410 research outputs found
Temperature : 27 February - 26 March 2010
No full textCatalogue of an exhibition held at SASA Gallery, Adelaide, 27 February-26 March 2010.Artists: Anton Hart & George Popperwell. Catalogue essay by external scholar: Dr Michael Tawa ; editor: Mary Knights
Molecular Fate Determinants in Embryonic and Adult Neural Stem Cells
No full textThe molecular signals specifying neuronal, glial or multipotent precursors in the developing and adult central nervous system (CNS) are largely unknown. Radial glial cells have recently been discovered as major precursor population generating neurons or glial cells in separate lineages in the developing CNS. Towards this aim to identify the key molecular determinants for neurogenic versus gliogenic fate in radial glial cells I used a novel method to selectively enrich neurogenic or non-neurogenic radial glia and compared their gene expression to adult subependymal zone (SEZ) precursors in vitro and in vivo. The expression profile of the transcription factors Olig2 and Pax6 were particularly intriguing. Olig2 was 67 fold higher in multipotent compared to neuronal or glial precursors, while Pax6 showed strongest expression in neuronal precursors. I therefore focused further on the functional analysis of Pax6 and Olig2 in neural stem cell in vitro and in vivo. Interference with Olig2 in neural stem cells in vitro revealed its role in self-renewal. In adult neural stem cells of the SEZ overexpression of Olig2 promoted oligodendrocyte formation. Pax6, in contrast, proved to be a very potent neurogenic determinant since neurogenesis is not only Pax6-dependent in neural stem cells in vitro, but also in adult neural stem cell in vivo.
Taken together, these results demonstrate a pathway combining transcription factors of dorsal and ventral regions that is activated in a specific lineage progression of adult neural stem cells in vitro and in vivo. Most importantly also in regard to therapeutic approaches, this work revealed the molecular mechanisms to direct adult neural stem cells towards a specific cell fate, neuronal or oligodendroglial
The later orchestral works of William Walton: a critical and analytical re-evaluation
No full textAlthough the British twentieth-century composer William Walton enJoys a continuing presence in the international canon, the body of scholarship that seriously engages with his life and work is small. The post-war music, which includes the Cello Concerto (1956), Second Symphony (1961), Variations on a Theme of Hindemith (1963), Improvisations on
an Impromptu of Benjamin Britten (1969), and the film score for Battle of Britain (1969), has been particularly underrepresented in critical and analytical writing. In this thesis, I give detailed analyses of these scores, alongside an investigation of the contemporary critical
climate and reception history of these works.
I argue that the series of significant lifestyle changes that Walton underwent in the years immediately following the Second World War - including exchanging the busy musical life of London and a series of affairs with high-profile figures for the 'dolce far niente' of an isolated Italian island and a stable marriage - are suggestive of a broad shift in the composer's social and cultural values with consequent changes in musical attitudes and compositional tendencies. Walton's later music is differentiated from the pre-war works by the presence of octatonic, twelve-note, hexatonic and other non-diatonic harmonic constructions in the foreground, and a change from teleological to network-based or rotational background structures. My analyses adopt a deliberately eclectic range of analytical strategies, combining aspects of set-class approaches alongside tools from the tonal tradition. This methodological pluralism reflects my argument that the vitality of these scores derives from a tension between modernist and traditional tendencies. I argue that
Walton appropriates a wide range of influences, including to some extent that of the European avant garde, in contradistinction to the assertion prominent in contemporary
reception literature that his music had stagnated into a single outmoded and rarefied style.
I conclude that although Walton's post-war music was indeed conservative in comparison to that of several of his younger contemporaries, his music engages, through opposition and assimilation, with many of the most characteristic trends of twentieth-century concert
music. Nevertheless, I argue that the temptation to label Walton as a 'modernist' should be avoided; his works should be judged on their own terms and not according to the
regressive--progressive axis prominent in much of the contemporary reception literature. These scores may not have been progressive, but they have a distinctive sound-world and an invigorating vitality that makes them exceptionally engaging both as works of art and
objects of study
Anton Martin Lublinský, that is Karl Dankwart : a few words about the painting Martin Středa as defender of Brno and its author
No full textThe painting Martin Středa as defender of Brno (Moravian Gallery in Brno) is the most monumental representation of the Jesuit Martin Středa / Stredonius (1587–1649), who won fame and the eternal gratitude of the citizens of Brno for his active participation in the defence of the city during the four-month siege by the Swedish army in 1645. Older authors saw Michael Willmann as the author of the painting. However, Milan Togner attributed this work to Anton Martin Lublinský (1636–1690). As it turns out today, the author of this monumental work was Karl Dankwart († 1704) – the author of numerous fresco decorations and oil paintings and court painter to the Polish king John III Sobieski. The authorship of this Silesian artist of Swedish origin is supported both by formal analogies and the provenance of the painting from the former Jesuit conventin Brno. Dankwart's painting of Father Středa was probably a part of the gallery of full-figure portraits of the founders and benefactors of the convent. We can assume that the picture was not the only work that Dankwart produced for the Jesuits of Brno
Biomedical enhancement and the pursuit of mastery and perfection: a critique of the views of Michael Sandel
No full textThis article is a comprehensive critical analysis of the objections of Michael Sandel to the possibilities of human enhancement as foreseen by recent developments in new (particularly genetic) biotechnologies. It is shown that enhancement has always been a feature of human development. The nature and possibilities of these new technologies are briefly discussed, followed by an explanation of Sandel’s views. In critical response to Sandel, the author raises three arguments that are discussed in detail, followed by a conclusion that contains wrap-up arguments. The three main arguments relate, first, to Sandel’s rejection of enhancement tout court, second to the (in)consistency of his argument about the ‘gifted’ nature of reality, and third to the problems raised by his idea that the striving for mastery is the main problem with enhancement. On the basis of an extensive analysis, the author finds Sandel’s position untenable. It is shown that Sandel espouses the ‘simple conservative argument’ (Buchanan). The author concludes that science and technology are not value free, and that the critical evaluation of enhancements cannot lead to an overall judgment, but has to progress in a piecemeal manner. The author also concludes that the notion of ‘human nature’ cannot be regarded as a moral desideratum.South African Journal of Philosophy 2014, 33(2): 155–16
A note on ordinal exponentiation and derivatives of normal functions
No full textMichael Rathjen and the present author have shown that Π11‐bar induction is equivalent to (a suitable formalization of) the statement that every normal function has a derivative, provably in ACA0. In this note we show that the base theory can be weakened to RCA0. Our argument makes crucial use of a normal function f with f(α)≤1+α² and f′(α)=ωωα. We shall also exhibit a normal function g with g(α)≤1+α·2 and g′(α)=ω1+α
Athanasius' contra arianos iv: a reconsideration
No full textThe purpose of this thesis is to provide a through reconsideration of the treatise Oratio IV Contra Arianos (hereinafter referred to as CAR IV), which historically is attributed to St. Athanasius. This reconsideration addresses three main areas of inquiry:1. Is it defensible to consider Athanasius to be the author of CAR IV in terms of linguistics and theology?2. Since the Athanasian premise is not universally accepted, what other authors are suggested by patristics scholars?3. Regardless of authorship, what theological value does CAR IV hold for the contemporary reader? It is this author's contention that CAR IV, though a lesser-known writing of the Nicene period, is a very significant treatise. CAR IV offers a valuable insight into the theologically rich and complex world of the fourth century church. In CAR IV, by way of refutation, we are introduced to a view as radical and persistent as Arianism but less often discussed - modalistic monarchianism. An understanding of all the varied doctrines that did battle at Nicea leads to a greater appreciation for the endurance of the tradition expressed in the Nicene creed. In conclusion, the present author finds the argument that CAR IV is genuinely Athanasian but separate from the other three Orations to be the most convincing theory yet expounded. CAR IV would be more properly titled Contra Marcellum. Perhaps Athanasius never gave this title to the work in deference to Marcellus. Only Athanasius, Marcellus' friend, would demonstrate this consideration. It is also suggested that CAR IV was an incomplete rough draft. The author of this thesis agrees with this reasoning also, and after contemplation would further this explanation by hypothesizing that CAR IV was an incomplete text of Athanasius that was collected and arranged in its current form posthumously by students of the Bishop
Musikstädte as real and imaginary soundscapes: urban musical images as literary motifs in twentieth-century German modernism
No full textPhDThis study examines German literary images of musical life as part of the wider sound identity of the modern German city at the turn of the twentieth century. Focussing on a forty-year period from 1890 to 1930, synonymous with the emergence of the modern German metropolis as an aesthetic object, the project assesses, compares and contrasts how musical life in the Musikstädte was perceived and portrayed by writers in an increasingly noisy urban environment. How does urban musical life influence and condition city writings? What are the differences and similarities between the writings on various musical cities? Can an urban textual sound identity be derived from these differences and similarities? The approach employed to answer these questions is a new, cross-disciplinary one to urban sound in literature, moving beyond reading the key sounds of the urban soundscape using urban musicology, sensorial anthropology and cultural poetics towards a literary contextualisation of the urban aural experience.
The literary motifs of the symphony, the gramophone and urban noise are put under the spotlight through the analysis of a wide range of modernist works by authors who have a special relationship with music. At the centre of this analysis are the Kaffeehausliteratur authors Hermann Bahr, Alfred Polgar and Peter Altenberg, the then Munich-based author Thomas Mann and the lesser known René Schickele. The analysis of these particular works is framed in the music-geographical context of the Musikstadt and literary underpinnings of this topos, ranging from Ingeborg Bachmann to Hans Mayer and, once again, Thomas Mann. In analysing these texts, the methodological approach devised by Strohm, who identifies the blending of a range of urban sounds as a definition of urban space and identity, is applied. His ideas combine historical literary
analysis, musical history and urban sociology. They are rarely used in the analysis of the auditory environment.Arts and Humanities Research Council
Westfield TrustWestfield Trust Studentship
Arts and Humanities Reseach Council (AHRC
National Socialistische Beweging in Nederland (N.S.B.)
No full textBooklet marked “DE N.S.B. EN ONS CHRISTELIJK VOLKSKARAKTER” across top, image of man holding one arm up, 15 pages.
Information Provided by Michael D. Bulmash: Anton Mussert’s name appears on this N.S.B. pamphlet cover and is possibly its author. He was a leader of the National Socialist Movement in the Netherlands. Found guilty of treason at the end of WWII, he was executed in 1946.https://digital.kenyon.edu/bulmash/2621/thumbnail.jp
PESI - a taxonomic backbone for Europe
No full textThis is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The attached file is the published version of the article.NHM Repositor
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