170,170 research outputs found
Rationalization of washing process in buffer tanks
No full textNamen diplomske naloge je določiti optimalni čas pranja pufrnih rezervoarjev, zmanjšati porabo pralne vode in hkrati količino vode, ki se mora očistiti na industrijski čistilni napravi. V sklopu čistilne naprave v podjetju, ki se ukvarja s proizvodnjo pralnih in drugih kemičnih sredstev, imamo na voljo vakuumski uparjalnik, zato želimo maksimizirati porabo destilata namesto vodovodne vode. V vzorcih pralne vode se po pranju opreme še vedno nahajajo površinsko aktivne snovi in druge kemikalije. S sistemskim pristopom vzorčenja in s pomočjo hitrih analiz (pH, motnost, prevodnost, penjenje, kivetni testi za tenzide in sulfate, lomni količnik) smo določili optimalne pogoje pranja za posamezen polizdelek v pufrnem rezervoarju. Pralna voda mora biti po čiščenju opreme bistra, brezbarvna, brez vonja in pene. Poleg tega je zahtevan še nevtralni pH (med 5,5 in 8,5) in lomni količnik vrednosti 0,5 °Brix ali manj. Ugotovili smo, da je prevodnost tisti parameter, ki nam pove zelo veliko o čistosti pralne vode. Po določitvi optimalnih pogojev pranja pri posameznih polizdelkih se je prevodnost namreč gibala v podobnem območju, tj. med 490 µS/cm in 540 µS/cm. Ugotovili smo, da smo pranje največkrat ponavljali v pufrnih rezervoarjih 5 in 7. Ta dva rezervoarja sta zaradi svoje starosti najbolj kritična, saj je poraba pralne vode zaradi večkratnih ponovitev pranj posledično zelo velika. Z uvajanjem protipenilnega sredstva direktno v cev pralne vode smo na zelo penečem polizdelku porabo vode zmanjšali za približno 70 % začetne porabe.The purpose of the thesis is to determine the optimal time for washing buffer tanks, to reduce the consumption of washing water and at the same time the amount of water that must be cleaned at the industrial treatment plant. As part of the treatment plant in the company, which is engaged in the production of detergents and other chemical agents, we have a vacuum evaporator available in order to maximize the consumption of distillate instead of tap water. In the washing water samples there are still surfactants and other chemicals present after washing the equipment. Using systematic sampling approach and with the help of fast analyzes (pH, turbidity, conductivity, foaming, cuvette tests for surfactants and sulfates, refractive index), we determined the optimal washing conditions for each semi-finished product in buffer tank. After cleaning of equipment, washing water must be: clear, colorless, odorless and foamless. In addition, a neutral pH (between 5.5 and 8.5) and refractive index of 0,5 ° Brix or less, are required. We found out that conductivity is the parameter which tells a lot about the purity of washing water. After determining the optimal washing conditions for individual semi-finished products, the conductivity was in a similar range, ie. between 490 µS/cm and 540 µS/cm. We found out that washing was most often repeated in buffer tanks 5 and 7. Mentioned two tanks are the most critical due to their age, as the consumption of washing water is consequently very high due to repeated repetitions of washing. By implementing the antifoam directly into the washing water pipe, water consumption on the highly foaming semi-finished product reduced for approximately 70 % of the initial consumption
Standard Audit File for Tax – SAF-T
No full textConsidering the role of SAF-T Standard Audit File for Tax (D406) in terms of taxpayers’ relation with the National Agency of Fiscal Administration and the fact that, starting with January 1, 2025, a significant category of taxpayers will be required to submit the D406 informative statement, by this article we aim to present the categories of taxpayers who must submit the SAF-T file, those who are not required to submit the statement, and the structure of this file. It is also essential to know aspects of consistency tests that can be applied to ensure compliance upon submittal. The Standard Audit File for Tax represents a means of evidence, being an additional reason to be aware of the importance of declaring correct information that reflects reality
Parallel file system analysis through application I/O tracing
No full textInput/Output (I/O) operations can represent a significant proportion of the run-time of parallel scientific computing applications. Although there have been several advances in file format libraries, file system design and I/O hardware, a growing divergence exists between the performance of parallel file systems and the compute clusters that they support. In this paper, we document the design and application of the RIOT I/O toolkit (RIOT) being developed at the University of Warwick with our industrial partners at the Atomic Weapons Establishment and Sandia National Laboratories. We use the toolkit to assess the performance of three industry-standard I/O benchmarks on three contrasting supercomputers, ranging from a mid-sized commodity cluster to a large-scale proprietary IBM BlueGene/P system. RIOT provides a powerful framework in which to analyse I/O and parallel file system behaviour—we demonstrate, for example, the large file locking overhead of IBM's General Parallel File System, which can consume nearly 30% of the total write time in the FLASH-IO benchmark. Through I/O trace analysis, we also assess the performance of HDF-5 in its default configuration, identifying a bottleneck created by the use of suboptimal Message Passing Interface hints. Furthermore, we investigate the performance gains attributed to the Parallel Log-structured File System (PLFS) being developed by EMC Corporation and the Los Alamos National Laboratory. Our evaluation of PLFS involves two high-performance computing systems with contrasting I/O backplanes and illustrates the varied improvements to I/O that result from the deployment of PLFS (ranging from up to 25× speed-up in I/O performance on a large I/O installation to 2× speed-up on the much smaller installation at the University of Warwick)
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
File forensics for RAW camera image formats
No full textRecent research in multimedia forensics has developed a variety of methods to detect image tampering and to identify the origin of image files. Many of these techniques are based on characteristics in the JPEG format, as it is the most used file format for digital images. In recent years RAW image formats have gained popularity among amateur and professional photographers. This increase in their use and possible misuse makes these file formats an important subject to file forensic examinations. The aim of this paper is to explore to which extend methods previously developed for images in JPEG format can be applied to RAW image formats
Performance optimization for managing massive numbers of small files in distributed file systems
No full textThe processing of massive numbers of small files is a challenge in the design of distributed file systems. Currently, the combined-block-storage approach is prevalent. However, the approach employs the traditional file systems such as ExtFS and may cause inefficiency when accessing small files randomly located in the disk. This paper focuses on optimizing the performance of data servers in accessing massive numbers of small files. We present a Flat Lightweight File System (iFlatLFS) to manage small files, which is based on a simple metadata scheme and a flat storage architecture. iFlatLFS is designed to substitute the traditional file system on data servers and can be deployed underneath distributed file systems that store massive numbers of small files. iFlatLFS can greatly simplify the original data access procedure. The new metadata proposed in this paper occupies only a fraction of the metadata size based on traditional file systems. We have implemented iFlatLFS in CentOS 5.5 and integrated it into an open source Distributed File System (DFS), called Taobao FileSystem (TFS), which is developed by a top B2C service provider, Alibaba, in China and is managing over 28.6 billion small photos. We have conducted extensive experiments to verify the performance of iFlatLFS. The results show that when the file size ranges from 1KB to 64KB, iFlatLFS is faster than Ext4 by 48% and 54% on average for random read and write in the DFS environment, respectively. Moreover, after iFlatLFS is integrated into TFS, iFlatLFS-based TFS is faster than the existing Ext4-based TFS by 45% and 49% on average for random read access and hybrid access (the mix of read and write accesses), respectively
PESI - a taxonomic backbone for Europe
No full textThis is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The attached file is the published version of the article.NHM Repositor
Modelling the magnetic activity and filtering radial velocity curves of young Suns : the weak-line T Tauri star LkCa 4
No full textSGG acknowledges support from the Science & Technology Facilities Council (STFC) via an Ernest Rutherford Fellowship [ST/J003255/1]. SHPA acknowledges financial support from CNPq, CAPES and Fapemig.We report results of a spectropolarimetric and photometric monitoring of the weak-line T Tauri star LkCa 4 within the Magnetic Topologies of Young Stars and the Survival of close-in giant Exoplanets (MaTYSSE) programme, involving ESPaDOnS at the Canada–France–Hawaii Telescope. Despite an age of only 2 Myr and a similarity with prototypical classical T Tauri stars, LkCa 4 shows no evidence for accretion and probes an interesting transition stage for star and planet formation. Large profile distortions and Zeeman signatures are detected in the unpolarized and circularly polarized lines of LkCa 4 using Least-Squares Deconvolution (LSD), indicating the presence of brightness inhomogeneities and magnetic fields at the surface of LkCa 4. Using tomographic imaging, we reconstruct brightness and magnetic maps of LkCa 4 from sets of unpolarized and circularly polarized LSD profiles. The large-scale field is strong and mainly axisymmetric, featuring a ≃2 kG poloidal component and a ≃1 kG toroidal component encircling the star at equatorial latitudes – the latter making LkCa 4 markedly different from classical T Tauri stars of similar mass and age. The brightness map includes a dark spot overlapping the magnetic pole and a bright region at mid-latitudes – providing a good match to the contemporaneous photometry. We also find that differential rotation at the surface of LkCa 4 is small, typically ≃5.5 times weaker than that of the Sun, and compatible with solid-body rotation. Using our tomographic modelling, we are able to filter out the activity jitter in the radial velocity curve of LkCa 4 (of full amplitude 4.3 km s−1) down to an rms precision of 0.055 km s−1. Looking for hot Jupiters around young Sun-like stars thus appears feasible, even though we find no evidence for such planets around LkCa 4.Peer reviewe
Escalating and De-escalating Therapy for Early-Stage HER2-Positive Breast Cancer
No full textUntreated, HER2+ disease is the most aggressive breast cancer phenotype; however, the development of multiple highly effective HER2-targeting drugs has transformed treatment and survival. These drugs include the anti-HER2 monoclonal antibodies trastuzumab and pertuzumab; small molecule inhibitors lapatinib, neratinib, and tucatinib; and antibody-drug conjugates trastuzumab emtansine (T-DM1) and now trastuzumab deroxtecan. More complex regimens using these drugs continue to improve outcomes, but the incremental benefits of these advances are often modest. Improved outcomes came from the addition of HER2-targeted therapies to conventional chemotherapy, beginning with trastuzumab, then pertuzumab added to trastuzumab, or with neratinib given for the year after trastuzumab. Neoadjuvant, or preoperative, administration of chemotherapy plus HER2-targeting allows surgical deescalation and tailoring treatment by pathologic complete response (pCR) to therapy. Patients with pCR after conventional therapy have excellent outcomes; what we now know is that the poorer outcomes associated with residual disease can be ameliorated with adjuvant T-DM1. However, as we have developed more complex, effective, and expensive therapy to maximize outcomes, it is also true that we are overtreating many patients. In stage I HER2+ breast cancer, there are excellent outcomes with paclitaxel plus trastuzumab or T-DM1 alone. Higher clinical stage HER2+ disease is still treated aggressively, although intrinsic subtype or activated immune tumor microenvironment may identify those with augmented treatment response or better outcome. It is likely that future strategies to escalate and de-escalate treatment with less chemotherapy, fewer anti-HER2 drugs, or shorter duration will depend upon integrated clinical and genomic modeling
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Towards Open Tracing of P2P File Sharing Systems
No full textSince the release of Napster in 1999, peer-to-peer file-sharing has enjoyed a dramatic rise in popularity. A 2000 study by Plonka on the University of Wisconsin campus network found that file-sharing accounted for a comparable volume of traffic to web applications, while a 2002 study by Saroiu et al. on the University of Washington campus network found that file-sharing accounted for more than treble the volume of web traffic observed, thus affirming the significance of P2P in the context of Internet traffic. Empirical studies of peer-to-peer traffic are essential for supporting the design of next-generation peer-to-peer systems, informing the provisioning of network infrastructure and underpinning the policing of peer-to-peer systems. This paper surveys existing work in the field of peer-to-peer monitoring and based upon this assessment of the state-of-the-art describes the design and implementation of the Open P2P tracing system, which aims to improve the research community’s understanding of P2P file sharing systems by providing continuous and up-to-date traffic data which is anonymized and made freely accessible to all interested parties. Data from this system has been used in a variety of projects and papers, which are used to illustrate the broad range of research that can benefit from an open tracing system
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