1,196 research outputs found
Pen to Purpose: Cultivating Writing as a Brand of Professionalism with David Weill, MD
No full textJoin us online or in-person for a conversation with David Weill, MD, author of Exhale.
Exhale is the riveting memoir of a top transplant doctor who rode the emotional rollercoaster of saving and losing lives—until it was time to step back and reassess his own life.
Learn more about the author here.https://nsuworks.nova.edu/pen_to_purpose/1001/thumbnail.jp
Chapter 14: A New Holistic Focus on Quality of Life and Transformation
No full textIn this chapter, Dr. Cohen talks about his shift in focus away from reductionist research to a whole-life view of health and transformation. He explains that perspective goes back to experiences he had as a child and young adult in Italy, when he learned the benefits of being mindful about everything in his life. Next he tells the story of a turning point in 2009, when John Mendelsohn was interested in bringing author David Servan-Schreiber to MD Anderson to talk about his book, Anti-Cancer Way of Life. [NOTE: health info discussed, but Servan Schrieber is on record about it.] He tells the story of how Dr. Servan-Schrieber was able to inspire philanthropists to contribute several millions for a pilot Comprehensive Life Study in Stage 2 and 3 breast cancer patients. Dr. Cohen talks about how the design of the study and its transformational effect on patients.https://openworks.mdanderson.org/mchv_interviewchapters/1630/thumbnail.jp
Supplemental Data for A Phase II Study of Talazoparib Tosylate in Advanced Cancer Patients with Somatic and Germline (Not Breast or Ovarian Cancer) Alterations of BRCA1/2, Mutations/Deletions/Amplification in Other Homologous Recombination Repair Pathway Genes and PTEN or PTEN loss
No full textThe de-identified participant data and dataset generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
Custom code that was used in the generation or analysis of the datasets is available upon reasonable request.
Corresponding Author: Sarina Piha-Paul,Department of Investigational Cancer Therapeutics (A Phase I Clinical Trials Program), University of Texas MD Anderson Cancer Center, Houston, TX. Phone: (713)-563-1055, Fax:(713)-792-3535, [email protected]://openworks.mdanderson.org/ict/1000/thumbnail.jp
Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction
No full textAbnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance. We hypothesized that Nrf2 regulates steroid sensitivity via HDAC2 in response to inflammation in mouse lung. Furthermore, HDAC2 deficiency leads to steroid resistance in attenuating lung inflammatory response, which may be due to oxidant/antioxidant imbalance. Loss of antioxidant transcription factor Nrf2 resulted in decreased HDAC2 level in lung, and increased inflammatory lung response which was not reversed by steroid. Thus, steroid resistance or inability of steroids to control lung inflammatory response is dependent on Nrf2-HDAC2 axis. These findings have implications in steroid resistance, particularly during the conditions of oxidative stress when the lungs are more susceptible to inflammatory response, which is seen in patients with chronic obstructive pulmonary disease, asthma, rheumatoid arthritis, and inflammatory bowel disease
A Tribute to the Incomparable John S. Najarian, MD (1927-2020)
No full textIn this article, author Mary E. Knatterud, PhD, pays tribute to her incomparable longtime boss, transplant surgeon-scientist John S. Najarian, MD, who died at the age of 92 on August 31, 2020. The two worked together for several decades in the University of Minnesota Department of Surgery, which he chaired from July 1967 until February 1993. With deep affection and abiding respect, Knatterud describes his stellar academic background, internationally renowned career, and high-achieving yet genial style. She also showcases a cross-section of heartfelt comments (gathered by her, via email and/or phone, the sad week of his death) from colleagues in the workplace he built: Mary Jane Towle; Mary Dodds; Rainer W.G. Gruessner, MD; Barbara Elick, RN, BSN, MA; Henry Buchwald, MD, PhD; Catherine Statz, RN, MPH; and David A. Rothenberger, MD.Knatterud, Mary E. (2021). A Tribute to the Incomparable John S. Najarian, MD (1927-2020). Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/219611
Healing Insights from the Gospel of Mark: The Power of Social Connectedness
No full textDavid DeRose, MD, MPH, MAPMin, is a physician with specialties in both Internal Medicine and Preventive Medicine. His master’s degree in Public Health (MPH) featured an emphasis on Health Promotion and Health Education. In addition to his conventional training, DeRose has three decades of experience with lifestyle medicine and other natural therapies; he is a best-selling author and hosts a weekly syndicated radio broadcast. Dr. DeRose currently serves as pastor of the Fort Wayne First Seventh-day Adventist Church in Indiana and holds a master’s degree in Pastoral Ministry from Andrews University. He is married to Sonja Brandt DeRose, MD. They have three adult children
The Beatitudes: Prescription for a Health-Giving Spirituality
No full textDavid DeRose, MD, MPH, MAPMin, is a physician with specialties in both Internal Medicine and Preventive Medicine. His master’s degree in Public Health (MPH) featured an emphasis on Health Promotion and Health Education. In addition to his conventional training, DeRose has three decades of experience with lifestyle medicine and other natural therapies; he is a best-selling author and hosts a weekly syndicated radio broadcast. Dr. DeRose currently serves as pastor of the Fort Wayne First Seventh-day Adventist Church in Indiana and holds a master’s degree in Pastoral Ministry from Andrews University. He is married to Sonja Brandt DeRose, MD. They have three adult children
Healing Insights from the Gospel of Mark: Hope for the Hopeless
No full textDavid DeRose, MD, MPH, MAPMin, is a physician with specialties in both Internal Medicine and Preventive Medicine. His master’s degree in Public Health (MPH) featured an emphasis on Health Promotion and Health Education. In addition to his conventional training, DeRose has three decades of experience with lifestyle medicine and other natural therapies; he is a best-selling author and hosts a weekly syndicated radio broadcast. Dr. DeRose currently serves as pastor of the Fort Wayne First Seventh-day Adventist Church in Indiana and holds a master’s degree in Pastoral Ministry from Andrews University. He is married to Sonja Brandt DeRose, MD. They have three adult children
Healing through the Beatitudes: The Example of Hypertension
No full textDavid DeRose, MD, MPH, MAPMin, is a physician with specialties in both Internal Medicine and Preventive Medicine. His master’s degree in Public Health (MPH) featured an emphasis on Health Promotion and Health Education. In addition to his conventional training, DeRose has three decades of experience with lifestyle medicine and other natural therapies; he is a best-selling author and hosts a weekly syndicated radio broadcast. Dr. DeRose currently serves as pastor of the Fort Wayne First Seventh-day Adventist Church in Indiana and holds a master’s degree in Pastoral Ministry from Andrews University. He is married to Sonja Brandt DeRose, MD. They have three adult children
Measurement of the B0–B0 oscillation frequency Δmd with the decays B0→D−π+ and B0→ J/ψK∗0
No full textThe B
0
–B
0
oscillation frequency Δmd is measured by the LHCb experiment using a dataset corresponding
to an integrated luminosity of 1.0 fb−1
of proton–proton collisions at √
s = 7 TeV, and is found to be
Δmd
=0.5156±0.0051 (stat.)±0.0033 (syst.) ps−1
. The measurement is based on results from analyses
of the decays B
0
→ D
−π
+ (D
−
→ K
+π
−π
−) and B
0
→ J/ψK
∗0
(J/ψ →μ
+μ
−,K
∗0
→ K
+π
−) and
their charge conjugated modes
- …
