46,789 research outputs found

    Quantifying the Effect of Water Temperature, Soap Volume, Lather Time, and Antimicrobial Soap as a Factor in the Removal of Escherichia coli ATCC 11229 from Hands

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    The handwashing literature, while extensive, often contains conflicting data and key variables are understudied or not studied at all. Some handwashing recommendations are made without scientific support, and there is limited agreement between recommendations. The influence of key variables including soap volume, lather time, water temperature, and product formulation on hand wash efficacy was investigated. Baseline conditions were 1 mL of a bland (nonantimicrobial) soap, a 5 s lather time, and 38 °C (100 °F) water temperature. A nonpathogenic strain of Escherichia coli ATCC 11229 served as the challenge microorganism. Twenty volunteers (10 men, 10 women) participated in the study and each test condition had 20 replicates. An antimicrobial soap formulation (1% chloroxylenol, or PCMX) was not significantly different from the bland soap at removing E. coli under a variety of test conditions. Overall, the antimicrobial soap used in this study had a mean 1.94 log CFU reduction (range 1.83 to 2.10 mean log reduction), and bland soap had a mean 2.22 log CFU reduction (range 1.91 to 2.54 mean log CFU reduction). Overall, lather time did significantly influence efficacy in one scenario, in which a 0.5 greater log reduction was observed for a 20 s with bland soap compared to the baseline wash (P=0.020). Water temperature as high as 38°C (100°F) vs. a low of 15°C (60°F) did not have a significant effect on the reduction of bacteria during hand washing, however this resulted in an energy usage difference between the temperatures. No significant differences were observed between mean log reductions of men and women (men= 2.08 mean log reduction, women=2.08 mean log reduction, P=0.988). A large part of the variability in the data observed was between the volunteers. Understanding what behaviors and human factors influence hand washes the most may help future studies find which techniques can optimize the effectiveness of a hand wash.Peer reviewe

    Eccritotarsus curtipilis Carvalho & Schaffner 1986

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    Eccritotarsus curtipilis Carvalho & Schaffner, 1986 (Fig. 14) Eccritotarsus curtipilis Carvalho & Schaffner, 1986a: 310 (original description). Material examined. COLOMBIA. Risaralda: 1 ♂, SFF Otún Quimbaya, Urapanera, 1960 m, 4º44’N, 75º35’W, Malaise trap, 08–28.v.2003 (G. López) (IAVH-E-164652). Diagnosis. Body black and white. Head in dorsal view, antennal segments I (except base) and II, propleural areas anterior and posterior to the coxal cleft, xyphus and apex of cuneus black. Clavus dark brown to black; lateral margin with small median white spot. Corium with an irregular spot extending to the clavus or both clavus and embolium. Embolium with lateral margin predominantly black. Body length 3.48 mm. Associated/host plants. Unknown. Distribution. Colombia (Cundinamarca) (Carvalho & Schaffner 1986a); new department record: Risaralda. Comments. The median white spot on the lateral margin of clavus is important for this species identification and requires careful examination due to its small size.Published as part of Alvarez-Zapata, Alejandra, Ferreira, Paulo S. F. & Serna, Francisco, 2022, A taxonomic synopsis of the Eccritotarsini (Hemiptera: Heteroptera: Miridae Bryocorinae) of Colombia, pp. 101-151 in Zootaxa 5178 (2) on page 122, DOI: 10.11646/zootaxa.5178.2.1, http://zenodo.org/record/702216

    NTX: An Energy-efficient Streaming Accelerator for Floating-point Generalized Reduction Workloads in 22 nm FD-SOI

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    Specialized coprocessors for Multiply-Accumulate (MAC) intensive workloads such as Deep Learning are becoming widespread in SoC platforms, from GPUs to mobile SoCs. In this paper we revisit NTX (an efficient accelerator developed for training Deep Neural Networks at scale) as a generalized MAC and reduction streaming engine. The architecture consists of a set of 32 bit floating-point streaming co-processors that are loosely coupled to a RISC-V core in charge of orchestrating data movement and computation. Post-layout results of a recent silicon implementation in 22 nm FD-SOI technology show the accelerator’s capability to deliver up to 20 Gflop/s at 1.25 GHz and 168 mW. Based on these results we show that a version of NTX scaled down to 14 nm can achieve a 3× energy efficiency improvement over contemporary GPUs at 10.4× less silicon area, and a compute performance of 1.4 Tflop/s for training large state-of-the-art networks with full floating-point precision. An extended evaluation of MAC-intensive kernels shows that NTX can consistently achieve up to 87% of its peak performance across general reduction workloads beyond machine learning. Its modular architecture enables deployment at different scales ranging from high-performance GPU-class to low-power embedded scenario

    Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′

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    First evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)

    APC/C and SCFcyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry

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    SummaryThe anaphase promoting complex/cyclosome (APC/C) is an ubiquitin ligase and core component of the cell-cycle oscillator. During G1 phase, APC/C binds to its substrate receptor Cdh1 and APC/CCdh1 plays an important role in restricting S-phase entry and maintaining genome integrity. We describe a reciprocal feedback circuit between APC/C and a second ubiquitin ligase, the SCF (Skp1-Cul1-F box). We show that cyclin F, a cell-cycle-regulated substrate receptor (F-box protein) for the SCF, is targeted for degradation by APC/C. Furthermore, we establish that Cdh1 is itself a substrate of SCFcyclin F. Cyclin F loss impairs Cdh1 degradation and delays S-phase entry, and this delay is reversed by simultaneous removal of Cdh1. These data indicate that the coordinated, temporal ordering of cyclin F and Cdh1 degradation, organized in a double-negative feedback loop, represents a fundamental aspect of cell-cycle control. This mutual antagonism could be a feature of other oscillating systems

    Eccritotarsus tandapianus Carvalho & Schaffner 1986

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    * Eccritotarsus tandapianus Carvalho & Schaffner, 1986 (Figs. 21, 57–58) Eccritotarsus tandapianus Carvalho & Schaffner, 1986b: 477 (original description). Material examined. 1 ♂, no collection data (MEFLG 3691-1); COLOMBIA. Antioquia: 1 ♂, Caldas, weeds, 1.ix.1973 (A. Madrigal) (MEFLG 3691-2); 3 ♀, Concepción, rastrojo bajo, 1.ii.1997 (F.J. Serna & J.G. Hurtado) (MEFLG NC26635); 2 ♀, Jardín, 1.ii.1980 (A. Molina) (MEFLG NC26638); 1 ♀, Rionegro, 1.iv.1984 (R. Vélez) (ICN 092897); Boyacá: 1 ♂ 2 ♀, Duitama, El Carmen, 3450 m, 30.xi.1978 (I. de Arévalo) (ICN 092886); Caldas: 1 ♀, Manizales, Jardín Botánico, 2150 m, 5°06’15”N, 75°33’10”W, net sweeping, pasture, 29.iii.2010 (L. Lozano) (UNAB 619); Cauca: 1 ♀, PNN Munchique, Sector La Romelia, Zona abierta, 2640 m, 2º38’N, 76º54’W, Malaise trap, 10-26.vii.2004 (H. Pino) (IAVH-E-164687); 1 ♂, same but 24.v-09.vi.2004 (E. Fino) (IAVH-E-164591); Cundinamarca: 1 ♂, Anapoima, 679 m, 4°33’N, 74°32’W, 24.iii.2011 (A. Silva) (UNAB 618); 1 ♀, Anolaima, Vda. La María, 1596 m, 4°56’N, 74°28’W, 10.iv.2000 (A. Silva) (UNAB 616); 1 ♂, same but 1560 m, 4°56’N, 74°28’W, 3.iv.2011 (D. López) (UNAB 618); 1 ♂, Anolaima, Vda. Santo Domingo, 1605 m, 4°46’N, 74°28’W, 1.ix.2011 (J. Paredes) (UNAB 618); 1 ♂, Anolaima, 1616 m, 4°’59’N, 74°28’0.2”W, 1.ix.2011 (A. Perdomo) (UNAB 618); 1 ♂ 1 ♀, Arbeláez, 1417 m, 4°44’N, 74°32’W, 30.viii.1996 (A. Naranjo) (UNAB 616); 1 ♂, Cachipay, 1600 m, 4°35’N, 74°26’W, 27.i.1999 (D. Forero) (ICN 092896); 1 ♀, Cachipay, 1100 m, 4°43’N, 74°26’W, 8.ix.2001 (A. Camelo) (UNAB 619); 1 ♂, La Mesa, 1200 m, 4°37’N, 74°27’W, 11.ix.2003 (G. Guataquira) (UNAB 616); 1 ♂, La unión, Vda. Ucualoque, 2574 m, 4°60’N, 74°29’W, net sweeping, 22.iii.2012 (D. Villegas) (UNAB 617); 1 ♀, Mesitas del Colegio, 990 m, 4°34’N, 74°26’W, 5.iii.1994 (N. Pinzón) (UNAB 616); 1?, Quipile, Vda. Berlín, 1400 m, 4°44’N, 74°32’W, 1.xi.2000, Rubus sp. (Rosaceae)-“mora” (G. Manrique & M. Orozco) (UNAB 616); 1 ♂, San Antonio del Tequendama, Vda. San José, 1579 m, 4°37’37.14”N, 74°21’0.24”W, net sweeping, 18.iv.2015 (A. Cotrino) (UNAB 617); 1 ♀, Silvania, Vda. Yayala, 1470 m, 74°28’N, 74°25’W, net sweeping, 1.i.2012 (E. Díaz) (UNAB 617); 1 ♀, Silvania, 1470 m, 4°24’N, 74°23’W, 1.iv.2002 (A. Olaya & D. Villamil) (UNAB 616); 2 ♂ 4 ♀, Tena, around Laguna Pedro Palo, 4.iii.1999 (Curso entomología-ICN_UN) (ICN 092889); 1 ♂, Tena, Laguna Pedro Palo, 1384 m, 4°39’N, 74°23’W, 28.vi.1997 (F. Villamil) (UNAB 617); 1 ♂, Tibacuy, Vda. La Vuelta, Fca. La Esperanza, 1600 m, 4°20’N, 74°27’W, net sweeping, pasture, 1.v.2010 (O. Rodríguez) (UNAB 619); 1 ♀, Viotá, 567 m, 4°26’N, 74°31’W, 11.ii.1997 (W. Rabon) (UNAB 616); Huila: 2 ♂ 1 ♀, PNN Cueva de Los Guácharos, Cabaña Cedros, 2100 m, 1º37’N, 76º6’W, Malaise trap, 06-27.iv.2002 (J. Fonseca) (IAVH-E-164585); Quindío: 5 ♂, Armenia, manual collecting, 19.i.2000, Eucalyptus sp. (Myrtaceae) (A. Madrigal) (MEFLG 7463-1); 1 ♂, Montenegro, Fca. La Estancia, 1294 m, 4°34’N, 75°45’W, 20.v.2000 (P. Alvarado) (UNAB 616); 1 ♂, Salento, Valle del Cocora, 23.vii.1977 (R. Restrepo) (ICN 092895); Risaralda: 1 ♂, SFF Otún Quimbaya, Urapanera, 1960 m, 4º44’N, 75º35’W, Malaise trap, 04-19.iv.2003 (G. López) (IAVH-E-164741); 1 ♂, same but 08-23.vii.2003 (G. López) (IAVH-E-164707); Santander: 1 ♀, Cañaverales, 1780 m, 3.xi.1976 (I. de Arévalo) (ICN 092873); 2 ♂ 2 ♀, same but 3.xi.1978 (I. de Arévalo) (ICN 092876); 1 ♀, Cañaverales, Río Luisito, 1780 m, 1.xii.1980 (I. de Arévalo) (ICN 092875); 1 ♂ 6♀, Charalá, Virolin, Río Luisito, 1780 m, 1.xii.1978 (I. de Arévalo) (ICN 092879); Tolima: 2 ♀, Icononzo, Vda. El Palmar, 1710 m, 20.iii.1978 (R. Restrepo) (ICN 092898). Diagnosis. Body yellowish and black. Head in dorsal view, pronotum, propleural areas anterior and posterior to the coxal cleft and xyphus black. Corium whitish with transverse stripe, always extending to the clavus and generally to the embolium, sometimes narrowing towards the embolium. Silvery pruinosity absent. Body length 3.80–4.60 mm. Right paramere (Fig. 57) with basal process short and wide; body wide with a concavity close to the basal process; sensory lobe absent; apical process elongate, with lateral protuberance. Left paramere (Fig. 58) with basal process widened towards the body; body wide and convex with lateral protuberance; sensory lobe absent; apical process elongate, distally bent, with excavation before apex, apex truncate. Associated plants. Eucalyptus sp. (Myrtaceae) and Rubus sp. (Rosaceae). Distribution. Ecuador (Carvalho & Schaffner 1986b). Colombia (Antioquia, Boyacá, Caldas, Cauca, Cundinamarca, Huila, Quindío, Risaralda, Santander, Tolima). Comments. This is the first record of this species in Colombia.Published as part of Alvarez-Zapata, Alejandra, Ferreira, Paulo S. F. & Serna, Francisco, 2022, A taxonomic synopsis of the Eccritotarsini (Hemiptera: Heteroptera: Miridae Bryocorinae) of Colombia, pp. 101-151 in Zootaxa 5178 (2) on pages 125-126, DOI: 10.11646/zootaxa.5178.2.1, http://zenodo.org/record/702216

    A Scalable Near-Memory Architecture for Training Deep Neural Networks on Large In-Memory Datasets

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    Most investigations into near-memory hardware accelerators for deep neural networks have primarily focused on inference, while the potential of accelerating training has received relatively little attention so far. Based on an in-depth analysis of the key computational patterns in state-of-the-art gradient-based training methods, we propose an efficient near-memory acceleration engine called NTX that can be used to train state-of-the-art deep convolutional neural networks at scale. Our main contributions are: (i) a loose coupling of RISC-V cores and NTX co-processors reducing offloading overhead by 7 x over previously published results; (ii) an optimized IEEE 754 compliant data path for fast high-precision convolutions and gradient propagation; (iii) evaluation of near-memory computing with NTX embedded into residual area on the Logic Base die of a Hybrid Memory Cube; and (iv) a scaling analysis to meshes of HMCs in a data center scenario. We demonstrate a 2.7 x energy efficiency improvement of NTX over contemporary GPUs at 4.4 x less silicon area, and a compute performance of 1.2 Tflop/s for training large state-of-the-art networks with full floating-point precision. At the data center scale, a mesh of NTX achieves above 95 percent parallel and energy efficiency, while providing 2.1 x energy savings or 3.1 x performance improvement over a GPU-based system

    Corrigendum to “Presence and function of kisspeptin/KISS1R system in swine ovarian follicles” (Theriogenology (2018) 115 (1–8), (S0093691X1830147X), (10.1016/j.theriogenology.2018.04.006))

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    The authors regret the following changes to the author group G. Basinia, F. Grassellia, S. Bussolatia, R. Ciccimarraa, M. Maranesib, A. Bufalarib, C. Dall'Agliob, F. Parilloc,#, M. Zeranib,c,*. a Dipartimento di Scienze Mediche Veterinarie, Università di Parma, 43126 Parma, Italy. b Dipartimento di Medicina Veterinaria, Università di Perugia, 06126 Perugia Italy. c Scuola di Bioscienze e Medicina Veterinaria, Università di Camerino, 62024 Matelica Italy. # Deceased. * Corresponding author: tel.: +39 0755857642; fax +39 0755857654. E-mail address: [email protected] (M. Zerani). And to the acknowledgements and figures

    Measurement of the CP-violating phase \phi s in Bs->J/\psi\pi+\pi- decays

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    Measurement of the mixing-induced CP-violating phase phi_s in Bs decays is of prime importance in probing new physics. Here 7421 +/- 105 signal events from the dominantly CP-odd final state J/\psi pi+ pi- are selected in 1/fb of pp collision data collected at sqrt{s} = 7 TeV with the LHCb detector. A time-dependent fit to the data yields a value of phi_s=-0.019^{+0.173+0.004}_{-0.174-0.003} rad, consistent with the Standard Model expectation. No evidence of direct CP violation is found

    Lympha technique for primary and early secondary prevention of lymphedema following cancer treatment

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    LYMPHA proved to be an effective preventive procedure that contributes in giving our oncological patients a good quality of life. In this presentation, the author will report indications, technical aspects and benefits of LYMPHA technique
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