29 research outputs found

    Live, virtual, and constructive-training environment: a vision and strategy for the Marine Corps

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    TheMarine Corps is developing the Live, Virtual, and Constructive–Training Environment (LVC-TE) program without a full vision and strategy. Without a properly developed vision and strategy, theMarine Corps will likely identify the wrong requirements and implement the program in a detrimentally inefficient manner. Through researchingMarine Corps policies and educating numerous Marines and civilians throughout HeadquartersMarine Corps and the operating forces, the author was able to determine that few personnel are aware of LVC-TE and there is no process in place to ensure appropriate representatives are educated on LVC-TE or are provided the opportunity to offer inputs to the requirements process. With root problems identified and by gathering information on potential technological improvements and training applications for LVC-TE, the author was able to devise numerous recommendations that provide a comprehensive vision and strategy for LVC-TE. Recommendations are made for a comprehensiveMarine Corps vision and strategy with a focus on assigning a capabilities integration officer to LVC-TE and adherence to an integrated process in order to ensure the correct requirements are identified, prioritized, and implemented in an efficient manner.Approved for public release; distribution is unlimited.Major, United States Marine Corpshttp://archive.org/details/livevirtualndcon109454395

    Protocolos de tratamento de leishmaniose visceral canina(LVC): Uma revisão de literatura

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    A geographically distributed disease, visceral leishmaniasis or kala-azar presents anthroponotic and/or zoonosis characteristics. The protozoan that causes leishmaniasis is sarcomastigóphore, genus Leishmania, having sandflies belonging to the Psychodidae family as vectors. CVL is considered a Public Health situation due to its rapid spread and high lethality. Dogs with CVL are considered one of the main reservoirs of the disease, some may be asymptomatic (they represent risks as sources of infection for sandflies). Clinical signs vary according to the species of parasite and the immune response of the host, and may affect the skin, mucous membranes and viscera. The treatment seeks to improve the therapeutic approach, clinical signs and reduction of the parasitic load. The present work aims to compile CVL treatment protocols reported in the literature, verifying their effectiveness. This research has a descriptive character, whose methodology was chosen qualitative and quantitative the research sought general characteristics about Leishmaniasis and CVL; subsequently there was delimitation for diagnosis, protocols/treatments, in order to answer the main objective of this research. The researched scientific articles were selected from a time frame of 2000-2012 and 2012-2022, the result may contain gaps regarding the mention of all articles, the number of articles listed possibly does not fully meet the reality of all research carried out, published, however, for the purpose proposed in the present work, the author considers the quantity relevant. At the end of the research, the results presented indicated protocols that are oriented according to the stage of the disease, immunomodulatory agents, leishmanicides, leishmaniatics. As for the established treatment protocols, there are: allopurinol with domperidone and miltefosine; LaSap with Allopurinol; amphotericin B + allopurinol + prednisone; meglumine antimoniate + allopurinol; liposomal meglumine antimoniate and monoclonal antibodies to canine IL-10 receptor alpha and beta subunits; Aminosidine; n methyl glucamine (Glucantime) and sodium stibogluconate (Pentostam); and Marbofloxacin. We glimpse, from the research, some treatment possibilities for CVL, with protocols that may be more viable, with encouraging results that correspond to the desires of researchers and veterinarians, the staging of the disease and the remission of clinical signs. more research is needed to delve deeper into these protocols, in order to ratify them and disseminate them to the various responsible bodies (WHO, CRMV, MS), thus providing a range of possibilities for tackling this disease that affects so many animals.Doença de distribuição geográfica, a leishmaniose visceral ou calazar apresenta características antroponótica e/ou zoonose. O protozoário causador da leishmaniose é sarcomastigófora, gênero Leishmania, tendo como vetores os flebotomíneos pertencentes à família Psychodidae. A LVC é considerada situação de Saúde Pública devido à disseminação rápida e alta letalidade. Os cães com LVC são considerados como um dos principais reservatórios urbanos da enfermidade, alguns podem ser assintomáticos (representam riscos como fontes de infecção para o flebotomíneo). Os sinais clínicos variam conforme a espécie do parasito e da resposta imune do hospedeiro, podendo comprometer pele, mucosas e vísceras. O tratamento busca melhorar conduta terapêutica, os sinais clínicos e redução da carga parasitária. O presente trabalho tem por objetivo compilar os protocolos de tratamento da LVC relatados na literatura, verificando sua eficácia. A presente pesquisa possui caráter descritivo, cuja metodologia escolhida foi a qualiquantitativa - as pesquisas buscaram características gerais sobre Leishmanioses e LVC; posteriormente houve delimitação para diagnóstico, protocolos/tratamentos, de maneira a responder o objetivo principal da presente pesquisa. Os artigos científicos pesquisados foram selecionados a partir de recorte temporal de 2000-2012 e 2012-2022, o resultado pode conter lacunas quanto a menção de todos os artigos, o quantitativo de artigos elencados possivelmente não atenda completamente a realidade de todos as pesquisas realizadas, publicadas, todavia, para o objetivo proposto no presente trabalho, o autor considera relevante o quantitativo. Ao término das pesquisas, o resultado apresentado indicou protocolos que se orientam segundo estadiamento da doença, agentes imunomoduladores, leishmanicidas, leishmanistáticos. Quanto aos protocolos de tratamento instituídas têm-se: alopurinol com domperidona e miltefosina; LaSap com Alopurinol; anfotericina B + alopurinol + prednisona; antimoniato de meglumina + alopurinol; antimoniato de meglumina lipossomal e anticorpos monoclonais anti subunidades alfa e beta do receptor de IL-10 canino; Aminosidina; n-metil glucamina (Glucantime) e estibogluconato de sódio (Pentostam); e Marbofloxacina. vislumbramos, a partir da pesquisa, algumas possibilidades de tratamento para LVC, com protocolos que podem ser mais viáveis, com resultados animadores ao que corresponde aos anseios dos pesquisadores e médicos veterinários, o estadiamento da doença e a remissão dos sinais clínicos.Naturalmente, ainda faz-se necessário mais pesquisas que se aprofundem acerca destes protocolos, a fim de ratificá-los e divulgá-los aos variados órgãos responsáveis (OMS, CRMV, MS), desta forma, proporcionar uma gama de possibilidades para o enfrentamento dessa doença que acomete tantos animais

    Purification and characterization of a novel incomplete-type vitellogenin protein (VgC) in Sakhalin taimen (Hucho perryi)

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    A novel, incomplete-type vitellogenin (VgC) and its derived yolk lipovitellin (LvC) were immunologically detected in female serum and egg extracts, respectively, of Sakhalin taimen (Hucho perryi) using a subtype-specific antiserum against LvC of grey mullet (Mugil cephalus). The taimen VgC was purified from the sera of vitellogenic females by a combination of gel filtration, anion exchange, and immunoadsorbent column chromatography. Gel filtration of the purified VgC revealed that it had an apparent native mass of ∼380 kDa, while the mass of the VgC polypeptide that appeared following SDS-PAGE was estimated to be ∼140 kDa. An antiserum was raised against the purified VgC and utilized for the development of a subtype-specific immunoassay for VgC. Levels of VgC in the serum of female taimen increased from 25 μg/mL to ∼1 mg/mL, with an increase of GSI. Levels of complete-type Vg and estradiol-17β (E2) in the serum of E2-administered juvenile taimen increased and reached peak levels similar to those found in vitellogenic females. Although VgC could be induced in the serum of E2-administered taimen, it stayed at levels (35.5-73 μg/mL) lower than those obtained in females. This is the first report on the presence of serum VgC and yolk LvC in a salmonid species; these findings indicate that for Sakhalin taimen, like other highly-evolved teleost species, this minor subtype of Vg is significant in the formation of egg yolk

    Optical Follow-up of Gravitational-wave Events during the Second Advanced LIGO/VIRGO Observing Run with the DLT40 Survey

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    We describe the gravitational-wave (GW) follow-up strategy and subsequent results of the Distance Less Than 40 Mpc survey (DLT40) during the second science run (O2) of the Laser Interferometer Gravitational-wave Observatory and Virgo collaboration (LVC). Depending on the information provided in the GW alert together with the localization map sent by the LVC, DLT40 would respond promptly to image the corresponding galaxies selected by our ranking algorithm in order to search for possible electromagnetic (EM) counterparts in real time. During the LVC O2 run, DLT40 followed 10 GW triggers, observing between similar to 20 and 100 galaxies within the GW localization area of each event. From this campaign, we identified two real transient sources within the GW localizations with an appropriate on-source time-one was an unrelated SN Ia (SN 2017cbv), and the other was the optical kilonova, AT 2017fgo/SSS17a/DLT17ck, associated with the binary neutron star (BNS) coalescence GW170817 (a.k.a gamma-ray burst GRB 170817A). We conclude with a discussion of the DLT40 survey's plans for the upcoming LVC O3 run, which include expanding our galaxy search fields out to D approximate to 65 Mpc to match the LVC's planned three-detector sensitivity for BNS mergers.</p

    A Lagrangian vertical coordinate version of the ENDGame dynamical core. Part I: Formulation, remapping strategies, and robustness

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    This is the author accepted manuscript. The final version is available from Wiley via the DOI in this record.Previous work provides evidence that Lagrangian conservation and related properties of a numerical model dynamical core can be improved by the use of a Lagrangian or quasi-Lagrangian vertical coordinate (LVC). Most previous model developments based on this idea have made the hydrostatic approximation. Here the LVC is implemented in a nonhydrostatic compressible Euler equation dynamical core using almost identical numerical methods to ENDGame, the operational dynamical core of the Met Office atmospheric Unified Model. This enables a clean comparison of LVCand height-coordinate versions of the dynamical core using numerical methods that are as similar as possible. Since Lagrangian surfaces distort over time, model level heights are continually reset to certain ‘target levels’ and the values of model fields are remapped onto their new locations. Different choices for these target levels are discussed, along with remapping strategies that focus on different conservation or balance properties. Sample results from a baroclinic instability test case are presented. The LVC formulation is found to be rather less robust than the height-coordinate version; some reasons for this are discussed.We are grateful to Nigel Wood for pointing out the computational mode of the LVC vertical discretization. We also thank two anonymous reviewers for their constructive comments on an earlier version of this paper. This work was funded by the Natural Environment Research Council under grant NE/H006834/1

    Sintagme s funkcionalnim glagolima u njemačkom korporativnom jeziku

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    Light Verb Constructions in Corporate German Language The thesis deals with Light Verb Constructions (LVC) in corporate German. The research includes analysis of structure and frequency of LVC in the above mentioned field of business German. Syntactical, morphological and semantic characteristics of LVC were analysed as well as their function in corporate German. The annual reports from 2011 of ten German corporations from German blue chip stock market index DAX served as a material for the research. The planned corpus volume is approximately 8000 LVC. The thesis gives more complete insight into the tendencies of this poorly researched field of German language which is elaborated and presented with empirical instruments and analytic-descriptive means of contemporary linguistics. The thesis consists of four larger parts: 1. Introduction, which includes topic description, motivation and previous researches on the given topic. 2. Part two, in which the theoretical basis of LVC is given. 3. Part three, which elaborates syntactical, morphological and semantic characteristics of LVC as well as their effects. 4. Part four, which represents the results of corpus analysis. Demonstrating the gained results in conclusion, the author of the thesis suggests possible further researches of LVC in the field of business German, possibilities of contrastive analysis of the gained results with those in other languages and possibility of using the gained cognitions in teaching business German at the non-philological colleges.Sintagme s funkcionalnim glagolima u njemačkom korporativnom jeziku Rad se bavi sintagmama s funkcionalnim glagolima (SFG) u njemačkome korporativnom jeziku. Istraživanje uključuje analizu strukture i frekventnosti SFG u gore navedenom dijelu njemačkoga poslovnog jezika. Analizirane su sintaktičke, morfološke i semantičke značajke SFG kao i njihova funkcija u njemačkome korporativnom jeziku. Kao građa za istraživanje poslužila su godišnja poslovna izvješća deset njemačkih korporacija iz njemačkoga dioničkog indeksa DAX iz 2011. Planirani opseg korpusa iznosio je ca. 8000 SFG. Radom je izvršen cjelovitiji uvid u tendencije ovoga slabo istraženog područja njemačkoga jezika, koje je obrađen i prezentiran empirijskim instrumentarijem i analitičko-deskriptivnim sredstvima suvremene lingvistike. Rad se sastoji od četiri veće cjeline: 1. Uvodnoga dijela, koji uključuje opis teme i motivacije te dosadašnja istraživanja na zadanu temu. 2. Drugoga dijela, u kojemu je dana teorijska podloga SFG. 3. Trećega dijela, koji obrađuje sintaktičke, morfološke i semantičke značajke SFG kao i njihove učinke. 4. Četvrtoga dijela, koji predstavlja rezultate korpusne analize. Predstavljajući dobivene rezultate u zaključku, autor rada predlaže moguća daljnja istraživanja sintagmi s funkcionalnim glagolima na području njemačkoga poslovnoga jezika, mogućnosti kontrastivne analize dobivenih rezultata s onima u drugim jezicima i mogućnost uporabe dobivenih spoznaja u nastavi poslovnoga njemačkog jezika na nefilološkim fakultetima

    RabbitStamp Test Sequence

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    # RabbitStamp sequence by LISA ULB The test sequence "RabbitStamp" is provided by Sarah Fachada, Yupeng Xie, Daniele Bonatto, Gauthier Lafruit, Mehrdad Teratani, members of the LISA department, EPB (Ecole Polytechnique de Bruxelles), ULB (Universite Libre de Bruxelles), Belgium. # License: CC BY-NC-SA ONLY Available for Academic Usage # Terms of Use: Anykind of publication or report using this sequence should refer to the following references. [1] Sarah Fachada, Yupeng Xie, Daniele Bonatto, Gauthier Lafruit, Mehrdad Teratani, "RabbitStamp Test Sequence", 2021. @misc{fachada_RabbitStamp_2021, title = {{RabbitStamp} {Test} {Sequence}}, author = {Fachada, Sarah and Xie; Yupeng and Bonatto, Daniele and Lafruit, Gauthier and Teratani, Mehrdad }, month = jul, year = {2021}, doi = {10.5281/zenodo.5053771} } [2] Sarah Fachada, Yupeng Xie, Daniele Bonatto, Gauthier Lafruit, Mehrdad Teratani, "[DLF] Plenoptic 2.0 Multiview Lenslet Dataset and Preliminary Experiments [m56429]", 2021. @article{fachada_RabbitStamp_2021, title = {[DLF] {Plenoptic} 2.0 {Multiview} {Lenslet} {Dataset} and {Preliminary} {Experiments} [m56429]}, author = {Fachada, Sarah and Xie; Yupeng and Bonatto, Daniele and Lafruit, Gauthier and Teratani, Mehrdad }, journal = {ISO/IEC JTC1/SC29/WG11}, month = apr, year = {2021} } [3] Sarah Fachada, Yupeng Xie, Daniele Bonatto, Gauthier Lafruit, Mehrdad Teratani, "[LVC] Update for RabbitStamp: Plenoptic 2.0 Multiview Lenslet Dataset [m57100]", 2021. @article{fachada_RabbitStamp_2021, title = {[LVC] {Update} for {RabbitStamp}: {Plenoptic} 2.0 {Multiview} {Dataset} [m56429]}, author = {Fachada, Sarah and Xie; Yupeng and Bonatto, Daniele and Lafruit, Gauthier and Teratani, Mehrdad }, journal = {ISO/IEC JTC1/SC29/WG11}, month = jul, year = {2021} } [4] Sarah Fachada, Yupeng Xie, Daniele Bonatto, Gauthier Lafruit, Mehrdad Teratani, "[LVC] Exploration Experiments using RabbitStamp Multiview Lenslet Images [m57101]", 2021. @article{fachada_RabbitStamp_2021, title = {[LVC] {Exploration} {Experiments} {Using} {RabbitStamp} {Multiview} {Lenslet} {Images} [m56429]}, author = {Fachada, Sarah and Xie; Yupeng and Bonatto, Daniele and Lafruit, Gauthier and Teratani, Mehrdad}, journal = {ISO/IEC JTC1/SC29/WG11}, month = jul, year = {2021} } # Production: Laboratory of Image Synthesis and Analysis, LISA department, Ecole Polytechnique de Bruxelles, Universite Libre de Bruxelles, Belgium. # Content: This dataset contains a test scene acquired with a raytrix camera [1] array of 7x3 views. For details of the dataset, please refer to the references mentioned above. The dataset contains: - a `depth_7x3_center` depth maps computed with DERS reference software [2] in yuv40016ble format and json configuration files to do so, - a `multiview_7x3_5x5_images` Calibrated subimages computed with RLC [3] in yuv42010ble format, the cameras.json with the camera parameters and view_synthesis.json with the view synthesis experiment. - a `multiview_7x3_lenslets` folder containing the lenslet views in yuv42010ble format, the Raytrix xml calibration file and RLC cfg file for conversion to multiview. # References and links: [1] Raytrix, https://raytrix.de/ [2] S. Rogge and D. Bonatto and J. Sancho and R. Salvador and E. Juarez and A. Munteanu and G. Lafruit, "MPEG-I Depth Estimation Reference Software", in 2019 International Conference on 3D Immersion (IC3D), 2019. [3] M. Teratani and T. Fujii, "[MPEG-I Visual] Conversion of Lenslet Data Capture by Single Focussed Plenoptic Camera to Multiview Video using RLC0.3 [N18567]", ISO/IEC JTC1/SC29/WG11, 201

    SOAR/Goodman Spectroscopic Assessment of Candidate Counterparts of the LIGO/Virgo Event GW190814*

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    On 2019 August 14 at 21:10:39 UTC, the LIGO/Virgo Collaboration (LVC) detected a possible neutron star-black hole merger (NSBH), the first ever identified. An extensive search for an optical counterpart of this event, designated GW190814, was undertaken using the Dark Energy Camera on the 4 m Victor M. Blanco Telescope at the Cerro Tololo Inter-American Observatory. Target of Opportunity interrupts were issued on eight separate nights to observe 11 candidates using the 4.1 m Southern Astrophysical Research (SOAR) telescope's Goodman High Throughput Spectrograph in order to assess whether any of these transients was likely to be an optical counterpart of the possible NSBH merger. Here, we describe the process of observing with SOAR, the analysis of our spectra, our spectroscopic typing methodology, and our resultant conclusion that none of the candidates corresponded to the gravitational wave merger event but were all instead other transients. Finally, we describe the lessons learned from this effort. Application of these lessons will be critical for a successful community spectroscopic follow-up program for LVC observing run 4 (O4) and beyond. © 2022. The Author(s). Published by the American Astronomical Society

    Optimization of CO2 Capture using Chemical Solvents from Steel Mill’s Works Arising Gases

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    Based on the Paris Accord, various governments have agreed to a long- term goal of keeping the increase in global average temperature to well below 2°C above pre-industrial levels; The Netherlands has committed to reduce its CO2 emissions with 80% by 2050; in this plan, the Dutch government has set an ambitious target for the industry to reduce their emissions by 70 million tonnes of CO2 annually. In The Netherlands, the steel industry contributes to nearly 7% of the total greenhouse gas emissions inventory. To meet the Dutch Government target, Tata Steel IJmuiden is exploring various options to reduce its CO2 emissions. One of the options being considered is CO2 Capture, whereby the CO2 could be captured from the Works Arising Gases (WAGs). Currently, the use of chemical absorption is the most mature technology to capture CO2 from any gas. This study has evaluated the performance, equipment sizing and cost of capturing CO2 using MEA or MDEA/Pz solvents. The performance of the chemical absorption process capturing 90% of the CO2 from a mixture of Blast Furnace Gas and Basic Oxygen Furnace Gas has been evaluated. The process was modeled in ASPEN Plus® . For cases using MEA as solvent, the conventional configuration were evaluated. It could be concluded that the optimal lean loading is around 0.19 mol/mol resulting to a specific reboiler duty of around 3.95 MJ/kg CO2 captured. Different advanced process flow configurations were also assessed. The results showed that the use of intercoolers in combination with a flash split-flow or LVC could result in a reduction of the specific reboiler duty. For cases using of MDEA and Pz as solvent, the conventional configuration operating with 1 and 10 bara absorber pressure were modeled. Resulting to a specific reboiler duty of 3.56 and 2.70 MJ/kg CO2 for 1 and 10 bara operating pressure, respectively. Furthermore, different advanced configurations were also assessed. This consisted of the incorporation of intercoolers and 1-stage or 2-stage configurations. With intercooling, the specific reboiler duty could be lowered down to 2.85 and 2.43 MJ/kg CO2 for operating pressure at 1 bara and 10 bara, On the other hand, based on the UCARSOL 1-stage configurations operating at 10 bara, the specific reboiler duty could be reduced down to 2.34 MJ/kg CO2. A reduction in specific reboiler duty for the 2-stage configuration could be significantly lowered. Preliminary economic evaluations were undertaken in this study to obtain the specific CO2 capture cost – based on CAPEX and OPEX estimates using 8% discount rate and an economic lifetime of 25 years. For the MEA cases evaluated, the costs of CO2 captured are in the range of 52.7 to 65.8 €/tonne CO2; the lowest cost is achieved with the LVC configuration in combination with intercooling. On the other hand, the results for the MDEA/Pz cases indicated that the costs of CO2 captured are in the range of 54.1 to 67.3 €/tonne CO2; the lowest cost is given in the configuration with intercooling operating at 1 bara
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