740 research outputs found
Histoire et théorie de la justification juridique : approche comparée
No full textMathilde Cohen, chargée de recherche au CNRS Ce séminaire a constitué une introduction à l’histoire et à la théorie de la justification juridique et, notamment, à la notion spécifiquement juridique de « motivation des décisions ». Nous poursuivrons cette problématique en 2010-2011 en nous concentrant plus particulièrement sur le cas des Cours constitutionnelles, dans le cadre d’un séminaire enseigné conjointement avec Pasquale Pasquino, intitulé : « Les Cours constitutionnelles et la raison p..
Les Cours constitutionnelles et la raison publique. La motivation des décisions de justice
No full textMathilde Cohen, chargée de recherche au CNRSPasquale Pasquino, directeur de recherche au CNRS Ce séminaire a porté à la fois sur les débats contemporains concernant le libéralisme politique et sur les idées de constitutionnalisme et de démocratie constitutionnelle, à travers l’étude de la notion tant controversée de « raison publique ». Dans son Libéralisme politique, John Rawls déclare que la Cour suprême américaine constitue le parangon de la raison publique, entendue au sens de justificati..
Book review: making milk: the past, present and future of our primary food edited by Mathilde Cohen and Yoriko Otomo
No full textIn Making Milk: The Past, Present and Future of Our Primary Food, editors Mathilde Cohen and Yoriko Otomo assemble a provocative collection of strong interdisciplinary scholarship to explore milk’s material, affective, historical, semantic, symbolic and economic relations, writes Jeanne Firth
Author's gift inscription, in The heather on fire; a tale of the Highland clearances
No full textThis edition includes an author's gift inscription, "To Mrs John Dillon with sincere esteem Mathilde Blind".Blind, Mathilde, 1841-189
Gender and pedagogics - Mathilde Vaerting, professor of educational science (Jena, 1923-1933)
No full textDer Aufsatz skizziert Leben und Karriere von Mathilde Vaerting (1884-1977), der ersten Professorin für Erziehungswissenschaft in Deutschland, Jena 1923-1933. Ihr Hauptwerk „Neubegründung der Psychologie von Mann und Weib", 1921ff., wird unter Aspekten der Forschungslogik analysiert und auf Konsequenzen für die Erziehungswissenschaft befragt. Ihre Forderung nach Gleichberechtigung und Abwehr jeglicher Herrschaft werden vor dem Hintergrund heutiger feministischer Forderungen diskutiert. Im Anschluß an die Betrachtung der zeitgenössischen Rezeption Mathilde Vaertings wird die Frage aufgeworfen, inwieweit ihr Leben und ihre Karriere die Stellung der Frau in der Wissenschaft während der zwanziger Jahre (und auch später?) spiegeln. (DIPF/Orig.)The author outlines the biography and career of Mathilde Vaerting (1884-1977), the first woman to hold a chair in educational science in Germany. Her major work - Neubegründung der Psychologie von Mannund Weib (1921 fol.) - is analyzed from a methodological point of view and with respect to its implications for educational research. Vaerting\u27s demands for equal rights for women and her rejection of any kind of domination are discussed within the framework of present feminist positions. After having studied how contemporaries reacted to Mathilde Vaerting\u27s writings, the author raises the question of whether Vaerting\u27s life and career reflect the Status of women in science during the 1920s (and later on?). (DIPF/Orig.
Mathilde Blind
No full textThe first titles in the Eminent Women Series published in 1883 by W. H. Allen included studies of Emily Bronte and George Sand (Margaret Fuller, Maria Edgeworth, Elizabeth Fry, and Harriet Martineau would be in the next wave) as well as Mathilde Blind\u27s pioneering, sensitive, uneven and sympathetically feminist exposition of George Eliot\u27s life and art. Blind herself deserves a full-length study, and at particular points her own life and works touch those of George Eliot. Born Mathilde Cohen in Mannheim in 1841, she took her stepfather\u27s name when her mother remarried. Dr. Karl Blind was an ardent republican in Baden, was imprisoned, freed, then exiled himself, first to Belgium then to England, the family settling in St John\u27s Wood a couple of years after the European year of Revolutions in 1848. Richard Gamett, in the Memoir prefixed to the Poetical Works of Mathilde Blind (1900) refers to her unpublished autobiographical writings in which he notes her strong attachment to another girl at her school, her love of music and dancing (exemplified in her novel Tarantella, 1885) and her embracing of Christianity in her girlhood as \u27this profoundly personal religion\u27. Her early poetic predilections are seen in her reactions to Swiss scenery, where she describes \u27high white clouds changing chameleon-like as the sun and wind touched their ethereal substance. Sometimes they stood on tiptoe on the top of a mountain peak like columbines balancing themselves on the shoulders of a giant\u27. This was in 1859, ten years after George Eliot\u27s Geneva experience, and just as the emergent novelist was to rehearse her wittily ironic observations of people met in a pension, so Blind rehearsed her natural powers of observation on the elevating and consoling effects of nature. She read avidly, her German inheritance ensuring her admiration of Goethe, while she wrote an ode to celebrate the Schiller centenary in Bradford (1859), and shared with Lewes a fascination for Robespierre, writing a tragedy about him which was praised by Louis Blanc. Blind - dazzlingly beautiful when young - admired Mazzini, but found Gariba1di (c. 1864) lacking in personal magnetism though inspiring nonetheless. She sought the company of famous men: Mazzini prescribed a course of reading for her (as Scott Fitzgerald was to do for Sheila Graham in the 1930s) but, although she hung \u27with my whole soul upon his every word\u27, from the mid-l 860s onwards she was concerned with raising the status of women, passionately interested in their education, which she regarded essential if they were to achieve a proper equality with men. She was an enthusiastic admirer of George Eliot, had a more temperate admiration of George Sand, was bowled over by \u27Aurora Leigh\u27, was influenced by Carlyle, and more profoundly by Henry Thomas Buckle (1821-62), author of A History of Civilisation in England, only two volumes of which had appeared before his premature death. He adopted a scientific basis for historical investigation and was much admired by Darwin: Blind obviously found this congenial, so much so that one of her later (and greater) poems is called \u27The Ascent of Man\u27 and is distinctly Darwinian in its emphasis. In 1866 her brother Ferdinand committed suicide following his failed attempt to assassinate the great German statesman Bismarck, and annual tribute was paid to him by Blind and many sympathizers. In 1867 she published her first poems under the pseudonym of Claude Lake, and soon began to see herself as a lecturer: interestingly Trollope\u27s American friend Kate Field embarked on just that career with some success on both sides of the Atlantic. In 1869 Blind lectured on Shelley at St George\u27s Hall (her beauty winning, her accent difficult), and as a result met John Chapman, her lecture being reproduced in his Westminster Review (July 1870), the periodical George Eliot had edited for Chapman in the early 1850s. Thereafter she travelled much, became interested in another cult of the time, spiritualism, and, in 1873, published her translation of Strauss\u27s final work, The Old Faith and. the New. Visits to Scotland stimulated her sense of history and her poetic impulse: she was to write movingly about the clearances of the Highlands in \u27The Heather on Fire\u27 (1886), observing of the glens and the desolated villages that \u27it was but yesterday that they were inhabited by a brave, moral, and industrious peasantry, full of poetic instincts and ardent patriotism, ruthlessly expelled their native land to make way for sporting grounds rented by merchant princes and American millionaires\u27 . Bronchial, financially insecure, suffering from bouts of depression, she contributed two biographies to the Eminent Women Series. The first, on Eliot, cost her much labour, even anguish. When she had finished it, she feelingly recorded: \u27It was a lovely afternoon. I was too tired to walk, and sat down on a bench in a little garden in front of the house, drinking in the air, the hum of the insects, the colour of flowers and leaves, the glory of the sky\u27. The second, Madame Roland (1886) had to be cut down by a third (\u27So Madame Roland was decapitated for the second time\u27, observes Gamett); she produced a series of aphorisms from Goethe for Fraser\u27s Magazine, wrote a preface to a selection from Byron for the Camelot series (1886), and lived for some time with the Madox Browns in Manchester and London. In 1892 she inherited a fortune from her brother Max Cohen, journeyed to Rome and Egypt, and wrote a number of poems before she went into a decline: she spent some time in the company of the Regius Professor of Medicine at Cambridge, Dr. Clifford Allbutt (friend of Eliot and Lewes, thought by some to have provided the germ of Lydgate) and, wishing to benefit women\u27s education practically, left the greater part of her estate to Newnham College, Cambridge, when she died in 1896. A fine monument was erected to her memory in Finchley Cemetery, where she was buried close to the grave of her friends the Madox Browns
Effi Briest, Mathilde Möhring. The Development of Theodor Fontane's Female Characters on the Background of Women Emancipation.
No full textTheodore Fontane is best known as the author of numerous women's novels, which he wrote in the last ten years of his life. This diploma thesis deals with the topic of women's emancipation on the basis of textual analysis of two latter novels by Theodore Fontane - Effi Briest and Mathilde Möhring. In the first part, it characterizes the topic of the period women's emancipation and puts the author's biography into context. In the second part, it creates the picture of position of the main women characters. The last part describes the personal development of the women characters, on the basis of which I determine how much the women's emancipation reflects in the author's work and what is his attitude towards it. This thesis deals with the interpretation of the author's intent to illustrate the creation of an advanced character like Mathilde Möhring. Key words: Theodore Fontane, women's emancipation, Effi Briest, Mathilde Möhring, development of women's characters, women's novels, interpretation, author's intent, counterpoin
Effi Briest, Mathilde Möhring. Vývoj postavy žen na pozadí dobové emancipace ve stejnojmenných románech Theodora Fontana.
No full textTheodore Fontane is best known as the author of numerous women's novels, which he wrote in the last ten years of his life. This diploma thesis deals with the topic of women's emancipation on the basis of textual analysis of two latter novels by Theodore Fontane - Effi Briest and Mathilde Möhring. In the first part, it characterizes the topic of the period women's emancipation and puts the author's biography into context. In the second part, it creates the picture of position of the main women characters. The last part describes the personal development of the women characters, on the basis of which I determine how much the women's emancipation reflects in the author's work and what is his attitude towards it. This thesis deals with the interpretation of the author's intent to illustrate the creation of an advanced character like Mathilde Möhring. Key words: Theodore Fontane, women's emancipation, Effi Briest, Mathilde Möhring, development of women's characters, women's novels, interpretation, author's intent, counterpointTheodor Fontane je známý především jako autor četných ženských románů, které psal ve svém pokročilém věku. Tato práce zpracovává na základě analýzy textu téma ženské emancipace v jeho dvou pozdějších románech - Manželství Effi Briestové a Mathilda Möhringová. V první části charakterizuje téma dobové ženské emancipace a zasazuje autorovu biografii do kontextu. V druhé části utváří obraz pozice hlavních románových hrdinek. V poslední části je shrnut osobní vývoj ženských postav, na jejímž základě má být zodpovězena otázka, nakolik se ženská emancipace odráží v autorově díle a jaký je jeho postoj k ní. Práce se zároveň zabývá intepretací autorova záměru, který vytvořil postavu pokročilé Mathildy Möhringové, čímž dosáhl kontrapunktu k tomu, co doposud psal. Klíčová slova: Theodor Fontane, ženská emancipace, Effi Briest, Mathilde Möhring, vývoj ženských postav, interpretace, ženské romány, záměr autora, kontrapunktInstitute of Germanic StudiesÚstav germánských studiíFilozofická fakultaFaculty of Art
Gene Therapy for ALS—A Perspective
No full textInternational audienceAmyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease (MND) with no cure. Recent advances in gene therapy open a new perspective to treat this disorder-particularly for the characterized genetic forms. Gene therapy approaches, involving the delivery of antisense oligonucleotides into the central nervous system (CNS) are being tested in clinical trials for patients with mutations in SOD1 or C9orf72 genes. Viral vectors can be used to deliver therapeutic sequences to stably transduce motor neurons in the CNS. Vectors derived from adeno-associated virus (AAV), can efficiently target genes and have been tested in several pre-clinical settings with promising outcomes. Recently, the Food and Drug Administration (FDA) approved Zolgensma, an AAV-mediated treatment for another MND-the infant form of spinal muscular atrophy. Given the accelerated progress in gene therapy, it is potentially a promising avenue to develop an efficient and safe cure for ALS
Characterizing circumstellar disk around young stars
No full textThe circumstellar disks play a fundamental role in star and planet formation
process. Studies on circumstellar disks are generally carried on following two
viable approaches: "statistical" studies, where a large samples of sources
are measured to determine mean disk common properties, detailed study
on individual objects can shed the light on processes, like mass accretion,
central star irradiation or photoevaporation, that compete in defining the
shape and the lifetime of the disks, improving the theoretical models or,
hopefully, to directly catch a planet in the process of forming.
Although both approaches converge toward a general scenario, they are sensitive only the disk dust component, while recently there is a strong interest on the gas, since it constitutes most of the mass of the circumstellar disks, determining the dust dynamic and the settling process, and its dispersal timescales limit the formation of gas giant planets.
In this work I present a synoptic study carried on the young stellar object
TCha, belonging to the class of "transition" disks, peculiar systems where
very rapid evolution is ongoing. Such transitional disks are rare and, due to
their classification based on the shape of the spectral energy distribution, do
not represent an homogeneous class. For such reasons the characterization
of any further object is extremely important to understand if we are dealing
with a planetary system in formation.
On the other side, I carried on a systematic study on recent discovered diagnostic for the gaseous disk component. The fine structure infrared emission line of [Ne ii] at 12.8 m has been discovered in more than 70 object. This line is thought to be produced by X-ray irradiation of the warm protoplanetary disk atmospheres, however the observational correlation between [Ne ii]luminosities and measured X-ray luminosities shows a large scatter. Such spread limits the utility of this line as a probe of the gaseous phase of disks, as several authors have suggested pollution by outflows as a probable cause of the observed scatter. For the first time with this work it has been explored the possibility that the large variations in the observed [Ne ii] luminosity may be caused instead by different star-disk parameters
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