498 research outputs found
L’assistance d’État gérée par l’assurance maladie (CMU/AME)
No full textRT6 Working Paper 2021Implementation of Universal Health Coverage (CMU) / State Medical Aid (AME) in 2000 is part of a historic tension between assistance and insurance. Far from finalizing the process of universalizing social protection, the CMU / AME constitutes a state assistance mechanism. The increase in the cost of the latter, observed and studied in a primary health insurance fund from 2004 to 2008, is embedded in a new managerial organization of physical reception which governs the classification and downgrading of users and agents. This State assistance system, linked to the reconfiguration of reception, generates, among reception agents, uses of discretionary power - ranging from benevolence to punishment - in their interrelations at the counter with the most frequent users precarious. The exercise of discretionary power originates in the new governance of health insurance which calls for the managerial rationalization of physical reception, the "control of expenditure" and the "fight against fraud". In a configuration where health insurance has been invested with a state function, the "assisted" depends strongly on the moral judgment of the agent, who by the exercise of pastoral power (Foucault, 2004) makes the doubly dependent user.La mise en oeuvre de la Couverture maladie universelle (CMU)/ Aide médicale État (AME) en 2000 s'inscrit dans une tension historique entre assistance et assurance. Loin de finaliser le processus d'universalisation de la protection sociale, la CMU/AME constitue un dispositif d'assistance d'État. La montée en charge de ce dernier, observé et étudié dans une Caisse primaire d'assurance maladie de 2004 à 2008, s'encastre dans une nouvelle organisation managériale de l'accueil physique qui préside au classement-déclassement des usagers et des agents. Ce dispositif d'assistance d'État, articulé à la reconfiguration de l'accueil engendre, chez les agents d'accueil, des usages du pouvoir discrétionnaire-allant de la bienveillance à la punition-dans leurs interrelations au guichet avec les usagers les plus précaires. L'exercice du pouvoir discrétionnaire s'origine dans la nouvelle gouvernance de l'assurance maladie qui convoque la rationalisation managériale de l'accueil physique, la « maitrise des dépenses » et la « lutte contre les fraudes ». Dans une configuration où l'assurance maladie a été investie d'une fonction d'État, l'« assisté » dépend fortement du jugement moral de l'agent, qui par l'exercice du pouvoir pastoral (Foucault, 2004) rend l'usager doublement tributaire
L’assistance d’État gérée par l’assurance maladie (CMU/AME)
No full textRT6 Working Paper 2021Implementation of Universal Health Coverage (CMU) / State Medical Aid (AME) in 2000 is part of a historic tension between assistance and insurance. Far from finalizing the process of universalizing social protection, the CMU / AME constitutes a state assistance mechanism. The increase in the cost of the latter, observed and studied in a primary health insurance fund from 2004 to 2008, is embedded in a new managerial organization of physical reception which governs the classification and downgrading of users and agents. This State assistance system, linked to the reconfiguration of reception, generates, among reception agents, uses of discretionary power - ranging from benevolence to punishment - in their interrelations at the counter with the most frequent users precarious. The exercise of discretionary power originates in the new governance of health insurance which calls for the managerial rationalization of physical reception, the "control of expenditure" and the "fight against fraud". In a configuration where health insurance has been invested with a state function, the "assisted" depends strongly on the moral judgment of the agent, who by the exercise of pastoral power (Foucault, 2004) makes the doubly dependent user.La mise en oeuvre de la Couverture maladie universelle (CMU)/ Aide médicale État (AME) en 2000 s'inscrit dans une tension historique entre assistance et assurance. Loin de finaliser le processus d'universalisation de la protection sociale, la CMU/AME constitue un dispositif d'assistance d'État. La montée en charge de ce dernier, observé et étudié dans une Caisse primaire d'assurance maladie de 2004 à 2008, s'encastre dans une nouvelle organisation managériale de l'accueil physique qui préside au classement-déclassement des usagers et des agents. Ce dispositif d'assistance d'État, articulé à la reconfiguration de l'accueil engendre, chez les agents d'accueil, des usages du pouvoir discrétionnaire-allant de la bienveillance à la punition-dans leurs interrelations au guichet avec les usagers les plus précaires. L'exercice du pouvoir discrétionnaire s'origine dans la nouvelle gouvernance de l'assurance maladie qui convoque la rationalisation managériale de l'accueil physique, la « maitrise des dépenses » et la « lutte contre les fraudes ». Dans une configuration où l'assurance maladie a été investie d'une fonction d'État, l'« assisté » dépend fortement du jugement moral de l'agent, qui par l'exercice du pouvoir pastoral (Foucault, 2004) rend l'usager doublement tributaire
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
The GeT-TRiX facility: automated processing of expression microarrays - from samples to data analysis reports
No full textInternational audienc
CCA: An R package to extend canonical correlation analysis
No full textCanonical correlations analysis (CCA) is an exploratory statistical method to highlight correlations between two datasets acquired on the same experimental units. The cancor () function in R (R Development Core Team 2007) performs the core of computations but further work was required to provide the user with additional tools to facilitate the interpretation of the results. We implemented an R package, CCA, freely available from the Comprehensive R Archive Network (CRAN, http://CRAN.R-project.org/), to develop numerical and graphical outputs and to enable the user to handle missing values. The CCA package also includes a regularized version of CCA to deal with datasets with more variables than units. Illustrations are given through the analysis of a dataset coming from a nutrigenomic study in the mouse
The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming
No full textConversion of promoter-proximally paused RNA polymerase II (RNAPII) into elongating polymerase by the positive transcription elongation factor b (P-TEFb) is a central regulatory step of mRNA synthesis. The activity of P-TEFb is controlled mainly by the 7SK small nuclear ribonucleoprotein (snRNP), which sequesters active P-TEFb into inactive 7SK/P-TEFb snRNP. Here we demonstrate that under normal culture conditions, the lack of 7SK snRNP has only minor impacts on global RNAPII transcription without detectable consequences on cell proliferation. However, upon ultraviolet (UV)-light-induced DNA damage, cells lacking 7SK have a defective transcriptional response and reduced viability. Both UV-induced release of "lesion-scanning" polymerases and activation of key early-responsive genes are compromised in the absence of 7SK. Proper induction of 7SK-dependent UV-responsive genes requires P-TEFb activity directly mobilized from the nucleoplasmic 7SK/P-TEFb snRNP. Our data demonstrate that the primary function of the 7SK/P-TEFb snRNP is to orchestrate the proper transcriptional response to stress
Comparing plasmonic electrodes prepared by electron-beam lithography and electrochemical reduction of an Au (iii) salt: application in active plasmonic devices
No full textInternational audienceThis work describes two different methods for obtaining electrodes covered with gold nanoparticles: electron-beam lithography and electroreduction of an Au (III) salt by chronoamperometry. Localized surface plasmon resonances of these different electrodes have been compared. In a second step, these plasmonic AuNP electrodes were covered with an ultrathin organic film of bisthienylbenzene which displays a reversible voltage-dependent switch between conducting and insulating states. The effect of this conductance switch on the plasmonic properties of the AuNPs has been studied
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