30,898 research outputs found
Locomotion modulates specific functional cell types in the mouse visual thalamus
No full textThe visual system is composed of diverse cell types that encode distinct aspects of the visual scene and may form separate processing channels. Here we present further evidence for that hypothesis whereby functional cell groups in the dorsal lateral geniculate nucleus (dLGN) are differentially modulated during behavior. Using simultaneous multi-electrode recordings in dLGN and primary visual cortex (V1) of behaving mice, we characterized the impact of locomotor activity on response amplitude, variability, correlation and spatiotemporal tuning. Locomotion strongly impacts the amplitudes of dLGN and V1 responses but the effects on variability and correlations are relatively minor. With regards to tunings, locomotion enhances dLGN responses to high temporal frequencies, preferentially affecting ON transient cells and neurons with nonlinear responses to high spatial frequencies. Channel specific modulations may serve to highlight particular visual inputs during active behaviors.BMIThis article is licensed under a Creative Commons Attribution 4.0 International Licens
AN ECONOMIC EVALUATION OF LOW INVESTMENT SWINE PRODUCTION SYSTEMS
No full textThis publication summarizes an evaluation of smaller and lower investment swine production systems. The systems analyzed range from pasture operations with production during the warmer months to rather intense year-round use of remodeled buildings. In each case the system emphasizes use of facilities that can be constructed and remodeled by the farm operator. The report includes one section for each type of hog production: feeder pig production, farrow-to-finish operations and hog finishing.Livestock Production/Industries,
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
C*-algebras have a quantitative version of Pełczyński's property (V)
No full textsummary:A Banach space has Pełczyński's property (V) if for every Banach space every unconditionally converging operator is weakly compact. H. Pfitzner proved that -algebras have Pełczyński's property (V). In the preprint (Krulišová, (2015)) the author explores possible quantifications of the property (V) and shows that spaces for a compact Hausdorff space enjoy a quantitative version of the property (V). In this paper we generalize this result by quantifying Pfitzner's theorem. Moreover, we prove that in dual Banach spaces a quantitative version of the property (V) implies a quantitative version of the Grothendieck property
The impact of pre-farrow rotavirus immunization protocols on viral shedding and piglet performance
No full textThis thesis is comprised of five chapters, with the first and last being the general introduction and conclusions, respectively. The second chapter summarizes the findings from a systematic literature review on rotavirus immunization techniques and effects. The third and fourth chapters discuss original research aimed to assess the impacts of several methods of pre-farrow feedback and vaccination.
The objective of the literature review in chapter 2 was to summarize our current knowledge of rotavirus immunization methods in swine and describe their measurable impacts on performance metrics, viral shedding, and clinical presentations. It resulted in the identification of several publications describing feedback protocols and vaccination platforms. There was very little meaningful evidence of the impact of these methods on piglets when given to sows or gilts pre-farrow. Anecdotal evidence suggested a reduced prevalence of diarrhea and improved pre-farrow weight gain when controlled feedback protocols were implemented on sow farms.
The objectives of chapter 3 were to determine the pattern of rotavirus shedding in gilts after several controlled feedback protocols, termed natural planned exposure (NPE). Additionally, chapter 3 aimed to assess the effects on piglet weaning weight, pre-weaning mortality, and rotavirus (RV) shedding. A total of 70 pregnant gilts were enrolled and allocated into 4 groups. Group 1 was given NPE at 5, 4, and 3 weeks pre-farrow (WPF); Group 2 at 5 and 3 WPF; and Group 3 at 5 WPF only. Group 4 (control group) did not receive any NPE. Samples from 46 gilts and litters (5 piglets per litter) were tested at 12 sample times. Piglets were sampled weekly from 24 hours of age until 6 weeks of age and tested by quantitative reverse transcription-polymerase chain reaction (qRT-PCR) for rotavirus A (RVA), rotavirus B (RVB), and rotavirus C (RVC). There was a significant improvement in weaning weight of piglets born to gilts that received 3 NPE administrations compared to a lower number or no administrations of NPE. RVA and RVB shedding from piglets were well-controlled in the farrowing room regardless of treatment group, but RVC was observed as early as 1 week old. This study was conducted on a single farm, and the results should be carefully interpreted with knowledge of variations in farms and systems. Overall, this study showed that three doses of NPE to gilts pre-farrowing resulted in valuable benefits for swine producers. Additionally, it contributed to our current knowledge of rotavirus shedding dynamics in both adult animals and piglets.
The objective of chapter 4 was to compare rotavirus shedding and performance of piglets from gilts immunized using NPE or an RNA particle vaccine (RPV) prior to farrowing following initial NPE pre-breeding. A final total of 117 farrowed gilts and their piglets were enrolled into 4 groups. All gilts received two administrations of NPE prior to breeding. Gilts in group 1 were later given three NPE administrations at 5, 4, and 3 WPF. Group 2 was dosed with an RNA particle vaccine (RPV) at 5 and 3 WPF and group 3 at 1 WPF only. Group 4 (control group) did not receive any NPE or RPV. Fecal samples from gilts and fecal swabs from their piglets were tested for RVA, RVB, and RVC by qRT-PCR. The 117 gilt samples were tested individually at 5 sampling points from pre-breeding to entry into the farrowing rooms. Piglet samples were pooled by litter (3 piglets sampled per litter) and tested at 3, 7, 14, and 21 days of age. The clinical and production impact of the treatments were assessed by comparing average adjusted weaning weights, the percentage of piglets weighing in the bottom 10% of study piglets at weaning, the percentage of piglets placed in the nursery, and the percentage of litters with the presence of diarrhea. No statistically significant differences were identified but there appeared to be several interesting numerical trends that are both biologically plausible and consistent among treatment groups. The control group, which received no pre-farrow immunization, had the highest percentage of litters with diarrhea at all time points and overall in the farrowing house. A numerical trend was also observed on average cycle threshold (Ct) values for RVC in piglets. Interestingly, the control group had the lowest numerical average Ct value at 7, 14, and 21 days of age. Ct values for RVA were consistently lower than for RVC in the stock solution and NPE gruel. This likely correlated to a lower level of RVC exposure in all gilts pre-breeding and group 1 gilts pre-farrow. This may have an inverse correlation to the higher levels of shedding of RVC in piglets. The lack of statistical significance between treatment groups with regard to diarrhea and weights in the piglets may be attributed to sample size, lack of sufficient natural rotavirus challenge, pre-breeding NPE in all gilts, or a variety of other reasons. Replication of this study with a larger sample size, using a challenge model, or relocated to a farm with increased natural rotavirus clinical challenges may yield different results. If beneficial under different conditions, the RPV would eliminate many of the risks associated with NPE administration, including continuous introduction of live virus on-farm, potential spread of other pathogens, difficulty of isolating on-farm strains, and labor and cost of producing NPE material.
Limitations of the original research chapters include the use of qRT-PCR to measure the levels of RVA and RVC in the stock solution and gruel and to monitor RV shedding, rather than techniques with the ability to differentiate live and non-viable virus. Additionally, these studies were performed on an all-gilt breeding farm. It may be more challenging to appreciate differences in treatment groups on a multiparous sow farm due to the higher level of immunity correlated to increasing parity. These immunization protocols were designed to be applicable in a field setting for routine rotavirus immunization, though their feasibility must be carefully considered before implementation on each individual farm
Illuminaçao Apologetica do retrato de Morteçor en que aparecem com mais vivas côres os erros do author do novo Methodo, e seu Apologista ...
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Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A ± 12-A High-Side Current Sensor With 25 V Input CM Range and 0.35% Gain Error From −40 °C to 85 °C
No full textThis letter presents the most accurate shunt-based high-side current sensor ever reported. It achieves a 25 V input common-mode range from a single 1.8-V supply by using a beyond-the-rails ADC. A hybrid analog/digital temperature compensation scheme is proposed to simplify the circuit implementation while maintaining the state-of-the-art accuracy. Over a ±12-A current range, the sensor exhibits 0.35% gain error from -40 °C to 85 °C with 3× better power efficiency.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
Improving the Regulatory Analysis of the Cooling Water Intake Structure Rule: What Does an Economist Want?
No full textAs part of an edited volume devoted to the usefulness of benefit-cost analysis to inform regulatory review, this chapter presents a case study of the regulation of cooling water intake structures (CWIS) at existing power plants. The chapter first focuses on the consistency of the CWIS benefit-cost analysis with quality criteria to which the agency might have been expected to adhere. Second, criteria and outcomes with respect to decision rules for the selected alternatives are investigated. Finally, the challenge faced by agency analysis is described due to the difficulty in linking ecological and economic impacts. Suggestions for improvement are noted. As of the date of writing, the regulation is under review by the Supreme Court.Water, regulation, benefit-cost
Panel 5: Access to Justice
No full textPANEL V: ACCESS TO JUSTICE: Moderator: Lorne Sossin, Dean, Osgoode Hall Law School; Speaker: Janet Mosher, Professor, Osgoode Hall Law School, Access to Justice Amid Threats of Contagion ; Speaker: Trevor Farrow, Professor, Osgoode Hall Law School, What is Access to Justice? ; Discussant: Michael Trebilcock, Professor, Faculty of Law, University of Toronto
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