22 research outputs found
Thesis : Efektivitas Lekodeplesi Dalam Meningkatkan Keamanan Darah Donor Terhadap Infeksi CMV
No full textSampai saat ini di indonesia belum diketahui prevalensi seropositif CMV pada darah donor sehingga belum dilakukan uji saring terhadap antibodi CMV dan analisis DNA CMV pada PRC leukodepleted secara rutin untuk keamanan darah donor. Tujuan penelitian ini adalah mendapatkan informasi efektifitas teknik leukodeplesi PRC terhadap deteksi DNA CMV, mendapatkan informasi mengenai prevalensi PRC dengan antibodi lgG CMV positif dan mendapatkan informasi mengenai prevalensi DNA CMV positif pada PRC non-leukodepleted serta PRC leukodepleted di UTD PMI Provinsi DKI Jakarta. Metode yang digunakan desain potong lintang (cross sectional) dengan jumlah sampel 113 darah donor yang telah memenuhi kriteria inklusi. Uji saring antibodi igG CMV menggunakan metode indirect chemiluminescence immunoassay (ChLIA) dengan alat liason XL 10050 Chemiluminescence Analyzer dan analisis DNA CMV menggunakan metode qPCR untuk deteksi UL54 CMV dengan alat Roche Light Cycler 480 II. Hasil penelitian menunjukkan prevalensi igG CMV positf sebanyak 111 sampel (98,23%) dan igG CMV negatif sebaynyak 2 sampel (1,77%). Prevalensi DNA CMV positif pada PRC non leukodepleted adalah 1 sampel (0,88%) dan ORC leukodepleted adalah 0 sampel (0%). Kesimpulan penelitian ini, PRC leukodepleted efektif dalam meningkatkan keamanan darah donor terhadap infeksi CMV.xvii+91 hlm; 21x3
Metaphors in Mata Najwa Podcast Episode: “Eklusif, Ganjar Pranowo dan Piala Dunia” | Mata Najwa
Get PDFThis research discusses the use of metaphor features in the Podcast Najwa Shihab Episode “Eklusif: Ganjar Pranowo dan Piala Dunia” | Mata Najwa. This podcast is one of the contents of Najwa Sihab's Youtube channel which is the source of data in this study. The purpose of the research is to analyze the characteristics of metaphors used and their relationship with power. This research was conducted using Fairclough's (1992) critical discourse research approach, which views language as a means of power. The research method used was descriptive qualitative. Through this research, the author found six metaphorical expressions from the podcast episode " Eklusif: Ganjar Pranowo dan Piala Dunia” | Mata Najwa. The results of this study show that language not only plays a central role in human life, but language is also created as a tool to control something, change something or make something happen. Other results show that the discourse and communication patterns between Najwa Shihab and Ganjar Pranowo in the podcast exemplify the exercise of power that directly influences people's opinions and behavior in responding to the government's stance of canceling the 2023 World Cup in Indonesia
Analisis Pemanfaatan Media Sosial Twitter oleh Ganjar Pranowo dan Ridwan Kamil
No full textPelayanan publik adalah suatu kegiatan pemenuhan kebutuhan masyarakat dalam bentuk jasa maupun barang, namun saat ini buruknya pelayanan publik yang dirasakan masyarakat adalah pelayanan yang berbelit-belit, keterampilan pelayan publik yang kurang profesional, serta waktu pelayanan yang kurang efektif dan efisien. Permasalahan ini muncul dalam rangka untuk memberikan evaluasi kepada pelayan publik supaya lebih baik. Pelayan publik dituntut dapat menciptakan suatu ide atau inovasi pelayanan supaya kepuasan suatu masyarakat dapat terjamin. Media sosial menjadi solutif-alternative yang sangat berperan penting untuk optimalisasi sebuah sistem kerja pemerintah, salah satunya melalui media sosial twitter. Tujuan penelitian ini adalah untuk mendeskripsikan secara akademik dan ilmiah tentang pemanfaatan media sosial twitter dalam birokrasi pemerintahan sebagai upaya peningkatan pelayanan prima dengan berbagai informasi peristiwa yang penulis dapatkan. Metode penelitian ini menggunakan pendekatan kualitatif-deskriptif, sedangkan teknik analisis yang digunakan adalah analisis isi (content analysis) yang memuat metode induksi, deduksi, dan komparasi. Objek penelitian ini adalah media sosial akun twitter @ganjarPranowo dan akun twitter @ridwanKamil sebagai akun twitter resmi kepemilikan Ganjar Pranowo dan Ridwan Kamil. Hasil penelitian menunjukkan pemanfaatan media sosial twitter dalam birokrasi pemerintahan Ganjar Pranowo dan Ridwan Kamil sebagai upaya peningkatan pelayanan prima sudah memenuhi aspek variabel teori pelayanan prima. Dalam mewujudkan pelayanan prima melalui media sosial twitter telah menerapkan standar: kemampuan (ability), sikap (attitude), penampilan (appearance), perhatian (attention), tindakan (action), dan tanggung jawab (accountability). Dengan adanya media sosial twitter ini pemerintah menjadi lebih mudah untuk mengakses suatu informasi yang timbul di masyarakat, sehingga interaksi masyarakat dengan pemerintah menjadi mudah dan efektif. AbstractPublic service is an activity to meet the needs of the community in the form of services and goods, but currently the poor public services that are felt by the community are convoluted services, the skills of public servants who are less professional, and service time that is less effective and efficient. This problem arises in order to provide an evaluation to public servants to be better. Public servants are required to create an idea or service innovation so that the satisfaction of a community can be guaranteed. So, social media becomes a solutive alternative that plays an important role in optimizing a government work system, one of which is through social media Twitter. The purpose of this study is to describe academically and scientifically about the use of social media Twitter in the government bureaucracy as an effort to improve excellent service with various information events that the author gets. This research method uses a qualitative-descriptive approach, while the analytical technique used is content analysis which contains the methods of induction, deduction, and comparison. The object of this research is the social media account @ganjarPranowo and @ridwanKamil twitter account as the official twitter account of Ganjar Pranowo and Ridwan Kamil. The results showed the use of social media Twitter in the government bureaucracy of Ganjar Pranowo and Ridwan Kamil as an effort to improve excellent service had fulfilled variable aspects of excellent service theory. In realizing excellent service through social media, Twitter has implemented standards: ability, attitude, appearance, attention, action and accountability. With the existence of Twitter social media, the government becomes easier to access information that arises in the community, so that community interaction with the government becomes easy and effective
Trend Komunikasi Politik di Media Sosial
Get PDFCommunication is an activity that cannot be separated from human life. Based on its form, there is interpersonal communication, small group communication, public communication, organizational communication and mass communication. Based on the context, there are several types of communication, such as business communication, health communication, intercultural communication, family communication and also political communication. Basically communication is a relationship between humans in order to achieve mutual understanding (mutual understanding). To explain about ganjar pranowo's political communication through Instagram social media, the author uses a descriptive method with a qualitative approach. With this method the researcher tries to describe, analyze, and build meaning about political communication in the current era. Ganjar Pranowo is a political figure who is very active on social media and often uses social media to communicate with his people. Ganjar Pranowo is well-known on social media for his accomplishments in advancing Central Java, and he also enjoys being involved in society both virtually and in person. The image of a politician must be effective and channeled to be effective. Social media is a popular media used and followed by many people. This has the potential to change public opinion in a number of ways. Ganjar Pranowo is a political figure who is very active on social media and often uses social media to communicate with his people
THE INFLUENCE OF BLOOD VOLUME AND STORAGE DURATION ON THE ERYTHROCYTE SEDIMENTATION RATE (ESR) VALUE USING THE WESTERGREN METHOD
Get PDFBackground: Hematological examination is conducted to determine the condition of blood and its components, which are used to establish a diagnosis, support a diagnosis, make a differential diagnosis, monitor disease progression, assess the severity of an illness, and determine the initial prognosis of a disease. Phlebotomy procedures in the pre-analytical stage are not always successful and sometimes encounter failure. Inappropriate anticoagulant administration can lead to erroneous hematological examination results, including Erythrocyte Sedimentation Rate (ESR) examination results. Purpose: This research aims to examine the influence of blood volume and storage duration on the Erythrocyte Sedimentation Rate (ESR) value using the Westergren method. Method: The Westergren method utilizes 5 venous blood samples with a ratio of blood volume to 3.8% anticoagulant at 4 : 1, 3 : 1, and 2 : 1, with sample storage durations of 0 and 3 hours at room temperature. Result: The average ESR values with a ratio of 4 : 1, at 0 hours, were 5.20 mm/hour and at 3 hours were 3.60 mm/hour. The average ESR values with a ratio of 3 : 1, at 0 hours, were 6.20 mm/hour and at 3 hours were 4.40 mm/hour. The average ESR values with a ratio of 2 : 1, at 0 hours, were 7.60 mm/hour and at 3 hours were 5.60 mm/hour. Conclusion: There is a significant influence of blood volume (p-value < 0.05) and storage duration (p-value = 0.05) on the Erythrocyte Sedimentation Rate (ESR) value using the Westergren method
Pengaruh Jenis Antikoagulan dan Variasi Konsentrasi Suspensi Tes Sel ABO terhadap Hasil Pemeriksaan Serum Grouping Metode Tabung
Get PDFPemeriksaan golongan darah adalah rangkaian yang dilakukan sebelum transfusi untuk menguji kecocokan darah pasien dan donor. Pemeriksaan golongan darah ABO mencakup cell grouping dan serum grouping dengan gold standarnya adalah metode tabung. EDTA adalah antikoagulan yang biasa digunakan, tetapi sitrat juga bisa digunakan untuk pemeriksaan golongan darah. Salah satu faktor yang bisa memengaruhi pemeriksaan serum grouping adalah konsentrasi sel uji. Tujuan penelitian ini adalah untuk mengetahui pengaruh jenis antikoagulan K2EDTA dan Na Sitrat 3,8% dan variasi konsentrasi supensi tes sel ABO 1%, 3%, dan 5% terhadap hasil pemeriksaan serum grouping metode tabung. Jenis penelitian ini adalah eksperimen semu dengan 5 kali pengulangan. Data hasil penelitian diolah menggunakan uji Friedman dan dilanjutkan dengan uji Wilcoxon. Hasil uji Friedman terhadap pengaruh jenis antikoagulan diperoleh nilai signifikan 0,002 yang berarti terdapat pengaruh jenis antikoagulan K2EDTA dan Na Sitrat 3,8% terhadap hasil pemeriksaan serum grouping metode tabung. Hasil uji Friedman dan uji Wilcoxon terhadap variasi konsentrasi diperoleh nilai signifikan 0,002 dan 0,004 yang berarti terdapat pengaruh variasi konsentrasi suspensi tes sel ABO 1%, 3%, dan 5% terhadap hasil pemeriksaan serum grouping metode tabung. Derajat aglutinasi pada sel uji 1% dengan hasil positif 2, sedangkan 3% dan 5% pada aglutinasi positif 3 atau positif 4
Pengaruh Suhu dan Lama Simpan Washed Red Cell Terhadap Nilai Fragilitas Osmotik Metode Spektrofotometri
No full textWashed Red Cell adalah produk darah yang diperoleh dari proses pencucian Packed Red Cell, di mana zat aditifnya dihilangkan, sehingga lebih mudah mengalami hemolisis. Hemolisis saat penyimpanan bisa dipicu oleh faktor suhu dan lama penyimpanan. Penelitian ini ditujukan guna mengkaji pengaruh suhu serta lama penyimpanan terhadap tingkat fragilitas osmotik pada Washed Red Cell menggunakan metode spektrofotometri. Penelitian ini menggunakan rancangan kuasi-eksperimen, dengan satu unit kantong Washed Red Cell bergolongan darah O Rh+ yang ditempatkan pada kondisi suhu lemari pendingin dan suhu lingkungan selama 0, 4, 7, serta 10 jam. Hasil telaah deskriptif menunjukkan adanya kenaikan tingkat fragilitas osmotik pada seluruh kelompok perlakuan. Uji Friedman menunjukkan bahwa suhu penyimpanan refrigerator dengan ruang dan durasi penyimpanan (0, 4, 7, dan 10 jam) berpengaruh signifikan pada nilai fragilitas osmotik, dengan nilai signifikansi kurang dari 0,001 (P<0,05). Uji Wilcoxon juga mengonfirmasi adanya pengaruh lama penyimpanan, di mana sampel yang disimpan segera berbeda signifikan dengan yang ditunda selama 4, 7, dan 10 jam, dengan nilai signifikansi tidak melebihi 0,001 (P<0,05). Selain itu, uji Spearman menunjukkan hubungan yang kuat antara suhu penyimpanan dan lama penyimpanan dengan nilai fragilitas osmotik, dengan nilai signifikansi kurang dari 0,001 (P<0,05). Hubungan ini bersifat positif, ini berarti makin tingginya suhu dan makin lamanya waktu penyimpanan, maka nilai fragilitas osmotik pun akan semakin meningkat
Prevalensi Antibodi IgG dan DNA Cytomegalovirus pada darah donor di unit transfusi darah Provinsi DKI Jakarta
Get PDFIndonesia has not conduct regular screening test of CMV infection due to the lack of seropositive prevelance data information. However, seronegative CMV results is not an indicator of safe blood for transfusion, so that another test that serves as confirmation test for CMV DNA is required. The aim of this study is to obtain prevalence data of CMV IgG antibody positive, the prevalence of CMV DNA positive and to determine the effect of CMV IgG titers against CMV DNA in blood donors in UTD PMI DKI Jakarta. Cross-sectional method was used to test 113 blood donor samples which have met inclusion criteria. Screening for CMV IgG antibody was held using indirect method chemiluminescence immunoassay (ChLIA) by Liason® XL 10050 Chemiluminescence Analyzer and CMV DNA analysis using qPCR method for the detection of CMV UL 54 with a tool Roche Light Cycler 480 II. Results indicate positive prevalence of IgG CMV in 111 samples (98.23%), and negative CMV IgG in 2 samples (1.77%). Prevalence of CMV DNA positive donors is one sample (0.88%), 112 negative CMV DNA samples (99.12%) and Fisher's test results {P (0.982)> α (0.05)} showed no significant association between CMV IgG status with CMV DNA. CONCLUSIONS: UTD DKI Jakarta has a high prevalence of CMV IgG with low prevalence of CMV DNA
MODERNISASI DAN TERBENTUKNYA GAYA HIDUP ELIT EROPA DI BRAGAWEG (1894-1949)
No full textThis study describes the Bragaweg changes from 1894 to 1949. In addition, this study describes the form of European-style activity in Braga Street that represents the modern nuances of the colonial period. The historical method is used to construct the Braga story. To support the analysis of this study, the author uses the concept of modernization of Lawrence V. Stockman. He stated that modernization does not create something new but accept something new from another nation or other developed country. At first the European elite tried to adapt, then seek the formation of a typical European life in the colony. Bragaweg is a picture of the success of the European elit. The Bragaweg transformation represents economic growth in the region; From the emergence of staple stores to the rise of luxury and industrial goods stores. Modern impression is seen from the lifestyle practiced by the European elite and the full range of facilities and technology in the Bragaweg region. In the war of independence, the sparkling atmosphere of Europe was dimmed and replaced by the atmosphere of war.Keywords: Bragaweg, modern, life style, European elite.</jats:p
Persistence of Antibody Response Against SARS-CoV-2 After Vaccination
No full textSARS-CoV-2 is the causative agent of the disease known as COVID-19. COVID-19 is spreading very fast around the world. One of the immune responses that play a role in against SARS-CoV-2 infection is the production of antibodies, which is 3 weeks after infection. Where within 3 weeks after infection, antibodies will be produced against RBD and the S1 and S2 domains in glycoprotein S and nucleocapsid protein N. The ability of an antibody to inhibit viral infection is determined by its level or titer. This study aims to determine the description of antibody levels against SARS-CoV-2 after vaccination. This type of research is descriptive research. Measurement of antibody levels for SRBD SARS-CoV-2 was carried out using the CLIA method using the MAGLUMI tool. Of the 30 respondents, 23 people had received the third vaccine. The results of this study showed that the average level of SRBD antibodies against SARS-CoV-2 in respondents with 2 doses of vaccine (1.063,786 BAU/mL) was higher than in respondents with 3 doses of vaccine (535.651 BAU/mL). Vaccine intervals of more than 6 months (908.338 BAU/mL) have higher antibody levels than respondents with vaccine intervals of 1-6 months (228.006 BAU/mL). The conclusion of this study is the highest antibody titers are produced >6 months after vaccination, antibody titers are still detectable after 12 months of vaccination, and for further research, it can be measured antibody levels against SARS-CoV-2 from people who have got vaccination for a duration of 2 years or more
