637 research outputs found
Colophons as a Tool for Mapping the Literary History of Bali : Ida Pedanda Made Sidemen - Poet, Author and Scribe
No full textRubinstein Raechelle. Colophons as a Tool for Mapping the Literary History of Bali : Ida Pedanda Made Sidemen - Poet, Author and Scribe. In: Archipel, volume 52, 1996. pp. 173-191
Frequency of early vascular aging and associated risk factors among an adult population in Latin America : the OPTIMO study
No full textThe main objective was to estimate the frequency of early vascular aging (EVA) in a sample of subjects from Latin America, with emphasis in young adults. We included 1416 subjects from 12 countries in Latin America who provided information about lifestyle, cardiovascular risk factors (CVRF), and anthropometrics. We measured pulse wave velocity (PWV) as a marker of arterial stiffness, and blood pressure (BP) using an oscillometric device (Mobil-O-Graph). To determine the frequency of EVA, we used multiple linear regression to estimate each subject’s PWV expected for his/her age and systolic BP, and compared with observed values to obtain standardized residuals (z-scores). We defined EVA when z-score was ≥1.96. Finally, a multivariable logistic regression analysis was performed to determine baseline characteristics associated with EVA. Mean age was 49.9 ± 15.5 years, male gender was 50.3%. Mean PWV was 7.52 m/s (SD 1.97), mean systolic BP was 125.3 mmHg (SD 16.7) and mean diastolic BP was 78.9 mmHg (SD 12.2). The frequency of EVA was 5.7% in the total population, 9.8% in adults of 40 years or less and 18.7% in those 30 years or less. In these young adults, multiple logistic regression analyses demonstrated that dyslipidemia and hypertension showed an independent association with EVA, and smoking a borderline association (p = 0.07). In conclusion, the frequency of EVA in a sample from Latin America was around 6%, with higher rates in young adults. These results would support the search of CVRF and EVA during early adulthood
Médiateur de Santé/Pair et psychoéducation en santé mentale : une rencontre sous les auspices de l'innovation dans le soin
No full textThis article deals with the psycho-educational approach mobilised in the programme initiated by the World Health Organisation (WHO) through the action carried out by the Collaborating Centre for Mental Health Europe with the Health Mediator/Air Mediator programme (MSP). The analysis is carried out by the author, who has been a Health/Pair Mediator since the beginning of this programme, based on his experience in this type of position. An approach deployed with patients and families. A form of partnership in mental health developed in France for more than a decade.Cet article traite de l’approche psychoéducative mobilisée dans le programme initié par l’Organisation Mondiale de la Santé (OMS) à travers l’action menée par le Centre Collaborateur de santé mentale Europe (CCOMS) avec le programme Médiateur de Santé/Pair (MSP). L’analyse est menée par l’auteur qui a été médiateur de santé/Pair dès le début de ce programme sur la base de son expérience à ce type de poste. Une approche déployée auprès des patients et des familles. Une forme de partenariat en santé mentale développée en France depuis plus d’une décennie
Imaging with Kantorovich--Rubinstein Discrepancy
No full text© 2014 Society for Industrial and Applied Mathematics. We propose the use of the Kantorovich-Rubinstein norm from optimal transport in imaging problems. In particular, we discuss a variational regularization model endowed with a Kantorovich- Rubinstein discrepancy term and total variation regularization in the context of image denoising and cartoon-texture decomposition. We point out connections of this approach to several other recently proposed methods such as total generalized variation and norms capturing oscillating patterns. We also show that the respective optimization problem can be turned into a convex-concave saddle point problem with simple constraints and hence can be solved by standard tools. Numerical examples exhibit interesting features and favorable performance for denoising and cartoon-texture decomposition.This research was supported by King Abdullah University of Science and Technology (KAUST) award KUK-I1-007-43 and EPSRC first grant EP/J009539/1, "Sparse & Higher-order Image Restoration."The research of the first author was supported by Leverhulme Early Career Fellowship ECF-2013-436.The research of this author was supported by a Senescyt (Ecuadorian Ministry of Education, Science, and Technology) Prometeo fellowship
The State of Open Data: Histories and Horizons.
No full textA decade ago, open data was more or less just an idea, emerging as a rough point of consensus
for action among pro-democracy practitioners, internet entrepreneurs, open source advocates,
civic technology developers, and open knowledge campaigners. Calls for “open data now”
offered a powerful critique of the way in which governments and other institutions were hoarding
valuable data paid for by taxpayers – data that if made accessible, could be reused in a myriad of
different ways to bring social and economic benefits and democratic change.
Ten years on, open data is much more than just an idea. First, it was a movement, and then a
label applied to vast quantities of data from genomics and geospatial data to land registers,
contracting, and parliamentary voting. Today, it’s a term found on government portals, in global
policy documents, and in job descriptions. Thousands of businesses around the world owe their
existence or their growth to the release of open government data, and hundreds of civil society
organisations have embraced open data as a key element of their social change toolkit.
For a while, it may have been possible to identify a cohesive open data movement united by
shared interests, working simply to gain access to more data and establishing the principle that
government data should be open. However, as the movement has evolved, stakeholders have
turned their focus to linking data use to specific needs and to questions of how to quantify the
return on investment in advancing open data. Within this fast growing and organic open data
movement, an ever-increasing number of networks and communities of practice have become
more diverse, fluid, and cross-sectoral.
So what is the open data movement today? What has it achieved over the last decade?
Answering these questions is at the core of this publication. It is a collective effort to explore what
we can learn from the past, to identify how to build on the investments made to date, and to look
at how open data policy and practice have started to address challenges such as mainstreaming
and sectorisation.
Exploring these questions is not just important for historical purposes. It can yield important
insights on how best to move forward. This publication is also an invitation to identify the issues
that may sustain this broad coalition into the future. We believe that a deep reflection about the
movement, even a reflection on whatever cracks have appeared or on the gaps between promise
and reality, provides a vital opportunity to discuss where realignment and rethinking are needed.This collection of essays is the product of an 18-month journey that has brought together
almost 70 authors, supported by over 200 other contributors, to produce 37 short chapters on the
current state of open data from a range of different perspectives, offering the most comprehensive
attempt to explore the breadth and depth of the open data field to date
New mutation of Rubinstein-Taybi Syndrome
No full textIntrodução: O Síndrome de Rubinstein-Taybi (SRT) tem uma prevalência de 1:100000 – 125000 e deve-se a microdelec-
ção do cr16p13.3, mutação do gene CREBBP ou do gene EP300.
Caso clínico: ♀, 8 anos. Gestação normal, ao nascer apresentava polegares grandes, luxação e fusão da primeira falange
bilateralmente. Avaliada aos 3 anos por atraso global do desenvolvimento, perturbação da linguagem e comportamento
hipercinético. Apresentava microcefalia, estrabismo divergente, respiração oral, clinodactilia, escoliose e hipertricose. Da
investigação realizada destaca-se RMN CE com lesões encefaloclásticas no córtex temporal e insular bilateralmente e hi-
poacúsica esquerda minor. Mutação heterozigótica c2803c>T (p.Gln935X) no exão 15 do gene CREBBP, ausente nos pais.
Actualmente cumpre currículo individual, recebe terapia da fala e está medicada com metilfenidato e risperidona.
Comentários: O défice cognitivo e as alterações do exame objectivo sugeriram SRT. A mutação c2803c>T (p.Gln935X)
no gene CREBBP foi associada pela primeira vez a este síndrome
Exportações de carne bovina e infraestrutura de transporte rodoviária e portuária de 2001 a 2009: uma abordagem gravitacional
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico, Programa de Pós-Graduação em Economia, Florianópolis, 2011Para investigar a exportação de carne bovina das microrregiões brasileira a pesquisa utiliza o modelo gravitacional aumentado com correção de amostra e empresas heterogêneas de Helpman, Melitz e Rubinstein, 2008, (HMR), para somente uma commodity. A partir dos dados de exportação de 43 microrregiões, pelos portos de Paranaguá, Santos e Itajaí para Europa Ocidental, Leste Europeu e Oriente médio entre os anos de 2001 a 2009, montou-se um painel com 3.843 observações. Os coeficientes obtidos mostraram que tempo, custo e quantidade movimentada de contêineres nos portos são barreiras relevantes para as exportações brasileiras, assim como a infraestrutura rodoviária. Ademais, com investimentos devidamente planejados na ordem de R140 milhões em comércio de carne.To investigate the exportation of Brazilian micro-region#s beef (cattle meat) the study used the augmented gravity model with sample correction and heterogeneous firms of Helpman, Melitz and Rubinstein, 2008, (HMR), for only one commodity. Using a data from the exports of 43 micro-regions to the ports of Paranaguá, Santos and Itajaí to Western Europe, Eastern Europe and the Middle East between the years 2001 to 2009, a panel was set up with 3.843 observations. The coefficients showed that time, ship-in costs and quantity of containers traded in ports are important barriers to Brazilian exports as well as road infrastructure. Moreover properly planned investments of around R 140 million in meat trade
Optimization and sensitivity analysis of computer simulation models by the score function method
No full textExperimental Design;Simulation;Optimization;Queueing Theory
Międzynarodowy Konkurs Młodych Pianistów "Arthur Rubinstein in memoriam" w Bydgoszczy
No full textThe author presents the 20-year history of the Competition for Young Pianists ”Arthur Rubinstein in memoriam” in the background of the region’s music culture and development of secondary and higher music education. She recalls the concert of Arthur Rubinstein at the Pomeranian Philharmonic in Bydgoszcz in 1960, and a stay of Karol Szymanowski in Bydgoszcz in the years 1921 and 1922, indicating these events as significant inspirations for the creation of the competition. She describes the nine successive editions of the competition, its program-artistic form, and laureates. She indicates the specificity of the competition for young pianists before 21 years of age, which gives them a special opportunity for promotion and development of their talent through recitals, as well as radio and TV recordings
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