159,213 research outputs found
The Lancet Breast Cancer Commission
No full textThe Lancet Breast Cancer Commission—a diverse, multidisciplinary international group—are unanimous in our determination to improve the lives of all people who live with or are at risk of breast cancer. We came together in July, 2021, and are committed to raising the standard of breast cancer care to close the equity gap that exists between and within countries. Over a 2-year period, we brainstormed ideas, scoped the literature, obtained funding for dedicated pilot research that provided new data, and produced this Commission report to reduce the effects that breast cancer has on society
Department of Error: Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Study 2017 (The Lancet (2020) 395(10239) (1779–1801), (S0140673620301148), (10.1016/S0140-6736(20)30114-8))
No full textReiner RC Jr, Hay SI. Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Study 2017. Lancet 2020; 395: 1779–801—In this Article, the author byline has been amended to Local Burden of Disease Diarrhoea Collaborators. This correction has been made to the online version as of June 4, 2020, and the printed version is correct
Erratum: Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 (The Lancet (2018) 392(10159) (1736–1788)(S0140673618322037)(10.1016/S0140-6736(18)32203-7))
No full textGBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392: 1736–88—The bottom row in figure 7 was cut off. This correction has been made to the online version as of Nov 9, 2018, and has been made to the printed Article. © 2018 Elsevier Lt
Prevention and early detection of prostate cancer.
No full textProstate cancer is a common malignancy in men and the worldwide burden of this disease is rising. Lifestyle modifications such as smoking cessation, exercise, and weight control offer opportunities to reduce the risk of developing prostate cancer. Early detection of prostate cancer by prostate-specific antigen (PSA) screening is controversial, but changes in the PSA threshold, frequency of screening, and the use of other biomarkers have the potential to minimise the overdiagnosis associated with PSA screening. Several new biomarkers for individuals with raised PSA concentrations or those diagnosed with prostate cancer are likely to identify individuals who can be spared aggressive treatment. Several pharmacological agents such as 5α-reductase inhibitors and aspirin could prevent development of prostate cancer. In this Review, we discuss the present evidence and research questions regarding prevention, early detection of prostate cancer, and management of men either at high risk of prostate cancer or diagnosed with low-grade prostate cancer
Erratum: Eltrombopag for children with chronic immune thrombocytopenia (PETIT2): A randomised, multicentre, placebo-controlled trial (Lancet (2015) 386 (1649-1658)
No full textThe Lancet NCDI Poverty Commission: bridging a gap in universal health coverage for the poorest billion.
No full textFor the poorest of our world, non-communicable diseases
and injuries (NCDIs) account for more than a third of their
burden of disease; this burden includes almost
800000 deaths annually among those aged younger than
40 years, more than HIV, tuberculosis, and maternal
deaths combined.
• Despite already living in abject poverty, between
19 million and 50 million of the poorest billion spend a
catastrophic amount of money each year in direct
out-of-pocket costs on health care as a result of NCDIs.
• Progressive implementation of affordable, cost-effective,
and equitable NCDI interventions between 2020 and 2030
could save the lives of more than 4·6 million of the world’s
poorest, including 1·3 million who would otherwise die
before the age of 40 years.
• To avoid needless death and suffering, and to reduce the
risk of catastrophic health spending, essential NCDI
services must be financed through pooled, public
resources, either from increased domestic funding or
external funds.
• National governments should set and adjust priorities
based on the best available local data on NCDIs and the
specific needs of the worst off.
• International development assistance for health should
be augmented and targeted to ensure that the poorest
families affected by NCDIs are included in progress
towards universal health care
Lancet, Florence D.
No full textP. L. Lancet - husbandhttps://stars.library.ucf.edu/cfm-ch-memoranda-1935/1468/thumbnail.jp
The 2025 report of the Lancet Countdown on health and climate change: climate change action offers a lifeline
No full textDriven by human-caused greenhouse gas emissions, climate change is increasingly claiming lives and harming people's health worldwide. Mean annual temperatures exceeded 1·5°C above those of pre-industrial times for the first time in 2024. Despite ever more urgent calls to tackle climate change, greenhouse gas emissions rose to record levels that same year. Climate change is increasingly destabilising the planetary systems and environmental conditions on which human life depends.
Authored by 128 multidisciplinary experts worldwide, the 2025 report of the Lancet Countdown on health and climate change is the ninth—and most comprehensive—assessment of the links between climate change and health. The data in this report reveal that, as the health risks and impacts of climate change break concerning new records, progress is being reversed across key areas, further threatening health and survival. However, the evidence in this report also exposes important opportunities to accelerate action and prevent the most catastrophic impacts of climate change.We thank the Wellcome Trust for financial and strategic support, without which this research collaboration would not be possible. The Lancet Countdown's work was supported by an unrestricted grant from the Wellcome Trust (grant number 304972/Z/23/Z). We also thank the following individuals for their invaluable technical advice and input: Jessica Beagley, Santiago Begueria, Lucia Bevere, Max Callahan, Laura Clarke, Tara Daniel, Elise Digga, Robert Dubrow, Marcellin Guilbert, Jerome Jean Haegeli, Muhammad Hasan, Jennifer Israelsson, Samuel Julier, Mingyu Li, Vesna Milanovic, Mahnoor Saeed, Clare Scully, Daniel Tong, Sergio Vicente, Camille Voirin, and Peng Xian. Editorial note: The Lancet Group takes a neutral position with respect to territorial claims in published maps and institutional affiliations
International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025) : a human rights case for nephrology
No full textComment on:
Eliminating acute kidney injury by 2025: an achievable goal. [Lancet. 2015
Child death in high-income countries
No full textAlthough high income countries have made substantial progress towards reducing child mortality over recent decades, rates vary markedly between and within countries, and modifiable factors continue to be identified in many deaths. A series of three articles in The Lancet has described the epidemiology of child mortality and a standardised approach to child death reviews in high income countries. Patterns of child mortality at different ages are delineated into five broad categories: perinatal, congenital, acquired natural, external, and unexplained; while contributory factors are described across four broad domains: factors intrinsic to the child, the physical environment, the social environment, and service delivery. This commentary attempts to draw on the conclusions of these three articles and make practical recommendations on strategies in three key areas with perhaps the greatest potential to further reduce child mortality in high income countries: perinatal conditions, particularly preterm birth; acquired natural conditions, such as sepsis or acute respiratory problems; and external causes, including road traffic fatalities
- …
