360 research outputs found

    Modifikasi Desain Struktur Jembatan Ratna dengan Menggunakan Struktur Baja Komposit Jalan Ratna – Darmokali Kota Surabaya, Jawa Timur

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    Jembatan Ratna terletak di Kota Surabaya yang melewati Sungai Kalimas yang masuk dalam Proyek Pemerintah Kota Surabaya dengan dana CSR dari PT Bumiputera. Jembatan ini memiliki panjang 29,4 m dengan lebar 19,40 m didesain dengan 5 lajur kendaraan dan pedestrian di sisi kanan dan kiri jembatan. Jembatan ini melintasi sungai Kalimas yang menghubungkan Jalan Ratna dengan Jalan Bengawan Surabaya dengan kedalaman ± 2,97 meter dari mukai air sungai terhadap elevasi dasar sungai. Jembatan ini awalnya menggunakan balok pratekan pada struktur girder. Penulis memodifikasi desain girder jembatan menjadi balok komposit baja pada struktur girder. Jembatan Ratna digunakan sebagai objek tugas akhir untuk memodifikasi desain struktur jembatan meliputi bangunan atas meliputi: pelat lantai dan bangunan pengaman lainya menggunakan SNI 1726-2016. Perencanaan sambungan mengacu pada AISC-LRFD. Perencanaan bangunan bawah meliputi : pilar, abutment, pondasi, tiang pancang, dan elastomer mengacu pada RSNI 2T-12-2004 serta SNI 2833:2013 Standar Perencaanaan Ketahanan Gempa untuk Jembatan. Jembatan Ratna didesain ulang menggunakan struktur baja komposit dengan bentang jembatan 29,4 meter. Jembatan didesain menggunakan profil gelagar memanjang W 900 x 300 x 16 x 28 dan profil diafragma W 300 x 300 x 10 x 15. Ditengah jembatan juga didesain pilar menggunakan beton yang kuat terhadap aliran air dan benda hanyut aliran sungai. Pada bagian pondasi juga didesain menggunakan spun pile diameter 500 mm sebanyak 16 buah pada abutment dan 20 buah pada pilar. Dari perhitungan desain yang dimodifikasi dari struktur Jembatan Ratna diperoleh bentuk tiang sandaran dengan dimensi 200mm x 200mm dengan tinggi 1,25 m, pelat lantai kendaraan dengan tebal 250 mm. Jembatan ini juga akan dipasang elastomer berdimensi 300 x 500 x 73 mm. ================================================================================================================== Ratna Bridge is located in Surabaya City passing through Kalimas River which is included in Surabaya City Government Project with CSR fund from PT Bumiputera. This Bridge has 29,4 meters of length, and 19,40 meters of width designed with 5 lanes of vehicles and pedestrian on the right and left side of the bridge. This bridge across Kalimas River connects Ratna Street with Bengawan Street Surabaya with ± 2.97 meters above the river water level to the riverbed. This bridge initially used prestressed beams on the girder structure. The author modified the bridge girder design to steel composite beam in the girder structure. Ratna Bridge is used as the final task object to modify the design of the bridge structure covering the upper building includes: floor plates and other security buildings using SNI 1726-2016. Connection planning refers to AISC-LRFD. Bottom structure planning includes : pillar,abutment,fondation,pile, and elastomers are refer to RSNI 2T-12-2004 and SNI 2833:2013 "Standar Perencanan Ketahanan Gempa untuk Jembatan" (Earthquake Resilience Planning Standards for Bridges). Ratna Bridge is being redesigned using composite stell structure with bridge width of 29,4 meters. Bridge Class being redesigned using extend girder profile of W 900 x 300 x 16 x 28 and diaphragm W 300 x 300 x 10 x 15. In the middle of the bridge also designed using concrete pillar which could hold the waterflow and float off objects. On the foundation part also designed using spun pile with 500mm of diameters,16 piles for abutment and 20 piles for pillars. From the calculation of the modified stucture of Ratna Bridge,the obtained shape of the support pole is 200mm x 200mm with 1,25 m of height, vehicles floor plate with 250mm of thickness. Elastomer with dimension of 300 x 400 x 73 mm will also installed on this bridge

    Didaktika: Jurnal Pendidikan Vol.1 No.1

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    Jurnal pendidikan DIDAKTIKA yang merupakan wahana Direktorat Pembinaan Pendidikan dan Pelatihan, Direktorat Jenderal Peningkatan Mutu Pendidik dan Tenaga Kependidikan sebagai bentuk aktivitas pembinaanya selama ini terhadap para Widyaiswara LPMP, PPPPTK dan Tenaga Fungsional BPPLSP. Jurnal Pendidikan DIDAKTIKA diharapkan dapat menjadi wahana bagi perkembangan dan kemajuan dunia pendidikan di Indonesia. Jurnal ini memuat judul artikel sebagai berikut: 1. Peningkatan Komunikasi Siswa Dalam Pembelajaran Ekonomi Dengan Pendekatan PAKEM oleh Sutriari Astati 2. Penyusunan dan Implementasi Rencana Pengembangan Sekolah Dalam Meningkatan Mutu Pendidikan Pada SMP Negeri di Bandar Lampung oleh Ernawati 3. Pembuatan Filter Microstrip Band Pass 2.4 Ghz Dengan Struktur Satu Lapis oleh oleh Sugiono 4. Pengaruh Pengawetan Hipofisa Dari Limbah Kegiatan Fillet Ikan Patin Terhadap Pemijahan Ikan Patin (Pangasius Sutchi) oleh Gusrina 5. Persepsi Guru Pada CD Rona Demokrasi dan Pengaruhnya Terhadap Kualitas Pembelajaran IPS di SMP oleh Suparlan dan Endang Ekonomi 6. Peningkatan Aktivitas Siswa Dalam Pembelajaran Melalui Pendekatan Kontekstual Tipe Recopry oleh Rasoki Lubis 7. Struktur dan Kompetesi Soal Ujian Nasional Serta Relevansinya Dengan Tuntuan Standar Kompetensi Lulusan oleh Ai Sofiyanti 8. Optimalisasi Pengolahan Limbah Pelarutan Printed Circuit Board (PCB) di PPPG Teknologi Malang dengan Cara Elektrolisis Menggunakan Sel Surya oleh Agung Suprihatin dan Ratna Ediati 9. Pembelajaran Apresiasi Sastra Membaca Cerpen Melalui Pendekatan Interaksi Dinamis di Kelas X-5 SMA Negeri 28 Jakarta oleh Orsid

    First record of Celaenorrhinus ratna daphne Evans,1949 from Himachal Pradesh and its first photographic record from the Western Himalayas (Lepidoptera: Hesperiidae, Pyrginae)

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    The daphne subspecies of Celaenorrhinus ratna Fruhstorfer, [1908] reported first by Evans (1949) from Uttarakhand and has not been reported in the past from the neighbor state Himachal Pradesh. In July 2017, Author recorded and photographed about eight specimens of Celaenorrhinus ratna daphne Evans, 1949 for the first time near McLeodganj town of Himachal Pradesh.La subespecie daphne de Celaenorrhinus ratna Fruhstorfer, [1908] citada por primera vez por Evans (1949) de Uttarakhand y no ha sido citada en el pasado del estado vecino Himachal Pradesh. En julio de 2017, el autor registró y fotografió unos ocho ejemplares de Celaenorrhinus ratna daphne Evans, 1949 por primera vez cerca de la ciudad de McLeodganj de Himachal Pradesh

    Critical Analysis of Rasa Ratna Samuchhaya with Respect to its Applied Aspects on Ayurvedic Pharmaceutical Process

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    Objective:Rasa Ratna Samuchaya is one of the pioneer literature of Rasa Shastra, written during 13th Cen. AD. Acharya Rasa Vagbhat has written this book with utmost care to the practical and applied aspects of Ayurvedic pharmaceutics in the ancient language. The objective of this review article is to explore and critically analyze the trend of development and applied aspects of Ayurvedic pharmaceutics in contemporary language that may help the academicians and Ayurveda industries.Data Sources:The current manuscript is prepared collecting literature from the book Rasa Ratna Samuchhaya, different commentary on it by eminent scholars and from published papers in different journals.Review Methods:The facts and philosophies mentioned in the same book and different commentaries are thoroughly analyzed, reviewed with respect to historical edges, traditional values, and applied aspects and tried to present systematically and affirmatively.Conclusion:The concerned part of the book reviewed is the 11 chapters, of the first part of the book, where the author has tried to describe; the definition of technical terminologies, designing and uses of different types of tools and devices, identification and collection of materials, systematic pharmaceutical processings, and therapeutic uses as well, in concern with metals/minerals. This book acknowledges all the fundamental principles of Rasa Shastra systematically with approaching its future course of development. This manuscript contains all the rational and time needed descriptions with the elimination of impractical and outdated hypothetical materials (carry forwarded by many previous era authors), having no more utility, with the use of available materials and contemporary intellectuals

    CHARACTERIZATION K3PO4/NaZSM-5 USING XRD AND FTIR AS A CATALYST TO PRODUCE BIODIESEL

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    Synthesis of NaZSM-5 and impregnation of K3PO4 catalyst with concentration 5, 10, and 15 wt.% on the resulting NaZSM-5 as a catalyst to produce biodiesel have been done in this study. This study is an experimental study, the research stages include the synthesis and characterization NaZSM-5 and K3PO4/NaZSM-5. Characterization by X-Ray Diffraction (XRD) was conducted to determine the X-ray diffraction patterns and the percentage crystallinity of the samples. X-ray diffraction pattern of the resulting sample showed the emergence of diffraction peaks with high intensity at 2θ = 7.8; 8.8; 23.0; 23.2, and 24.3° are specifically indexed to the structure of the MFI topology. The percentage crystallinity of the sample becomes smaller with increasing number of K3PO4 impregnated on NaZSM-5 synthesis. Characterization of the samples by Fourier Transform Infra Red (FTIR) aims to determine the type of functional groups present in a compound. FTIR spectra of samples NZ, NZK5, NZK10 and NZK15 have absorption bands in the region 1220 and 547 cm-1 which shows the absorption characteristics of vibration T - O - T on NaZSM-5 type zeolite which distinguish the other and sensitive to changes in structure. The results of characterization using XRD and FTIR showed that the structure of NaZSM-5 remained unchange after impregnated with K3PO4

    High resolution profiling of EGFR mutations in glioblastoma patients using an ultrasensitive digital PCR approach

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    Glioblastoma Multiforme (GBM) is the most aggressive type of adult brain cancer. The average survival time after GBM diagnosis is 14.6 months even with current tri-modality therapy. The Epidermal Growth Factor Receptor (EGFR) is amplified in 57% of GBM. Mutations in EGFR such as EGFR variant III, A289V, and R108K lead to more aggressive tumors, and diminished survival. We are in dire need of a molecular assay that rapidly profiles these alterations in EGFR since other assays currently available clinically, like Next Generation Sequencing, may take up to 4 weeks due to the batching of samples in current workflows. Our lab has established a very sensitive and novel digital Polymerase Chain Reaction (dPCR) assay that detects EGFRvIII in patient tumors within 24 hours of resection. This dPCR assay utilizes RNA extracted from microgram quantities of resected tumor from GBM patients, which is then converted to complementary DNA (cDNA). cDNA is then pre-amplified and subjected to the dPCR assay using specific primers and probes for EGFRvIII and EGFR WT. The assay is multiplexed with an internal reference control, RNaseP. The same starting material can be used to detect the presence or absence of two other mutations, R108K and A289V, with exquisite sensitivity and specificity. We have utilized this assay and tested the platform on patient derived organoids and patient tumor samples. We have also validated this assay on exosomal RNA extracted from media used for culturing U87 WT and U87 vIII cell lines, as well as patient-derived glioma stem cell lines like NS039 and T4213. This assay allows for rapid and ultrasensitive detection of EGFRvIII, EGFRWT, R108K, and A289V mutations in patient tumors and patient derived organoids. The workflow for this assay allows results within 24 hours of tumor resection, which facilitates early initiation of novel investigational therapeutic agents. It is possible that molecular characterization of tumor tissue, biofluids, microvesicles, platelets, and cfRNA would help to elucidate genomic variations that occur during disease recurrence. In the future, we plan to test this assay on RNA extracted from various microvesicles and platelets derived from blood to facilitate non-invasive tumor characterization and usefully complement conventional follow-up and imaging methods.This poster was presented at the first annual Celebration of Undergraduate Research and Creative Activity while the author was an undergraduate student at Rutgers University-Camden

    TA : Pembuatan Film Naratif Animasi 2D Berjudul "The Postman Story" (Animasi Karakter 2D dan Konsep Cerita)

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    Animation generally only use one technique just like animation with 2D or 3D techniques. Animation in Indonesia is quite rare that using a combination of 2D and 3D techniques. This animation tries to apply these techniques. The appearance glance looks like a 2D animation but actually the characters created with 2D techniques while environment made with 3D techniques. 2D and 3D animation has its own advantages and disadvantages. 2D animation has always come up with a simple form and color while 3D animations always look realistic that match the real shape. But both the animation also has shortcomings. Movements that are too rigid in 2D animation and the hassle of making a character or a complex environment in 3D animation. But these shortcomings can cover each other when both techniques are combined. In addition, by combining these techniques can produce a different animation. The process of making the animation is done separately because the film is done in groups consisting of two people. Pre-production and production process that includes the development of idea an concept, making treatment, storyboard, character design and 2D character animation done by the 2nd author (Ratna Indah S.). While the post-production and manufacturing processes environtment with 3D techniques performed by 1st author (Adinda Miftania). This animation uses a variety of software from the pre-production to post production. This final report is expected to be role model for young animators, both technically, and moral concepts contained therein

    Ekstrak Air J amur Ling Zhi (Ganoderma lucidum (Leysser) Karsten) Meningkatkan Persentase Sel Limfosit T CD8+ Relatif pada Tikus yang Dipejani Doxorubicin

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    Cancer therapy using chemotherapeutic agents associated with many adversed side effects, including immunosupressant. The use of immunostimulator together with chemotherapeutic agent (co-chemotherapy) can be the alternative method to solve that problem. Ganoderma lucidum (Ling Zhi) has been reported to have immunostimulatory activity. The aim of this research was to evaluate the immunostimulatory activity of water extract of G. Zucidum by determining the relative CD8+ T lymphocyte cell percentage in rats induced by doxorubicin. Extraction of plant material was carried out by infusion method. Sprague Dawley female rats were divided into six groups, they were doxorubicin as control, commercial product as comparing control, 100 mg/kgBW and 450 mg/kgBW extract treatment, extract control, and without treatment control. Relative CD8+ T lymphocyte cell percentages of blood samples were obtained by flow cytometry by using Multiset program. The data were analyzed statistically using paired sample t test and one way ANOVA continued by Post Hoc test. The result showed that the water extract of G. lucidum increased the relative CD8+ T lymphocyte cell percentage in rats induced by doxorubicin. The water extract of G. lucidum is promising to be developed as co-chemotherapy immunostimulatory agent.Pengobatan kanker dengan agen kemoterapi sering menimbulkan berbagai macam efek samping yang merugikan, termasuk imunosupresi. Penggunaan imunostimulan bersama dengan agen kemoterapi (ko-kemoterapi) dapat menjadi alternatif untuk mengatasinya. Ganoderma lucidum (jamur Ling Zhi) dilaporkan menunjukkan aktivitas imunostimulan. Penelitian ini bertujuan untuk mengevaluasi aktivitas imunostimulan ekstrak air G. lucidum dengan menentukan persentase sel limfosit T CD8+ relatif pada hewan uji yang dipejani doxorubicin. Ekstraksi bahan tanaman dilakukan dengan metode infusa. Tikus betina galur Sprague Dawley dibagi dalam 6 kelompok, yaitu kelompok kontrol doxorubicin, kontrol pembanding produk komersil, perlakuan ekstrak dosis 100 mg/kgBB dan 450 mg/kgBB, kontrol ekstrak, dan kontrol tanpa perlakuan. Persentase sel limfosit T CD8+ relatif dari sampel darah diukur dengan flow cytometry menggunakan program Multiset. Data dianalisis secara statistik dengan t test dan one way ANOVA, dilanjutkan Post Hoc test. Hasil penelitian menunjukkan bahwa ekstrak air G. lucidum mampu meningkatkan persentase sel limfosit T CD8+ relatif pada tikus yang dipejani doxorubicin. Ekstrak air G. lucidum menjanjikan untuk dikembangkan sebagai agen imunostimulan ko-kemoterapi

    Pengelolaan Hotel Syariah Menurut Fatwa DSN-MUI Nomor 108 Tahun 2016 Tentang Pedoman Penyelenggaraan Pariwisata Berdasarkan Prinsip Syariah (Studi Kasus di Hotel Ratna Syariah Kota Probolinggo)

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    This study examines about how the operation of the Ratna Syariah Hotel from its product, service, and management aspects according to the DSN-MUI fatwa and the principles of Sharia Economic Law which include the principles of tauhid, the principle of justice, the principle of ta'awun (help), the principle of khilafah, and the principle of maslahah. This research is limited to the following problems: (1) How are sharia-based products, services, and management carried out by Hotel Ratna Syariah in the City of Probolinggo according to the DSN-MUI fatwa on Guidelines for Implementing Sharia-Based Tourism Principles? (2) How are sharia-based products, services and management implemented by Hotel Ratna Syariah in the City of Probolinggo according to the Principles of Sharia Economic Law? This type of research is field research, namely research activities conducted at Ratna Syariah Hotel located in the city of Probolinggo. To understand and analyze the object under study, several approaches are used as follows: (1) Legislative approach, meaning that the operational implementation of Sharia Ratna Hotels in the city of Probolinggo will be analyzed intensively, deeply, in detail and comprehensively based on the legal regulations governing this matter is the DSN-MUI fatwa and also Islamic sharia principles. The data collection technique is done by interview, observation, and documentation.The results of this study are: (1) In general, the products offered are in accordance with DSN-MUI fatwa Number 108 of the third section which contains general principles of sharia tourism administration, and also the fifth section which contains provisions related to sharia-based hotel management which includes provisions regarding products in sharia hotels; the services provided are in accordance with the fifth part of DSN-MUI fatwa, which contains the provisions related to sharia-based hotel management which include provisions regarding products and services, except the seventh point which regulates that sharia hotels must use the services of Islamic Financial Institutions in performing services ( financial transactions); and the management carried out by the Hotel Ratna Syariah is in accordance with the third part of the DSN-MUI fatwa, which contains the general principles of implementing sharia tourism; the fourth part which contains the contract provisions that must be used in the implementation of the sharia tourism business; and the fifth part which contains provisions related to sharia-based hotel management which includes provisions regarding products, services, and operations, except point six in this section; (2) the operationalization of products, services, and management of Sharia Ratna according to the results of the research of the author in accordance with the principles in Sharia Economic Law which includes the principles of tauhid, the principle of justice, the principle of ta'awun (help), the principle of khilafah, and principles maslahah. Keywords: Sharia Hotels, Fatwas, DSN-MUI, Sharia Principles, Sharia Economic Law
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