961 research outputs found
Optic nerve gliomas: correlation between clinical and histological presentation and labelling indexes by PCNA and MIB-1 (Ki67) antibodies.
CO measurements from the ACE-FTS satellite instrument: data analysis and validation using ground-based, airborne and spaceborne observations
The Atmospheric Chemistry Experiment (ACE) mission was launched in August 2003 to sound the atmosphere by solar occultation. Carbon monoxide (CO), a good tracer of pollution plumes and atmospheric dynamics, is one of the key species provided by the primary instrument, the ACE-Fourier Transform Spectrometer (ACE-FTS). This instrument performs measurements in both the CO 1-0 and 2-0 ro-vibrational bands, from which vertically resolved CO concentration profiles are retrieved, from the mid-troposphere to the thermosphere. This paper presents an updated description of the ACE-FTS version 2.2 CO data product, along with a comprehensive validation of these profiles using available observations (February 2004 to December 2006). We have compared the CO partial columns with ground-based measurements using Fourier transform infrared spectroscopy and millimeter wave radiometry, and the volume mixing ratio profiles with airborne (both high-altitude balloon flight and airplane) observations. CO satellite observations provided by nadir-looking instruments (MOPITT and TES) as well as limb-viewing remote sensors (MIPAS, SMR and MLS) were also compared with the ACE-FTS CO products. We show that the ACE-FTS measurements provide CO profiles with small retrieval errors (better than 5% from the upper troposphere to 40 km, and better than 10% above). These observations agree well with the correlative measurements, considering the rather loose coincidence criteria in some cases. Based on the validation exercise we assess the following uncertainties to the ACE-FTS measurement data: better than 15% in the upper troposphere (8-12 km), than 30% in the lower stratosphere (12-30 km), and than 25% from 30 to 100 km. © Author(s) 2008.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
2000 Sub-Librarians Meeting: Ace Atkins and M.C. Beaton
The Sub-Librarians planned and advertised a program with renowned science fiction and fantasy author Philip Jose Farmer. George Scheetz was instrumental in making that introduction. However, due to ill health, Farmer was unable to travel and had to cancel close to the program date.
However, on very short notice, Ace Atkins agreed to come to Chicago and speak to the group. Atkins had spoken to a very appreciative group of Sub-Librarians the previous year in New Orleans, and he gave another stellar performance in Chicago. He talked about his new book, Leaving\u27 Trunk Blues, which is another Nick Travers mystery, this one set in Chicago, from St. Martin\u27s Press.
St. Martin\u27s also stepped up and offered to have author M.C. Beaton join Ace as a speaker. M.C. Beaton is a pseudonym of Marion Chesney, who may be best known as the author of romance novels set during the English Regency. Her first detective story as M.C. Beaton came out for St. Martin\u27s in 1985. She has two series-one set in Scotland with Hamish Macbeth and one set in the Cotswolds with Agatha Raisin.
St. Martin\u27s generously provided copies of both authors\u27 books for signing after the program.
Marsha Pollak chaired the program, welcomed the audience, explained the change in speakers, called for toasts and introduced the authors
COMMISSIONING ACTIVITIES FOR THE ACE MISSION
Author Institution: Department of Chemistry, University of WaterlooThe SCISAT-1 satellite for the Atmospheric Chemistry Experiment (ACE) mission was launched on August 12, 2003. The main goal of the mission is to investigate the chemical and dynamical processes that control the distribution of ozone in the stratosphere and upper troposphere. The ACE instruments record spectra of Earth's atmosphere primarily using the solar occultation method. Commissioning activities and on-orbit data from the high resolution infrared Fourier transform spectrometer (ACE-FTS), the UV-visible-NIR MAESTRO spectrometer and the ACE solar imagers will be explained with emphasis on the ACE-FTS
THE ACE SATELLITE SOLAR SPECTRUM
Author Institution: Institut fur Meteorologie und Klimaforschung, Forschungszentrum Karlsruhe, Postfach 3640, D-76021 Karlsruhe, Germany; Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1; Department of Physics, University of Toronto, Toronto, Ontario, Canada M5S 1A7; Department of Chemistry, University of York, Heslington, York, YO10 5DD, UKThe Canadian ACE (Atmospheric Chemistry Experiment) mission has a high resolution (0.02 cm) Fourier transform spectrometer (FTS) in low earth orbit. ACE was launched by NASA in August 2003 and the FTS continues to operate without any degradation in performance. The primary ACE mission goal is the study ozone chemistry in the stratosphere although it is making a wide range of other measurements, for example, of organic molecules in the troposphere. In the normal operating mode, the ACE-FTS measures a sequence of atmospheric absorption spectra during sunrise and sunset ("solar occultation''). As part of the measurement sequence about 16 high sun exoatmospheric spectra are recorded for each occultation to serve as reference spectra. ACE has now measured about 18000 occultations and we have co-added 224782 pure solar spectra to produce the ACE solar atlas in the 750--4400 cm spectral region. As compared to the previous ATMOS solar atlas, the ACE atlas generally has a higher signal-to-noise ratio but covers a smaller spectral range and contains only solar lines. The ACE atlas will be presented and compared with the ATMOS atlas
Identification of ACE inhibitory peptides from red alga Mazzaella japonica
Angiotensin I converting enzyme (ACE) inhibition is one of the key factors for cardiovascular disease, and inhibition of ACE activity is related to the prevention of high blood pressure. Until now, some ACE inhibitory peptides have been found in the protein hydrolysates of red algae, and most of them were derived from phycobiliproteins and rubisco. In this study, we modified the preparation method to evaluate the potential of ACE inhibitory activity from protein hydrolysate of red algaMazzaella japonicaexcept for phycobiliproteins and rubisco. As a result, we identified 11 peptides (YRD, VSEGLD, TIMPHPR, GGPAT, SSNDYPI, SRIYNVKSNG, VDAHY, CPYDWV, YGDPDHY, NLGN and DFGVPGHEP) in the hydrolysate by the reversed phase-HPLC and MALDI-TOF/MS/MS. Among them, YRD would be derived from phycoerythrin alpha-subunit. However, the others would be from other proteins encoded in chloroplast or nuclear genomes. This study revealed that not only phycobiliproteins and rubisco but also the other proteins in red algae have the potential for the source of ACE inhibitory peptide
Agent-Based Computational Economics: A Constructive Approach to Economic Theory
This chapter explores the potential advantages and disadvantages of Agent-based Computational Economics (ACE) for the study of economic systems. General points are concretely illustrated using an ACE model of a two-sector decentralized market economy. Six issues are highlighted: Constructive understanding of production, pricing, and trade processes; the essential primacy of survival; strategic rivalry and market power; behavioral uncertainty and learning; the role of conventions and organizations; and the complex interactions among structural attributes, behaviors, and institutional arrangements. Extensive annotated pointers to ACE surveys, research, course materials, and software can be accessed here: http://www.econ.iastate.edu/tesfatsi/ace.htmagent-based computational economics; Learning; network formation; decentralized market economy
Hungary's bankruptcy experience, 1992-93
Hungary adopted a tough new bankruptcy law in late 1991 that took effect on January 1, 1992. It required managers of firms with arrears over 90 days to any creditor to file for either reorganization or liquidation within eight days (the so-called"automatic trigger") and provided a rather sympathetic framework in which to do so. The result: since January 1992, more than 25,000 cases have been filed - far beyond lawmakers'expectations. Both positive and negative views about the law have been expressed, but details about how the process has actually worked have been scarce. The authors help fill this information gap by providing detailed data on a randomly selected stratified sample of actual cases filed in 1992-93, supplemented by information gained through interviews with judges, liquidations, and firms involved in bankruptcy. Their conclusions are as follows. First, the bankruptcy process appears to have had some degree of economic logic in 1992 and 1993. Better firms were more likely to enter and emerge"successfully"from reorganization, while worse firms were more likely either to fail in reorganization or to file directly for liquidation. Second, judicial reorganization need not be slow and costly. The first wave of reorganizations was handled surprisingly quickly, especially considering the sheer number of cases, the novelty of the process, and the shortage of trained judges. This quickness was possible largely because of the decentralized design of the process. Once the court approved a case, the court had little role. (Amendments added in 1993 may have made the process more bureaucratic and expensive). Third, in this sample, major delays occurred not in reorganization but in liquidation. Creditors will do almost anything to avoid filing for liquidation, and once firms enter liquidation they are still likely to be kept alive indefinitely. In the end, this lack of a viable creditor-led"exit"and debt collection mechanism harms firms by increasing the cost and reducing the flow of credit. Fourth, although the bankruptcy process displays some degree of economic logic, one should not assume that it operates as a similar law would in a market economy. In particular, a likely source of private gain in Hungary appears to be asset or other value diversion (or"value-stripping) before bankruptcy. Fifth, the main need is to strengthen the incentives of creditors to monitor the process closely and to improve their ability to do so.Banks&Banking Reform,International Terrorism&Counterterrorism,Strategic Debt Management,Small Scale Enterprise,Small and Medium Size Enterprises,Banks&Banking Reform,Strategic Debt Management,Legal Products,International Terrorism&Counterterrorism,Economic Theory&Research
In Silico Analysis of ACE Inhibitory Peptides from Chloroplast Proteins of Red Alga Grateloupia asiatica
Inhibition of angiotensin I-converting enzyme (ACE) is one of the key factors to repress high blood pressure. Although many studies have been reported that seaweed protein hydrolysates showed the ACE inhibitory activity, the comprehensive understanding of the relationship was still unclear. In this study, we employed chloroplast genome for in silico analysis and compared it with in vitro experiments. We first extracted water-soluble proteins (WSP) from red alga Grateloupia asiatica, which contained mainly PE, PC, APC, and Rbc, and prepared WSP hydrolysate by thermolysin, resulting that the hydrolysate showed ACE inhibitory activity. Then, we determined the complete chloroplast genome of G. asiatica (187,518 bp: 206 protein-coding genes, 29 tRNA, and 3 rRNA) and clarified the amino acid sequences of main WSP, i.e., phycobiliproteins and Rubisco, to perform in silico analysis. Consequently, 190 potential ACE inhibitory peptides existed in the main WSP sequences, and 21 peptides were obtained by in silico thermolysin digestion. By comparing in vitro and in silico analyses, in vitro ACE inhibitory activity was correlated to the IC50 value from in silico digestion. Therefore, in silico approach provides insight into the comprehensive understanding of the potential bioactive peptides from seaweed proteins
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