567,846 research outputs found
Diagnosi e gestione dell'esordio psicotico nell'infanzia e nell'adolescenza
No full textNonostante la schizofrenia sia generalmente diagnosticata nella prima età adulta, circa il 4% dei casi provenienti da una coorte di nascita manifesterà il disturbo prima dei 18 anni. La Schizofrenia a Esordio Precoce (Early Onset Schizophrenia, EOS), a prescindere che si presenti nell’infanzia (Childhood Onset Schizophrenia, COS) o nell’adolescenza (Adolescent Onset Schizophrenia, AOS), è comunque associata a maggiori anomalie premorbose e decorso clinico ed esito psicosociale scadenti. Questi dati sottolineano l’importanza della diagnosi precoce e di trattamenti efficaci e sicuri per la schizofrenia in età infantile e adolescenziale. Il trattamento di bambini e adolescenti affetti da schizofrenia è particolarmente difficile in termini di ottimizzazione del benessere fisico ed emotivo e del funzionamento sociale, educativo e/o professionale, e anche nel tentativo di ridurre al minimo il carico che la malattia comporta per i pazienti e le loro famiglie. Ci sono lacune significative nella nostra comprensione di come un attuale intervento farmacologico possa interagire con lo sviluppo cognitivo e cerebrale e di come i cambiamenti evolutivi possono avere un impatto sulla risposta al trattamento a lungo termine. Allo stesso modo, i problemi di sicurezza e tollerabilità a lungo termine sono in gran parte irrisolti, nonostante le evidenze degli studi clinici in acuto su una maggiore sensibilità agli effetti collaterali nei pazienti EOS. Forse la sfida più grande è quella di progettare, implementare e valutare modelli di trattamento che vanno al di là del miglioramento sintomatico e si concentrano invece sull’integrazione sociale e sul recovery
A goal programming model to study the impact of R&D expenditures on sustainability-related criteria: the case of Kazakhstan
No full textPurpose: Most countries face important economic, social and environmental challenges and are strongly committed to invest in research and development (R&D) activities to help support the long-run economic sustainable growth. This paper aims to extend the previous research on macro-economic growth models and introduces endogenous variables to determine the amount of investments in R&D activities. Design/methodology/approach: The model considers four different criteria and six economic sectors and aims at finding the optimal allocation of labor across different sectors. The model also endogenously determines the amount of investments in pollution abatement activities together with energy-related R&D efforts. The paper presents an application to the case of Kazakhstan, an emerging Asian country, that aims to become one of the top 30 most developed countries in the world by 2050. Findings: The model shows the limits of the Kazakh agenda that identified too ambitious goals as the country has to go through a sociotechnical transition that involves a range of modifications in institutional structures, together with changes in user practices and the technological dimension. Kazakhstan should invest more in R&D activities able to develop sustainable energy sources to face the current electricity consumption demand and to reduce the greenhouse gas emission in the future. Originality/value: The paper provides valuable knowledge for researchers and policy makers interested in the impact of R&D on the long-run economic sustainable growth
Measurement of the D+/- production asymmetry in 7 TeV pp collisions
No full textThe asymmetry in the production cross-section \sigma of D+/- mesons, A_P = (\sigma(D+) - \sigma(D-))/(\sigma(D+) + \sigma(D-)), is measured in bins of pseudorapidity \eta and transverse momentum p_T within the acceptance of the LHCb detector. The result is obtained with a sample of D+ -> K_S pi+ decays corresponding to an integrated luminosity of 1.0 fb^-1, collected in pp collisions at a centre of mass energy of 7 TeV at the Large Hadron Collider. When integrated over the kinematic range 2.0 K_S pi+ decay is negligible. No significant dependence on \eta or p_T is observed
Libro de actas del Apostolado de la Oración. Asociación erigida canónicamente por él Sr. Luna presbítero D. E. y Martínez en la Parroquia de la Concepción de Tepecoacuilco
No full textLibro de actas del Apostolado de la Oración. Asociación erigida canónicamente por él Sr. Luna presbítero D. E. y Martínez en la Parroquia de la Concepción de Tepecoacuilco, 193
"Proyecto de restablecimiento del corredor inmediato a la Sala de Embajadores. Sección por C-D. (Proyecto)"
No full textCopia, papel, cianotipo, 35x44 cm., 1/50
sector: 2.1.0.0.Numero de plano de la oficina técnica del servicio de conservación: 300, (Alhambra-archivo de planos Nº 300)
DigitalizadoPalacio de Comares. Proyecto de restablecimiento del corredor inmediato a la Sala de Embajadores. Sección por C-D. Proyecto.Unidad Documenta
Prompt charm production in pp collisions at √<span style="text-decoration:overline">s</span>=7 TeV
No full textCharm production at the LHC in pp collisions at s√=7 TeV is studied with the LHCb detector. The decays D0→K−π+, D+→K−π+π+, D⁎+→D0(K−π+)π+, D+s→ϕ(K−K+)π+, Λ+c→pK−π+, and their charge conjugates are analysed in a data set corresponding to an integrated luminosity of 15 nb−1. Differential cross-sections dσ/dpT are measured for prompt production of the five charmed hadron species in bins of transverse momentum and rapidity in the region 0<pT<8 GeV/c and 2.0<y<4.5. Theoretical predictions are compared to the measured differential cross-sections. The integrated cross-sections of the charm hadrons are computed in the above pT-y range, and their ratios are reported. A combination of the five integrated cross-section measurements gives
σ(cc¯)pT<8 GeV/c,2.0<y<4.5=1419±12(stat)±116(syst)±65(frag) μb,
where the uncertainties are statistical, systematic, and due to the fragmentation functions
Search for the decay Bs0→D*∓π±
No full textA search for the decay Bs0→D*∓π± is presented using a data sample corresponding to an integrated luminosity of 1.0 fb-1 of pp collisions collected by LHCb. This decay is expected to be mediated by a W-exchange diagram, with little contribution from rescattering processes, and therefore a measurement of the branching fraction will help us to understand the mechanism behind related decays such as Bs0→π+π- and Bs0→DD̅ . Systematic uncertainties are minimized by using B0→D*∓π± as a normalization channel. We find no evidence for a signal, and set an upper limit on the branching fraction of B(Bs0→D*∓π±)<6.1(7.8)×10-6 at 90% (95%) confidence level
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