95,064 research outputs found
K-theory for group C*-algebras
These notes are based on a lecture course given by the first author in the Sedano Winter School on K-theory held in Sedano, Spain, on January 22-27th of 2007. They aim at introducing K-theory of C*-algebras, equivariant K-homology and KK-theory in the context of the Baum-Connes conjectur
K maximum probability attack paths generation algorithm for target nodes in networked systems
As known, security system administrators need to be aware of the security risks and abnormal behaviors in a network system. Given the exploitation probability value of each vulnerability, the cumulative probability of an attack path from an attacker to a target node can be quantified and calculated, namely as the K maximum probability attack paths for a target node. It is proposed in this paper a design to compute the K maximum probability attack paths for a given set of target nodes, where available vulnerability sets for each node in the system are built and assigned to different access flags during the computation process of attack paths, aimed at reducing the computation costs. Experimental results show that the proposed design can improve the performance on the computation of the K maximum probability attack paths for a given set of target nodes, promising and more efficient than existing algorithms to generate the attack paths
Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling
The Tcf/Lef family of transcription factors mediates the Wnt/��-catenin pathway that is involved in a wide range of biological processes, including vertebrate embryogenesis and diverse pathogenesis. Post-translational modifications, including phosphorylation, sumoylation and acetylation, are known to be important for the regulation of Tcf/Lef proteins. However, the importance of ubiquitination and ubiquitin-mediated regulatory mechanisms for Tcf/Lef activity are still unclear. Here, we newly show that ubiquitin C-terminal hydrolase 37 (Uch37), a deubiquitinase, interacts with Tcf7 (formerly named Tcf1) to activate Wnt signalling. Biochemical analyses demonstrated that deubiquitinating activity of Uch37 is not involved in Tcf7 protein stability but is required for the association of Tcf7 to target gene promoter in both Xenopus embryo and human liver cancer cells. In vivo analyses further revealed that Uch37 functions as a positive regulator of the Wnt/��-catenin pathway downstream of ��-catenin stabilization that is required for the expression of ventrolateral mesoderm genes during Xenopus gastrulation. Our study provides a new mechanism for chromatin occupancy of Tcf7 and uncovers the physiological significance of Uch37 during early vertebrate development by regulating the Wnt/��-catenin pathway. ? 2017 The Author(s).113Ysciescopu
sj-docx-1-han-10.1177_15589447211068183 – Supplemental material for Repeat Irrigation and Debridement of Upper Extremity Infections: Do Repeat Cultures Change Antibiotic Treatment Regimens?
Supplemental material, sj-docx-1-han-10.1177_15589447211068183 for Repeat Irrigation and Debridement of Upper Extremity Infections: Do Repeat Cultures Change Antibiotic Treatment Regimens? by Bradley D. Wiekrykas, Jeffrey C. Wera, Gavin Rallis and Mark K. Solarz in HAND</p
Search for eta(c) decays into pi pi and K(K)over-bar
Using 58 million J/psi) events taken with the BESII detector, a search for eta(c) CP violating decays into pi pi and K (K) over bar has been performed. No clear 77, signal is observed, and upper limits for B(eta(c) -> pi pi) and B(eta(c) -> K (K) over bar) are given at the 90% confidence level, B(J/psi -> gamma eta(c)) center dot B(eta(c) -> pi(+)pi(-)) < 1.1 x 10(-5), B(J/psi -> gamma eta(c)) center dot B(eta(c) -> pi(0)pi(0)) < 0.71 x 10(-5), B(J/psi -> gamma(eta c)) center dot B(eta(c) -> K+K-) < 0.96 x 10(-5), and B(J/psi -> gamma eta(c)) center dot B(eta(c) (KSKS0)-K-0) < 0.53 x 10(-5).Physics, Particles & FieldsSCI(E)1ARTICLE2337-3414
Cognitive responses to favor request from social targets of different relationships in a Confucian society
Measurement of the ratio of branching fractions B(B0→K∗0γ )/B(B0s→φγ ) and the directCP asymmetry inB 0→K∗0γ
The ratio of branching fractions of the radiative B decays B0→K⁎0γ and B0s→ϕγ has been measured using an integrated luminosity of 1.0 fb−1 of pp collision data collected by the LHCb experiment at a centre-of-mass energy of s√=7TeV. The value obtained is
B(B0→K⁎0γ)B(B0s→ϕγ)=1.23±0.06(stat.)±0.04(syst.)±0.10(fs/fd),
where the first uncertainty is statistical, the second is the experimental systematic uncertainty and the third is associated with the ratio of fragmentation fractions fs/fd. Using the world average value for B(B0→K⁎0γ), the branching fraction B(B0s→ϕγ) is measured to be (3.5±0.4)×10−5.
The direct CP asymmetry in B0→K⁎0γ decays has also been measured with the same data and found to be
ACP(B0→K⁎0γ)=(0.8±1.7(stat.)±0.9(syst.))%.
Both measurements are the most precise to date and are in agreement with the previous experimental results and theoretical expectations
Infrared matrix isolation study of acetone and methanol in solid argon
The infrared absorption spectra of acetone and methanol mixtures have been investigated in a solid argon matrix at 9 K. A number of intramolecular complex bands were observed both in the acetone and methanol fundamental regions. From the concentration dependence of the infrared spectral pattern, acetone and methanol seemed to form a 1:1 binary complex. Noticeable red-shifts of the C=O stretching mode of acetone as well as the O-H stretching mode of methanol suggest that the two molecules are bound mainly through a H-bond between the carbonyl oxygen and the hydroxyl hydrogen atoms. A relatively weaker H-bonded interaction appeared also to act between the oxygen atom of methanol and a hydrogen atom of acetone. This view was found to be consistent with ab initio SCF, MP2, and DFT level computations. The most stable structure calculated was found to possess those two kinds of H-bonds, assuming a planar six-membered ring-like structure
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