156,114 research outputs found
Binge Eating Disorder: A 5-Year Retrospective Study on Experimental Drugs
No full textMichelle N Levitan,1,2 Marcelo Papelbaum,2 Mauro G Carta,3 Jose C Appolinario,1 Antonio E Nardi1 1Psychiatry Institute/Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; 2Eating Disorders Department/Sheba Medical Center, Ramat Gan, Israel; 3Dipartimento di Scienze Mediche e Sanità Pubblica, Università Degli Studi di Cagliari, Cagliari, ItalyCorrespondence: Michelle N Levitan Email [email protected]: Binge eating disorder (BED) affects a significant rate of the general population causing a negative impact on their quality of life, weight, and self-esteem. Besides psychological treatments that compose the majority of the studies, pharmaceuticals have contributed to improve a host of clinical parameters, thus being an important component of the treatment. We opted to target the latest results by performing a review of the literature on the pharmacology for BED from the last 5 years. To achieve this goal, the terms: “binge eating disorder” and “treatment” were added to the PubMed database and the website clinicaltrials.gov. At least five drugs were either being tested or had already been recognized to improve BED symptoms – although only lisdexamfetamine is currently approved by the FDA to treat this condition. However, due to a better understanding of BED psychopathology in the last decade, it is notorious that improvement of eating-related symptoms is not the only desired target. Due to the significant comorbidity percentage (30%), weight loss is highly pursued, as well as the amelioration of clinical parameters which highlights the importance of having new agents combining both objectives.Keywords: binge eating disorder, treatment, pharmacological treatmen
Inverse scattering designs of dispersion-engineered single-mode planar waveguides
No full textWe use an inverse-scattering (IS) approach to design single-mode waveguides with controlled linear and higher-order dispersion. The technique is based on a numerical solution to the Gelfand-Levitan-Marchenko integral equation, for the inversion of rational reflection coefficients with arbitrarily large number of leaky poles. We show that common features of dispersion-engineered waveguides such as trenches, rings and oscillations in the refractive index profile come naturally from the IS algorithm without any a priori assumptions. Increasing the leaky-pole number increases the dispersion map granularity and allows design of waveguides with identical low order and differing higher order dispersion coefficients
Extending visual dominance over touch for input off the body
No full textHartcher O'Brien J, Levitan CA, Spence CJ. Extending visual dominance over touch for input off the body. Brain Research. 2011;1362:48-55
O. A. C. Review Volume XLVI Issue 5, February 1934
No full textThe focus of this issue is the preparation for College Royal and recognizing its tenth anniversary. This month's agricultural article is a report from the Dominion Parasite Laboratory on the biological control of pests. Other articles provide an account of the activities of a stage manager and the development of the field of home economics at Macdonald College in Quebec. Campus news addresses the success of the 1934 Conversazione, the commemorating of the sixtieth anniversary of the founding of O. A. C., the attendance at the Canadian Author Lecture, and the successful productions of "The Apple Cart" and "Iolanthe". The Macdonald Institute column comments on the Conversat and women's athletics activities in basketball and the rifle club. The Alumni Record supplies alumni updates.EditorialTen Years of the RoyalRamblings on the RoyalBlame it on the stage managerBiological control of insect pests in CanadaNot for girls onlyCollege lifeLiterary sectionO. A. C. sportsfolioAlumni recordMacdonald newsLetters to the editoradvertisin
O. A. C. Review Volume XXXVI Issue 12, August 1924
No full textThis slim summer issue contains the address given by the agricultural section of the British Association for the Advancement of Science, and a report on the visit of this association to the O. A. C. Other articles include instructions on increasing strawberry production and a biography of the author John Masefield. The editorial comments on Rhodes Scholars. The Alumni column provides an update of alumni activities. This issue does not contain a Macdonald column.JoyPresent-day problems in crop productionAfter the strawberry harvestJohn MasefieldVisit of the Agricultural Section of the British Association for the Advancement of ScienceEditorialCollege lifeAlumniadvertisin
New York State's Recycling Agricultural Plastics Project (RAPP): Hurdles and High Points
No full textThe Northeast United States supports a vibrant and diversified agriculture that generates lots of different types of plastic waste.
This presentation focuses on logistical decision points in developing a sustainable recycling infrastructure and viable recycling markets suited for agriculture and non-organic agricultural wastes.
The Recycling Agricultural Plastics Project (RAPP) is a Cornell University initiative working in collaboration with agricultural producers, and with organizations, agencies and businesses that support agriculture, environmental protection, regional economic development and recycling
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
The Thursday Murder Club: Launching a megabrand author - a publishing case study
No full textIn 2020, the Christmas book charts in the UK made headlines: Barack Obama’s eagerly awaited autobiography, The Promised Land, was beaten to the top spot by The Thursday Murder Club by Richard Osman, a debut cosy crime novel set in a retirement village. Not only did Osman’s book beat the former US president’s expected bestseller, it also broke records, becoming the fastest-selling debut crime novel of all time. Although Osman has a certain level of fame in the UK from his TV appearances on shows such as Pointless, his celebrity status does not entirely explain the novel’s huge sales. This article tracks the acquisition, publication, and promotion journey of The Thursday Murder Club in order to understand the industry and cultural context of its success and to interrogate the role of celebrity in the creation of author brands. The findings suggest that the unexpected scale of the success of the book owed to a number of factors, including in-depth editing by the novel’s agent, editor, and author to tighten up the plot, an extensive and strategic promotional campaign, the pandemic (which drove interest in the book’s genre and themes), and the quality of the writing. We find that the book’s success was accentuated by Osman’s celebrity status rather than being entirely reliant on it. This research adds to the growing scholarship on celebrity authorship by means of an in-depth case study and provides insight into the processes behind publishing a ‘celebrity’ book and launching a megabrand author
A Theme Analysis of Experiences Reported by Adult Children of Alcoholics in Online Support Forums
No full textGrowing up with an alcoholic parent can have a lasting effect on children and contribute to a variety of challenging outcomes in adulthood. This study identified the various experiences that adult children of alcoholics discuss with their peers in online support groups. Trained coders conducted a thematic analysis of 504 message board posts collected over a period of 60 days from three different online support groups to identify issues that children of alcoholics face in adulthood. Seven themes emerged from the analysis: a) empowerment through support, b) interference of parent in adulthood, c) connection to inner child and need to re-parent, d) low self-esteem and insecurity, e) anger and resentment, f) romantic relationship problems, and g) problems communicating. The results of this study provide insight into the issues that adult children of alcoholics need to address as part of their own recovery and suggest avenues of exploration for practitioners who work with high risk families.Peer reviewe
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