44 research outputs found
Common Sense and a Little Fire
No full textOver twenty years after its initial publication, Annelise Orleck's Common Sense and a Little Fire continues to resonate with its harrowing story of activism, labor, and women's history. Orleck traces the personal and public lives of four immigrant women activists who left a lasting imprint on American politics. Though they have rarely made more than cameo appearances in previous histories, Rose Schneiderman, Fannia Cohn, Clara Lemlich Shavelson, and Pauline Newman played important roles in the emergence of organized labor, the New Deal welfare state, adult education, and the modern women's movement. Orleck takes her four subjects from turbulent, turn-of-the-century Eastern Europe to the radical ferment of New York's Lower East Side and the gaslit tenements where young workers studied together. Orleck paints a compelling picture of housewives' food and rent protests, of grim conditions in the garment shops, of factory-floor friendships that laid the basis for a mass uprising of young women garment workers, and of the impassioned rallies working women organized for suffrage. Featuring a new preface by the author, this new edition reasserts itself as a pivotal text in twentieth-century labor history.</p
(IN) ACCESS TO ARTIFICIAL LIMBS: THE PATIENT’S PERSPECTIVE ACCORDING TO THE WAR AMPS OF CANADA
No full textFunding agencies, both public and private, do not adequately meet the needs of Canadian amputees. This often leaves amputees without access to appropriate prosthetic care due to outstanding balances that are to be paid out of pocket, or by charitable organizations. There are several factors that result in these inadequacies. As healthcare is a provincial responsibility in Canada, provinces and territories have the authority to create individual public regimes, each with their own weaknesses. In fact, there are a few provincial regimes which do not include prosthetic funding at all. Private healthcare is meant to offset the remaining balance; however, their lack of knowledge regarding amputation has resulted in the creation of policies with ambiguous language, limiting the funding available for prosthetic care. Attitudinal barriers and missed legislative opportunities further exacerbate the shortcomings of prosthetic funding provided by public and private funding agencies, requiring action.
Article PDF Link:https://jps.library.utoronto.ca/index.php/cpoj/article/view/35972/28331
How To Cite: Petlock A, DiMario K. (In) Access to artificial limbs: the patient’s perspective according to the WAR AMPS of Canada. Canadian Prosthetics & Orthotics Journal. 2021; Volume 4, Issue 2, No.13. https://doi.org/10.33137/cpoj.v4i2.35972
Corresponding Author: Annelise PetlockThe War Amps Advocacy Program/ 2827 Riverside Drive Ottawa, Ontario, Canada.E-Mail: [email protected] ID: https://orcid.org/0000-0002-7273-452
AS PRIMEIRAS-DAMAS DE ROMA: UMA NOVA ABORDAGEM HISTORIOGRÁFICA
No full textThe First Ladies of Rome is the first book by English author Annelise Freisenbruch, a PhD in Classical Antiquity from Cambridge University and an assistant researcher in the production of popular books and films about the ancient world. In his work Freisenbruch analyzes the importance of the first Roman ladies in the rise and construction of the Roman Empire.As Primeiras-damas de Roma é o primeiro livro da autora inglesa Annelise Freisenbruch, doutora em Antiguidade Clássica pela Universidade de Cambridge e pesquisadora assistente na produção de livros e filmes populares sobre o mundo antigo. Em sua obra, Freisenbruch analisa a importância das primeiras-damas romanas na ascensão e construção do Império Romano
Le personnel, le politique et un peu du reste : les filles, les grrrls et les perzines
No full textUsing her own zine story as a vehicle, the author relates the history of the riot grrrl subculture, describes the girl zine genre and its history, and examines zinester subculture and networking. She also explores zinesters’ motivation and discusses the purpose girl zines fill in female zinesters’ lives
Henri Temianka Correspondence; (bunzel)
No full textThis collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/1515/thumbnail.jp
Can “the people” be feminists? Analysing the fate of feminist justice claims in populist grassroots movements in the United States
No full textIn this article I examine the fate of feminist justice claims in the context ofgrassroots populist movements in the United States. By exploring populism onthe left—in neighbourhood community organising—and on the right—withinthe community organising among the Tea Party—I argue that a “politics ofauthenticity” is deployed in each movement with strikingly similar effects onthe development of feminist consciousness and justice claims in eachmovement. In left-wing community organising I find that feminist claims aresuppressed in order to preserve solidarity among grassroots actors and to beperceived by movement outsiders as patriotic. On the right I demonstrate howwomen-centric practices are generated through the strategic use of an identityI label “concerned motherhood”. For the Tea Party, women appear to have theability to identify as women for local action but this process seems to threatenboth feminism and democracy by women’s support for a politics of inequality.I conclude with a discussion about whether feminism and populism can bereconciled and the perils that confront feminist activists in the current upsurgeof populist movements around the globe
The Personal, Political, and a Little Bit of Everything Else: Girls, Grrrls and Perzines
No full textUsing her own zine story as a vehicle, the author relates the history of the riot grrrl subculture, describes the girl zine genre and its history, and examines zinester subculture and networking. She also explores zinesters’ motivation and discusses the purpose girl zines fill in female zinesters’ lives
Avaliação dos efeitos citotóxicos de cardenolídeos em células tumorais
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaOs cardenolídeos são metabólitos secundários encontrados na natureza e assim denominados em razão de sua ação inibitória na bomba de Na+/K+ (Na+/K+ATPase) e decorrentes efeitos sobre o músculo cardíaco. Por esta razão, cardenolídeos, tais como digoxina, digitoxina e ouabaína, são clinicamente utilizados para o tratamento da insuficiência cardíaca congestiva e algumas arritmias atriais. Nos últimos anos, vários estudos relataram a potencial atividade citotóxica, antitumoral e anticâncer de alguns cardenolídeos. Mundialmente, o câncer de pulmão é um dos principais responsáveis pela alta taxa de mortalidade atribuída ao câncer. O tratamento atual deste câncer depende do estágio do paciente e são utilizadas abordagens combinadas ou individuais, tais como excisão cirúrgica, radioterapia e quimioterapia. A taxa de sobrevivência dos pacientes, no entanto, não é elevada, tornando a busca por novos agentes no combate a este câncer uma necessidade. Neste trabalho, foi realizada uma triagem citotóxica, em células tumorais humanas A549, com 64 cardenolídeos e um dos compostos mais citotóxicos (CI50<100 nM) foi selecionado para investigação do seu mecanismo de ação, através de vários ensaios. Este composto, que se apresentou mais tóxico e mais seletivo para células tumorais foi o glucoevatromonosídeo e para a avaliação de seu mecanismo de ação uma série de ensaios foi realizada. Inicialmente, ele provocou o bloqueio do ciclo celular na fase G2/M, o que foi atribuído à diminuição da expressão da proteína ciclina B1, necessária para a progressão do ciclo celular. A indução de morte celular, por ele causada, não ocorreu por apoptose ou necrose, sendo provavelmente por autofagia, processo observado com a marcação de partículas acídicas, características deste tipo de morte celular. O envolvimento deste composto em vias de sinalização de morte celular foi constatado por alterações na expressão de proteínas das vias AKT, MAPK e NF-?B. Por fim, a atividade anti-ATPásica detectada não mostrou correlação da inibição desta enzima com a atividade citotóxica apresentada pelos compostos selecionados na triagem. A citotoxicidade promissora do glucoevatromonosídeo foi investigada e confirmada sua indução de morte celular independente de apoptose em células A549.Cardenolides are secondary metabolites found in nature and named after their known inhibitory action on the sodium pump (Na+/K+ATPase), and effect on the heart muscle. For this reason cardenolides as digoxin, digitoxin and ouabain are used in the treatment of congestive heart failure and atrial arrhythmias. In the past years, many were the reports on the citotoxic, antitumoral and anticancer activities of cardenolides. Lung cancer is one of the leading causes of death by cancer worldwide. Current treatment of lung cancer depends on the stage of the patient and both combined and individual approaches are used, such as surgery, radiotherapy and chemotherapy. However, the observed survival rate is not high, which stimulates the search for new agents for the treatment of this cancer. In the present work a cytotoxic screening with 64 cardenolides was performed and the most cytotoxic compound selected (CI50<100 nM) to further investigate its mechanism of action. The most cytotoxic and selective compound for cancer cell lines was glucoevatromonoside and to evaluate its mechanism of action a series of assays was carried out. Initially, this compound was able to block phase G2/M of cell cycle, which was attributed to the decrease in the expression of cyclin B1 protein, essential to the cell cycle progression. The investigation of the cytotoxic effect of this compound showed that the induced cell death was not apoptosis or necrosis mediated, and so might be through autophagy, as observed with the acridine orange marked acidic particles, a characteristic event of this type of cell death. Involvement of this compound in signaling pathways was verified through its ability to trigger alterations in the expression of AKT, MAPK and NF-?B proteins. The detected anti ATPase activity did not show correlation of the enzyme inhibition with the cytotoxic activity presented by the compounds selected in the screening. Hereby, the promising cytotoxic activity of glucoevatromonoside was investigated and confirmed its apoptosis-independent cell death induction in A549 cells. It was suggested that cell death was caused by cell cycle arrest and autophagy induction with signaling pathways involved
EL ESPÍRITU SANTO EN EL PADRE HERNÁN ALESSANDRI
No full textThe present work corresponds to a theological study carried out on the Holy Spirit in the work of Fr. Hernán Alessandri, especially in his extensive book “The evangelizing proposal of Schönstatt”. In this work, the author articulates his pneumatological re-flection around three axes: The Holy Spirit as 1) communion; 2) love; and 3) strength and dynamism that is personalized in Mary.El presente trabajo corresponde a un estudio teológico realizado sobre el Espíritu Santo en la obra del P. Hernán Alessandri, especialmente en su extenso libro “La propuesta evangelizadora de Schönstatt”. En esta obra, el autor articula su reflexión pneumatológica en torno a tres ejes: el Espíritu santo como 1) comunión; 2) amor; y 3) fuerza y dinamismo que se personaliza en María
