124,669 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
REGULATION OF CHROMOSOME SEGREGATION BY CONSERVED PHOSPHATASE CDC14 AND KINASE CDC5
No full textThe faithful transmission of the replicated genome from the mother to the daughter cell requires the correct establishment of linkages between the duplicated chromosomes (sister chromatids) and their bi-orientation on the mitotic spindle. Chromosome segregation initiates only after each sisters pair is correctly aligned onto the microtubules emanating from the spindle poles. Next, Esp1-mediated cleavage of cohesin is required to trigger anaphase onset while the physical segregation of the separated sisters is next driven by spindle activity. However, this scenario appears to be more complicated involving additional factors driving the sister chromatid segregation process (i.e. the Top2-mediated resolution of replication catenates). In budding yeast, anaphase progression and exit from mitosis require the protein phosphatase Cdc14 whose activation relies on two consecutive protein pathways, the FEAR network and the MEN. As the polo-like kinase Cdc5 is a component of both pathways its activity is essential to Cdc14 release and in its absence Cdc14 is never released.
By combining loss-of-function alleles of Cdc5 and Cdc14 we obtained double mutant cells that had cohesin cleaved but still arrested with undivided nuclei and short bipolar spindles. Anaphase spindle elongation initiates quickly after cohesin removal (anaphase A) and then switches to a slower elongation rate (anaphase B) due to changes in spindle behaviour mediated by motor proteins and microtubule-associated enzymes. Although some residual cohesion between sister chromatids seems to contribute to the terminal phenotype of cdc14 cdc5 cells, our data indicate that anaphase B is the main mitotic defect of these cells.
We conclude that Cdc5 and Cdc14 are redundantly involved in activating spindle activity following cohesion resolution, suggesting the existence of a regulatory network that coordinates sister chromatid separation with spindle elongation after cohesin cleavage. Importantly, we identified the motor protein Cin8 as a (direct or indirect) target of Cdc5 in the regulation of spindle elongation
Pragmatic Case Studies as a Source of Unity in Applied Psychology
No full textTo unify or not to unify applied psychology: that is the question. In this article we review pendulum swings in the historical efforts to answer this question—from a comprehensive, positivist, “top-down,” deductive yes between the 1930s and the early 60s, to a postmodern no since then. A rationale and proposal for a limited, “bottom-up,” inductive yes in applied psychology is then presented, employing a case-based paradigm that integrates both positivist and postmodern themes and components. This paradigm is labeled “pragmatic psychology” and, its specific use of case studies, the “Pragmatic Case Study Method” (“PCS Method”). We call for the creation of peer-reviewed journal-databases of pragmatic case studies as a foundational source of unifying applied knowledge in our discipline. As one example, the potential of the PCS Method for unifying different angles of theoretical regard is illustrated in an area of applied psychology, psychotherapy, via the case of Mrs. B. The article then turns to the broader historical and epistemological arguments for the unifying nature of the PCS Method in both applied and basic psychology.Peer reviewe
Dr. Edwin Wright Collection: Author Unknown
No full textNotes - The author relates several short stories about his neighbours including Alex McDonell, homesteading and life around Meanook and Athabasca (1 page
Effects of organic fertilisation on ‘Valencia late’ orange bearing trees
No full textIn a study realised over a three year period on orange bearing trees (Citrus sinensis (L.) Osbeck) ‘Valencia late’, grafted on sour orange (C. aurantium L.), the effect of organic fertilisers (OF) on plant nutrition and performance was verified. In a randomized block experimental design, four treatments were compared, namely: mineral fertiliser (MF) treatment adopted as control, citrus byproduct compost (CB), poultry manure (PM) and livestock waste compost (LW). The trees, with the exception
of (MF) treatment, were organically grown since 1994 in the experimental farm of
CRA-ACM in Lentini, Sicily, and received the same N input every year. Significant differences for micronutrients (Fe, Mn, Zn) were noticed in leaf analyses, whereas no difference was found between treatments for leaf macronutrient content. The δ15N detected in leaves, proteins of pulp and amino acids of juice showed the lower level in MF, an intermediate value in CB and the highest level in animal derived fertilisers treatments (PM and LW). Fruit of the CB treatment showed values of total soluble solids and total acidity significantly lower than other treatments. Orange peel Chroma C* in CB and MF was higher than in PM and LW treatments. Discriminant analysis of the leaf and fruit analytical data set successfully separated treatments. First discriminant canonical function explains the 96,9% of the variability, with highly significant Wilks’ lambda. Cross validation classified correctly all MF and CB samples, whereas PM and LW in few cases were mixed up
Risposta dei bioindicatori della qualità del suolo alla diversa fertilizzazione di un aranceto nell’ Italia Meridionale
No full textLo scopo della ricerca è stato quello di valutare i cambiamenti indotti dalle diverse tipologie di fertilizzazione sui parametri chimici e biologici di un suolo. Il suolo dell’agro di Lentini (SR, Sicilia), coltivato ad arancio da oltre 50 anni, a partire dal 1995 secondo il metodo biologico , omogeneo per portinnesto e cultivar, è stato addizionato con 4 diversi tipi di fertilizzanti (pollina, minerale, compost da pastazzo e letame). Quattro profili di suolo, ciascuno per tipo di fertilizzazione, sono stati campionati e studiati secondo la sequenza degli orizzonti genetici. In totale 18 campioni orizzonte-specifici di suolo sono stati prelevati e sottoposti ad analisi per valutare il contenuto in C organico totale, estraibile e della biomassa microbica, N totale, ammoniacale e nitrico. L’attività della biomassa microbica è stata valutata determinando la quantità di CO2 emessa durante 30 giorni di incubazione a condizioni controllate. Inoltre, sono stati determinati gli acidi grassi dei fosfolipidi (PLFA), che comprendendo dei biomarkers specifici della biomassa batterica e fungina, hanno permesso di evidenziare variazioni della struttura delle comunità microbiche. Nel presente lavoro sono illustrati e spiegati i risultati della suddetta ricerca
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Cutaneous B-cell lymphomas: Update on diagnosis, risk-stratification, and management
No full textPCBCLs are a group of Non-Hodgkin's B-cell lymphomas originating in and usually confined to the skin, representing approximately one fourth of primary cutaneous lymphomas (PCL). Their current classification system has been the result of the joint World Health Organization (WHO) European Organization for Research and Treatment of Cancer (EORTC) consensus in 2018. To date, several types of PCBCLs have been described in the scientific literature, with different clinical presentation and prognosis. Primary cutaneous follicle-center lymphoma (PCFCL) and primary cutaneous marginal zone lymphoma (PCMZL) are the most common forms, with a typical indolent course. On the contrary, primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL, LT) is less common, yet more aggressive, with a reported 5-year overall survival of approximatively 50%. In this review, we outline the PCBCLs defining diagnostic criteria, report the features of the less common subtypes and summarize the noteworthy therapeutical options currently available in this field. (c) 2022 Elsevier Masson SAS. All rights reserved
Measurement of the ratio of branching fractions B(B0→K∗0γ )/B(B0s→φγ ) and the directCP asymmetry inB 0→K∗0γ
No full textThe ratio of branching fractions of the radiative B decays B0→K⁎0γ and B0s→ϕγ has been measured using an integrated luminosity of 1.0 fb−1 of pp collision data collected by the LHCb experiment at a centre-of-mass energy of s√=7TeV. The value obtained is
B(B0→K⁎0γ)B(B0s→ϕγ)=1.23±0.06(stat.)±0.04(syst.)±0.10(fs/fd),
where the first uncertainty is statistical, the second is the experimental systematic uncertainty and the third is associated with the ratio of fragmentation fractions fs/fd. Using the world average value for B(B0→K⁎0γ), the branching fraction B(B0s→ϕγ) is measured to be (3.5±0.4)×10−5.
The direct CP asymmetry in B0→K⁎0γ decays has also been measured with the same data and found to be
ACP(B0→K⁎0γ)=(0.8±1.7(stat.)±0.9(syst.))%.
Both measurements are the most precise to date and are in agreement with the previous experimental results and theoretical expectations
- …
