156,418 research outputs found
Additional dark G-band in the p-arm of chromosome 19 due to a paracentric inversion with a breakpoint in the pericentromeric heterochromatin
Paracentric inversions in chromosome 19 have rarely been described. Here we present an inv(19)(p11p13.1) with a breakpoint in the pericentromeric heterochromatin which leads to an additional dark G-band in the p-arm of chromosome 19. The rearranged chromosome segregated in two generations of a family without any phenotypic effects. A detailed characterization of the inv(19) by molecular cytogenetic techniques is presented. (C) 2001 Wiley-Liss, Inc
O. A. C. Review Volume XLVI Issue 5, February 1934
The focus of this issue is the preparation for College Royal and recognizing its tenth anniversary. This month's agricultural article is a report from the Dominion Parasite Laboratory on the biological control of pests. Other articles provide an account of the activities of a stage manager and the development of the field of home economics at Macdonald College in Quebec. Campus news addresses the success of the 1934 Conversazione, the commemorating of the sixtieth anniversary of the founding of O. A. C., the attendance at the Canadian Author Lecture, and the successful productions of "The Apple Cart" and "Iolanthe". The Macdonald Institute column comments on the Conversat and women's athletics activities in basketball and the rifle club. The Alumni Record supplies alumni updates.EditorialTen Years of the RoyalRamblings on the RoyalBlame it on the stage managerBiological control of insect pests in CanadaNot for girls onlyCollege lifeLiterary sectionO. A. C. sportsfolioAlumni recordMacdonald newsLetters to the editoradvertisin
Legislação urbanística e ocupação do espaço: o caso do Campeche
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Urbanismo, História e Arquitetura da cidadeO presente trabalho investiga a ocupação de um espaço da Ilha de Santa Catarina sob a ótica da legislação urbanística, buscando entender a ocupação urbana e a atuação ou não das leis. O estudo analisa o trecho sul do Campeche, distrito do município de Florianópolis localizado no sudeste da Ilha através dos aspectos ambientais preponderantes, suas legislações nas três esferas de competência, natureza jurídica e seu contexto espacial. A legislação, ao classificar a ocupação do espaço urbano de uma maneira geral, configura-se como instrumento que consolida uma proposta de moldagem da cidade e esta vai se concretizando a partir dessa interferência, não se configurando, portanto, somente como instrumento delimitador e ordenador do território, mas influenciando a maneira de viver dos habitantes. Com base na apreciação do Plano Diretor dos Balneários, lei que estabelece o zoneamento territorial dos balneários de Florianópolis fixa os objetivos, as diretrizes e as estratégias do desenvolvimento, verifica-se que inúmeras são as discrepâncias da realidade face à lei em vigor. A pesquisa permite constatar a veracidade de algumas premissas estabelecidas, como a de que este Plano Diretor tal qual se encontra atualmente, não cumpre com seus objetivos de modelação e ordenamento para a Ilha de Santa Catarina. Podemos afirmar, inclusive, que o plano juntamente com a omissão do Poder Público possibilitou o avanço de ocupações irregulares e ilegais, através de suas incoerências em relação a outras legislações e de seu próprio texto legal com seus anexos. The research investigates the occupation of a space in the Island of Santa Catarina on the light of urban legislation, trying to understand its urban occupation and the influence or not of the laws. The study addresses the south area of Campeche, a district of Florianópolis county, located in the Southeast of the Island through its main environmental aspects, its legislation in the three spheres of competence, its judicial nature, and its spatial context. Legislation, when classifying the occupation of urban space in a general way, configures itself as a tool that consolidates a moulding proposal for the city, and the city becomes concrete on the basis of such interference; hence it does not only configures itself as an instrument that delimitates and orders the territory but also influences the way of life of its inhabitants. On the basis of an appreciation of the Plano Diretor dos Balneários, a law that defines the territorial zoning of the beaches of Florianópolis, its objectives, goals and strategies of development, it is possible to identify that several are the discrepancies between the reality and the existing law. The study allows verifying the veracity of some established premises, such as that this Plano Diretor as it is nowadays, does not fulfil its moulding and ordering objectives for the Island of Santa Catarina. It can be said that indeed the plan, together with the omission of government, allowed the expansion of irregular and illegal occupations via its incoherencies in relation to other legislation and its own legal text with its annexes
Opposing Effects of Neuronal Activity on Structural Plasticity
The connectivity of the brain is continuously adjusted to new environmental influences by several activity-dependent adaptive processes. The most investigated adaptive mechanism is activity-dependent functional or synaptic plasticity regulating the transmission efficacy of existing synapses. Another important but less prominently discussed adaptive process is structural plasticity, which changes the connectivity by the formation and deletion of synapses. In this review, we show, based on experimental evidence, that structural plasticity can be classified similar to synaptic plasticity into two categories: (i) Hebbian structural plasticity, which leads to an increase (decrease) of the number of synapses during phases of high (low) neuronal activity and (ii) homeostatic structural plasticity, which balances these changes by removing and adding synapses. Furthermore, based on experimental and theoretical insights, we argue that each type of structural plasticity fulfills a different function. While Hebbian structural changes enhance memory lifetime, storage capacity, and memory robustness, homeostatic structural plasticity self-organizes the connectivity of the neural network to assure stability. However, the link between functional synaptic and structural plasticity as well as the detailed interactions between Hebbian and homeostatic structural plasticity are more complex. This implies even richer dynamics requiring further experimental and theoretical investigations
O. A. C. Review Volume XXXVI Issue 12, August 1924
This slim summer issue contains the address given by the agricultural section of the British Association for the Advancement of Science, and a report on the visit of this association to the O. A. C. Other articles include instructions on increasing strawberry production and a biography of the author John Masefield. The editorial comments on Rhodes Scholars. The Alumni column provides an update of alumni activities. This issue does not contain a Macdonald column.JoyPresent-day problems in crop productionAfter the strawberry harvestJohn MasefieldVisit of the Agricultural Section of the British Association for the Advancement of ScienceEditorialCollege lifeAlumniadvertisin
Stichomitra asymbatos Foreman 1968
<p> <i>Stichomitra asymbatos</i> Foreman, 1968 (Fig. 4I)</p> <p> <i>Stichomitra asymbatos</i> Foreman, 1968: 73, pl. 8, fig. 10a-c.</p> <p> <i>Stichomitra grandis</i> – Hollis 1997: 78, pl. 19, figs 1-4 and synonymy therein.</p> <p> <i>Stichomitra asymbatos</i> – Aumond <i>et al.</i> 2009: 200, fig.3I, J.</p> <p>FIGURED SPECIMEN. — ULVG-7326.</p> <p>MATERIAL. — Eight specimens (recovered with the hydrogen peroxide method); three specimens (recovered with the acetic acid method).</p> <p> OCCURRENCE. — Upper Maastrichtian of California (Foreman 1968); Late Campanian-Maastrichtian to Early Paleocene of New Zealand (Hollis 1997); Maastrichtian of Caribbean Sea (Aumond <i>et al.</i> 2009).</p>Published as part of <i>Kochhann, Karlos G. D., Baecker-Fauth, Simone & Fauth, Gerson, 2013, Late Maastrichtian Radiolaria from ODP Leg 165 - Site 999 B, Colombian Basin, pp. 5-20 in Geodiversitas 35 (1)</i> on page 12, DOI: 10.5252/g2013n1a1, <a href="http://zenodo.org/record/4538016">http://zenodo.org/record/4538016</a>
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
The prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
The Thursday Murder Club: Launching a megabrand author - a publishing case study
In 2020, the Christmas book charts in the UK made headlines: Barack Obama’s eagerly awaited autobiography, The Promised Land, was beaten to the top spot by The Thursday Murder Club by Richard Osman, a debut cosy crime novel set in a retirement village. Not only did Osman’s book beat the former US president’s expected bestseller, it also broke records, becoming the fastest-selling debut crime novel of all time. Although Osman has a certain level of fame in the UK from his TV appearances on shows such as Pointless, his celebrity status does not entirely explain the novel’s huge sales. This article tracks the acquisition, publication, and promotion journey of The Thursday Murder Club in order to understand the industry and cultural context of its success and to interrogate the role of celebrity in the creation of author brands. The findings suggest that the unexpected scale of the success of the book owed to a number of factors, including in-depth editing by the novel’s agent, editor, and author to tighten up the plot, an extensive and strategic promotional campaign, the pandemic (which drove interest in the book’s genre and themes), and the quality of the writing. We find that the book’s success was accentuated by Osman’s celebrity status rather than being entirely reliant on it. This research adds to the growing scholarship on celebrity authorship by means of an in-depth case study and provides insight into the processes behind publishing a ‘celebrity’ book and launching a megabrand author
A Theme Analysis of Experiences Reported by Adult Children of Alcoholics in Online Support Forums
Growing up with an alcoholic parent can have a lasting effect on children and contribute to a variety of challenging outcomes in adulthood. This study identified the various experiences that adult children of alcoholics discuss with their peers in online support groups. Trained coders conducted a thematic analysis of 504 message board posts collected over a period of 60 days from three different online support groups to identify issues that children of alcoholics face in adulthood. Seven themes emerged from the analysis: a) empowerment through support, b) interference of parent in adulthood, c) connection to inner child and need to re-parent, d) low self-esteem and insecurity, e) anger and resentment, f) romantic relationship problems, and g) problems communicating. The results of this study provide insight into the issues that adult children of alcoholics need to address as part of their own recovery and suggest avenues of exploration for practitioners who work with high risk families.Peer reviewe
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