59 research outputs found

    HLA and ABO gene polymorphisms in the Indonesian people

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    Starfruit Leaves as Glucose Absorption Inhibitor in Mice’s Small Intestinal Epithelial Cells

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    Background: Starfruit (Averrhoa carambola) leaves contain flavone derivatives that exhibit anti-hyperglycemic effects. This study aims to determine the effect of starfruit leaves in reducing glucose absorption in intestinal epithelial cells of mice. Methods: This study was done by performing perfusion on the small intestines of mice. The mice that were used in this study were divided into four groups. The control group was given glucose solution without infused starfruit leaves whereas, the remaining 3 groups were given 3 mmol (540 mg/dL) glucose solution with infused starfruit leaves of varying concentrations; 200, 400, and 600 mg/kg. Samples were collected at 0, 15th, 30th, 45th, and 60th minute. The sample was tested for glucose levels using spectrophotometry. Results: Test of significance showed a significant difference between the control group and the test group with p < 0.05. Conclusions: Starfruit leaves have a reduction effect towards glucose absorption in the small intestines in Wistar strains where the group using 600 mg/kg of infused starfruit leaves have the most significant effect as compared to other groups

    Factors Affecting Mortality in Adult Tetanus Patients

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    Background: Tetanus is a devastating disease that is associated with high mortality. The aim of this study was to analyze the prognostic factors that were associated with high mortality in tetanus. Methods: This was an analytical study and the data was collected retrospectively from 1 January 2010–31October 2012 in the Department of Neurology, Dr. Hasan Sadikin General Hospital. Results: Out of hundred thirty two cases only 87 cases of tetanus patient have complete medical records. There were 54 male and 33 female. The age range was 35-49 years old. Mortality rate was high (32.18%). The most frequent wound site is extremities (85.07 %). The absence of post-injury tetanus vaccination was 75.86%, period of onset <48 hours was 67.82% and the use of mechanical ventilation and tracheostomy 36.07%. Mortality was significantly associated with an incubation period <7 days (p<0.05), presence of fever (p <0.05), co morbidity of autonomic storm (p<0.01), and the severity of the disease by grade 5 (p<0.05). Conclusions: Factors affecting the mortality in adult tetanus patients were significant for incubation period, fever, co morbidity and severity of the disease by grade

    Direct Current Motor Rotation Setting With PLC

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    42 Halamankemajuan teknologi dewasa ini telah menghasilkan berbagai jenis alat alat yang canggih, namun di dalam pengoperasiannya masih menggunakan tenaga manusia seluruhnya. Untuk itu penulis mencoba membuat suatu rancangan yang dapat mempermudah proses pengoperasian pengontrolan alat industri yang memakai aplikasi komputer. Dalam penelitian ini penulis mencoba membahas suatu alat yang dapat mengontrol jalannya operasi suatu sistem secara otomatis dan berkesinambungan. Alat yang dimaksud adalah programmable logic control (plc) dimana dalam tulisan ini digunakan untuk mengatur kecepatan putaran motor ams searah (dc). Kelebihan alat tersebut adalah dapat di program berulang kali dan dapat dijadikan alat pengendali yang dapat dirancang khusus untuk penggunaan di industri karena plc telah di rancang sederoikian rupa sehingga lebih mudah ditempatkan dan pemrogramannya lebih sederhana . Program yang digunakan dalam plc adalah diagram ladder (doagram tangga). Today's technological advances have produced various types of sophisticated tools, but in operation they still use entirely human power. For this reason, the author tries to make a design that can simplify the process of controlling industrial equipment using computer applications. In this study the author tries to discuss a tool that can control the operation of a system automatically and continuously. The tool in question is a programmable logic control (plc) which in this paper is used to regulate the rotational speed of a DC motor. The advantage of this tool is that it can be programmed repeatedly and can be used as a controller that can be specially designed for industrial use because the PLC has been designed in such a way that it is easier to place and the programming is simpler. The program used in PLC is a ladder diagram

    Metode Cepat Identifikasi Flavonoid dari Daun Ocimum sanctum L. (Selasih)

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    A plant’s effectiveness as a herbal drug comes from its chemical content such as flavonoids. Flavonoids are useful for human body health. Therefore flavonoids content can be used as a marker from the usefulness of a plant, and rapid identification method of flavonoid is needed. The objective of the research was to get a rapid method of flavonoid content identification from Ocimum sanctum. The extraction, isolation and identification of flavonoids from Ocimum sanctum leaves has been done at Medical Chemistry laboratory Faculty of Medicine Universitas Padjadjaran in 2005. Flavonoids were extracted continually by 95% ethanol, were isolated with paper chromatography/cellulose TLC and 2% acetic acid, then continued with elucidation reagents: n-butanol–acetic acid–water, chloroform–acetic acid–water, forestall, 5%, 15%, 35% and 50% acetic acids. Flavonoids were identified with diagnostic reagents and ultraviolet light. Isolation with 2% and 35% acetic acids respectively gave two spots of flavonoids as flavon, FOAc-1 had Rf=0.69 and FOAc-2 had Rf=0.57. The other elucidation reagents gave one spot of flavonoid. In conclusion, isolation with 2% and 35% acetic acids respectively and identification with diagnostic reagent and ultraviolet light is a rapid method for identification of flavonoids content in Ocimum sanctu

    Perancangan dan Pembuatan Catu Daya Digital Berbasis Mikrokontroler AT89S52

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    18 HalamanSumber energi merupakan suatu faktor yang sangat dibutuhkan dalam menjalankan suatu sistem. Salah satunya dalam sistem elektronika yang menggunakan catu daya sebagai salah satu sumber energinya. Tidak semua peralatan elektronika di desain dengan internal catu daya, sebagian dari peralatan elektronika masih memerlukan ekstemal catu daya. Catu daya yang ada dipasaran masih membingungkan masyarakat dalam pemakaiannya sehingga sering terjadi kesalahan dalam pemberian tegangan ke suatu beban. Oleh karena itu penulis memiliki ide merancang dan membuat catu daya Digital Otomatis dan manual. Dengan dasar ini masyarakat akan lebih mudah menggunakan tegangan DC sebagai sumber tegangan, karena catu daya ini dapat menentukan besar tegangan outputnya sendiri. Dengan kata lain catu daya ini bersifat otomatis yang membuatnya beda dari catu daya yang ada di pasaran. Energy source is a factor that very needed to operate a system. One of the useful is in the electronic system that use power supply as one of the energy. Much of the electronic tools do not design with internal power supply, most of them still need external power supply. Power supply that sells in market still make most people confuse to use it, so many mistakes that happen when the user going to load the voltage. Because of that , author have an idea to design and build a Digital Power Supply . With this basic, people can be easily to use DC voltage as voltage source, because this power supply can decide by itself how many voltage will use. With the other words, this power supply have automatic character that make it different from other power supply in market

    Blunted Expression of PPARa in Mice with FABP-4 and -5 Deficiency under Acute Cold Exposure

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    Brown Adipose Tissue (BAT) is a nonshivering thermogenesis organ during cold exposure. Peroxisomal proliferator activated receptor alpha (PPARa) is the member of the nuclear hormone receptor superfamily and primarily expressed in BAT and liver. PPARa is coordinated with uncoupling protein 1 (UCP1) to regulate fatty acid metabolism in BAT. Fatty acid binding protein (FABP)-4 and-5 play role in adaptive response under fasting and cold exposure. The purpose of this study was to investigate the expression of PPARa in mice with FABP4/5 deficiency (DKO). Wildtype (WT) and DKO mice were exposed to cold for 2 hours under fed or 20 hours-fasted conditions. BAT was collected and further mRNA level of PPARa was examined using quantitative real-time PCR. As the result, PPARa gene expression in WT mice were increased 50% and 100% in fed and fasted condition respectively after cold exposure. There was no alteration in PPARa expression in  BAT of DKO mice. As conclusion, The functional FABP-4 and -5 are necessary to modulate PPARa gene expression in Brown Adipose Tissue under acute cold exposure  Keywords: Acute cold exposure; FABP4; FABP5; Fasting  PPARa</jats:p

    KONSEP KELUARGA MAß╣óLAß©ñAH DALAM PERSPEKTIF QIRAÔÇÖAH MUBADALAH DAN RELEVANSINYA DENGAN KETAHANAN KELUARGA DI MASA PANDEMI COVID-19

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    This article discusses the concept of the maß╣úlaß©Ñah family in the perspective of mubadalah and its relevance to family resilience during the Covid-19 pandemic. The maß╣úlaß©Ñah family is a family whose members provide each other with primary needs that include physical and mental needs, and each others give rights and obligations. This paper is a literature research, with the descriptive-qualitative as method research and qiraÔÇÖah mubadalah as the approach. The results showed that the concept of maß╣úlaß©Ñah family in the perspective of qiraÔÇÖah mubadalah is that in principle it prioritizes the concept of mufaÔÇÖalah (kesalingan), meaning that there are no superior and no inferior parties in the family. In this case the maß╣úlaß©Ñah family indicators that can be displayed are at least several principles, namely the zawaj principle (prinsip saling berpasangan), the muÔÇÖadalah Principle (prinsip keadilan), the muwazanah principle (prinsip keseimbangan), the muÔÇÖawanah principle (prinsip saling menolong), the Principle of musyawarah, the Principle of taradhin min huma┬á (prinsip kerelaaan), and the Principle of muÔÇÖasyarah bil maÔÇÖruf (prinsip saling berkomunikasi/bergaul dengan baik). The author can conclude that the concept of the maß╣úlaß©Ñah family in the framework of mubadalah is that it has quite significant relevance if it is applied by every family, especially in the current Covid-19 pandemic

    PROFIL MAHASISWA DENGAN TUGAS GANDA KULIAH DAN BEKERJA

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    Students have important roles in realizing the ideals of national development, meanwhile universities are educational institutions that are formally assigned the task and responsibility of preparing students in accordance with the goals of higher educators. The purpose of this research is to find out the extent to which students who study while working delay while completing their thesis. And also to know the negative impact of procrastination essay. The research conducted by this author is a qualitative descriptive study. In the process of collecting data, the author uses the method of observation, interviews, and documentation. Furthermore, for data analysis, the author uses qualitative descriptive, namely data in the form of writing or writing from the informants or respondents being studied in order to fully describe the phenomena in the field. Keywords: student profiles, dual assignments, lectures, work
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