14 research outputs found
Bibliographics for the 983 eprints in the live archives of E-LIS : trends and status report up to 7th July 2004, based on author-self-archiving metadata
No full textThe priority for ideas and philosophy related to "Network Theory" have been traced back and documented by Braun(2004),and credit goes to Karinthy(1929).The IT has empowered to realise it, as the most practical phenomena and it is no more a humour. The OAI (Open Archives Initiatives)and ACIS (Academic Contributor Information System)are progressive in the direction ,which may lead to realise the "Collective Genius" at global level. Focus of present study is on Author-Self-Archiving (A-S-A)Metadata of the 983 Eprints in the Live Archives of the E-LIS (EPrints of Library and Information Science),which were approved till 7th July 2004.The A-S-A Metadata was used for librametric analysis. Self-explanatory bibliographics are illustrated.The highlights include: Conference papers (34%); highest approval, June 2004 (28%); published archives (76%);not refereed (52%); not in public domain (60%); highest self-archiving-author (De Robbio, Antonella).The Nos. of EPrints having single JITA domain specifications were: Theoretical and general aspects of libraries and information(27); Information use and sociology of information(80);Users,literacy and reading(13);Libraries as physical collections(30);Publishing and legal issues(57);Management(13);Industry, profession and education(36);Information sources, supports, channels(113) ; Information treatment for information services, Information functions and techniques (101); Technical services libraries, archives and museums(25); Housing technologies(1); Information technology and library technology(92); and Inter-domainery (395) i.e. having specifications of two or more than two JITA classes
Nanostructural characterization of large-scale porous alumina fabricated via anodizing in arsenic acid solution
No full textAnodizing of aluminum in an arsenic acid solution is reported for the fabrication of anodic porous alumina. The highest potential difference (voltage) without oxide burning increased as the temperature and the concentration of the arsenic acid solution decreased, and a high anodizing potential difference of 340 V was achieved. An ordered porous alumina with several tens of cells was formed in 0.1-0.5 M arsenic acid solutions at 310-340 V for 20 h. However, the regularity of the porous alumina was not improved via anodizing for 72 h. No pore sealing behavior of the porous alumina was observed upon immersion in boiling distilled water, and it may be due to the formation of an insoluble complex on the oxide surface. The porous alumina consisted of two different layers: a hexagonal alumina layer that contained arsenic from the electrolyte and a pure alumina honeycomb skeleton. The porous alumina exhibited a white photoluminescence emission at approximately 515 nm under UV irradiation at 254 nm
Self-ordered Porous Alumina Fabricated via Phosphonic Acid Anodizing
No full textSelf-ordered periodic porous alumina with an undiscovered cell diameter was fabricated via electrochemical anodizing in a new electrolyte, phosphonic acid (H3PO3). High-purity aluminum plates were anodized in phosphonic acid solution under various operating conditions of voltage, temperature, concentration, and anodizing time. Phosphonic acid anodizing at 150-180 V caused the self-ordering behavior of porous alumina, and an ideal honeycomb nanostructure measuring 370-440 nm in cell diameter was successfully fabricated on the aluminum substrate. Conversely, disordered porous alumina grew at below 140 V, and anodizing at above 190 V caused local thickening due to oxide burning. Two-step phosphonic acid anodizing allows the fabrication of high aspect ratio ordered porous alumina. HPO32 anions originated from the electrolyte were incorporated into the porous oxide during anodizing. Consequently, a double-layered porous alumina consisting of a thick outer layer containing incorporated HPO32 anions, and a thin inner layer without anions was constructed via phosphonic acid anodizing
Transcriptional Suppression of Diabetic Nephropathy with Novel Gene Silencer Pyrrole-Imidazole Polyamides Preventing USF1 Binding to the TGF-β1 Promoter
No full textUpstream stimulatory factor 1 (USF1) is a transcription factor that is increased in high-glucose conditions and activates the transforming growth factor (TGF)-β1 promoter. We examined the effects of synthetic pyrrole-imidazole (PI) polyamides in preventing USF1 binding on the TGF-β1 promoter in Wistar rats in which diabetic nephropathy was established by intravenous administration of streptozotocin (STZ). High glucose induced nuclear localization of USF1 in cultured mesangial cells (MCs). In MCs with high glucose, USF1 PI polyamide significantly inhibited increases in promoter activity of TGF-β1 and expression of TGF-β1 mRNA and protein, whereas it significantly decreased the expression of osteopontin and increased that of h-caldesmon mRNA. We also examined the effects of USF1 PI polyamide on diabetic nephropathy. Intraperitoneal injection of USF1 PI polyamide significantly suppressed urinary albumin excretion and decreased serum urea nitrogen in the STZ-diabetic rats. USF1 PI polyamide significantly decreased the glomerular injury score and tubular injury score in the STZ-diabetic rats. It also suppressed the immunostaining of TGF-β1 in the glomerulus and proximal tubules and significantly decreased the expression of TGF-β1 protein from kidney in these rats. These findings indicate that synthetic USF1 PI polyamide could potentially be a practical medicine for diabetic nephropathy
Free amino acid concentrations in blood cells of two brothers with gyrate atrophy of the choroid and retina with hyperornithinaemia
No full textA development of a molecularly imprinted polymer: Specific for ochratoxin A: Theoretical and sensor applications
No full textIn this work the development of two molecularly imprinted polymers, specific
for ochratoxin A, is presented. Ochratoxin A is produced by several
Aspergillus and Penicillium species and is common in cereals and other
starch rich foods and has also been found in coffee, dried fruits, wine, beer
and meats. It demonstrates potent teratogenic, immunosuppressive,
mutagenic and carcinogenic properties. The toxin is also linked to Balkan
Endemic Nephropathy, a chronic kidney disease found in South-Eastern
Europe. Due to this the European Union has set limits on foodstuffs ranging
between 2-10 ng g-1. Therefore the requirement of a simple and inexpensive
biosensor to monitor this legislation is a necessity. Currently detection is
performed by chromatographic methods such as HPLC, and by ELISA
formats.
In this work two polymeric materials, rationally designed by computational
modelling and synthesised using molecular imprinting, are studied. The
modelling is complimented with a Nuclear Magnetic Resonance (NMR) study.
The first polymer (Polymer A) consisted of 1 mol of acrylamide and 1 mol of
methacrylic acid to 1 mol of template. This material demonstrated an unusual
binding mechanism, working solely in aqueous solvents. A theoretical
mechanism for this binding is presented and discussed.
The second polymer, again rationally designed, but under different conditions,
consisted of 1 mol of N,N- diethylamino ethyl methacrylate (DEAEM) to 1 mol
of template. This polymer demonstrated high affinity for the template in
acetonitrile.
Polymer A is used in combination with an ion-exchange SPE protocol
(developed for this purpose) for the extraction of OTA from maize.
Both polymer compositions are used in development of a MIP membrane
optical sensor, with partial success seen in the detection of OTA in grape juice
and white wine
The International Linear Collider: Report to Snowmass 2021
No full textThe International Linear Collider (ILC) is on the table now as a new global
energy-frontier accelerator laboratory taking data in the 2030s. The ILC
addresses key questions for our current understanding of particle physics. It
is based on a proven accelerator technology. Its experiments will challenge the
Standard Model of particle physics and will provide a new window to look beyond
it. This document brings the story of the ILC up to date, emphasizing its
strong physics motivation, its readiness for construction, and the opportunity
it presents to the US and the global particle physics community.Comment: 356 pages, Large pdf file (40 MB) submitted to Snowmass 2021; v2
references to Snowmass contributions added, additional authors; v3 references
added, some updates, additional author
