5,010 research outputs found

    Natalia LL - artystka neoawangardowa

    Get PDF
    The paper shows Natalia Lach-Lachowicz (Natalia LL) as a neo avant-garde artist whose works in a specific maximalistic way are very close to the main currents of avant-garde trends: new mediality (photography), minimalism, conceptualism, performance, bodyart, pop-art, and feminist art. The author of the article concentrates mainly on the mutual influences of conceptualism, consumptionism, and feminism in Natalia LL’s works and pays attention to the emancipatory potential of her works of the seventies and the eighties

    Author response

    Get PDF
    Detecting pathogens and mounting immune responses upon infection is crucial for animal health. However, these responses come at a high metabolic price (McKean and Lazzaro, 2011, Kominsky et al., 2010), and avoiding pathogens before infection may be advantageous. The bacterial endotoxins lipopolysaccharides (LPS) are important immune system infection cues (Abbas et al., 2014), but it remains unknown whether animals possess sensory mechanisms to detect them prior to infection. Here we show that Drosophila melanogaster display strong aversive responses to LPS and that gustatory neurons expressing Gr66a bitter receptors mediate avoidance of LPS in feeding and egg laying assays. We found the expression of the chemosensory cation channel dTRPA1 in these cells to be necessary and sufficient for LPS avoidance. Furthermore, LPS stimulates Drosophila neurons in a TRPA1-dependent manner and activates exogenous dTRPA1 channels in human cells. Our findings demonstrate that flies detect bacterial endotoxins via a gustatory pathway through TRPA1 activation as conserved molecular mechanism.sponsorship: Vlaams Instituut voor Biotechnologie Alessia Soldano Luis Franco Guangda Liu Natalia Mora Emre Yaksi Bassem A Hassanr Fonds Wetenschappelijk Onderzoek G.0702.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0077.15 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0680.10 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0681.10 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0503.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0654.15 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0761.10N Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0596.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0565.07 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar KU Leuven GOA/14/011 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar European Commission IUAP P7/13 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekensr KU Leuven OT/12/091 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar KU Leuven PF-TRPLe Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talavera (Vlaams Instituut voor Biotechnologie, Fonds Wetenschappelijk Onderzoek|G.0702.12, Fonds Wetenschappelijk Onderzoek|G.0077.15, Fonds Wetenschappelijk Onderzoek|G.0680.10, Fonds Wetenschappelijk Onderzoek|G.0681.10, Fonds Wetenschappelijk Onderzoek|G.0503.12, Fonds Wetenschappelijk Onderzoek|G.0654.15, Fonds Wetenschappelijk Onderzoek|G.0761.10N, Fonds Wetenschappelijk Onderzoek|G.0596.12, KU Leuven|GOA/14/011, KU Leuven|OT/12/091, European Commission|IUAP P7/13, KU Leuven PF-TRPLe)status: Publishe

    ASN892713 Supplemental Material - Supplemental material for Chemotherapeutic Effect of SR9009, a REV-ERB Agonist, on the Human Glioblastoma T98G Cells

    No full text
    Supplemental material, ASN892713 Supplemental Material for Chemotherapeutic Effect of SR9009, a REV-ERB Agonist, on the Human Glioblastoma T98G Cells by Paula M. Wagner, Natalia M. Monjes and Mario E. Guido in ASN Neuro</p

    A metabolic oscillator controls temporal changes in lipid metabolism and redox Istatus in tumor cells : implications in chemotherapy suceptibility

    Get PDF
    Biological clocks even present in immortalized cell lines, regulate physiological processes in a time-dependent manner, driving transcriptional and metabolic rhythms. The disruption of circadian rhythmicity in modern life (shiftwork, jetlag, etc.) may promote higher cancer risk and metabolic disorders.Fil: Wagner, Paula M.. Consejo Nacional de Investigaciones Científicas y Técnicas.Fil: Monjes, Natalia M.. Consejo Nacional de Investigaciones Científicas y Técnicas.Fil: Guido, Mario E.. Consejo Nacional de Investigaciones Científicas y Técnicas

    Рукописные тексты Н. Д. Пыдера на нижнелужском диалекте ижорского языка (р. Россонь) с комментариями

    No full text
    These are the texts written by a prominent activist and a speaker of the Vanakülä variety of the Lower Luga Ingrian dialect N. D. Põder (his memoirs were published in Russian as Põder 2019). He created an alphabet and was writing down texts, phrases and words in his native variety throughout years . These manuscripts with his original orthography, phonological transcription, morphological glossing, and Russian translation were prepared for publication and enriched with comments on particular aspects of phonetics and phonology, morphology, lexicon and syntax. The readings of the manuscripts by their author have been also recorded and used for this publication

    Large eddy simulations of side flow past a generic model of a high-speed train

    No full text
    Computational fluid dynamics (CFD) has been utilized to investigate straight and side flow over a simplified model of the concept high-speed Next Generation Train of the DLR. Large eddy simulation (LES) with a finite volume method for unstructured grids and a lattice Boltzmann method (LBM) were performed to compare the results. The Reynolds number of the flow was Re=2.1×10^5 and the investigated yaw angle was 30 degrees. The flow fields and the aerodynamic forces predicted with these two different methods are compared for the validation case of the flow past a sphere and the flow around the generic train model. Both approaches yield similar force predictions and exhibit different strengths and weaknesses throughout the computational process which are discussed

    Dynamics of non-pore-lining Orai1 transmembrane domains

    No full text
    Author Natalia Kriško, BScMasterarbeit Johannes Kepler Universität Linz 2025Arbeit gesperr

    Dynamics of non-pore-lining Orai1 transmembrane domains

    No full text
    Author Natalia Kriško, BScMasterarbeit Johannes Kepler Universität Linz 2025Arbeit gesperr

    Effects of extraction pH of chia protein isolates on functional properties

    Get PDF
    Fil: López, Débora Natalia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química Física. Área Fisicoquímica; Argentina.Fil: López, Débora Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Argentina.Fil: Ingrassia, Romina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química Física. Área Fisicoquímica; Argentina.Fil: Ingrassia, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Argentina.Fil: Ingrassia, Romina. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; Argentina.Fil: Busti, Pablo Andrés. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Tecnología. Área Tecnología de los Alimentos; Argentina.Fil: Wagner, Jorge Ricardo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina.Fil: Wagner, Jorge Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Argentina.Fil: Boeris, Valeria. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química Física. Área Fisicoquímica; Argentina.Fil: Boeris, Valeria. Pontificia Universidad Católica Argentina. Facultad de Química e Ingeniería del Rosario; Argentina.Fil: Boeris, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Argentina.Fil: Spelzini, Darío. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química Física. Área Fisicoquímica; Argentina.Fil: Spelzini, Darío. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Argentina.Fil: Spelzini, Darío. Pontificia Universidad Católica Argentina. Facultad de Química e Ingeniería del Rosario; Argentina

    Strategische Analyse in einem globalen, dynamischen Umfeld

    No full text
    Author: Natalia BaczykAbweichender Titel laut Übersetzung der Verfasserin/des VerfassersMasterarbeit Universität Linz 201
    corecore