232 research outputs found
Intraspecific morphological variation in Cichlidogyrus (Monogenea) parasitizing two cichlid hosts from Lake Tanganyika exhibiting different dispersal capacities
No full textsponsorship: The authors are grateful to many colleagues and friends who assisted with the sample collections during the fieldtrip in Burundi in 2013 and in the Democratic Republic of the Congo in 2016. We thank C. Sturmbauer and S. Koblmuller (University of Graz, Austria), W. Salzburger (University of Basel, Switzerland), D. Muzumani Risasi (CRH-Uvira) for their precious help with cichlid identification; M. Reichard and R. Blaz. ek (Czech Academy of Sciences, Czech Republic) for their help with fish collection, dissection and providing us the photographs of cichlid species during the fieldtrip; A. Meyer (University of Konstanz, Germany), G. Banyankimbona (University of Burundi) and the Schreyen-Brichard family (Burundi/Belgium) for the sample collection and fish identification; P. Masilya Mulungula, T. Mulimbwa N'sibula, V. Lumami Kapepula, E. Bahane Byaragi, S. Kambale Mukeranya and F. Muterezi Bukinga (CRH-Uvira) for co-organizing the field work and their scientific contribution on Tanganyikan cichlids; S.. Mas. ova', V. Micha'lkova', E. R. ehulkova', I. Pr.ikrylova', L. Raisingerova' and N. Kmentova' (Masaryk University, Brno, Czech Republic) for their help with fish dissection, parasite isolation and fixation. The first author thanks L. S. tarhova' Serbina (Masaryk University, Brno, Czech Republic) for stimulating discussions and constructive suggestions and critics related to the geomorphometry. The kind help of K. Civa' n. ova', E. Jirounkova', K. Koukalova', and especially M. Seifertova' (Masaryk University, Brno, Czech Republic), who provided the necessary background in genetics and an unconditional assistance in the molecular laboratory, is acknowledged. Finally, the authors would like to thank E. Verheyen, T. Backeljau, and all the colleagues working at the Royal Belgian Institute of Natural Sciences (RBINS, Brussels), M. Parrent from the Royal Museum for Central Africa (RMCA, Tervuren), T. Artois, M.W.P. Jorissen, L. Steenaerts and T. Van Dijck (Hasselt University, Diepenbeek, Belgium) for their kind hospitality and for the precious help they provided during the stay in Belgium. This research was funded by the Czech Science Foundation project no. P505/12/G112-European Centre of Ichtyoparasitology (ECIP) and C.R., M.V.S. and M.P.M.V. were further supported by standard project GA19-13573S. The funder had no role in study design, data collection and analyses, decision to publish, or preparation of the manuscript. (Czech Science Foundation|P505/12/G112, GA19-13573S)status: Publishe
EDITORIAL The taxonomic impediment: a shortage of taxonomists, not the lack of technical approaches
No full textEngel, Michael S, Ceríaco, Luis M P, Daniel, Gimo M, Dellapé, Pablo M, Löbl, Ivan, Marinov, Milen, Reis, Roberto E, Young, Mark T, Dubois, Alain, Agarwal, Ishan, Lehmann A., Pablo, Alvarado, Mabel, Alvarez, Nadir, Andreone, Franco, Araujo-Vieira, Katyuscia, Ascher, John S, Baêta, Délio, Baldo, Diego, Bandeira, Suzana A, Barden, Phillip, Barrasso, Diego A, Bendifallah, Leila, Bockmann, Flávio A, Böhme, Wolfgang, Borkent, Art, Brandão, Carlos R F, Busack, Stephen D, Bybee, Seth M, Channing, Alan, Chatzimanolis, Stylianos, Christenhusz, Maarten J M, Crisci, Jorge V, D'elía, Guillermo, Da Costa, Luis M, Davis, Steven R, De Lucena, Carlos Alberto S, Deuve, Thierry, Fernandes Elizalde, Sara, Faivovich, Julián, Farooq, Harith, Ferguson, Adam W, Gippoliti, Spartaco, Gonçalves, Francisco M P, Gonzalez, Victor H, Greenbaum, Eli, Hinojosa-Díaz, Ismael A, Ineich, Ivan, Jiang, Jianping, Kahono, Sih, Kury, Adriano B, Lucinda, Paulo H F, Lynch, John D, Malécot, Valéry, Marques, Mariana P, Marris, John W M, Mckellar, Ryan C, Mendes, Luis F, Nihei, Silvio S, Nishikawa, Kanto, Ohler, Annemarie, Orrico, Victor G D, Ota, Hidetoshi, Paiva, Jorge, Parrinha, Diogo, Pauwels, Olivier S G, Pereyra, Martín O, Pestana, Lueji B, Pinheiro, Paulo D P, Prendini, Lorenzo, Prokop, Jakub, Rasmussen, Claus, Rödel, Mark-Oliver, Rodrigues, Miguel Trefaut, Rodríguez, Sara M, Salatnaya, Hearty, Sampaio, Íris, Sánchez-García, Alba, Shebl, Mohamed A, Santos, Bruna S, Solórzano-Kraemer, Mónica M, Sousa, Ana C A, Stoev, Pavel, Teta, Pablo, Trape, Jean-François, Dos Santos, Carmen Van-Dúnem, Vasudevan, Karthikeyan, Vink, Cor J, Vogel, Gernot, Wagner, Philipp, Wappler, Torsten, Ware, Jessica L, Wedmann, Sonja, Zacharie, Chifundera Kusamba (2021): EDITORIAL The taxonomic impediment: a shortage of taxonomists, not the lack of technical approaches. Zoological Journal of the Linnean Society 193 (2): 381-387, DOI: 10.1093/zoolinnean/zlab072, URL: https://academic.oup.com/zoolinnean/article/193/2/381/637438
Re-thinking residential mobility : linking lives through time and space
No full textRory Coulter’s work on this paper was partly supported by an Economic and Social Research Council grant [ES/L009498/1]. Maarten van Ham’s contribution was supported by funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007–2013) / ERC Grant Agreement n. 615159 (ERC Consolidator Grant DEPRIVEDHOODS, Socio-spatial inequality, deprived neighbourhoods, and neighbourhood effects); and from the Marie Curie programme under the European Union’s Seventh Framework Programme (FP/2007–2013) / Career Integration Grant no. PCIG10-GA-2011-303728 (CIG Grant NBHCHOICE, Neighbourhood choice, neighbourhood sorting, and neighbourhood effects). Allan Findlay’s work was supported by an Economic and Social Research Council grant [ES/K007394/1].While researchers are increasingly re-conceptualizing international migration, far less attention has been devoted to re-thinking short-distance residential mobility and immobility. In this paper we harness the life course approach to propose a new conceptual framework for residential mobility research. We contend that residential mobility and immobility should be re-conceptualized as relational practices that link lives through time and space while connecting people to structural conditions. Re-thinking and re-assessing residential mobility by exploiting new developments in longitudinal analysis will allow geographers to understand, critique and address pressing societal challenges.Peer reviewe
A multi-factor approach to understanding socio-economic segregation in European capital cities
No full textThe research leading to the results presented in this chapter has received funding from the Estonian Research Council (Institutional Research Grant IUT no. 2–17 on Spatial Population Mobility and Geographical Changes in Urban Regions); European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013) / ERC Grant Agreement no. 615159 (ERC Consolidator Grant DEPRIVEDHOODS, Socio-spatial Inequality, Deprived Neighbourhoods, and Neighbourhood Effects); and from the Marie Curie programme under the European Union’s Seventh Framework Programme (FP/2007-2013) / Career Integration Grant no. PCIG10-GA-2011-303728 (CIG Grant NBHCHOICE, Neighbourhood Choice, Neighbourhood Sorting, and Neighbourhood Effects).Growing inequalities in Europe, even in the most egalitarian countries, are a major challenge threatening the sustainability of urban communities and the competiveness of European cities. Surprisingly, though, there is a lack of systematic representative research on the spatial dimension of rising inequalities. This is filled by our book project Socio-Economic Segregation in European Capital Cities: East Meets West, with empirical evidence from Amsterdam, Athens, Budapest, London, Madrid, Milan, Oslo, Prague, Riga, Stockholm, Tallinn, Vienna and Vilnius. This introductory chapter outlines the background to this international comparative research and introduces a multi-factor approach to studying socio-economic segregation. The chapter focuses on four underlying universal structural factors: social inequalities, global city status, welfare regime and housing system. Based on these factors, we propose a hypothetical ranking segregation levels in the thirteen case study cities. As the conclusions of this show, the hypothetical ranking and the actual ranking of cities by segregation levels only match partly; the explanation for this can be sought in context-specific factors which will be discussed in-depth in each of the case study chapters
Molecular phylogeny and speciation patterns in host specific monogeneans (Cichlidogyrus, Dactylogyridae) parasitizing cichlid fishes (Cichliformes, Cichlidae) in Lake Tanganyika
No full textsponsorship: The authors are grateful to C. Sturmbauer (University of Graz, Austria), W. Salzburger (University of Basel, Switzerland), D. Muzumani Risasi (CRH-Uvira, DR Congo) for their precious help with cichlid collection and identification; M. Reichard and R. Blaz. ek (Czech Academy of Sciences, Czech Republic) for their help with fish collection, dissection and providing us with the photographs of cichlid species during the field trip; A. Meyer (University of Konstanz, Germany), G. Banyankimbona (University of Burundi), the Schreyen-Brichard family (Fishes of Burundi) and T. Veall and O. R. Mangwangwa (Rift Valley Tropicals, Zambia) for sample collection and fish identification; P. Masilya Mulungula, T. Mulimbwa N'sibula, V. Lumami Kapepula, E. Bahane Byaragi, S. Kambale Mukeranya and F. Muterezi Bukinga (CRH-Uvira, DR Congo) for coorganising the field work and their scientific contribution on LT cichlids; S. Masova, V. Michalkova, E. R. ehulkova, I. Pr.ikrylova, L. Raisingerova, N. Kmentova, K. Civan. ova, E. Jirounkova, K. Koukalova, and M. Seifertova (Masaryk University, Brno, Czech Republic) for their help with fish dissection, parasite isolation and fixation and molecular laboratory analyses; and B. Egger, J. Rajkov and A. Anh-Thu Weber (University of Basel) for providing samples of Astatotilapia burtoni from Zambian systems. The first author thanks D. Ortiz Martinez (Masaryk University, Brno, Czech Republic) for stimulating discussions and constructive suggestions and criticisms related to phylogenetics. Finally, the authors would like to thank M. Gelnar for the continuous help he provided during this research. This research was funded by the Czech Science Foundation project no. P505/12/G112 -European Centre of Ichtyoparasitology (ECIP) and the Special Research Fund of Hasselt University (BOF20TT06, to M.P.M.V.). Fieldwork was partly supported by the Research Foundation-Flanders (FWO-Vlaanderen) (travel grants V.4.096.10.N.01 and K.2.032.08.N.01 to M.P.M.V., Research Programme G.0553.10) and a travel grant from the King Leopold III Fund for Nature Conservation and Exploration (to M.P. M.V.). Sampling was performed in accordance with mission statements no. 013/MNRST/CRHU/2010, 022/MINEURS/CRH-U/2013 and 031/MINRST/CRH-U/2016 from the Ministere de la Recherche Scientifique et Technologique-CRH-Uvira. The funders had no role in study design, data collection and analyses, decision to publish, or preparation of the manuscript. (Czech Science Foundation|P505/12/G112, Hasselt University|BOF20TT06, Research Foundation-Flanders (FWO-Vlaanderen)|V.4.096.10.N.01, Research Foundation-Flanders (FWO-Vlaanderen)|K.2.032.08.N.01, Research Foundation-Flanders (FWO-Vlaanderen)|G.0553.10, King Leopold III Fund for Nature Conservation and Exploration)status: Publishe
The use of equivalent annual cost for cost benefit analyses in flood risk reduction strategies
No full textIn many parts of the world, flooding is a big risk. There are numerous strategies to reduce flood risk. The amount of flood risk reduction strategies grows exponentially with the amount of possible measures that can be implemented and possible timings when measures can be implemented. In this paper, the use of a financial method called “equivalent annual cost” (EAC) is assessed to reduce that number of strategies and evaluate cost-optimal strategies. The use of EAC allows the comparison between short-term and long-term measures by expressing them into an annual interest weighted expected expenditure. As soon as a measure has to be implemented (i.e. the annual risk becomes too large or the safety standards are exceeded), the EAC for all combinations of measures is determined and the combination is implemented with the lowest EAC. This almost leads to cost-optimal flood risk reduction strategies that, by manual optimization, can be improved further. A case study has also been performed in the Hollandsche IJssel which proved the use of EAC. Here it has led to cost-optimal flood risk reduction strategies. The method is tested in one case and it is recommended to apply and test it in other cases as well.Integral Design & ManagementHydraulic Structures and Flood Ris
UvA-DARE (Digital Academic Repository) European Journal of Industrial Relations Netherlands Wage and workforce adjustments in the economic crisis in Germany and the Wage and workforce adjustments in the economic crisis in Germany and the Netherlands Maart
No full textWage and workforce adjustments in the economic crisis in Germany and the Netherlands Tijdens, K.G.; van Klaveren, M.; Bispinck, R.; Dribbusch, H.; Öz, F. General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. Maarten van Klaveren Universiteit van Amsterdam, The Netherlands Reinhard Bispinck Wirtschafts-und Sozialwissenschaftliches Institut (WSI), Düsseldorf, Germany Heiner Dribbusch Wirtschafts-und Sozialwissenschaftliches Institut (WSI), Düsseldorf, Germany Fikret Öz Institut Arbeit und Technik, Gelsenkirchen, Germany Abstract This study uses data from a continuous employee web-survey to investigate the trade-off between wage and workforce adjustments and the role of industrial relations in firm-level responses to the economic crisis in Germany and the Netherlands. Workforce adjustments seemed to be a continuous organizational strategy, but wage adjustments were less often reported. We found no large-scale evidence of wage concessions being traded-off for job protection in the two countries. Collective bargaining ensured that wage-setting was more robust than employment protection: employees covered by collective agreements reported workforce adjustments more often than wage adjustments. Low-educated and low-wage employees reported basic wage reductions more often: the economic crisis increased wage inequality. Labour hoarding was reported predominantly by young, male employees with a permanent, full-time contract
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
No full textThe QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could indicate the presence of the potentially lethal mendelian long-QT syndrome (LQTS). Using a genome-wide association and replication study in up to 100,000 individuals, we identified 35 common variant loci associated with QT interval that collectively explain ∼8-10% of QT-interval variation and highlight the importance of calcium regulation in myocardial repolarization. Rare variant analysis of 6 new QT interval-associated loci in 298 unrelated probands with LQTS identified coding variants not found in controls but of uncertain causality and therefore requiring validation. Several newly identified loci encode proteins that physically interact with other recognized repolarization proteins. Our integration of common variant association, expression and orthogonal protein-protein interaction screens provides new insights into cardiac electrophysiology and identifies new candidate genes for ventricular arrhythmias, LQTS and SCD
Torque spectroscopy for the study of rotary motion in biological systems
No full textAccepted Author ManuscriptBN/Nynke Dekker La
Prognostic factors of functional outcome in acute ischemic stroke
No full textTrombolyse is een behandeling waarbij een stolsel in een bloedvat wordt opgelost door het gebruik van anti-bloedstollingsmiddelen. Irene Miedema deed onderzoek naar veiligheidsaspecten van trombolyse.
Door de ontwikkeling van trombolyse is de zorg aan patiënten met een acuut herseninfarct de afgelopen decennia sterk verbeterd. De behandeling is echter alleen voor een selecte groep beschikbaar en is niet zonder risico’s.
Miedema bestudeerde een groep van ruim 700 patiënten. Zij vond dat trombolyse na drie maanden geen verbeterde klinische uitkomst gaf, wanneer deze patiënten voor het herseninfarct een bepaald soort antidepressivum (SSRI), een cholesterolverlagend middel (statine) of urinezuur gebruikten. De promovenda constateert dat dat ook het geval was wanneer de bloedsuikerspiegel bij aanvang van de behandeling te hoog was. Tot slot ontdekte ze dat behandeling met een vitamine K antagonist (een anti-bloedstollingsmiddel) bij patiënten met een normale of licht verhoogde bloedstollingswaarde leidde tot een verhoogd risico op het ontwikkelen van een hersenbloeding.
Omdat trombolyse nog steeds de eerste keus behandeling is, is het voor de veiligheid van patiënten extra van belang dat artsen daarvoor de juiste patiënten selecteren. Deze uitkomsten kunnen daarbij helpen.
In the last decades, the development of revascularisation therapy with intravenous recombinant tissue plasminogen antigen (tPA) has greatly improved the outcome of acute ischemic stroke patients, but this therapy is only available for a selected group of patients and has safety concerns. In this thesis several possible neuroprotective agents in acute ischemic stroke and some safety aspects of tPA-treatment are discussed. In a cohort of patients with acute ischemic stroke treated with intravenous tPA no improvement of functional outcome at 3 months after the event was found in patients using selective serotonin re-uptake inhibitor (SSRI) or statin. Serum uric acid levels were also unrelated to improvement outcomes in patients with acute ischemic stroke. Concerning safety, for all stroke subtypes, hyperglycemia during admission was associated with a poor functional outcome in patients treated with tPA. Using vitamin-K-antagonist in patients with normal or slightly elevated International Normalized Ratio (INR) who are treated with tPA, is associated with the risk of symptomatic intracranial hemorrhage (SICH), but not with the actual functional outcome at 3 months after ischemic stroke. In conclusion, the studies in this thesis do not support a neuroprotective effect of SSRIs, statins and serum uric acid levels in patients with acute ischemic stroke. Treatment with tPA is still the most effective therapy for acute ischemic stroke and selection of patients to reduce treatment risks is important. Use of vitamin-K-antagonist with elevated INR and admission hyperglycemia are associated with the occurrence of SICH and poor functional outcome respectively.
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