1,180 research outputs found

    Regulatory factors of basal F2-isoprostane formation: Population, age, gender and smoking habits in humans

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    Oxidative stress is assumed to be the key underlying factor in the pathogenesis of many common diseases. This study describes the basal levels of 8-iso-PGF(2alpha ), a major F(2)-isoprostane and an in vivo oxidative stress biomarker in healthy subjects from three countries, namely Italy, Poland and Sweden, in relation to their smoking habits, age and gender. It studied urinary 8-iso-PGF(2alpha ) in 588 subjects from Sweden (n=220), Italy (n=203) and Poland (n=165). Polish subjects had the highest levels of F(2)-isoprostanes followed by the Swedish and Italians when adjusted for smoking, age, sex and creatinine and the inter-country differences were statistically significant. Smokers had significantly higher levels of 8-iso-PGF(2alpha ) compared to non-smokers in all countries and there was a moderate decrease with age. Women had only slightly lower 8-iso-PGF(2alpha ) than men. There is a difference in F(2)-isoprostane levels in vivo between countries. Smoking, age and gender affect isoprostane formation and should be taken into consideration in clinical studies of oxidative stress.</p

    Bahumukhī mana, bahurupī prema

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    The document contains a novel written by the Bengali author Nirpendra Kumar Basu (1898-1979). The monograph is from the private collection of Sharmadip Basu

    Outer Length Scales in Nocturnal Stable Boundary Layers

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    Recently, Basu and Holstlag (2021) proposed a unified framework for describing outer length scales (OLS). By utilizing this framework, we document various characteristics of OLS in nocturnal boundary layers over the US Great Plains.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Atmospheric Remote Sensin

    Exhaled breath condensate biomarkers of airway inflammation and oxidative stress in COPD

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    Exhaled breath condensate (EBC) is a noninvasive method for collecting airway secretions and for studying the composition of the airway lining fluid. Several biomolecules, including leukotrienes, prostaglandins, isoprostanes, hydrogen peroxide, nitric oxide-derived products, hydrogen ions, and adenosine triphosphate, have been measured in healthy subjects. Some of these inflammatory mediators are elevated in patients with chronic obstructive pulmonary disease (COPD). Analysis of biomolecules in EBC is potentially useful for monitoring of lung inflammation and oxidative stress, which is an important component of inflammation, in patients with COPD. As it is completely noninvasive, EBC might also be suitable for longitudinal studies, and for monitoring the effects of pharmacological therapy in patients with COPD. Different profiles of biomarkers in EBC might reflect different aspects of lung inflammation or oxidative stress. Identification of selective profiles of biomarkers in EBC in lung diseases might have a value for differential diagnosis in respiratory medicine. However, several methodological aspects have to be formally addressed and standardization of EBC methodology is required before this technique can be considered for application in the clinical setting

    Cupid Joins the War

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    The author explores the history of love and sex in war though the ages. This monograph is from the private collection of Sharmadip Basu, Kolkata, W.B., India

    Inflammatory F-2-isoprostane, prostaglandin F-2 alpha, pentraxin 3 levels and breast cancer risk: The Swedish Mammography Cohort

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    The authors greatfully acknowledge Prof. Karl Michaelsson for providing support in the organisation of SMC cohort and technical assistance of Ms. Lillemor Kallstrom and Ms. Carina Branstrom. The authors are indebted to the Conseil Regional d'Auvergne, Clermont-Ferrand, France and the Clermont Universite, University d'Auvergne, Clermont-Ferrand, France for a Chaire d'Excellence Professor to Samar Basu and a Research Grant to Prof. Samar Basu and Prof. Marie-Paule Vasson to support the workIntroduction:Breast cancer is a common cancer among women. Identifying cellular participation of F-2-isoprostane, prostaglandin F-2 alpha, (PGF(2 alpha)) and pentraxin 3 (PTX3) in cancer we evaluated whether their prediagnostic systemic levels that originate from different inflammatory pathways were associated with breast cancer risk.Methods: Seventy-eight breast cancer cases diagnosed after blood collection and 797 controls from the Swedish Mammography Cohort were analysed for urinary F-2-isoprostane, PGF(2 alpha) and plasma PTX3 levels.Results: None of the biomarkers investigated were significantly associated with breast cancer risk. However, there was the suggestion of an inverse association with PTX3 with multivariable adjusted ORs (95% CI) of 0.56 (95% CI=0.29-1.06) and 0.67 (95% CI=0.35-1.28) for the second and third tertiles, respectively (p(trend)=0.20). No associations were observed between F-2-isoprostane (OR=0.87; 95% Cl=048-1.57; p(trend)=0.67) and PGF(2 alpha) metabolite (OR=1.03; 95% CI=0.56-1.88; p(trend)=0.91) comparing the top to bottom tertiles.Conclusions: The systemic levels of F-2-isoprostane, PGF(2 alpha) and PTX3 witnessed in women who later developed breast cancer may not provide prognostic information regarding tumor development in spite of their known involvement in situ cellular context. These observations may indicate that other mechanisms exist in controlling cellular formation of F-2-isoprostane, PGF(2 alpha) and PTX3 and their systemic availability in breast cancer patient

    Magnanimous Kunti by Samaresh Basu/ সমরেশ বসুর কলমে মনস্বিনী কুন্তী

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    Samaresh Basu wrote a number of books based on Puran-Mahabharata under the pseudonym Bhramar and Kalkoot. Such as, ‘Shamba (1978)’, ‘Juddher Sesh Senapati (1984)’, ‘Prachetas (1984)’, \u27Pritha (1986)\u27, ‘Antim Pranay (1987)’ etc. ‘Pritha’ was published in the magazine \u27Prasad\u27 under the pseudonym \u27Bhramar\u27. In such books, the author analyzed the traditional story of the Puranas in a new perspective. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; One of the memorable Panchakanyas in Puranas, Empress Kunti has been recreated in the light of the author\u27s spirit in this book. In the present article we will discuss how the character of Kunti has been recreated by Samaresh Basu in \u27Pritha\u27. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; At the beginning of the story, before reaching the context of Kunti, the author undertakes a very realistic analysis of heaven-hell, Gods-demons, Samhita era-Puranic era, male-female relationship, marriage customs, child birth and the position of women in society. Then he explained the solitude, self-immolation and transition of Kunti from a feminist perspective. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The story of love-marriage-motherhood-heroism-restraint-pain-sacrifice of this remarkable female character of Mahabharata has been captured in a new way in the unique writing of Kalkoot. Inventing many thoughtful arguments the author tried to establish the father-son relationship between Yudhisthira-Vidura and Karna-Durbasha. How the author incarnated new contexts in the familiar story of Mahabharata and how he made it acceptable by arranging relevant arguments in favour of his new thoughts – this essay will try to elaborate these points

    Metrocoris dinendrai Basu, Polhemus and Subramanian, NEW SPECIES

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    Metrocoris dinendrai Basu, Polhemus and Subramanian, NEW SPECIES Figs. 33–44 Material examined. Holotype: Apterous male: INDIA, West Bengal, Darjeeling District, roadside cascades within Neora Valley National Park, 27.0828°N, 88.7437°E, 2006m. asl, 3.X.2012, coll. S. Basu, deposited at the Zoological Survey of India, H.Q., Kolkata (NZSI) Reg. No. 4774/H15. Paratypes: INDIA, West Bengal: 1 apterous male, 1 apterous female, 31 nymphs: same data as holotype Reg. No. 4775/H15; 2 apterous males, 1 apterous female, 1 macropterous female, 5 nymphs, Darjeeling District, stream on the way to Chengey Falls, near Lava, 27.0511°N, 88.6800°E, 1639 m. asl, 3.X. 2012, coll. S. Basu (NZSI) Reg. No. 4776/H15; 4 apterous males, 2 apterous females, 1 nymph, Darjeeling District, stream near Gorubathan, 26.96636°N, 88.7000°E, 370 m. asl., 1.X.2013, coll. S. Basu, (NZSI) Reg. No. 4777/H15. Description. Apterous male (Holotype): Fig.33 Size: Body length 5.42 mm, maximum width across mesoacetabula 2.53 mm. Colour: Dorsal body coloration yellowish to orange with dorsal black markings (Fig. 33). Interocular dark mark rectangular, bifid posteriorly, anterior margin not connected with dark mark of postclypeus, posterior portion in some individuals connected with dark inner margin of eye. Antennal segments black, with first segment yellow basally. Eyes black. Dark marks on pronotum broad T-shaped, connected to propleural margin (Fig.33). Meso- and metanota pale orange with dark markings as in Figs. 33, sublateral dark stripes broader than yellowish part on apical half, longitudinal dark stripe of mesopleuron extending nearly through its length. Abdominal terga black except segment VIII. Thoracic venter black, with a deep yellowish patch laterally (Fig. 36). Abdominal sterna II– VI black, sterna VII–VIII yellowish posteriorly. Fore femur black, basal one-fourth of ventral and dorsal surfaces yellowish, fore tibia and tarsus black. Rostrum black with pale yellowish lateral margins. Structural characteristics: Head width 1.36, length 0.73. Interocular region wider than eye, widths 0.61 and 0.25 respectively. Eye length 0.62, posterior half of eye covering anterior one fourth of propleuron. Length of antennal segments I–IV: 2.29, 0.97, 0.88, 0.65, first segment longer than combined lengths of remainder. Rostrum length 1.46, surpassing fore trochanter. Pronotum slightly bulbous in male, wider than long, width 1.61, length 0.57, slightly wider than head. Meso- and metanota 1.12 times wider than combined length, width 2.55, length 2.27. Fore femur (Fig. 39) slender and slightly curved at middle, ratio of length/width approximately 6.5, ventral surface with small constriction near middle, without indentation or tooth, with short dense hair fringe ventrally near apex, inner margin with rows of short hairs. Inner margin of fore tibia not modified, bearing rows of short hairs. Second tarsal segment long. Pretarsus with pair of sharp claws. Hind trochanter lacking modifications. Abdominal terga with prominent golden pubescence, combined length 1.83, maximum width 1.21. Abdominal sternum VIII bearing long dense hair fringe (Fig. 37). For measurements of leg segments see Table 1. Male genitalia: Male abdominal sternum VIII (Fig. 37) elongate, sub-oval, length 1.27, width 0.86, densely clothed with fringe of golden hairs. Posterior margin of abdominal tergum VIII straight. Pygophore (Fig. 42) elongate, heavily setiferous, apex truncate. Proctiger (Fig. 41) moderately elongate, lateral margins slightly convex, isolating angular basal lobes, apex broadly rounded, posterior margin with dense hair fringe. Parameres symmetrical (Fig.43) strongly curved near midpoint, apical section expanded to small head with outer margin concave, apex blunt, inner and outer margins with long distinct setae, several whitish dots distributed throughout. Endosomal sclerites as in Fig. 44. Apterous female: Fig. 34 Size: Body length 4.41–4.55, maximum width across mesoacetabula 2.29–2.31. Colour: Pattern of dark markings similar to that of male except much wider and more prominent; fore femur slender, lacking median invaginations; sterna VI–VII yellowish. Structural characteristics: Head length 0.74, width 1.21. Length of antennal segments 1–4: 1.87, 0.65, 0.60, 0.72. Eye length 0.61, width 0.24, interocular width 0.66. Length of rostrum 1.45. Pronotum wider than long, length 0.50, width 1.54. Combined lengths of meso- and metanota 2.12, width 2.21. Fore femur length/width ratio 6.3, lacking medial constriction; fore pretarsi bearing sharp, curved claws; hind trochanter lacking modifications. Abdominal sterna II–VI combined length 0.96, maximum width 1.57. For measurements of leg segments see Table 2. Female terminalia: Abdominal sternum VII semi-circular, length 0.30, width 1.07, slightly constricted laterally, clothed with short golden pubescence. Macropterous male: Unknown. Macropterous female: Fig. 35 Size: Body length 5.32, maximum width across mesoacetabula 2.67. Structural characteristics: Golden brown dorsally, marked with prominent black markings as shown in Fig.35. Median length of pronotum 2.41, humeral width 1.72, length of lateral margin from anterior angle to humerus 0.89, length of lateral margin from humerus to apex 1.76, apex of pronotum pointed, medially slightly bulged. Etymology. This name “dinendra” is a patronym dedicated to Professor Dinendra Roychoudhury of Department of Zoology of University of Calcutta, who had encouraged the first author to carry out entomological research. Habitat. This species was collected from high mountainous cascades within the Neora Valley National Park of the Darjeeling District in West Bengal. The insects were found in steep, rocky areas flooded with splashing water, and appear adapted to the cold waters. A preference for rushing, high gradient upland streams has also been observed by the second author (DP) for another currently undescribed species of the Metrocoris compar species group collected in northern Vietnam, suggesting this habitat association may be typical of the group as a whole. Comparative notes. Metrocoris dinendrai sp. nov. belongs to Metrocoris compar group based on the structure of male fore femur, which is slender and slightly curved; the strongly curved male parameres; the elongate male pygophore which bears dense dark pilosity; and the laterally constricted female terminal abdominal sterna. This new species can be recognized within this group by the distinctive shape of male paramere, which has a a slightly expanded apex that is somewhat concave on its outer margin (Fig. 43); the structure of male endosomal sclerites (Fig. 44); and the female trochanter clothed with thick black bristles. Within the Metrocoris compar group, M. dinendrai seems most similar to M. pardus from the Malay Peninsula (Zettel, 2011a), but has the distal arm of the male paramere more slender and elongate, and the outer margin of the paramere apex concave rather than convex (compare Fig. 43 to Fig. 8 in Zettel, 2011a). The basal lobes on the male proctiger also are more angular than in M. pardus, whereas the internal sclerotization of the male endosoma is similar in both species.Published as part of Basu, Srimoyee, Polhemus, D. A., Subramanian, K. A., Saha, G. K. & Venkatesan, T., 2016, Metrocoris Mayr (Insecta: Hemiptera: Gerridae) of India with descriptions of five new species, pp. 257-277 in Zootaxa 4178 (2) on pages 265-267, DOI: 10.11646/zootaxa.4178.2.5, http://zenodo.org/record/25873

    The regional comprehensive economic partnership : new paradigm or old wine in a new bottle?

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    For more about the East-West Center, see http://www.eastwestcenter.org/Sanchita Basu Das, ISEAS Fellow and Lead Researcher at the ASEAN Studies Centre, explains that, "Although RCEP could be an easier negotiating path for the ASEAN nations and others, there is a high chance that it may lose sight of its strategic goals, such as maintaining centrality, that make it an attractive proposition in the first place." The views expressed in this publication are those of the author and do not necessarily reflect the policy or position of the East-West Center or any organization with which the author is affiliated

    Book Reviews

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    BOOK REVIEWS Letter From An Author - ASOKE BASU The Limits of Reform: Women, Capital and Welfare by Jennifer G. Schirmer - Reviewed by KRISTINE NELSON 542 Marxism and Domination: A Neo-Hegelian. Feminist, Psychoanalytic Theory of Sexual, Political and Technological Liberation, by Isaac D, Balbus - Reviewed by DAN LA BOTZ 53
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