129,479 research outputs found
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
Full text linkThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
Intersystem soft handover for converged DVB-H and UMTS networks
Full text linkDigital video broadcasting for handhelds (DVB-H) is the standard for broadcasting Internet Protocol (IP) data services to mobile portable devices. To provide interactive services for DVB-H, the Universal Mobile Telecommunications System (UMTS) can be used as a terrestrial interaction channel for the unidirectional DVB-H network. The converged DVB-H and UMTS network can be used to address the congestion problems due to the limited multimedia channel accesses of the UMTS network. In the converged network, intersystem soft handover between DVB-H and UMTS is needed for an optimum radio resource allocation, which reduces network operation cost while providing the required quality of service. This paper deals with the intersystem soft handover between DVB-H and UMTS in such a converged network. The converged network structure is presented. A novel soft handover scheme is proposed and evaluated. After considering the network operation cost, the performance tradeoff between the network quality of service and the network operation cost for the intersystem soft handover in the converged network is modeled using a stochastic tree and analyzed using a numerical simulation. The results show that the proposed algorithm is feasible and has the potential to be used for implementation in the real environment
Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′
Full text linkFirst evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
Full text linkIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Penerjemahan Adaptasi Cerita Anak Al Hud-Hud Yamtaliku T?j?n Karya Abdul Tawwab Yusuf
No full textPenelitian ini bertujuan untuk mengevaluasi penerapan metode adaptasi dalam penerjemahan bahasa Arab ke dalam bahasa Indonesia pada buku Al Hud-Hud Yamtaliku T?j?n. Metode yang digunakan adalah metode kualitatif dengan pendekatan deskriptif yang berlandaskan pada teks buku AL Hud-Hud Yamtaliku T?j?n sebagai objek penelitian. Hasil penelitian menujukkan bahwa penerapan metode penerjemahan adaptasi pada cerita anak Al Hud-Hud Yamtaliku T?j?nefektif untuk dilakukan. Dalam menerjemahkan cerita anak juga menggunakan strategi penerjemahan seperti penambahan (ziyadah) sebanyak 9, strategi pengurangan (hadzf) sebanyak 10, dan strategi mengganti (tabdil) sebanyak 10. Sebanyak 10 data tentang penelitian ini memberikan kontribusi dalam memahami proses penerjemahan dan strategi penerjemahan adaptasi pada cerita anak Al HudHud Yamtaliku T?j?n karya Abdul Tawwab Yusuf .xv, 53 hlm, 25 c
Penerjemahan Adaptasi Cerita Anak Al Hud-Hud Yamtaliku T?j?n Karya Abdul Tawwab Yusuf
No full textPenelitian ini bertujuan untuk mengevaluasi penerapan metode adaptasi dalam penerjemahan bahasa Arab ke dalam bahasa Indonesia pada buku Al Hud-Hud Yamtaliku T?j?n. Metode yang digunakan adalah metode kualitatif dengan pendekatan deskriptif yang berlandaskan pada teks buku AL Hud-Hud Yamtaliku T?j?n sebagai objek penelitian. Hasil penelitian menujukkan bahwa penerapan metode penerjemahan adaptasi pada cerita anak Al Hud-Hud Yamtaliku T?j?nefektif untuk dilakukan. Dalam menerjemahkan cerita anak juga menggunakan strategi penerjemahan seperti penambahan (ziyadah) sebanyak 9, strategi pengurangan (hadzf) sebanyak 10, dan strategi mengganti (tabdil) sebanyak 10. Sebanyak 10 data tentang penelitian ini memberikan kontribusi dalam memahami proses penerjemahan dan strategi penerjemahan adaptasi pada cerita anak Al HudHud Yamtaliku T?j?n karya Abdul Tawwab Yusuf .xv, 53 hlm, 25 c
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
Measurement of J/Ψ production in pp collisions at √s=7 TeV
Full text linkThe production of J/psi mesons in proton-proton collisions at root s = 7 TeV is studied with the LHCb detector at the LHC. The differential cross-section for prompt J/psi production is measured as a function of the J/psi transverse momentum p(T) and rapidity y in the fiducial region p(T) is an element of [0; 14] GeV/c and y is an element of [2.0; 4.5]. The differential cross-section and fraction of J/psi from b-hadron decays are also measured in the same p(T) and y ranges. The analysis is based on a data sample corresponding to an integrated luminosity of 5.2 pb(-1). The measured cross-sections integrated over the fiducial region are 10.52 +/- 0.04 +/- 1.40(-2.20)(+1.64) mu b for prompt J/psi production and 1.14 +/- 0.01 +/- 0.16 mu b for J/psi from b-hadron decays, where the first uncertainty is statistical and the second systematic. The prompt J/psi production cross-section is obtained assuming no J/psi polarisation and the third error indicates the acceptance uncertainty due to this assumption
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