155,953 research outputs found

    The Merrifield-Simmons Index and Hosoya Index of C(n,k,λ) Graphs

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    The Merrifield-Simmons index i(G) of a graph G is defined as the number of subsets of the vertex set, in which any two vertices are nonadjacent, that is, the number of independent vertex sets of G The Hosoya index z(G) of a graph G is defined as the total number of independent edge subsets, that is, the total number of its matchings. By C(n,k,λ) we denote the set of graphs with n vertices, k cycles, the length of every cycle is λ, and all the edges not on the cycles are pendant edges which are attached to the same vertex. In this paper, we investigate the Merrifield-Simmons index i(G) and the Hosoya index z(G) for a graph G in C(n,k,λ)

    An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy

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    Current knowledge of the structural changes taking place during clathrin-mediated endocytosis is largely based on electron microscopy images of fixed preparations and x-ray crystallography data of purified proteins. In this paper, we describe a study of clathrin-coated pit dynamics in living cells using ion conductance microscopy to directly image the changes in pit shape, combined with simultaneous confocal microscopy to follow molecule-specific fluorescence. We find that 70% of pits closed with the formation of a protrusion that grew on one side of the pit, covered the entire pit, and then disappeared together with pit-associated clathrin-enhanced green fluorescent protein (EGFP) and actin-binding protein-EGFP (Abp1-EGFP) fluorescence. This was in contrast to conventionally closing pits that closed and cleaved from flat membrane sheets and lacked accompanying Abp1-EGFP fluorescence. Scission of both types of pits was found to be dynamin-2 dependent. This technique now enables direct spatial and temporal correlation between functional molecule-specific fluorescence and structural information to follow key biological processes at cell surfaces

    O. A. C. Review Volume XLVI Issue 5, February 1934

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    The focus of this issue is the preparation for College Royal and recognizing its tenth anniversary. This month's agricultural article is a report from the Dominion Parasite Laboratory on the biological control of pests. Other articles provide an account of the activities of a stage manager and the development of the field of home economics at Macdonald College in Quebec. Campus news addresses the success of the 1934 Conversazione, the commemorating of the sixtieth anniversary of the founding of O. A. C., the attendance at the Canadian Author Lecture, and the successful productions of "The Apple Cart" and "Iolanthe". The Macdonald Institute column comments on the Conversat and women's athletics activities in basketball and the rifle club. The Alumni Record supplies alumni updates.EditorialTen Years of the RoyalRamblings on the RoyalBlame it on the stage managerBiological control of insect pests in CanadaNot for girls onlyCollege lifeLiterary sectionO. A. C. sportsfolioAlumni recordMacdonald newsLetters to the editoradvertisin

    Cacti with the maximum Merrifield–Simmons index and given number of cut edges

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    AbstractThe Merrifield–Simmons index of a graph G, denoted by i(G), is defined to be the total number of its independent sets, including the empty set. A graph G is called a cactus if each block of G is either an edge or a cycle. Denote by C(n,k) the set of connected cacti possessing n vertices and k cut edges. In this work, we shall characterize the cacti with the maximum Merrifield–Simmons index among all graphs in C(n,k) for all possible values of k

    O. A. C. Review Volume XXXVI Issue 12, August 1924

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    This slim summer issue contains the address given by the agricultural section of the British Association for the Advancement of Science, and a report on the visit of this association to the O. A. C. Other articles include instructions on increasing strawberry production and a biography of the author John Masefield. The editorial comments on Rhodes Scholars. The Alumni column provides an update of alumni activities. This issue does not contain a Macdonald column.JoyPresent-day problems in crop productionAfter the strawberry harvestJohn MasefieldVisit of the Agricultural Section of the British Association for the Advancement of ScienceEditorialCollege lifeAlumniadvertisin

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV

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    The prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region

    The Thursday Murder Club: Launching a megabrand author - a publishing case study

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    In 2020, the Christmas book charts in the UK made headlines: Barack Obama’s eagerly awaited autobiography, The Promised Land, was beaten to the top spot by The Thursday Murder Club by Richard Osman, a debut cosy crime novel set in a retirement village. Not only did Osman’s book beat the former US president’s expected bestseller, it also broke records, becoming the fastest-selling debut crime novel of all time. Although Osman has a certain level of fame in the UK from his TV appearances on shows such as Pointless, his celebrity status does not entirely explain the novel’s huge sales. This article tracks the acquisition, publication, and promotion journey of The Thursday Murder Club in order to understand the industry and cultural context of its success and to interrogate the role of celebrity in the creation of author brands. The findings suggest that the unexpected scale of the success of the book owed to a number of factors, including in-depth editing by the novel’s agent, editor, and author to tighten up the plot, an extensive and strategic promotional campaign, the pandemic (which drove interest in the book’s genre and themes), and the quality of the writing. We find that the book’s success was accentuated by Osman’s celebrity status rather than being entirely reliant on it. This research adds to the growing scholarship on celebrity authorship by means of an in-depth case study and provides insight into the processes behind publishing a ‘celebrity’ book and launching a megabrand author

    A Theme Analysis of Experiences Reported by Adult Children of Alcoholics in Online Support Forums

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    Growing up with an alcoholic parent can have a lasting effect on children and contribute to a variety of challenging outcomes in adulthood. This study identified the various experiences that adult children of alcoholics discuss with their peers in online support groups. Trained coders conducted a thematic analysis of 504 message board posts collected over a period of 60 days from three different online support groups to identify issues that children of alcoholics face in adulthood. Seven themes emerged from the analysis: a) empowerment through support, b) interference of parent in adulthood, c) connection to inner child and need to re-parent, d) low self-esteem and insecurity, e) anger and resentment, f) romantic relationship problems, and g) problems communicating. The results of this study provide insight into the issues that adult children of alcoholics need to address as part of their own recovery and suggest avenues of exploration for practitioners who work with high risk families.Peer reviewe

    Public debt sustainability: international perspectives/ edited by Barry W. Poulson, John Merrifield, and Steve H. Hanke.

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    Includes bibliographical references and index."This book examines the issue of debt sustainability from an international perspective, with reference to European countries, emerging nations, and the United States"--Part I: Rules-based fiscal policy in the United States. -- Organizing congress for budget reforms / Kurt Couchman -- Debt fatigue and the climacteric in U.S. economic growth / John Merrifield and Barry Poulson -- Part II: rules-based fiscal policy in Europe. -- Preparing for the next crisis: lessons from the successful Swedish fiscal framework / Fredrik N. G. Andersson and Lars Jonung -- The Swiss federal debt brake and its unbudgeted surpluses /Vera Z. Eichenauer and Jan-Egbert Sturm -- The German "debt brake": success factors and challenges -- Lars P. Feld and Wolf H. Reuter -Part III: rules-based fiscal and monetary policy in emerging nations. -- A money doctor's reflections on currency reforms and hard budget constraints /Steve H. Hanke -- Fiscal rules and public debt: an emerging market perspective / Pablo E. Guidott -- Populist economic thought: the legacy of Juan Domingo Perón -- Carlos Newland and Emilio Ocampo -- Part IV: is non-conventional monetary policy supporting or undermining fiscal stabilization policy? -- Monetary policy and the worsening U.S. debt crisis / Norbert j. Michel -- The Federal Reserve and the debt crises / Thomas r. Saving -- The high costs of fiscal and monetary anomie: Argentina since 1945 / Emilio Ocampo -- Part V: The ultimate challenge for fiscal sustainability entitlement reform. -- The failure to establish effective rules for financing U.S. federal entitlement programs / Charles Paul Blahous -- Fiscal rules for Social Security and Medicare: would accrual accounting help? / James C. Capretta.1 online resource (unpaged)
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