390,373 research outputs found
Molecular structure of highly excited resonant states in Mg-24 and the corresponding Be-8+O-16 and C-12+C-12 decays
No full textExotic Be-8 and C-12 decays from high-lying resonances in Mg-24 are analyzed in terms of a cluster model. The calculated quantities agree well with the corresponding experimental data. It is found that the calculated decay widths are very sensitive to the angular momentum carried by the outgoing cluster. It is shown that this property makes cluster decay a powerful tool to determine the spin as well as the molecular structures of the resonances.Physics, NuclearSCI(E)7ARTICLE5null8
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
B -> eta K-c(eta ' K-c) decays in QCD factorization
No full textWe study the exclusive decays of the B meson into pseudoscalar charmonium states eta(c) and eta(c)' within the QCD factorization approach and find that the non-factorizable corrections to naive factorization are infrared safe at leading-twist order. The spectator interactions arising from the kaon twist-3 effects are formally power suppressed but chirally and logarithmically enhanced. An important improvement by including the O(alpha(s)) corrections is the cancellation of the renormalization scale mu dependence of the decay amplitude. However, the calculated decay rates are too small to accommodate the experimental data. On the other hand, we compare the theoretical calculations for B meson decays to J/psi, psi', eta(c) and eta'(c), and find that the predicted relative decay rates of these four states are approximately compatible with the experimental data.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000223097800007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Physics, Particles & FieldsSCI(E)17ARTICLE3365-3703
History sketch 157th Engineer (C) Bn.
No full textThis is a historical description of the 157th Engineer (C) Battalion written from memory by author. Notes are not attached as described on last page of document
Induction of c-Cbl contributes to anti-cancer effects of HDAC inhibitor in lung cancer
No full textHere we found loss of c-Cbl, an E3 ligase, expression in non-small cell lung cancer (NSCLC) compared with its adjacent normal tissue in patient specimens. HDAC inhibition by WJ or knockdown of HDAC 1, HDAC2, HDAC3 or HDAC6 all induced c-Cbl. Ectopic expression of c-Cbl induced decreased EGFR, inhibited growth in NSCLC cells. Knockdown of EGFR inhibited NSCLC growth. Mutation of EGFR at Y1045 decreased WJ-induced growth inhibition as well as in vivo anti-cancer effect and EGFR degradation mediated by WJ. Time-lapse confocal analysis showed co-localization of c-Cbl and EGFR after WJ treatment. Furthermore, WJ inhibited lung tumor growth through c-Cbl induction in orthotopic and tail vein injected models. C-Cbl up-regulation induced by HDACi is a potential strategy for NSCLC treatment
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
Full text linkThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
Matematı?k o?g?retmenlerı?nı?n c?okgenler konusundakı? matematı?ksel formu?ller ve o?zellı?klere ı?lı?s?kı?n kavramsal anlamaları
No full textMatematiksel formu?ller, nicelikler arasındaki ilis?kiyi go?stermeye yarayan kısa cebirsel ifadelerdir Matematik derslerinde c?ok sayıda formu?l oldug?u ic?in bu ifadeleri ezberlemek oldukc?a zordur. Matematik dersinin o?g?retilmesinde is?lemsel bilginin o?tesinde kavramsal bilginin o?g?retilmesi o?nem arz etmektedir. Dolasıyla bu formu?llerin ve kuralların o?g?renciler ve o?g?retmenler tarafından anlas?ılması gerekmektedir. C?u?nku? formu?lleri ve kuralları ezberleyen o?g?renciler, rutin olmayan problemlerde problemi c?o?zebilmek ic?in eles?tirel du?s?u?nmeyebilir. Bu bakımdan, matematiksel kurallar ve formu?ller o?g?retilirken onları anlama ve akıl yu?ru?tme u?zerine odaklanılmalıdır. Bu su?rec?te o?nemli bir etken olan o?g?retmenlerin rolu? go?z o?nu?ne alınırsa, hic? s?u?phesiz ki o?g?retmenlerin matematiksel formu?ller ve kurallarla ilgili kavramsal anlamalarının aras?tırılmasının gerekli oldug?u du?s?u?nu?lmektedir. O?zellikle de matematik dersi o?g?retim programlarında o?g?renme alanlarından biri olan geometride c?ok sayıda formu?l ve kural yer almaktadır. Bu aras?tırmanın amacı, matematik o?g?retmenlerinin konveks c?okgenler konusunda yer alan matematiksel formu?ller ve o?zelliklere ilis?kin kavramsal anlamalarını incelemektir. Bu amac? kapsamında aras?tırmaya 6 matematik o?g?retmeni (2 Bayan, 4 Bay) katılmıs?tır. Amac?lı o?rnekleme yo?ntemi ile sec?ilen o?g?retmenlerden u?c?u? sosyo-ekonomik du?zey bakımından orta du?zeyde olan bir devlet ortaokulunda aktif olarak c?alıs?ırken, geriye kalan u?c? o?g?retmen de sosyo-ekonomik du?zeyi orta du?zey olan bir lisede aktif olarak c?alıs?maktadır. Aras?tırma modeli olarak nitel yo?ntemlerden durum c?alıs?ması yo?ntemi kullanılmıs?tır. Veri toplama aracı olarak, geometri o?g?renme alanında dıs?bu?key c?okgenlerde sıklıkla kullanılan (n kenarlı bir konveks c?okgenin ic? ac?ılarının o?lc?u?leri toplamı olması, n kenarlı bir konveks c?okgenin tu?m ko?s?egenlerinin sayısının ) matematiksel formu?ller ve o?zelliklere ilis?kin 6 sorudan olus?an go?ru?s?me formu hazırlanmıs?tır. Klinik go?ru?s?me teknig?i ile toplanan veriler, nitel aras?tırma teknikleri ile analiz edilmis?tir. Aras?tırma sonunda, o?g?retmenlerin bazılarının c?okgenlerle ilgili formu?llerin ve o?zelliklerin altında yatan mantıksal gerekc?eyi ifade edebildikleri, bazılarının ise formu?lleri ezbere bildikleri go?ru?lmu?s?tu?r. Ayrıca kenar sayısı olan bir konveks c?okgenin c?izilebilmesi ic?in tane elemanın bilinmesi gerektig?i konusunda hemen hemen tu?m o?g?retmenlerin ac?ıklama yapmakta zorlandıkları tespit edilmis?tir
Microscopic mechanism of charged-particle radioactivity and generalization of the Geiger-Nuttall law
No full textA linear relation for charged-particle emissions is presented starting from the microscopic mechanism of the radioactive decay. It relates the logarithms of the decay half-lives with two variables, called. chi' and. rho', which depend upon the Q values of the outgoing clusters as well as the masses and charges of the nuclei involved in the decay. This relation explains well all known cluster decays. It is found to be a generalization of the Geiger-Nuttall law in a radioactivity, and therefore we call it the universal decay law. Predictions of the most likely emissions of various clusters are presented by applying the law over the whole nuclear chart. It is seen that the decays of heavier clusters with nonequal proton and neutron numbers are mostly located in the trans-lead region. The emissions of clusters with equal protons and neutrons, like (12)C and (16)O, are possible in some neutron-deficient nuclei with Z >= 54.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271352900039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Physics, NuclearSCI(E)51ARTICLE4null8
Cystatin C and Long-Term Mortality among Subjects with Normal Creatinine- Based Estimated Glomerular Filtration Rates
No full textObjectives The objective was to test the association of cystatin C (Cys-C ) with long-term mortality risk in the subjects with normal creatinine- based estimated glomerular filtration rates (eGFR). Background Cys-C has been proposed as a sensitive indicator of renal dysfunction that is associated with cardiovascular events. The predictive value of Cys-C for mortality risk (both cardiovascular and noncardiovascular) and its utility among persons with normal kidney function remains unclear. Methods The analysis included 2,990 subjects over 40 years of age with normal eGFR who participated in NHANES III (Third National Health and Nutrition Examination Survey). Normal eGFR was defined by Modification of Diet in Renal Disease (MDRD) equation >= 60 ml/min/1.73 m(2). Serum Cys-C was categorized as high, medium, or low. In 1 analysis, the high and low groups were the top and bottom 10%, and in the second analysis, they were the upper and lower thirds. All-cause and cause- specific mortality were obtained from the NHANES III-linked follow-up file through December 31, 2006. Multivariate Cox regression models were applied to assess the association of interest. Results Within an average of 13.7 years follow-up , 488 cardiovascular and 719 noncardiovascular deaths occurred. When the first and last deciles were compared, the relative risks were all increased statistically as follows: allcause, 4.36 (95% confidence interval [CI]: 2.52 to 7.82) ; cardiovascular, 7.44 (95% CI: 3.06 to 18.1) ; cancer, 2.45 (95% CI: 0.85 to 7.04); and noncardiovascular 3.15 (95% CI: 1.53 to 6.49) mortalities. Relative risks all moderated to lower values when the comparisons were expanded to include the upper and lower thirds. Similar associations were still present when Cys-C was modeled on a continuous scale, suggesting a linear relationship between Cys-C and mortality outcomes. Conclusions Serum Cys-C is prognostic of long- term mortality in the subjects with relatively normal renal function, independent of MDRD eGFR and albuminuria
O. A. C. Review Volume XLVI Issue 5, February 1934
No full textThe focus of this issue is the preparation for College Royal and recognizing its tenth anniversary. This month's agricultural article is a report from the Dominion Parasite Laboratory on the biological control of pests. Other articles provide an account of the activities of a stage manager and the development of the field of home economics at Macdonald College in Quebec. Campus news addresses the success of the 1934 Conversazione, the commemorating of the sixtieth anniversary of the founding of O. A. C., the attendance at the Canadian Author Lecture, and the successful productions of "The Apple Cart" and "Iolanthe". The Macdonald Institute column comments on the Conversat and women's athletics activities in basketball and the rifle club. The Alumni Record supplies alumni updates.EditorialTen Years of the RoyalRamblings on the RoyalBlame it on the stage managerBiological control of insect pests in CanadaNot for girls onlyCollege lifeLiterary sectionO. A. C. sportsfolioAlumni recordMacdonald newsLetters to the editoradvertisin
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