174 research outputs found
PESAN DAKWAH DALAM PAGELARAN WAYANG WONG LAKON “DURGA RUWAT”
No full textBudaya Jawa dewasa ini dipandang sebelah mata di beberapa kalangan, entah hal tersebut disebut kuno atau sudah ketinggalan zaman. Namun yang perlu diketahui, ajaran Jawa memiliki nilai dakwah yang luar biasa. Penelitian ini berfokus pada isi pesan dakwah pementasan wayang wong yang mengambil tema ruwatan sudamala, dikemas dalam bentuk pegelaran, dengan lakon “Durga Ruwat”, yang dipentaskan di Lotus Garden, Desa Ketanon, Kecamatan Kedungwaru Kabupaten Tulungagung. Metode deskriptif kualitatif merupakan metode yang digunakan dalam peneltian tersebut, yang terfokus pada pesan dakwah yang tersirat didalam pegelaran tersebut. Berdasarkan hasil yang didapat, ajaran Islam dan Jawa memiliki kesinambungan atau kesamaan yang tidak jauh berbeda. Jauh sebelum agama masuk, masyarakat Jawa sudah mengenal ajaran Ketuhanan, yang dikenal dengan ajaran Sangkan Paraning Dumadi. Agama Islam masuk bertujuan untuk menyempurnakan ajaran Jawa, kemudian pendakwah pada saat itu melakukan akulturasi budaya, yaitu memadukan dakwah Islam, menggunakan media pewayangan. Cerita wayang pada saat itu sudah mengalami banyak perubahan, serta sudah disisipkan pesan dakwah Islam, ajaran pokok yang disisipkan yaitu, Akidah, Syariah, dan Akhlak
Telaah atas Karya Tafsir di Indonesia: Studi atas Tafsir al-Bayan Karya Tm. Hasbi al-Siddiqi
No full textThis article discusses the characteristic of TM Hasbi as-Siddiqi’s Tafsir al-Bayan, its methodology and influence to the society. Indonesian Muslims’ reception toward this tafsir is also discussed. This article suggests that the the methodology of thre Quranic interpretation utilized in tafisr al-Bayan is analytical method or tahlili. This tafsir also puts emphasis on Islamic jurisprudence (fiqh), partly because the author of the Tafsir is reknowned as a professor in Islamic Law
Formation of Bayan-Aul District of Middle Juz
No full textThe article is devoted to the issue en the first third of the XIX century of the Bayan-Aul district formation on the territory of Middle Juz, which consisted of Kazakh tribal associations of the Central and North-East Kazakhstan.On the basis of archival materials the author analyzes the events related to this historical process
Telaah Atas Karya Tafsir Di Indonesia: Studi Atas Tafsir Al-Bayan Karya Tm. Hasbi Al-Siddiqi
No full textThis article discusses the characteristic of TM Hasbi as-Siddiqi's Tafsir al-Bayan, its methodology and influence to the society. Indonesian Muslims' reception toward this tafsir is also discussed. This article suggests that the the methodology of thre Quranic interpretation utilized in tafisr al-Bayan is analytical method or tahlili. This tafsir also puts emphasis on Islamic jurisprudence (fiqh), partly because the author of the Tafsir is reknowned as a professor in Islamic Law
In Vitro Evaluation of Smart Pellets as Intelligent Drug Delivery Systems
No full textIn Vitro Evaluation of Smart Pellets as Intelligent Drug Delivery Systems
Mohammad F. Bayan, Balakumar Chandrasekaran, Rahaf M. Allan and Weaam A. Khalaf
Faculty of Pharmacy, Philadelphia University, P.O. Box 1, Amman 19392, Jordan
Email: [email protected]
Introduction
The small intestine is where most conventional oral formulations are mostly absorbed. This restricts their usage in the treatment of several colon disorders since the medicine must act topically at the site of inflammation. This opened the door for the development of an intelligent colonic drug delivery system, which enhanced therapeutic effectiveness, decreased dosing frequency and potential side effects, and increased patient acceptance—particularly in situations where enemas or other topical preparations might not be sufficient to treat inflammation alone. This study's primary goal was to develop a smart medication delivery system based on pH-sensitive polymeric formulations made using a free-radical bulk polymerization technique. In the formulations, 5-amino salicylic acid was used as a model drug and Capmul MCM C8 was added to increase bioavailability. The in vitro swelling and release evaluation showed that the developed system may be able to delay drug release under conditions that mimic the stomach and small intestine while triggering it under conditions that mimic the colon, indicating its potential usefulness as a smart colonic drug delivery system.
Materials and Methods
Hydroxyethyl methacrylate (HEMA), Methacrylic acid (MAA), Dimethylaminoethyl methacrylate (DMAEMA), 5-amino salicylic acid, ethylene glycol dimethacrylate (EGDMA), disodium hydrogen phosphate dodecahydrate, azobisisobutyronitrile (AIBN), potassium chloride, sodium chloride, potassium dihydrogen phosphate, BRAND® stopcock grease, sodium dodecyl sulphate, and sodium hydroxide were purchased from Sigma-Aldrich. Capmul® MCM C8 was purchased from ABITEC. Hydrochloric acid (37%) was purchased from Biosolve Chimie.
Preparation of Intelligent Pellets: Nine pellet formulations based on HEMA, MAA, and/or DMAEMA monomers were prepared utilizing a free-radical thermal bulk polymerization technique [1]. The pellets were loaded with 5-amino salicylic acid and capmul MCM C8 as a dissolution enhancer and model drug, respectively. Pellets' Swelling Studies: The pellets' in vitro swelling behavior was examined in a biobase thermostatic shaking water bath SWB-A at 37 °C in buffers with equal ionic strengths at pH 1.2 and pH 7.4. The equilibrium swelling ratio and swelling behavior were examined as previously described by Bayan et al [2]. Pellets' Release Studies: The in vitro release of the model drug (5-amino salicylic acid) was examined using a modified Heelan and Corrigan method in a biobase thermostatic shaking water bath SWB-A working at 100 rounds per minute and 37 °C in buffers of equivalent ionic strength, at pH 1.2 and pH 7.4 [3]. After fitting the first 60% of the release data to the Korsmeyer-Peppas model, the release rate and mechanism of the medication were studied. The two-way analysis of variance test and Tukey's multiple comparison test (n = 3, p 0.05) were used to statistically examine all of the data. The graphics and statistical analyses were created using the GraphPad Prism software, version 9.4.0.
Results and Discussions
Figures 1-2 show the in vitro swelling profile and equilibrium swelling ratio of the pellets at each pH. When comparing the swelling profiles of HEMA-co-MAA pellets at pH 7.4 and pH 1.2, a significantly higher swelling was observed at pH 7.4. This may be attributed to the fact that these polymers' anionic pendant groups (MAA) were more ionized in the simulated intestinal fluid than in the simulated gastric fluid, resulting in stronger electrostatic interactions and increased swelling. At pH 1.2 compared to pH 7.4, the swelling profile for the HEMA-co-DMAEMA pellets was much higher. This may be related to the fact that these polymers' cationic pendant group (DMAEMA) were more ionized in the simulated gastric fluid than in the simulated intestinal fluid. Figures 3-4 display the in vitro release profiles of the produced pellets at each pH. In comparison to the HEMA-co-DMAEMA based pellets (F7-F9), the HEMA and HEMA-co-MAA based pellets (F1-F6) showed a greater ability to delay the release of the model drug at pH 1.2. When compared to the other formulations, the HEMA-co-MAA-based Pellets (F3-F6) showed a greater release rate at pH 7.4. With a cumulative release of almost 75% after 12 hours, F4 had the largest cumulative drug release at pH 7.4. After five hours at pH 1.2, this formulation attained a cumulative release of about 25%. An n value more than 0.5 and less than 1 was obtained for all pellets at pH 7.4 and for F7-F9 at pH 1.2, indicating an anomalous mechanism of drug release. This implies that diffusion and polymer swelling control the drug release in these formulations. At pH 1.2, F1–F6 pellets exhibited a n value lower than 0.5, indicating a Fickian diffusion mechanism.
Conclusions
The in vitro swelling and release investigations showed that F4 may be able to postpone the drug release while it is present in the stomach and small intestine, while triggering its release in the colon. This makes it promising to achieve a colonic-specific delivery for the potential treatment of colon-associated diseases, such as inflammatory bowel diseases. Further work is required to evaluate the in vivo behavior, biocompatibility, and safety of this system.
References
Bayan MF, Salem MS, Bayan RF. Development and In Vitro Evaluation of a Large-Intestinal Drug Delivery System. Research Journal of Pharmacy and Technology. 2022, 15(1):35-9.
Bayan MF, Marji SM, Salem MS, Begum MY, Chidambaram K, Chandrasekaran B. Development of Polymeric-Based Formulation as Potential Smart Colonic Drug Delivery System. Polymers. 2022, 14(17):3697.
Obaidat RM, Tashtoush BM, Bayan MF, T Al Bustami R, Alnaief M. Drying using supercritical fluid technology as a potential method for preparation of chitosan aerogel microparticles. Aaps Pharmscitech. 2015, 16(6):1235-44
Implementasi Sistem Informasi Administrasi Dalam Peningkatan Pelayanan Kesehatan Pada Puskesmas Bayan
No full textHealth center of Bayan is one of the main health center is location in the north of Lombok district. As the performance of systems running in patient care in the health center of Bayan is still not optimal for the data processing is still done use media bookkeeping. Many of the constraints experienced by the health center, including an error in the input, data storage, and can occur double patient files. So that data processing becomes ineffective and inefficient. There are several public and employee perception of the administration of health care information system in health center Bayan. This is the author's interest in conducting research on employee perceptions of the application of information systems administration in the improvement of health services in health center Bayan and in this case the author uses qualitative research methods in which a qualitative study that examines the participants with strategies that are interactive and flexible.
The qualitative research aimed at understanding social phenomena from the perspective of the participants. The results obtained from this study is an information system that is applied to the health center administration Bayan still using a manual system, which means keep using the computer but not connected to a data network local area network ( LAN) and does not use as a database server. From this study it can be concluded that the health care information system in health center Bayan already well underway although there are some deficiencies in the means of infrastructures and human resources
Pendidikan Karakter Dalam Membangun Moderasi Beragama Generasi Milenial di MA El-Bayan Majenang
No full textThis study aims to explore the implementation of character education in building religious moderation in MA El-Bayan Majenang. By conducting this research, it is hoped that it can provide an overview of the character education practices carried out at MA El-Bayan Majenang. The author also hopes that this research can provide useful information about the implementation of character education in building religious moderation in the millennial generation at MA El-Bayan Majenang. The research method used is descriptive method with a qualitative approach. Data were collected through observation, interviews and documentation studies. Research participants included teachers, students, and school staff involved in implementing character education at MA El-Bayan Majenang. The results of the research show that character education is an important effort in educating children to be able to make wise decisions and apply them in everyday life. Implementation of character education at MA El-Bayan Majenang through religious activities has succeeded in growing and increasing students' sense of religiosity. In this context, the millennial generation at MA El-Bayan Majenang shows a positive level of religious moderation. Based on the results of this study, it can be concluded that character education is an important component in building religious moderation in the millennial generation at MA El-Bayan Majenang. The practice of character education through religious activities can make a positive contribution in forming strong and moderate religious attitudes in students. These findings provide a better understanding of the importance of character education in the context of building religious moderation in the millennial generation
Artistic and Creative Figures of the Zhytomyr Bayan Trio “Harmonia”
No full textПредметом обговорення статті обрано відомий в Україні своєю концертною діяльністю та творчими здобутками колектив – житомирське тріо баяністів «Гармонія». Усвідомлюючи зміни, які зумовлені плинністю часу, авторка статті визначила аспект своєї наукової розвідки з огляду на вимоги сучасного музикознавства – висвітлити мистецько-творчі постаті житомирського тріо баяністів «Гармонія» у контексті особистісних і колективних здобутків мистецької творчості. У результаті вивчення та проведення аналізу різних історичних джерел дослідниця з’ясовує передумови появи нового культурно-історичного явища – житомирського тріо баяністів «Гармонія». Спираючись на інформацію першоджерел, науковиця у здійсненій розвідці розкриває практичний досвід кожного учасника житомирського тріо баяністів «Гармонія»: В.А. Губанова, В.Я. Омельчука, В.М. Богорядова, С.В. Петрука, Б.Ю. Талька, в інтегруючому напрямі педагогічної діяльності в Житомирському музичному фаховому коледжі імені В.С. Косенка. У процесі подання матеріалу статті дослідниця надає відомості про освіту баяністів; установлює початок педагогічної діяльності кожного учасника ансамблю в Житомирському музичному фаховому коледжі імені В.С. Косенка; означує сольні виконавські здобутки музикантів; зауважує широкий спектр колективного музикування баяністів у різних інструментальних ансамблях; відображує особистий внесок кожного із трьох баяністів першого складу
колективу у формування та наповнення концертного репертуару тріо баяністів «Гармонія» в аспекті перекладення музичних творів; виявляє високі результати педагогічної діяльності всіх членів колективу в контексті перемог їхніх студентів на всеукраїнських і міжнародних виконавських конкурсах; наголошує на важливості методичної діяльності баяністів із тріо «Гармонія»; зазначає просвітницьку діяльність членів колективу в аспекті концертної діяльності й організації та проведенні фестивалів баянно-акордеонного виконавства та народно-інструментального мистецтва; конкретизує дати змін виконавського складу колективу баяністів; висвітлює професійні здобутки житомирського тріо баяністів «Гармонія» на всеукраїнському та міжнародних конкурсах. Узагальнюючи наукову розвідку, авторка статті встановлює, що рушійною силою, які забезпечують безперервний процес існування житомирського тріо баяністів «Гармонія», є педагогічна діяльність учасників колективу – на зміну викладачу у виконавський склад ансамблю приходить його учень.The subject of the article is the Zhytomyr bayan trio “Harmonia”, an ensemble known in Ukraine for its concert activities and creative achievements. Aware of the changes caused by the passage of time, the author of the article defined an aspect of her scientific research in view of the requirements of modern musicology – to highlight the artistic and creative figures of the Zhytomyr bayan trio “Harmonia” in the context of personal and collective achievements of artistic creativity. By studying and analyzing various historical sources, the researcher uncovers the prerequisites for the emergence of a new cultural and historical phenomenon, the Zhytomyr trio of bayan players “Harmonia”. Based on the information from primary sources, the author reveals the practical experience of each member of the Zhytomyr bayan trio “Harmonia”: V.A. Hubanov, V.Ya. Omelchuk, V.M. Bohoriadov, S.V. Petruk, B.Yu. Talko in the integrating direction of pedagogical activity at the Zhytomyr Music Professional College named after V.S. Kosenko. In the course of presenting the material of the article, the researcher provides information about the education of bayan players; establishes the beginning of the pedagogical activity of each member of the ensemble at the Zhytomyr Music Professional College named after V.S. Kosenko; denotes the solo performing achievements of the musicians; emphasizes the wide range of collective musicianship of the bayan players in various instrumental ensembles; reflects the personal contribution of each of the three players of the first composition of the ensemble to the formation and expansion of the concert repertoire of the bayan trio “Harmonia” in terms of arrangements of musical works; reveals the high results of the pedagogical activity of all members of the ensemble in the context of their students’ victories at national and international performance competitions; emphasizes the importance of the methodological activity of players from the bayan trio “Harmonia”; highlights the educational activities of the ensemble members in terms of concert activities and the organization and holding of festivals of bayan and accordion performance and folk instrumental art; specifies the dates of changes of the performing members of the ensemble; highlights the professional achievements of the Zhytomyr bayan trio “Harmonia” at national and international competitions. Summarizing the scientific research, the author of the article establishes that the driving forces that ensure the continuous existence of the Zhytomyr bayan trio “Harmonia” are the pedagogical activities of the ensemble members: the student replaces the teacher in the ensemble’s performing lineup
MANIFESTASI INEN PAER: KETERHUBUNGAN PEREMPUAN DAN ALAM PADA MASYARAKAT ADAT BAYAN LOMBOKDITINJAU DARI WACANA EKOFEMINSIME KRITIS
No full textIn ecofeminism, the feminine qualities in the relationship between women and nature become a subject of debate between two views: accepting or rejecting their closeness. Acceptance is seen as essentialist for idealizing feminine traits, while rejection risks affirming patriarchal subjugation. Critical ecofeminism offers a middle path, this approach is an integrative project developed by the author, inspired by the intellectual spirit of Val Plumwood, who coined the term "critical ecological feminism" emphasizing critical self-affirmation to explore oppression systems without romanticizing the connection. This perspective forms the basis of the author’s reflection on the relationship between women and nature within the Indigenous Bayan community, analyzed through the lens of critical ecofeminism. The research employs a reflective-critical approach. The findings of this study reveal the following: 1) Nature and Earthothers within the Bayan Indigenous community are seen as active agents, regarded as subjects with their own souls, emotions, and unique characteristics. 2) The community respects diverse female experiences through the concepts of Gumi Nina, Gumi Bayan (Bayan Earth, Women's Earth). The term nina (women) reflects the unique characteristics of the Bayan Indigenous community, which upholds principles of non-domination, non-aggression, non-capitalization, non-ownership, and non-privatization in their leadership and environmental management systems. 3) The Bayan Indigenous community, through the concept of Inen Paer, does not view the closeness between women and nature as directly identical, as seen in the feminization of nature, such as the concept of Mother Earth, which implies that the mother is the Earth. Instead, Inen Paer means the Earth has a mother, namely Neneq Kaji Saq Kuase (the One Almighty God). 4) The domination of nature in the Bayan community, particularly against women, creates situated knowledge that becomes limited. Domination over nature by the state, through restrictions on traditional management spaces, has led to epistemic injustice. 5) The emancipatory politics advocated by the Bayan Indigenous community and their partners address not only the recognition of rights but also the fight against structural and epistemic injustices stemming from state domination.
Keywords: Bayan Indigenous community, Women, Nature, Critical Ecofeminis
MANIFESTASI EKUILIBRIUM DALAM KOSMOLOGI MASYARAKAT ADAT BAYAN DITINJAU DALAM PARADIGMA ECO-PHILOSOPHY
No full textThe phenomenon of environmental degradation is inseparable from every human activity that has consequences. This is further exacerbated by modern conservation and industrial logic, which view nature solely as a resource, thereby depriving nature of moral consideration. In this framework, humans become the center of value, where nature and other non-human entities only hold value when aligned with human benefits and measured by human interests. This contrasts with the understanding of indigenous communities, who are able to build an integrative relationship with nature and possess a romantic perspective in understanding their connection with it. This includes the principles of the Bayan indigenous community, whose livelihood depends on natural resources, leading to an intense social practice with nature. This has shaped the Bayan people's ethical view that nature is not merely understood as a resource asset but as part of a broader biotic community, including humans who are interconnected as part of that community. This intense relationship has existed for a long time and continues to be passed down, so that wetu telu as the philosophical basis of the Bayan people has become a social identity that not only teaches about relationships with God and fellow humans, but also encompasses human relationships with nature, which implicitly forms the ecological consciousness of the Bayan indigenous community. This study examines the cosmology of the Bayan indigenous community as a form of philosophy of life that is not only spiritual but also manifests itself in social practices and ecological management, particularly through the philosophy of wetu telu.
This type of research falls under the category of field research, which explores phenomena in their natural environment. This study employs a triangulation data collection method, comprising observation, interviews, and documentary analysis. Data findings are processed through data reduction, classification, presentation, interpretation, and conclusion-drawing. The data is then analyzed using Henryk Skolimowski's echophilosophy theory. In this theory, Skolimowski explains several key concepts such as Life Oriented and Values, spiritually alive, concerned with wisdom, environmentally and ecologically conscious, politically aware, socially aware, individually responsible, and tolerant of transphysical phenomena. These key concepts are used by the author to explain the relationship between humans and nature in the cosmology of the Bayan indigenous community.
The research findings explain, first, the Bayan cosmology, which is passed down through the wetu telu philosophy, becomes a lelakaq story that shapes human moral understanding as custodians, that is, preservers, protectors, or beautifiers. Second, the interpretation of nature as gumi nine or gumi mengina affirms the identity of women in traditional rituals. In Bayan customary practices, women are not only positioned as symbols of fertility or biological reproduction, but also as active participants and holders of authority in customary rituals. Third, Bayan cosmological praxis is reflected in daily activities such as land clearing, agriculture, and selametan rituals, which are based on customary norms such as the concepts of pemaliq and awiq-awiq. Fourth, with strong local characteristics, such as land, springs, forests,
and climate, Bayan cosmology has the potential to be a form of contextual bioregionalism philosophy rooted in the ecological experiences of the Bayan indigenous community. This is also pursued through the establishment of the Bayan Customary School as a space for internalizing customary values, and the community's participation in organizations to respond to ecological phenomena. This makes Bayan cosmology not only emphasize conce
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