2,517 research outputs found
A 1H NMR study on the interaction of aminoxyl paramagnetic probes with unfolded peptides
No full textThe use of soluble spin labels to filter out the cross peaks of outer proton nuclei in 2D NMR spectra has been proposed as a general method to obtain structural information for complex molecules. Here the paramagnetic effects observed on backbone protons of an unfolded 27 amino acid peptide are discussed. The lack of any differential intensity change of the NH-Halpha cross-peaks in TOCSY spectra is suggested as an additional general criterion for the identification of unfolded structures
Education and Training in St.Lucia: A Partially Annotated Bibliography
No full textThis bibliography on “Education and Training in St. Lucia” has been specifically prepared for the UWI School of Continuing Studies’ St. Lucia Country Conference. An attempt has been made to be as comprehensive as possible, but because of the weak bibliographical coverage of the literature of the region, important items may have been omitted. This is especially true for policy documents emanating from official sources. It covers all aspects of education and training in St.Lucia including distance education, educational finance,health and family life education and educational reform
Columbus Square, St. Lucia
No full textLandscape, black & white, 4 x 6 in.No. 18.
Columbus Square, St. Lucia.
Columbus Square, St. Lucia, located in the heart of the capital city, Castries was formerly the site of the Place D’Armes, which was renamed Promenade Square before being renamed the Columbus Square. The Square is currently named after a St. Lucian author Derek Walcott. This spot also pays respect to residents who lost their lives in battle.
On the Postcard; “Columbus Square, St. Lucia.” people can be seen congregating in the Square under the trees.
Information at the back of the Post Card:
Union Postale Universelle
Sarah Cameron, 2013. Footprint Focus. St Lucia & Dominica with Fort-de-France
The language of the cataloguer (part 1). The author
No full textThe paper analyses the evolution of the language of cataloguing, focusing on the concept of authorship. It evaluates cataloguing principles, rules and theory, from Cutter to ICP 2016, in order to study the modification of the idea of author in cataloguing and the emerging importance of non-authorial responsibilities as access points for the organization of catalogues
The causes and the effects of the deficiency in the Pre-Legislative and Legislative scrutiny processes in St. Lucia
No full textThis dissertation argues that there is a significant deficiency in the pre-legislative and legislative scrutiny processes in St. Lucia, caused by the failure of Parliament to utilize the Standing Orders in the manner in which they were intended and develop and follow a more systematic scrutiny process. The author explains how this has hindered St. Lucia’s ability to gain more benefit from the legislative process and improve the quality of legislation produced with less likelihood of amendments
Central nervous system trans-synaptic effects of acute axonal injury : a 1-H magnetic resonance spectroscopy study
No full textN-acetylaspartate (NAA) has previously been proposed as a neuronal marker. 1H magnetic resonance spectroscopy (MRS) is able to detect NAA in brain, and decreases of NAA have been documented after brain injury. The reason for this decrease is not fully understood and neuron loss damage and "dysfunction" have all been proposed. It is hypothesized that acute central nervous system (CNS) deafferentation causes a trans-synaptic NAA decrease and that high resolution 1H MRS is able to detect such a decrease. To test this hypothesis, an experimental model was used in which axonal lesions were obtained by stretch injury in guinea pig right optic nerve (95-99% crossed fibers). The trans-synaptic concentration of NAA, total creatine (Cr), and the NAA/Cr ratio in lateral geniculate bodies (LGB) and superior colliculi (SC) sample extracts were measured 72 h later by high resolution 1H MRS. In the left LGB/SC, which is where right optic nerve fibers project, reductions of NAA and NAA/Cr were found whereas Cr levels were normal. NAA, NAA/Cr, and Cr values were all normal in the right LGB/SC. Histology and EM findings revealed no abnormalities. At 7 days, left LGB/SC NAA and NAA/Cr values were in the normal range. It was concluded that 1) acute deafferentation in the CNS causes a trans-synaptic decrease of NAA levels that can be detected by 1H MRS and 2) NAA decrease may be due to changes of NAA metabolism caused by functional neuronal inactivity rather than neuronal loss, injury or "dysfunction." 1H MRS is a potential tool for the study of functional effect of CNS lesions in vivo
Export Processing in the Caribbean: Lessons from Four Case Studies
No full textThe author reviews case studies of four Caribbean countries-the Dominican Republic, Jamaica, Saint Lucia and Trinidad-and briefly discusses an African country, Mauritius. He compares labour legislation, nationality of investors, technology transfer, and linkages with the rest of the economy. Of these five cases, only Trinidad failed to develop a significant export processing sector. Explanations rooted in government policy are suggested for this result. United Nations ECLAC Working Paper No. 42 (September 1996).export processing zones, export promotion, Dominincan Republic, Saint Lucia, Jamaica, Trinidad and Tobago, Mauritius, transnational corporations
Selective step-growth phenol-aldehyde polymerization. 4. Regio-, enantio-, and diastereo-controlled entry to chiral nonracemic all-ortho novolacs
No full textSolution conformation of tuftsin
No full textAbstract
Monomeric bovine seminal ribonuclease (mBS-RNase), the subunit of dimeric bovine seminal ribonuclease (BS-RNase), is an unusual monomer: for its structural stability, its catalytic activity, which is even higher than that of the parent dimeric enzyme, and for its role as an intermediate in the refolding of dimeric BS-RNase. Here we present the proton NMR assignment and secondary-structure determination of mBS-RNase, with a comparison of its structure to the structure of its parent protein, and to the structure of RNase A, a homologue with more than 80% identity in amino acid sequence. Proton NMR assignment was performed using a computer-assisted procedure, through a partially automated analysis of homonuclear three-dimensional spectra [Oschkinat, H., Holak, T. A. & Cieslar, C. (1991) Biopolymers 31, 699-712]. The secondary structures of mBS-RNase, of the A chain of dimeric BS-RNase, and of RNase A, are found to be similar. Significant differences are found instead, between mBS-RNase and RNase A in the more flexible stretches of the molecule, where a higher number of substitutions is present. Furthermore, a preliminary tertiary-structure model is reported, showing that the overall folding of mBS-RNase is closer to that of RNase A rather than that of (dimeric) BS-RNase
Séquence 3, La rencontre entre Ivaldo et Lucia, raconté par Ivaldo
No full textCette séquence fait partie du corpus vidéo de Langue des Signes Emergentes utilisé lors de la thèse d'Ivani Fusellier-Souza : le locuteur Ivaldo raconte avec Lucia leur première rencontre.00:00:00>00:00:14 Lucia demande à Ivaldo de raconter leur rencontre, ou du moins la première fois qu'il l'a vu dans la rue. 00:00:14>00:00:18 Ivaldo raconte que Lucia passait dans la rue et qu'il l'a regardé marcher. 00:00:18>00:00:20 Lucia lui rappelle qu'elle marchait dans la rue et avait un air hautain. 00:00:20>00:00:24 Ivaldo raconte qu'il lui a offert une glace qu'elle a mangée. 00:00:24>00:00:26 Lucia lui dit qu'il la regardait de loin. 00:00:26>00:00:31 Ivaldo raconte qu'il l'a vu passée et qu'il lui a offert une glace qu'elle a accepté. 00:00:31> 00:00:42 Lucia se rappelle qu'il lui a offert une glace. 00:00:42>00:00:52 Ivaldo demande à son fils de ne pas passer devant la caméra. 00:00:52>00:00:58 Lucia lui rappelle comment elle était belle avec ses cheveux longs. 00:00:58>00:01:20 Ivaldo raconte qu'il n'aimait pas ses cheveux longs, qu'il préfère Lucia avec des cheveux courts, et qu'elle a bien fait de les couper. 00:01:20>00:01:23 Lucia raconte qu'après ils se sont mariés. 00:01:23>00:01:32 Ivaldo dit qu'ils se sont mariés à Fortaleza
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