39 research outputs found
The indetermination of the criminal compliance and the principle of legality [La indeterminación del criminal compliance y el principio de legalidad]
No full textThis paper is a critical analysis of the statutory regulation of criminal compliance models in criminal law. In the following pages, the author maintains that the model imposed in Act No. 20.393 has serious determination problems, which affect the principle of legality in its attribute of lex certa. The creation of an enforced self-regulation model with unclear or incomplete obligations, cannot justify the imposition of criminal sanctions in the case of their infraction. An analysis of other criminal compliance models in Chile and in other jurisdictions shows, that there are alternative regulatory techniques that preserve the legality principle. The author proposes the specification of the criminal compliance mandates through infra-legal provisions dictated by sectorial regulators, while respecting the constitutional requisites for incomplete penal statutes. © 2018 Centro Estudios Derecho Penal. All rights reserved.Universidad Autónoma de Chil
Functional impact of cancer-associated mutations in the tumor suppressor protein ING4
No full textInhibitor of growth 4 (ING4) is a member of the ING family of tumor suppressor proteins. In this study, we have analyzed the impact of two mutations in ING4 associated with human tumors (Y121N and N214D), testing their behavior in a series of functional, biochemical and structural analyses. We report that the N214D mutation dramatically dampened the ability of ING4 to inhibit proliferation, anchorage-independent growth or cell migration or to sensitize to cell death. In turn, the Y121N mutant did not differ significantly from wild-type ING4 in our assays. Neither of the mutations altered the normal subcellular localization of ING4, showing predominantly nuclear accumulation. We investigated the molecular basis of the defect in the activity of the N214D mutant. The folding and ability to bind histone marks of ING4 was not significantly altered by this mutation. Instead, we found that the functional impairment of the N214D mutant correlates with reduced protein stability due to increased proteasome-mediated degradation. In summary, our data demonstrates that a point mutation of ING4 associated to human tumors leads to the loss of several essential functions of ING4 pertinent to tumor protection and highlight the importance of ING4 function to prevent tumorigenesis. © The Author 2010. Published by Oxford University Press. All rights reserved.Spanish Ministry of Science and Innovation (BFU2006-10882 and SAF2009-09031 to I.P., CTQ2008-03115/BQU to F.J.B. and SAF2007-62292 to B.J.).Peer Reviewe
Percepções de gestores sobre o comportamento dos funcionários em situações de mudanças tecnológicas
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-graduação em PsicologiaAs constantes inovações tecnológicas ocorridas em escala mundial têm levado os gestores a promoverem mudanças em suas organizações com o objetivo de mantê-las estáveis, eficientes e em desenvolvimento. Estas mudanças têm gerado impactos sociais, estruturais e culturais dentro das organizações e vem sendo transformado em um dos principais focos de preocupação dos dirigentes das organizações de trabalho para atingir seus objetivos. Em razão disto, esta pesquisa teve como objetivo geral pesquisar quais as percepções dos gestores sobre os comportamentos dos funcionários em situações de mudanças tecnológicas. A escolha de pesquisar sobre a percepção dos gestores sobre o comportamento dos funcionários em situações de mudança tecnológica tem como base a premissa de que os gestores são responsáveis pela condução das mudanças. A amostra foi formada por sete gestores com atuação em uma organização prestadora de serviços, situada na grande Florianópolis no estado de Santa Catarina. Os dados foram coletados por meio de entrevistas semi-estruturadas e análise de documentos. A análise dos dados possibilitou identificar as percepções dos gestores sobre os comportamentos dos funcionários em situações de mudanças tecnológicas, desde a cooperação com o processo, a indiferença, resistências passivas e ativas. Além disso, delineou a influência da disseminação das informações sobre a mudança como fator relevante para a mudança tecnológica. Os resultados obtidos por meio deste estudo confirmaram que as percepções dos gestores influenciam diretamente suas ações sobre o quadro funcional e demonstraram a necessidade de preparação dos quadros gerenciais para promover as mudanças tecnológicas. The constant technological innovations occurred in worldwide have led the managers to promote changes in their organizations in order to keep them stable, efficient and development. These changes have generated social impacts, within the structural and cultural organizations and has been transformed into one of the main focuses of concern for leaders of organizations working to achieve their goals. Because of this, this research aimed to find what general managers' perceptions about the behaviour of officials in situations of technological change. The choice of search on the perception of managers on the behavior of officials in situations of technological change is based on the premise that managers are responsible for driving the changes. The sample was made up seven managers with performance in an organization that provides services, located in the vast Florianopolis in the state of Santa Catarina. Data were collected through semi-structured interviews and examining documents. Data analysis also identified managers' perceptions about the behaviour of officials in situations of technological change, since cooperation with the process, indifference, active and passive resistance. Moreover, outlined the influence of the spread of information about the change as a factor relevant to technological change. The results obtained through this study confirmed that the perceptions of managers directly influence their actions on the operational framework and demonstrated the need for preparation of management frameworks to promote technological change
Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (Human Genetics, (2019), 138, 4, (307-326), 10.1007/s00439-019-01989-8)
No full textEvery author has erroneously been assigned to the affiliation “62”. The affiliation 62 belongs to the author Graham Casey. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature
Uso De Enxerto ósseo Autógeno Nas Reconstruções Da Cavidade Bucal. Análise Retrospectiva De 07 Anos
No full textCurrently, there is great demand for patients who requires treatment with bone integrable dental implants, however this situation is often hampered by the changes in the edentulous alveolar ridge, which may make the installation of the implant more complicated. The autogenous bone graft are current days the choice of treatments for patients with insufficient bone volume to receive implants and that to receive bone integrable implants. The purpose of this study was to evaluate retrospectively the use of autogenous bone graft in patients treated in the Surgery Area of Oral and Maxillofacial from the College of Dentistry of Piracicaba, by de State University of Campinas in the period July 2001 to July 2008. The results show that the intraoral donors areas were used in 95,1% of the cases, and that the maxillary tuberosity was used in 39.8% of the cases, the ascending branch in 31,4% and the mandibular symphysis in 28,8% of the cases. The "onlay" block graft was the most commonly technique employed (53,7%), followed by the particulate bone graft (36,6%) and by sinus lifting of the maxillary (9,7%). In conclusion, whenever possible we should choose intraoral donors areas, and in this work, these donors areas were the most commonly employed, and the maxillary tuberosity the most used.504221225Atwood, D.A., Reduction of residual ridges: a major oral disease entity (1971) J Prosthet Dent, 26, pp. 266-279Tallgren, A., The continuing reduction of the residual alveolar ridges in complete denture wearers: a mixed-longitudinal study covering 25 years (1972) J Prosthet Dent, 27, pp. 120-132Ashman, A., Bruins, P., Prevention of alveolar bone loss postextraction with HTR grafting material (1985) Oral Surg Oral Med Oral Pathol, 60, pp. 146-153Hjorting-hansen, E., Adawy, A.M., Hillerup, S., The pattern of postoperative bone resorption following mandibular vestibulolingual sulcoplasty with free skin graft (1983) J Oral Maxillofac Surg, 41, pp. 358-364Piecuch, J.F., Segal, D., Grasso, J.E., Augmentation of the atrophic maxilla with interpositional autogenous bone grafts (1984) Maxillofac Surg, 12, pp. 133-138Misch, C.M., Comparison of intraoral donor sites for onlay grafting prior to implant placement (1997) Int J Oral Maxillofac Implants, 12, pp. 767-776Garg, A.K., Morales, M.J., Navarro, I., Duarte, F., Autogenous mandibular bone grafts in the treatment of the resorbed maxillary anterior alveolar ridge: rationale and approach (1998) Implant Dent, 7, pp. 169-176Lekholm, U., Gunne, J., Henry, P., Higuchi, K., Linden, U., Bergstrom, C., Steenberghe, D.V., Survival the Branemark Implant in partially. edentolous jaws: a 10-year prospective multicenter study (1999) Int J Oral and Maxillofac Implants, 14, pp. 639-645Keller, E.E., Eckert, S.E., Tolman, D.E., Maxillary antral and nasal one-stage inlay composite bone graft: preliminary report on 30 recipient sites (1994) J Oral Maxillofac Surg, 52, pp. 438-447Branemark, P.I., Lindstrom, J., Hallén, O., Breine, U., Jeppson, P.-h., Ohman, A., Reconstruction of the defective mandible (1975) Scand J Plast Reconstr Surg, 9, pp. 116-128Triplett, R.G., Schow, S.R., Autologous bone grafts and endosseous implants: complementary techniques (1996) J Oral Maxillofac Surg, 54, pp. 486-494Montazem, A., Valauri, D.V., St-Hilaire, H., Buchbinder, D., The mandibular symphysis as a donor site in maxillofacial bone grafting: a quantitative anatomic study (2000) J Oral Maxillofac Surg, 58, pp. 1368-1371Raghoebar, G.M., Batenburg, R.H.K., Vissink, A., Reintsema, H., Augmentation of localized defects of the anterior maxillary ridge with autogenous bone before insertion of implants (1996) J Oral Maxillofac Surg, 54, pp. 1180-1185Raghoebar, G.M., Meijndert, L., Kalk, W.W.I., Vissink, A., Morbidity of mandibular bone harvesting: a comparative study (2007) Int J Oral Maxillofac Implants, 22, pp. 359-365Serra E Silva, F.M., Cortez, A.L.V., Moreira, R.W.F., Mazzonetto, R., Complications of intraoral donor site for bone grafting prior to implant placement (2006) Implant Dent, 15, pp. 420-426Misch, C.E., (2000) Implantes dentários contemporãneos, , 2 ed. São Paulo: SantosBezerra, F.J.B., Lenharo, A., (2000) Técnica clínica avançada em implantodontia, , São Paulo: Artes MédicasClavero, J., Lundgren, S., Ramus or chin grafts for maxillary sinus inlay and local onlay augmentation: comparison of donor site morbidity and complications (2003) Clin Implant Dent Relat Res, 5, pp. 154-160Joshi, A., An investigation of post-operative morbidity following chin graft surgery (2004) Br Dent J, 196, pp. 215-218Block, M.S., Kent, J.N., Kallukaran, F.U., Thunthy, K., Weinberg, R., Bone maintenance 5 to 10 years after sinus grafting (1998) J Oral Maxillofac Surg, 56, pp. 706-71
Polymorphisms in fatty acid metabolism-related genes are associated with colorectal cancer risk
No full textColorectal cancer (CRC) is the third most common malignant tumor and the fourth leading cause of cancer death worldwide. The crucial role of fatty acids for a number of important biological processes suggests a more in-depth analysis of inter-individual differences in fatty acid metabolizing genes as contributing factor to colon carcinogenesis. We examined the association between genetic variability in 43 fatty acid metabolism-related genes and colorectal risk in 1225 CRC cases and 2032 controls participating in the European Prospective Investigation into Cancer and Nutrition study. Three hundred and ninety two single-nucleotide polymorphisms were selected using pairwise tagging with an r(2) cutoff of 0.8 and a minor allele frequency of > 5%. Conditional logistic regression models were used to estimate odds ratios and corresponding 95% confidence intervals. Haplotype analysis was performed using a generalized linear model framework. On the genotype level, hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), phospholipase A2 group VI (PLA2G6) and transient receptor potential vanilloid 3 were associated with higher risk for CRC, whereas prostaglandin E receptor 2 (PTGER2) was associated with lower CRC risk. A significant inverse association (P <0.006) was found for PTGER2 GGG haplotype, whereas HPGD AGGAG and PLA2G3 CT haplotypes were significantly (P <0.001 and P = 0.003, respectively) associated with higher risk of CRC. Based on these data, we present for the first time the association of HPGD variants with CRC risk. Our results support the key role of prostanoid signaling in colon carcinogenesis and suggest a relevance of genetic variation in fatty acid metabolism-related genes and CRC risk
Body Proportions In Children And Adolescents With Down's Syndrome
No full textThe present study aimed to evaluate the body proportions of sitting height and leg length in children and adolescents with Down's syndrome (DS). The sample consisted of 99 individuals with DS (40 girls with an average age of 11.45 ± 2.6 years and 59 boys with an average age of 12.07 ± 3.0 years). The following parameters were studied: chronological age, height, sitting height and leg length. The body proportions of each segment were calculated using body indices and the Phantom model. For the statistical analysis, the normality test and descriptive analyses of central tendency and dispersion were performed, and Student's t-test was used. For all treatments, the statistical software program SPSS version 13.0 was used, and a significance level of p < 0.05 was set. The body proportion of the upper and lower segments of children and adolescents with DS differed from those of the typical population in terms of leg length, whereas the seated height values of individuals with DS †were similar to those of individuals without DS.232198202Roizen, N.J., Patterson, D., Down's syndrome (2003) Lancet, 12 (361), pp. 1281-9Sugayama, S.M.M., Kim, C.A., Anormalidades Cromossômicas Chromosomal abnormalities In: Setian (2002) N. Endocrinologia Pediátrica - Aspectos físicos e metabólicos do recémnascido ao adolescente. São Paulo: Editora Sarvier, pp. 638-639Griffiths, A.J.F., Wessler, S.R., Lewontin, R.C., Gelbart, W., Introdução a Genética Introduction to genetics (2006) Guanabara Koogan, p. 534Licastro, F., Mariani, R.A., Faldella, G., Carpene, E., Guidicini, G., Rangoni, A., Immune endocrine status and coelic disease in children with Down's Syndrome: relationships with zinc and cognitive efficiency (2001) Brain Res Bull, 2 (55), pp. 313-17Coelho, C.R.Z., Loevy, H.T., Odontological aspects of Down's syndrome (1986) ARS Curandi Odontol, 3 (8), pp. 9-16Mugayar, L.R.F., Pacientes portadores de necessidades especiais: manual de odontologia e saúde oral [Patients with special needs: Manual of dentistry and oral health] (2000) São Paulo: Pancast, 13Cronk, C., Crocker, A.C., Pueschel, S.M., Shea, A.M., Zackai, E., Growth charts for children with Down syndrome: 1 month to 18 years of age (1988) Pediatrics, 1 (81), pp. 102-110Myrelid, A., Gustafsson, J., Ollars, B., Annerén, G., Growth charts for Down' syndrome from birth to 18 years of age (2002) Arch Dis Child., 2 (87), pp. 97-103Kimura, J., Tachibana, K., Imaizumi, K., Kurosawa, K., Kuroki, Y., Londitudinal growth and height velocity of Japanese children with Down's Syndrome (2003) Acta Paediatr, 9 (92), pp. 1039-1042Rarick, G.L., Seefeldt, V., Observations from Longitudinal Data on Growth in Stature and Sitting Height of Children with Down's Syndrome (1974) J Ment Defic Res, 1 (18), pp. 63-78Ross, W.D., Wilson, N.C., A stratagem for proportional growth assessment (1974) Acta Pediátrica, 1 (28), pp. 169-182De la Rosa, F.J.B., Rodriguez-añez, C.R., O estudo das características físicas do homem por meio da proporcionalidade [The study of the physical characteristics of men by means of proportionality] (2002) Rev Bras Cine Des Hum, 1 (4), pp. 53-66Guedes, D.T., Guedes, J.E.R.P., Manual prático para avaliação em Educação Física [Practical manual for evaluation in physical education] (2006) Editora Manole, pp. 153-4Jaswal, S., Jaswal, I.J.S., An anthropometric study of body size in Down syndrome (1981) Indian Journal of Pediatrics, 48 (1), pp. 81-84Hughes, P.C.R., Ribeiro, J., Hughes, I.A., Body proportions in Turner's Syndrome (1986) Archives of Disease in Childhood, 61, pp. 506-517Baldin, A.D., Armani, M.C.A., Morcillo, A.M., Lemos-Marini, S.H.V., Baptista, M.T.M., Maciel-Guerra, A.T., Guerra Júnior, G., Proporçñes corporais em um grupo de pacientes brasileiras com Síndrome de Turner [Body proportions in a group of Brazilian patients with Turner syndrome] (2005) Arq Bras Endocrinol Metab, 49 (4), pp. 529-535Arnell, H., Gustafsson, J., Ivarsson, S.A., Annerén, G., Growth and pubertal development in Down syndrome (1996) Acta Paediatr, 9, pp. 1102-6Annerén, G., Tuvemo, T., Carlsson-Skwirut, C., Lönnerholm, T., Bang, P., Sara, V.R., Gustafsson, J., Growth hormone treatment in young children with Down's Syndrome: effects on growth and psychomotor development (1999) Arch Dis Child, 80, pp. 334-338Gorla, J.I., Duarte, E., Costa, L.T., Fabia, F., Crescimento de crianças e adolescentes com Síndrome de Down - uma breve revisão de literature [Growth of children and adolescents with Down syndrome -a brief literature review] (2011) Rev Bras Cineantropom Desempenho Hum, 13 (3), pp. 230-23
In situ architecture of neuronal α-Synuclein inclusions
No full text© The Author(s) 2021. This manuscript version is made available under the CC-BY- 4.0 license http://creativecommons.org/licenses/by/4.0/. This document is the Published version of a Published Work that appeared in final form in Nature Communications. To access the final edited and published work see https://doi.org/10.1038/s41467-021-22108-0The molecular architecture of α-Synuclein (α-Syn) inclusions, pathognomonic of various neurodegenerative disorders, remains unclear. α-Syn inclusions were long thought to consist mainly of α-Syn fibrils, but recent reports pointed to intracellular membranes as the major
inclusion component. Here, we use cryo-electron tomography (cryo-ET) to image neuronal α-Syn inclusions in situ at molecular resolution. We show that inclusions seeded by α-Syn aggregates produced recombinantly or purified from patient brain consist of α-Syn fibrils crisscrossing a variety of cellular organelles. Using gold-labeled seeds, we find that aggregate
seeding is predominantly mediated by small α-Syn fibrils, from which cytoplasmic fibrils grow unidirectionally. Detailed analysis of membrane interactions revealed that α-Syn fibrils do not contact membranes directly, and that α-Syn does not drive membrane clustering. Altogether,
we conclusively demonstrate that neuronal α-Syn inclusions consist of α-Syn fibrils intermixed with membranous organelles, and illuminate the mechanism of aggregate seeding and cellular interaction
A construção do conhecimento pedagógico do conteúdo na docência em fisioterapia : um estudo de caso
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2015Este estudo de caso compõe parte da investigação da prática do docente fisioterapeuta experimentado (mais de 15 anos de atuação docente) que atua na formação do fisioterapeuta para a Atenção Primária à Saúde. O referencial teórico norteador escolhido foi o de Lee Shulman. Este autor coloca que o bom docente domina tanto o conhecimento do conteúdo quanto o conhecimento pedagógico, que unidos compõe o Conhecimento Pedagógico do Conteúdo que é expresso na prática do bom docente, comum a docentes experimentados. Nesta perspectiva esta investigação apresenta os resultados obtidos por meio de Entrevista Autobiográfica realizada no ano letivo de 2014 em Instituição de Ensino Superior Federal Pública. O objetivo foi conhecer os momentos que constituem a formação profissional do docente fisioterapeuta que atua na formação para a Atenção Primária à Saúde e sua relação com as Fontes do Conhecimento Pedagógico do Conteúdo. Com base na narrativa da participante do estudo de caso, os resultados foram organizados nas categorias: A prática que outorga a sabedoria, A formação para a prática docente, Formação no conteúdo da Atenção Primária à Saúde, Implicações da vida pessoal e familiar à vida profissional na docência, Reflexões sobre sua formação docente, modificações e enfrentamentos no percurso. A análise confirmou a presença da maioria das Fontes do Conhecimento Pedagógico do Conteúdo. Porém, foi identificada a ausência da fonte Formação acadêmica na disciplina a ensinar, o que revelou outras fontes como o autodidatismo e o compartilhamento de saberes com outros colegas docentes. Além destes resultados pode-se observar que essa metodologia e referencial teórico contribuem para a formação do próprio participante da pesquisa (re)significando sua experiência e prática.Abstract: This case study consists of the research of experienced physiotherapist teaching practice (over 15 years of teaching practice) that acts in the formation of the physiotherapist for Primary Care. The chosen guiding theoretical framework was to Lee Shulman. This author states that the good teacher dominates both knowledge of the content and pedagogical knowledge, which together make up the Pedagogical Content Knowledge that is expressed in the practice of teaching85good, common to experienced teachers. In this perspective this research presents the results obtained by Autobiographical Interview conducted in academic year 2014 Institution of Public Federal Higher Education. The objective was to know the moments that make up the professional education of physiotherapists teacher engaged in training for primary health care and its relationship to the Pedagogical Content Knowledge Sources. Based on the narrative of the case study participants, the results were organized in categories: Practice which gives wisdom, Training for teaching, training in the content of Primary Care Implications of personal and family life to professional life teaching, reflections on their teaching training, modifications and confrontations along the way. The analysis confirmed the presence of most of the Pedagogical Content Knowledge Sources. However, we identified the absence of Education source in the subject to be taught, which revealed other sources such as self-learning and sharing knowledge with other teacher's colleagues. In addition to these results, we note that this methodology and theoretical framework contribute to the formation of own research participant (re) meaning your experience and practice
Bioprospecção de macroalgas marinhas e plantas aquáticas para o controle da antracnose (Colletotrichum lindemuthianum) do feijoeiro (Phaseolus vulgaris L.): [dissertação]
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias. Programa de Pós-graduação em Recursos Genéticos VegetaisRealizou-se bioprospecção de espécies de macroalgas marinhas e plantas aquáticas com o objetivo de encontrar pelo menos um extrato eficiente para o controle da antracnose (Colletotrichum lindemuthianum) do feijoeiro. Para tanto, foram coletadas e identificadas 17 espécies de macroalgas marinhas: Acanthophora spicifera, Bostrychia sp., Bryothamnion seaforthii, Bryothamnion triquetrum, Centroceras clavulatum, Cheilosporum sagittatum, Codium isthmocladum, Codium sp., Enteromorpha sp., Enteromorpha lingulata, Gracilaria tepocensis, Hypnea spinella, Lithophyllum sp., Petalonia sp., Sargassum stenophyllum, Ulva lactuca, Ulva fasciata; e duas espécies de plantas aquáticas: Lemna sp. e Spartina juncea. Posteriormente, o material foi seco em estufa e os compostos foram extraídos em etanol e concentrados por evaporação. Os extratos foram testados in vitro, avaliando a influência sobre o índice de velocidade de crescimento micelial (IVCM) em meio de cultura, sobre a germinação de conídios e o padrão de germinação conidial (PGC) de C. lindemuthianum, em lâminas escavadas. Em ambos os testes, a concentração utilizada foi de 50 mg peso seco/ mL. Realizaram-se também testes em casa-devegetação onde os extratos foram testados por meio de pulverizações preventivas em plantas de feijoeiro cv. Uirapuru com posterior inoculação dessas plantas com uma suspensão de C. lindemuthianum (1,2x106 conídios/ mL). Para a verificação do efeito local e residual, plantas tratadas foram inoculadas 4 horas e 7 dias após o tratamento, respectivamente, e foram avaliadas as plantas inteiras. Para a verificação do efeito sistêmico, plantas tratadas foram inoculadas 7 dias após o tratamento e somente o trifólio não tratado foi avaliado. A severidade da antracnose foi avaliada aos 5 e 11 dias após inoculação. O extrato de H. spinella apresentou forte ação sobre o crescimento vegetativo de C. lindemuthianum, reduzindo o IVCM em 74% comparado à testemunha. Os extratos de Lemna sp. e S. stenophyllum inibiram a germinação de conídios de C. lindemuthianum em 100% e 99%, respectivamente. Nos testes in vivo, verificou-se que sob efeito local o extrato de B. seaforthii reduziu 35% a severidade da antracnose aos 11 d.a.i.. Embora sem apresentar efeito local, o extrato de Ulva fasciata reduziu 24% a severidade da antracnose aos 11 d.a.i. sob efeito residual e 42% a severidade da antracnose aos 5 d.a.i. sob efeito sistêmico. A indução de resistência foi considerada para explicar a redução de doença pelo extrato de Ulva fasciata. Dados de avaliações in vitro não correlacionaram com os dados obtidos nos experimentos com plantas. bioprospecting work was performed with species of marine macroalgae and aquatic plants, in order to screen at least an extract able to control the bean anthracnose. For that, it was collected and identified 17 marine macroalgae species, i.e. Acanthophora spicifera, Bostrychia sp., Bryothamnion seaforthii, Bryothamnion triquetrum, Centroceras clavulatum, Cheilosporum sagittatum, Codium isthmocladum, Codium sp., Enteromorpha sp., Enteromorpha lingulata, Gracilaria tepocensis, Hypnea spinella, Lithophyllum sp., Petalonia sp., Sargassum stenophyllum, Ulva lactuca, Ulva fasciata as well as two aquatic plant species, i.e. Lemna sp. and Spartina juncea. Thereafter, these species were dried in a chamber and, their compounds were extracted with ethanol and concentrated by solvent evaporating. The extracts were tested in vitro for evaluating the effect of them on the mycelial growth velocity index (IVCM) in culture medium and the conidial germination as well as the pattern of conidial germination (PGC) of C. lindemuthianum in well slides. The extract concentration used in both tests was always 50 mg dry wheight/ mL. Experiments were also carried out under greenhouse conditions where bean plants cv. Uirapuru were previously sprayed with the extracts and inoculated with a conidial suspension of C. lindemuthianum (1,2x106 conidia/ mL). To verify the presence of local effect and residual effect, treated plants were inoculated 4 hours and 7 days after treatment, respectively, and whole plants were evaluated. To investigate the systemic effect, treated plants were treated 7 days after treatment, but the disease was evaluated only on the non-treated uppermost three-leaflet leaf. Anthracnose severity was determined on 5th and 11th day after inoculation (dai). The extract of H. spinella presented a strong action towards the mycelial growth of C. lindemuthianum, reducing the IVCM by 74% when compared to the control. The extracts of Lemna sp. and S. stenophyllum inhibited the fungus conidial germination by 100% and 99%, respectively. In greenhouse tests the B. seaforthii revealed local effect, reducing the disease severity by 35% on the 11 dai. Although without showing local effect, the extract of Ulva fasciata reduced the anthracnose severity on the 11th dai by 24% in whole plants and on the 5th dai systemically by 42% as well. The induction of resistance was taken in consideration to explain the disease severity reduction by the extract of Ulva fasciata. In vitro data did not correlate with those obtained from greenhouse experiments
