43,827 research outputs found
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
Intracellular single-chain variable fragments directed to the Src homology 2 domains of Syk partially inhibit Fc epsilon RI signaling in the RBL-2H3 cell line
No full textIntracellular expression of Ab fragments has been efficiently used to inactivate therapeutic targets, oncogene products, and to induce viral resistance in plants. Ab fragments expressed in the appropriate cell compartment may also help to elucidate the functions of a protein of interest. We report in this study the successful targeting of the protein tyrosine kinase Syk in the RBL-2H3 rat basophilic leukemia cell line. We isolated from a phage display library human single-chain variable fragments (scFv) directed against the portion of Syk containing the Src homology 2 domains and the linker region that separates them. Among them, two scFv named G4G11 and G4E4 exhibited the best binding to Syk in vivo in a yeast two-hybrid selection system. Stable transfectants of RBL-2H3 cells expressing cytosolic G4G11 and G4E4 were established. Immunoprecipitation experiments showed that intracellular G4G11 and G4E4 bind to Syk, but do not inhibit the activation of Syk following FcepsilonRI aggregation, suggesting that the scFv do not affect the recruitment of Syk to the receptor. Nevertheless, FcepsilonRI-mediated calcium mobilization and the release of inflammatory mediators are inhibited, and are consistent with a defect in Bruton's tyrosine kinase and phospholipase C-gamma2 tyrosine phosphorylation and activation. Interestingly, FcepsilonRI-induced mitogen-activated protein kinase phosphorylation is not altered, suggesting that intracellular G4G11 and G4E4 do not prevent the coupling of Syk to the Ras pathway, but they selectively inhibit the pathway involving phospholipase C-gamma2 activation
Prompt charm production in pp collisions at √<span style="text-decoration:overline">s</span>=7 TeV
No full textCharm production at the LHC in pp collisions at s√=7 TeV is studied with the LHCb detector. The decays D0→K−π+, D+→K−π+π+, D⁎+→D0(K−π+)π+, D+s→ϕ(K−K+)π+, Λ+c→pK−π+, and their charge conjugates are analysed in a data set corresponding to an integrated luminosity of 15 nb−1. Differential cross-sections dσ/dpT are measured for prompt production of the five charmed hadron species in bins of transverse momentum and rapidity in the region 0<pT<8 GeV/c and 2.0<y<4.5. Theoretical predictions are compared to the measured differential cross-sections. The integrated cross-sections of the charm hadrons are computed in the above pT-y range, and their ratios are reported. A combination of the five integrated cross-section measurements gives
σ(cc¯)pT<8 GeV/c,2.0<y<4.5=1419±12(stat)±116(syst)±65(frag) μb,
where the uncertainties are statistical, systematic, and due to the fragmentation functions
Erratum to: Effects of nutraceuticals on quality of life and sexual function of perimenopausal women (Journal of Endocrinological Investigation, (2017), 40, 1, (27-32), 10.1007/s40618-016-0500-2)
No full textUnfortunately, one of the co-author first name was wrongly published in the original version. The complete correct name of the co-author is given below. A. M. C. Rapisarda. The original version of this article is also updated
Measurement of the CP-violating phase \phi s in Bs->J/\psi\pi+\pi- decays
No full textMeasurement of the mixing-induced CP-violating phase phi_s in Bs decays is of prime importance in probing new physics. Here 7421 +/- 105 signal events from the dominantly CP-odd final state J/\psi pi+ pi- are selected in 1/fb of pp collision data collected at sqrt{s} = 7 TeV with the LHCb detector. A time-dependent fit to the data yields a value of phi_s=-0.019^{+0.173+0.004}_{-0.174-0.003} rad, consistent with the Standard Model expectation. No evidence of direct CP violation is found
Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′
No full textFirst evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)
Measurement of the inclusive φ cross-section in pp collisions at √s=7 TeV
No full textThe cross-section for inclusive φ meson production in pp collisions at a centre-of-mass energy of √s = 7 TeV has been measured with the LHCb detector at the Large Hadron Collider. The differential cross-section is measured as a function of the φ transverse momentum pT and rapidity y in the region 0.6< pT <5.0 GeV/c and 2.44< y <4.06. The cross-section for inclusive φ production in this kinematic range is σ(pp→φX)=1758±19(stat) +43−14(syst)±182(scale) μb, where the first systematic uncertainty depends on the pT and y region and the second is related to the overall scale. Predictions based on the Pythia 6.4 generator underestimate the cross-section
C3H7NO2S effect on concrete steel-rebar corrosion in 0.5 M H2SO4 simulating industrial/microbial environment
No full textThis paper investigates C3H7NO2S (Cysteine) effect on the inhibition of reinforcing steel corrosion in concrete immersed in 0.5 M H2SO4, for simulating industrial/microbial environment. Different C3H7NO2S concentrations were admixed, in duplicates, in steel-reinforced concrete samples that were partially immersed in the acidic sulphate environment. Electrochemical monitoring techniques of open circuit potential, as per ASTM C876-91 R99, and corrosion rate, by linear polarization resistance, were then employed for studying anticorrosion effect in steel-reinforced concrete samples by the organic hydrocarbon admixture. Analyses of electrochemical test-data followed ASTM G16-95 R04 prescriptions including probability distribution modeling with significant testing by Kolmogorov-Smirnov and student's t-tests statistics. Results established that all datasets of corrosion potential distributed like the Normal, the Gumbel and the Weibull distributions but that only the Weibull model described all the corrosion rate datasets in the study, as per the Kolmogorov-Smirnov test-statistics. Results of the student's t-test showed that differences of corrosion test-data between duplicated samples with the same C3H7NO2S concentrations were not statistically significant. These results indicated that 0.06878 M C3H7NO2S exhibited optimal inhibition efficiency η = 90.52±1.29% on reinforcing steel corrosion in the concrete samples immersed in 0.5 M H2SO4, simulating industrial/microbial service-environment
A Robust Design for Cellular Vehicles of Gold Nanorods for Multimodal Imaging
No full textAuthors Dr. Marisa Benagiano and Prof. Mario Milco D’Elios were not included when this article was originally published. The corrected list of author of this manuscript is: F. Ratto,* S. Centi, C. Avigo, C. Borri, F. Tatini, L. Cavigli, C. Kusmic, B. Lelli, S. Lai, M. Benagiano, M. M. D’Elios, S. Colagrande, F. Faita, L. Menichetti, and R. Pini The affiliation for Dr. Benagiano and Prof. D’Elios is: Department of Experimental and Clinical Medicine University of Florence, Largo Brambilla 3, 50134 Florence, (FI), Italy Ref. [82] was not included in the originally published version of this article. It should be added to the second paragraph on page 7179, which then reads as follows: “More recently, the notion to exploit the natural tropism of cells, such as tumor-associated macrophages,[35–39] T cells,[40,82] mesenchymal stem cells,[41–43] and neural stem cells,[44,45] has begun to emerge as a radical alternative.” Ref. [82] is: G. Baldi, C. Ravagli, M. Comes Franchini, M. M. D’Elios, M. Benagiano, M. Bitossi (Colorobbia Italia S.p.A.) WO 104664, 2015. The Acknowledgements should be corrected to read as follows: “This work was in part supported by the Projects of Tuscan Region “NANOTREAT” and “SYNERGY” and by the ERANET+ Project of Tuscan Region and European Community “LUS BUBBLE”. The authors wish to thank Dr. Daniele Panetta for his expertise in X-ray micro imaging and Dr. Giovanni Baldi of CERICOL Research Center of Colorobbia Group for his expertise and knowledge on cellular nano-engineering.” The authors apologize for any inconvenience or misunderstanding that these errors may have caused. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinhei
Ridica merida Opitz 2019, nov.sp.
No full textRidica meridaOPITZnov.sp. (Figs 49, 104, 307) Holotype: ♀. Type locality: VENEZUELA, 20 km SW El Vig’a Merida, XII-10-1969, el. 50 m, L. Wood (FSCA). D i a g n o s i s: The members of this species are conveniently distinguished from those of its congener by the shape of the 8 th antennomere and by the sculpture on the elytral disc. In Ridica merida the 8 th antennomere is quadrate and the elytral disc shows 4 longitudinal carinae, whereas in specimens of R. achira the 8 th antennomere is oblong and the elytral disc is devoid of longitudinal carinae. D e s c r i p t i o n: Size: Length 9.0 mm; width 2.2 mm. Form: As in Fig. 307. Color: Cranium bicolored, mostly black, upper frons with central linear testaceous line; prothorax bicolored, pronotal sides testaceous, remainder of prothorax black; antenna black, last antennomeres not seen; pterothorax, legs, and abdomen black; elytra bicolorous, sutural margins narrowly black in basal 1/2, disc testaceous. Head: Antenna (Fig. 49) capitate, funicular antennomeres transverse, capitular antennomeres 8 and 9 broad-oblong, capitular antennomere 10 missing; eyes large, finely facetted, eye as wide as frons (EW/FW 29/29). Thorax: Pronotum (Fig. 104) quadrate, disc coarsely punctate (PW/PL 75/75); pronotal tubercle broad, disc concave paralaterally near pronotal collar, discal and lateral trichobothria well developed; elytral asetiferous punctures small, profusely distributed (EL/EW 430/75); anterior margin of protibia with 7 spines. Abdomen: Pygidium transverse/scutiform. N a t u r a l H i s t o r y: The available specimen was collected in December, at 50 m. D i s t r i b u t i o n: This species is known from Venezuela. E t y m o l o g y: The trivial name, merida, is a noun in apposition and refers to the type locality.Published as part of Opitz, Weston, 2019, Descriptions of new genera and new species of Western Hemisphere checkered beetles (Coleoptera, Cleroidea, Cleridae), pp. 959-1076 in Linzer biologische Beiträge 51 (2) on pages 989-990, DOI: 10.5281/zenodo.374674
- …
