 1577 (4 sheets, NIBRVP119643). Note: The holotype is deposited in SKK.Published as part of Jang, Hyun-Do, Hyun, Chang-Woo, Ryu, Seah & Lee, Sang-Jun, 2022, Type specimens of vascular plants in the herbarium of the National Institute of Biological Resources (II), pp. 229-243 in Phytotaxa 539 (3) on page 237, DOI: 10.11646/phytotaxa.539.3.2, http://zenodo.org/record/636408

    5,7-dihydroxy-3,4,6-trimethoxyflavone inhibits the inflammatory effects induced by Bacteroides fragilis enterotoxin via dissociating the complex of heat shock protein 90 and I kappa B alpha and I kappa B kinase-gamma in intestinal epithelial cell culture

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    Enterotoxin produced by enterotoxigenic Bacteroides fragilis (BFT) has been associated with mucosal inflammation and diarrhoeal diseases. In this study, the anti-inflammatory molecular mechanism of 5,7-dihydroxy-3,4,6-trimethoxyflavone (eupatilin) was characterized in an HT-29 intestinal epithelial cell line stimulated with BFT. Pre-treatment of HT-29 cells with eupatilin decreased the production significantly of both interleukin (IL)-8 and prostaglandin E(2) induced by BFT in a dose-dependent manner. BFT-activated nuclear factor-kappaB (NF-kappa B) signals in HT-29 cells and pretreatment with eupatilin suppressed NF-kappa B activation that resulted in the significant inhibition of IL-8 and cyclo-oxygenase-2 expression. BFT-induced phosphorylation of both I kappa B alpha and I kappa B kinase (IKK) signals was prevented in eupatilin-pretreated HT-29 cells. Transfection of siRNA for IKK-alpha and IKK-beta decreased the production of IL-8 and prostaglandin E(2); however, the transfection of IKK-beta siRNA showed a more significant reduction of BFT-induced I kappa B alpha phosphorylation compared with that of IKK-alpha siRNA. In addition, herbimycin A, a specific inhibitor of heat shock protein 90 (Hsp90), decreased the BFT-induced activation of IKK and NF-kappa B, suggesting that Hsp90 is associated with a pathway of IKK-NF-kappa B-IL-8/cyclo-oxygenase-2 gene signalling. Furthermore, eupatilin dissociated the complex between Hsp90 and IKK-gamma in BFT-stimulated HT-29 cells. These results suggest that eupatilin can suppress the NF-kappa B signalling pathway by targeting the Hsp90-IKK-gamma complex in intestinal epithelial cells and may attenuate BFT-induced inflammatory responses.J. M. Kim and D. H. Lee contributed equally to this work. We thank Dr Martin F. Kagnoff and Dr Joseph A. DiDonato for providing the reporter gene plasmids and Sung-Hee Yang, Jung Sang Youn and Han Jin Lee for their expert technical assistance. This work was supported by a grant from Seoul R&BD Program and the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korea government (MOST) (R11-2008-044-01004-0)

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Patterns of Regional Failure after Pancreaticoduodenectomy in Patients with Distal Extrahepatic Cholangiocarcinoma: Suggestion of the Clinical Target Volume for Elective Nodal Irradiation

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    Aims: To evaluate the pattern of locoregional recurrence (LRR) after pancreaticoduodenectomy in patients with distal extrahepatic cholangiocarcinoma (DEHC) and to identify an optimal target volume for elective nodal irradiation. Materials and methods: We analysed the medical records of DEHC patients who underwent pancreaticoduodenectomy and had LRR between 1991 and 2015. Among these patients, 30 received adjuvant chemotherapy alone, 14 underwent radiotherapy with or without chemotherapy and 28 received no treatment. After reviewing computed tomography or magnetic resonance imaging scans, the sites of LRR were identified and mapped to the corresponding locations on the representative computed tomography images. Results: In total, 136 LRRs were identified in 72 patients from four institutions. Local recurrences were observed at 44 sites (32.4%): tumour bed in 15, choledochojejunostomy in 25 and pancreaticojejunostomy in four. Regional recurrences were observed at 92 sites (67.6%); the most common site was the portal vein area (n = 18), followed by the para-aortic area (n = 17). Based on the mapped plots of regional recurrence, a clinical target volume covering 90% of regional recurrences was generated using the appropriate margin for the vascular structures of the portal vein, celiac axis, superior mesenteric artery, left gastric artery and aorta. Conclusions: Given the pattern of LRR, we showed that the nodal clinical target volume based on vascular structures could appropriately cover high-risk regions of nodal involvement. These findings may help physicians construct a target volume in postoperative radiotherapy for DEHC patients undergoing pancreaticoduodenectomy. (C) 2021 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.N

    Near-complete teleportation of a superposed coherent state

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    ©2004 The American Physical Society URL: http://link.aps.org/abstract/PRA/v70/e032327 doi:10.1103/PhysRevA.70.032327 PACS: 03.67.Hk, 03.65.Ud, 42.50.-pThe four Bell-type entangled coherent states, \alpha]\-alpha]+/-alpha]\alpha] and \alpha]\alpha]+/-\-alpha]\alpha], can be discriminated with a high probability using only linear optical means, as long as \alpha\ is not too small. Based on this observation, we propose a simple scheme to almost completely teleport a superposed coherent state. The nonunitary transformation that is required to complete the teleportation can be achieved by embedding the receiver&apos;s field state in a larger Hilbert space consisting of the field and a single atom and performing a unitary transformation on this Hilbert space.This research was supported by Korea Research Foundation Grant No. KRF-2002-070-C00029.We wish to thank Dr. J. Kim and Dr. B. A. Nguyen of KIAS and Professor M. S. Kim and Dr. H. Jeong of Queens University, Belfast for helpful discussions

    Search for direct CP violation in D0→h−h+ modes using semileptonic B decays

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    A search for direct CP violation in D0 → h-h+ (where h = K or π) is presented using data corresponding to an integrated luminosity of 1.0 fb-1 collected in 2011 by LHCb in pp collisions at a centre-of-mass energy of 7 TeV. The analysis uses D0 mesons produced in inclusive semileptonic b-hadron decays to the D0μX final state, where the charge of the accompanying muon is used to tag the flavour of the D0 meson. The difference in the CP-violating asymmetries between the two decay channels is measured to be ΔACP = ACP(K-K+) - ACP(π-π+) = (0.49± 0.30 (stat) ± 0.14 (syst))%
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