408 research outputs found
Automatic determination of the P/V relationship of the respiratory system during mechanical ventilation
No full textPressure-volume curve of the respiratory system in ARDS: "occlusion" vs "automated low flow inflation"."
No full textDrug Effect Unveils Inter-head Cooperativity and Strain-dependent ADP Release in Fast Skeletal Actomyosin
No full textAmrinone is a bipyridine compound with characteristic effects on the force-velocity relationship of fast skeletal muscle, including a reduction in the maximum shortening velocity and increased maximum isometric force. Here we performed experiments to elucidate the molecular mechanisms for these effects, with the additional aim to gain insight into the molecular mechanisms underlying the force-velocity relationship. In vitro motility assays established that amrinone reduces the sliding velocity of heavy meromyosin-propelled actin filaments by 30% at different ionic strengths of the assay solution. Stopped-flow studies of myofibrils, heavy meromyosin and myosin subfragment 1, showed that the effects on sliding speed were not because of a reduced rate of ATP-induced actomyosin dissociation because the rate of this process was increased by amrinone. Moreover, optical tweezers studies could not detect any amrinone-induced changes in the working stroke length. In contrast, the ADP affinity of acto-heavy meromyosin was increased about 2-fold by 1 mm amrinone. Similar effects were not observed for acto-subfragment 1. Together with the other findings, this suggests that the amrinone-induced reduction in sliding velocity is attributed to inhibition of a strain-dependent ADP release step. Modeling results show that such an effect may account for the amrinone-induced changes of the force-velocity relationship. The data emphasize the importance of the rate of a strain-dependent ADP release step in influencing the maximum sliding velocity in fast skeletal muscle. The data also lead us to discuss the possible importance of cooperative interactions between the two myosin heads in muscle contraction
Automatic determination of the pressure-curve of the respiratory system during mechanical ventilation."
No full textAn in vitro comparison between two methods of electrical resistance measurement for occlusal caries detection
No full textBecause of different measurement techniques and the easier design of the CRM prototype, this in vitro study aimed to compare the diagnostic performance and reproducibility of two electrical methods (Electronic Caries Monitor III, ECM and Cariometer 800, CRM) for occlusal caries detection, and to evaluate the effect of staining/ discoloration of fissures on diagnostic performance. Hundred and seventeen third molars with no apparent occlusal cavitation were selected. Six examiners inspected all specimens independently, using the CRM, and a subgroup of 4 using the ECM. Histological validation using a stereomicroscope was performed after hemisectioning. Intra- and interexaminer reproducibility was assessed by Lin's concordance correlation coefficient (CCC) and Bland and Altman analysis. Diagnostic performance parameters included sensitivity (SE), specificity (SP) and area under the ROC curve (A(z)). The CCC yielded an intra- and interexaminer reproducibility of 0.69/0.62 (ECM) and of 0.79/0.74 (CRM). The mean intra- and interexaminer 95% range of measurements (range between Bland and Altman limits of agreement) given in percentages of the instrument reading were 67%/65% for the ECM and 28%/33% for the CRM. A(z) at the D3-4 level was 0.74 (ECM) and 0.78 (CRM). The CRM showed at least equivalent diagnostic performance to the ECM. However, improvement is still desirable. Diagnostic performance appeared to be enhanced in discolored lesions; however, this may be related to sample lesion distribution characteristics. Copyright (C) 2006 S. Karger AG, Basel
A G4MP2 theoretical study on the gas phase enthalpies of formation for various polycyclic aromatic hydrocarbons (PAHs) and other C~10~ through C~20~ unsaturated hydrocarbons
No full textGas phase enthalpies of formation at 298.15 and 1 atm (Δ~f~H~(g),298K~) were calculated using the atomization approach at the G4MP2 composite method level of theory for 86 polyaromatic hydrocarbons (PAHs) and other C~10~ through C~20~ unsaturated hydrocarbons. Where available, good agreement with prior experimental data and/or high level theoretical estimates was obtained. Linear regressions between semiempirical MNDO, MNDO-d, AM1, PM3, RM1, and PM6 estimated Δ~f~H~(g),298K~ and the corresponding G4MP2 values were employed to obtain G4MP2 corrected semiempirical Δ~f~H~(g),298K~ for a suite of 156 C~11~ through C~42~ unsaturated hydrocarbons and PAHs
Intergenerational affectionate communication: conceptions of young adults toward their grandparent
No full textInternational audienceTheoretical background Methods Results Discussion References Grandparent (GP)-Grandchild (GC) relationship is usually meaningful for both generations and of strong influence on each other lives. GP positively influence their GC's development and well-being (Mansson, 2015). Previous research underlined the influence of the frequency of contact, geographic distance, grandparent's age, grandparent's health as well as many other variables on GP-GC closeness. Notwithstanding, few studies have been conducted on the influence of communication, and specifically affectionate communication on GP-GC closeness. While creating the Grandchildren Received Affection Scale, Mansson (2013) found that GC received four types of affectionate communication from their GP: love and esteem, caring, memories and humor, and celebratory affection. Those four types of affectionate communication constitute the four dimensions of this scale. Mansson, Floyd, & Soliz (2017) found that received affection from GP is associated positively with GCs' perceptions of their GP and their GP-GC relationship as well as with GC's perceived shared family identity with their grandparent but not with celebratory affection and shared family identity A sample of young adults students between 18 and 25 years old (N= 285) completed the French Translation of the Grandchildren Received Affection Scale (GRAS) (Mansson, 2013) as well as demographics and four complementary scales: Ideal Grandparent Scale (Mansson, 2015), Parental Encouragement Scale (Soliz & Harwood, 2006), Shared Family Identity Scale (Soliz & Harwood, 2006), and the CES-D (Radloff, 1977) while thinking about the grandparent with the closest day of birth. The GRAS is composed of 17 items split in 4 dimensions (Love and esteem, caring, memories and humor, celebratory affection)
Angle Resolved Photoemission from Nd1.85Ce0.15CuO4 using High Energy Photons: A Fermi Surface Investigation
No full textWe have performed an angle resolved photoemission study on a single crystal of the optimally
electron doped (n-type) cuprate superconductor Nd2xCexCuO4 (x 0:15) at a photon energy of 400 eV.
The Fermi surface is mapped out and is, in agreement with earlier measurements, of hole-type with the
expected Luttinger volume. However, comparing with previous low energy measurements, we observe a
different Fermi surface shape and a different distribution of spectral intensity around the Fermi surface
contour. The observed Fermi surface shape indicates a stronger electron correlation in the bulk as
compared to the surface
Tourists' filmic representations on YouTube: A case study analysis of two mediatized visits to the Mursi in Ethiopia
No full textContains fulltext :
221806.pdf (Publisher’s version ) (Open Access)Much primitivist tourism is based on the gap between the ahistorical wild Other and the modern civilized Self (Stasch, 2014). In this chapter, we focus on what we see as an emergent practice of (neo-colonial) visual consumption: filmic representations by tourists and semi-professional travellers of their visits to 'primitive' places, which they subsequently post on social media. As case studies, we have selected two YouTubevideos on Ethiopia's Mursi that are, despite obvious differences, similar enough to allow for a systematic comparison. In choosing the Mursi, often presented as an extreme example of cultural alterity because of their characteristic lip plates, we continue where the provocative documentary Framing the Other (Kok & Timmers, 2011), which had its focus on Dutch tourists visiting the Mursi, left off. The authors' main goal is to understand the contemporary nature of cultural consumption and production and, in their wake, the power differentials underlying this growing virtual domain of representations. Using theory and analytical approaches from both cultural studies and anthropology, we look at historical tropes employed to frame self and other, and consider the possible consequences, ethical and otherwise, of this type of mediatization of tourist encounters
- …
